MetaADEDB 2.0 @ LMMD
Valganciclovir
(WPVFJKSGQUFQAP-GKAPJAKFSA-N)
Structure
SMILES
OCC(OCn1cnc2c1nc(N)[nH]c2=O)COC(=O)[C@H](C(C)C)N
Type(s)
Approved; Investigational
ATC code(s)
J05AB14
Molecular Formula:
C14H22N6O5
Molecular Weight:
354.362
Log P:
-0.1552
Hydrogen Bond Acceptor:
10
Hydrogen Bond Donor:
4
TPSA:
171.37
CAS Number(s):
175865-60-8
Synonym(s)
1.
Valganciclovir
2.
Ganciclovir L-valyl Ester
3.
Valcyt
4.
Valcyte
5.
Valganciclovir Hydrochloride
6.
Ganciclovir L valyl Ester
External Link(s)
MeSHD000077562
PubChem Compound135413535
64147
ChEBI63635
CHEMBLCHEMBL1201314
DrugBankDB01610
DrugCentral2801
IUPHAR/BPS Guide to PHARMACOLOGY4716
KEGGdr:D02495
Therapeutic Target DatabaseD06GWF
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Intentional product use issueFAERS: 36US FAERS
2Drug resistanceFAERS: 9US FAERS
3NeutropeniaFAERS: 911465875CTD
SIDER
US FAERS
4No adverse eventFAERS: 7US FAERS
5PneumoniaFAERS: 6SIDER
US FAERS
6Blood creatinine increasedFAERS: 4OFFSIDES
SIDER
US FAERS
7CellulitisFAERS: 4OFFSIDES
US FAERS
8Cerebrovascular accidentFAERS: 4US FAERS
9HaematotoxicityFAERS: 4US FAERS
10PancytopeniaFAERS: 4SIDER
US FAERS
11Cytomegalovirus test positiveFAERS: 3US FAERS
12FatigueFAERS: 3SIDER
US FAERS
13InfectionFAERS: 3SIDER
US FAERS
14Product storage errorFAERS: 3US FAERS
15Product use issueFAERS: 3US FAERS
16SepsisFAERS: 3SIDER
US FAERS
17Drug ineffectiveFAERS: 2US FAERS
18Flank PainFAERS: 2OFFSIDES
US FAERS
19Gamma-Glutamyltransferase IncreasedFAERS: 2US FAERS
20GastritisFAERS: 2SIDER
US FAERS
21HepatotoxicityFAERS: 2US FAERS
22Intercepted medication errorFAERS: 2US FAERS
23LeukopeniaFAERS: 2SIDER
US FAERS
24LymphomaFAERS: 2US FAERS
25MalaiseFAERS: 2SIDER
US FAERS
26Status EpilepticusFAERS: 2US FAERS
27TachycardiaFAERS: 2SIDER
US FAERS
28Therapy cessationFAERS: 2US FAERS
29Weight decreasedFAERS: 2SIDER
US FAERS
30Acute respiratory failureFAERS: 1OFFSIDES
US FAERS
31AgranulocytosisFAERS: 1US FAERS
32Alanine Aminotransferase IncreasedFAERS: 1US FAERS
33AngioedemaFAERS: 1US FAERS
34Back PainFAERS: 1SIDER
US FAERS
35BedriddenFAERS: 1US FAERS
36Bile Duct StenosisFAERS: 1US FAERS
37BlindnessFAERS: 1SIDER
US FAERS
38Cardiac dysfunctionFAERS: 1US FAERS
39Cerebral disorderFAERS: 1US FAERS
40Clostridium difficile infectionFAERS: 1US FAERS
41Cystitis viralFAERS: 1US FAERS
42Cytomegalovirus gastrointestinal infectionFAERS: 1US FAERS
43EcthymaFAERS: 1US FAERS
44EncephalitisFAERS: 1OFFSIDES
US FAERS
45Febrile NeutropeniaFAERS: 1US FAERS
46Gastric LavageFAERS: 1US FAERS
47Glioblastoma MultiformeFAERS: 1US FAERS
48HepatitisFAERS: 1OFFSIDES
SIDER
US FAERS
49HypercreatinaemiaFAERS: 1US FAERS
50HypercreatininaemiaFAERS: 1US FAERS
51HypersensitivityFAERS: 1SIDER
US FAERS
52Incorrect drug dosage form administeredFAERS: 1US FAERS
53Intercepted product storage errorFAERS: 1US FAERS
54Joint swellingFAERS: 1US FAERS
55Lyme DiseaseFAERS: 1US FAERS
56Malignant neoplasm progressionFAERS: 1US FAERS
57Myocardial InfarctionFAERS: 1US FAERS
58Neutrophil count decreasedFAERS: 1US FAERS
59OverdoseFAERS: 1US FAERS
60Peripheral swellingFAERS: 1US FAERS
