MetaADEDB 2.0 @ LMMD
Torsemide
(NGBFQHCMQULJNZ-UHFFFAOYSA-N)
Structure
SMILES
CC(NC(=O)NS(=O)(=O)c1cnccc1Nc1cccc(c1)C)C
Type(s)
Approved
ATC code(s)
C03CA04; G01AE10
Molecular Formula:
C16H20N4O3S
Molecular Weight:
348.420
Log P:
4.4655
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
3
TPSA:
108.57
CAS Number(s):
56211-40-6; 1189375-06-1
Synonym(s)
1.
Torsemide
2.
1-Isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea
3.
1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea
4.
Demadex
5.
Torasemide
External Link(s)
MeSHD000077786
PubChem Compound41781
51371498
BindingDB64107
ChEBI9637
CHEMBLCHEMBL1148
DrugBankDB00214
DrugCentral2708
IUPHAR/BPS Guide to PHARMACOLOGY7312
KEGGdr:D00382
Therapeutic Target DatabaseD0J9XZ
ZINC5823
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 23US FAERS
2HypotensionFAERS: 6SIDER
US FAERS
3DizzinessFAERS: 5SIDER
US FAERS
4Pharmaceutical product complaintFAERS: 5US FAERS
5Product quality issueFAERS: 5US FAERS
6Abdominal discomfortFAERS: 4US FAERS
7DehydrationFAERS: 4OFFSIDES
SIDER
US FAERS
8Incorrect dose administeredFAERS: 4US FAERS
9Product substitution issueFAERS: 4US FAERS
10SomnolenceFAERS: 4US FAERS
11AstheniaFAERS: 3OFFSIDES
SIDER
US FAERS
12Blood glucose increasedFAERS: 3US FAERS
13DeafnessFAERS: 3US FAERS
14DiscomfortFAERS: 3US FAERS
15FlatulenceFAERS: 3US FAERS
16HeadacheFAERS: 3SIDER
US FAERS
17NauseaFAERS: 3SIDER
US FAERS
18Wrong technique in product usage processFAERS: 3US FAERS
19Accidental overdoseFAERS: 2OFFSIDES
US FAERS
20Acute kidney injuryFAERS: 2US FAERS
21Adverse eventFAERS: 2US FAERS
22Chest discomfortFAERS: 2US FAERS
23DiplopiaFAERS: 2US FAERS
24ErythemaFAERS: 2US FAERS
25Feeling abnormalFAERS: 2US FAERS
26MalaiseFAERS: 2US FAERS
27Myocardial InfarctionFAERS: 2US FAERS
28NocturiaFAERS: 2US FAERS
29PemphigusFAERS: 2US FAERS
30PolyuriaFAERS: 2US FAERS
31PruritusFAERS: 2US FAERS
32Stevens-Johnson SyndromeFAERS: 225811541CTD
OFFSIDES
SIDER
US FAERS
33SyncopeFAERS: 2SIDER
US FAERS
34Therapy changeFAERS: 2US FAERS
35ThirstFAERS: 2SIDER
US FAERS
36AlopeciaFAERS: 1US FAERS
37Anaphylactic shockFAERS: 1US FAERS
38Back PainFAERS: 1US FAERS
39Blood creatinine abnormalFAERS: 1US FAERS
40Blood lactate dehydrogenase increasedFAERS: 1OFFSIDES
US FAERS
41Blood potassium decreasedFAERS: 1US FAERS
42Blood potassium increasedFAERS: 1OFFSIDES
US FAERS
43CardiomegalyFAERS: 1US FAERS
44CataractFAERS: 1US FAERS
45Cerebellar infarctionFAERS: 1US FAERS
46CholelithiasisFAERS: 1US FAERS
47ConstipationFAERS: 1SIDER
US FAERS
48Diabetes MellitusFAERS: 1US FAERS
49Diabetes mellitus inadequate controlFAERS: 1US FAERS
50Drug administration errorFAERS: 1US FAERS
51Drug dispensed to wrong patientFAERS: 1US FAERS
52Drug dispensing errorFAERS: 1US FAERS
53Drug dose omissionFAERS: 1US FAERS
54DyspepsiaFAERS: 1SIDER
US FAERS
55DysuriaFAERS: 1US FAERS
56Electrolyte imbalanceFAERS: 1US FAERS
57EosinophiliaFAERS: 1US FAERS
58Erectile dysfunctionFAERS: 1SIDER
US FAERS
59EructationFAERS: 1US FAERS
60FatigueFAERS: 1OFFSIDES
US FAERS