61Post procedural cellulitisFAERS: 1US FAERS
62Prescribed underdoseFAERS: 1US FAERS
63Product substitution issueFAERS: 1US FAERS
64Product use in unapproved indicationFAERS: 1US FAERS
65Renal graft infectionFAERS: 1US FAERS
66Septic ShockFAERS: 1US FAERS
67Sudden Cardiac DeathFAERS: 1US FAERS
68ThrombocytopeniaFAERS: 111465875CTD
SIDER
US FAERS
69TransplantFAERS: 1US FAERS
70Unevaluable eventFAERS: 1US FAERS
71Viral mutation identifiedFAERS: 1US FAERS
72treatment failureFAERS: 1US FAERS
73Abdominal AbscessOFFSIDES
74Abdominal Pain11465875CTD
OFFSIDES
SIDER
75Abdominal sepsisOFFSIDES
76Abnormal visionSIDER
77AcneSIDER
78Acute prerenal failureOFFSIDES
79Adverse eventOFFSIDES
80AgitationSIDER
81AlopeciaSIDER
82AmblyopiaSIDER
83Ammonia increasedOFFSIDES
84AmnesiaOFFSIDES
SIDER
85Anaphylactic shockSIDER
86Anemia11465875CTD
87AnhedoniaOFFSIDES
88AnorexiaSIDER
89AnxietySIDER
90ArthralgiaSIDER
91Ascites infectionOFFSIDES
92AscitesOFFSIDES
SIDER
93AspergillosisOFFSIDES
94AstheniaOFFSIDES
SIDER
95AtaxiaSIDER
96BK virus infectionOFFSIDES
97Bacterial sepsisOFFSIDES
98Blood albumin decreasedOFFSIDES
99Blood alkaline phosphatase increasedSIDER
100Blood and lymphatic system disordersSIDER
101Blood count abnormalOFFSIDES
102Blood creatine phosphokinase increasedSIDER
103Blood creatinine decreasedSIDER
104Blood glucose decreasedSIDER
105Blood glucose fluctuationOFFSIDES
106Blood lactate dehydrogenase increasedSIDER
107Blood potassium increasedOFFSIDES
108Blood triglycerides increasedOFFSIDES
109Blood urea increasedOFFSIDES
110Blood uric acidOFFSIDES
111Blood urine presentOFFSIDES
SIDER
112Bone marrow depressionSIDER
113BronchitisSIDER
114BronchopneumoniaOFFSIDES
115CD4 Lymphocytes DecreasedOFFSIDES
116CYTOMEGALOVIRUS ANTIGENOFFSIDES
117CachexiaSIDER
118Catheter related infectionSIDER
119Catheter site erythemaOFFSIDES
120Chemotherapeutic drug level increasedOFFSIDES
121ChillsSIDER
122CholangiolitisOFFSIDES
123CholangitisSIDER
124CholecystitisOFFSIDES
125Clostridium colitisOFFSIDES
126ClumsinessOFFSIDES
127Cold sweatOFFSIDES
128ConstipationSIDER
129Creatinine lowSIDER
130Cytomegalovirus Retinitis11465875CTD
131Cytomegalovirus chorioretinitisOFFSIDES
132Cytomegalovirus hepatitisOFFSIDES
133Cytomegalovirus syndromeSIDER
134DeafnessSIDER
135DehydrationSIDER
136DemyelinationOFFSIDES
137DermatitisSIDER
138Device dislocationOFFSIDES
139Device related infectionSIDER
140Diabetes MellitusSIDER
141Diabetes mellitus inadequate controlOFFSIDES
142Diarrhea11465875CTD
OFFSIDES
143DiscomfortSIDER
144Disturbance in sexual arousalSIDER
145DizzinessSIDER
146Drug toxicityOFFSIDES
147Dry skinSIDER
148DysgeusiaSIDER
149DyspepsiaSIDER
150DysuriaSIDER
151Ear and labyrinth disordersSIDER
152Ear dischargeOFFSIDES
153Emotional disorderSIDER
154Emotional distressOFFSIDES
155EmpyemaOFFSIDES
156Enterococcal infectionOFFSIDES
157EosinophiliaSIDER
158Eosinophilic myocarditisOFFSIDES
159Erectile dysfunctionSIDER
160EructationSIDER
161ErythemaOFFSIDES
162ErythropeniaOFFSIDES
163Escherichia infectionOFFSIDES
164Extremity contractureOFFSIDES
165Eye painSIDER