61Fluid overloadFAERS: 1OFFSIDES
US FAERS
62Gamma-Glutamyltransferase IncreasedFAERS: 1OFFSIDES
US FAERS
63Gamma-glutamyltransferase abnormalFAERS: 1US FAERS
64General physical condition abnormalFAERS: 1US FAERS
65GlaucomaFAERS: 1US FAERS
66Immunoglobulins abnormalFAERS: 1US FAERS
67Inappropriate schedule of drug administrationFAERS: 1US FAERS
68InfectionFAERS: 1OFFSIDES
US FAERS
69LethargyFAERS: 1OFFSIDES
US FAERS
70Leukocytoclastic vasculitisFAERS: 1US FAERS
71Medication ErrorFAERS: 1US FAERS
72Memory impairmentFAERS: 1US FAERS
73MyalgiaFAERS: 1SIDER
US FAERS
74Oculomucocutaneous syndromeFAERS: 1US FAERS
75OliguriaFAERS: 1OFFSIDES
US FAERS
76Oropharyngeal discomfortFAERS: 1SIDER
US FAERS
77OtotoxicityFAERS: 1US FAERS
78OverdoseFAERS: 1US FAERS
79PalpitationsFAERS: 1US FAERS
80PancytopeniaFAERS: 1US FAERS
81Peripheral swellingFAERS: 1US FAERS
82Porphyria non-acuteFAERS: 1US FAERS
83Post procedural complicationFAERS: 1US FAERS
84Product prescribing errorFAERS: 1US FAERS
85Product shape issueFAERS: 1US FAERS
86Product size issueFAERS: 1US FAERS
87Product solubility abnormalFAERS: 1US FAERS
88PseudoporphyriaFAERS: 1US FAERS
89PurpuraFAERS: 1US FAERS
90Rash erythematousFAERS: 1US FAERS
91Stool analysis abnormalFAERS: 1US FAERS
92SwellingFAERS: 1US FAERS
93Therapeutic response unexpected with drug substitutionFAERS: 1US FAERS
94Toxic Epidermal NecrolysisFAERS: 1SIDER
US FAERS
95Urinary tract infectionFAERS: 1US FAERS
96VertigoFAERS: 1US FAERS
97VomitingFAERS: 1SIDER
US FAERS
98Weight decreasedFAERS: 1US FAERS
99WheezingFAERS: 1US FAERS
100nervous system disorderFAERS: 1US FAERS
101AcidosisOFFSIDES
102Actinic keratosisOFFSIDES
103Acute respiratory failureOFFSIDES
104Alanine Aminotransferase IncreasedOFFSIDES
105Alcohol consumptionOFFSIDES
106Amaurosis FugaxOFFSIDES
107AngioedemaSIDER
108ArthralgiaSIDER
109ArthritisSIDER
110Ascites7954549CTD
OFFSIDES
111AsthmaOFFSIDES
112Atrial FibrillationSIDER
113Atrial FlutterOFFSIDES
114Atrial tachycardiaOFFSIDES
115Benign Prostatic HyperplasiaOFFSIDES
116Bilirubin conjugated increasedOFFSIDES
117Blood alkaline phosphatase increasedOFFSIDES
118Blood creatinine increasedOFFSIDES
119Blood glucose decreasedOFFSIDES
120Blood homocysteineOFFSIDES
121Blood urea increasedOFFSIDES
122Blood uric acid decreasedOFFSIDES
123BradycardiaOFFSIDES
124Brain natriuretic peptide increasedOFFSIDES
125Bronchoalveolar LavageOFFSIDES
126BronchopneumoniaOFFSIDES
127Candida sepsisOFFSIDES
128Cardioactive drug level increasedOFFSIDES
129Cardiomyopathy, Dilated18154949CTD
130Cardiovascular insufficiencyOFFSIDES
131CellulitisOFFSIDES
132CheilitisOFFSIDES
133Chest PainSIDER
134Choking sensationOFFSIDES
135CholangiolitisOFFSIDES
136ChromaturiaOFFSIDES
137CirrhosisOFFSIDES
138Clostridium difficile colitisOFFSIDES
139ColitisOFFSIDES
140Conjunctival depositOFFSIDES
141Depressed Level of ConsciousnessOFFSIDES
142DermatitisSIDER
143DiabetesOFFSIDES
144DiarrheaOFFSIDES
145Digitalis intoxication (NOS)SIDER
146Disease ProgressionOFFSIDES
147DiverticulitisOFFSIDES
148DrowsinessOFFSIDES
149Duodenal UlcerOFFSIDES
150Dyspnoea exacerbatedOFFSIDES
151Edema1706990
8858624
11530685		CTD
152Ejection Fraction DecreasedOFFSIDES
153Enterococcal infectionOFFSIDES
154EpistaxisOFFSIDES
155ErysipelasOFFSIDES
156Erythema MultiformeSIDER
157ErythropeniaOFFSIDES
158Escherichia urinary tract infectionOFFSIDES
159Fibrosis18154949CTD
160Fistula repairOFFSIDES
161Focal glomerulosclerosisOFFSIDES
162GastroenteritisOFFSIDES
163Gastrointestinal perforationOFFSIDES
164General physical health deteriorationOFFSIDES
165Glutamate dehydrogenase increasedOFFSIDES
166GoutOFFSIDES
SIDER
167Graft lossOFFSIDES
168GranulocytosisOFFSIDES
169Heart failure

View details

11530685
12167392
18001696
19843838
20882198
 		CTD
170Heparin-induced thrombocytopeniaOFFSIDES
171Hepatic artery stenosisOFFSIDES
172HepatotoxicityOFFSIDES
173HyperparathyroidismOFFSIDES
174Hypertensive heart diseaseOFFSIDES
175Immunosuppressant drug levelOFFSIDES
176Increased bronchial secretionOFFSIDES
177Infusion site mobility decreasedOFFSIDES
178Kidney Diseases1706990CTD
179Kidney FailureOFFSIDES
180Labile hypertensionOFFSIDES
181Left atrial dilatationOFFSIDES
182LeukopeniaSIDER
183Lip erosionOFFSIDES
184Liver Cirrhosis1706990CTD
185Liver transplant rejectionOFFSIDES
186Long QT SyndromeOFFSIDES
187LymphedemaOFFSIDES
188MalabsorptionOFFSIDES
189Markedly reduced dietary intakeOFFSIDES
190Metabolic acidosisOFFSIDES
191Multiple MyelomaOFFSIDES
192Muscle abscessOFFSIDES
193Musculoskeletal discomfortSIDER
194MyelodysplasiaOFFSIDES
195NasopharyngitisOFFSIDES
196NervousnessSIDER
197NeuralgiaOFFSIDES
198Oropharyngeal painSIDER
199PainSIDER
200PancreatitisSIDER
201Paraneoplastic pemphigusOFFSIDES
202Pericardial effusionOFFSIDES
203Peripheral arterial occlusive diseaseOFFSIDES
204Portal HypertensionOFFSIDES
205Portal Vein ThrombosisOFFSIDES
206Primary hypogonadismOFFSIDES
207Progesterone receptor assayOFFSIDES
208Protein total decreasedOFFSIDES
209Prothrombin time abnormalOFFSIDES
210Psychomotor skills impairedOFFSIDES
211Pulmonary HypertensionOFFSIDES
212Pulmonary congestionOFFSIDES
213Purulent dischargeOFFSIDES
214QRS axis abnormalOFFSIDES
215Renal tubular atrophyOFFSIDES
216Respiratory FailureOFFSIDES
217Retinal VasculitisOFFSIDES
218RhabdomyolysisOFFSIDES
219RhinitisSIDER
220Rotavirus test positiveOFFSIDES
221Septic ShockOFFSIDES
222ShockSIDER
223Shunt thrombosisSIDER
224Sinus bradycardiaOFFSIDES
225Sjogren's SyndromeOFFSIDES
226Sudden deathOFFSIDES
227Supraventricular tachycardiaOFFSIDES
228Tarsal Tunnel SyndromeOFFSIDES
229TensionSIDER
230ThrombocytopeniaSIDER
231ThrombophlebitisOFFSIDES
232Toxicity to various agentsSIDER
233TracheitisOFFSIDES
234Unresponsive to stimuliOFFSIDES
235Urinary tract infection pseudomonalOFFSIDES
236Vascular insufficiencyOFFSIDES
237Ventricular Dysfunction, Left18001696CTD
238Ventricular FibrillationOFFSIDES
239Ventricular hypokinesiaOFFSIDES
240Vitamin B 12 DeficiencyOFFSIDES
241Weight GainOFFSIDES
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