166Failure to ThriveOFFSIDES
167Feeling abnormalSIDER
168Fever11465875CTD
169FlatulenceSIDER
170Fluid overloadOFFSIDES
171Focal glomerulosclerosisOFFSIDES
172Gastrointestinal PainSIDER
173General physical health deteriorationOFFSIDES
174GlaucomaSIDER
175Graft infectionOFFSIDES
176GranulomaOFFSIDES
177Headache11465875CTD
SIDER
178Hepatic artery thrombosisOFFSIDES
179Hepatitis COFFSIDES
180HydronephrosisOFFSIDES
181HyperpigmentationOFFSIDES
182HypotensionSIDER
183HypoxiaOFFSIDES
184Immune reconstitution syndromeOFFSIDES
185Immunosuppressant drug levelOFFSIDES
186ImmunosuppressionOFFSIDES
187InfestationSIDER
188InfluenzaSIDER
189Infusion site mobility decreasedOFFSIDES
190Iron OverloadOFFSIDES
191Joint Range of Motion DecreasedOFFSIDES
192Joint stiffnessOFFSIDES
193Jugular vein distensionOFFSIDES
194Kidney FailureOFFSIDES
195LacerationOFFSIDES
196Lactic dehydrogenase activity increasedSIDER
197LeukocytosisSIDER
198Leukopenia neonatalOFFSIDES
199Limb discomfortOFFSIDES
200Liver AbscessOFFSIDES
201Liver transplant rejectionOFFSIDES
202Lung consolidationOFFSIDES
203LymphadenopathySIDER
204LymphoceleOFFSIDES
205MalnutritionSIDER
206Mental status changesOFFSIDES
207Muscle WeaknessOFFSIDES
208Muscle tightnessOFFSIDES
209Musculoskeletal PainSIDER
210Musculoskeletal discomfortOFFSIDES
SIDER
211Musculoskeletal stiffnessOFFSIDES
212Myasthenic SyndromeSIDER
213Mycobacterium avium complex immune restoration diseaseOFFSIDES
214MyoclonusSIDER
215NasopharyngitisOFFSIDES
SIDER
216Nausea11465875CTD
SIDER
217Necrotising granulomatous lymphadenitisOFFSIDES
218Nephrogenic Fibrosing DermopathyOFFSIDES
219NephrolithiasisOFFSIDES
220NervousnessSIDER
221Night sweatsSIDER
222OliguriaOFFSIDES
223Oral candidiasisSIDER
224Oropharyngeal discomfortSIDER
225Oropharyngeal painSIDER
226Pain of skinOFFSIDES
227PainSIDER
228PancreatitisSIDER
229Paresthesia11465875CTD
230Pericardial effusionOFFSIDES
231Pericarditis mycoplasmalOFFSIDES
232PericarditisOFFSIDES
233Peripheral Nervous System Diseases11465875CTD
234PharyngitisSIDER
235PhlebitisSIDER
236PityriasisOFFSIDES
237Pneumatic compression therapyOFFSIDES
238PneumothoraxOFFSIDES
239Portal HypertensionOFFSIDES
240Post procedural bile leakOFFSIDES
241Post procedural complicationSIDER
242Postoperative renal failureOFFSIDES
243Procedural complicationSIDER
244Productive CoughSIDER
245Protein S decreasedOFFSIDES
246PruritusSIDER
247Pulmonary vascular disorderOFFSIDES
248PyelonephritisOFFSIDES
249QuadriparesisOFFSIDES
250Quality of life decreasedOFFSIDES
251Renal tubular atrophyOFFSIDES
252Renal tubular disorderOFFSIDES
253Renal tubular necrosisOFFSIDES
254Respiratory FailureOFFSIDES
255Retinal Detachment11465875CTD
SIDER
256ScotomaOFFSIDES
257SeromaOFFSIDES
258SinusitisSIDER
259Skin IndurationOFFSIDES
260Skin hypertrophyOFFSIDES
261Skin lesionOFFSIDES
262Skin tightnessOFFSIDES
263Sleep Initiation and Maintenance Disorders11465875CTD
264SomnolenceSIDER
265SplenomegalySIDER
266Sputum culture positiveOFFSIDES
267StomatitisSIDER
268TensionSIDER
269Therapy non-responderOFFSIDES
270ThrombophlebitisSIDER
271TinnitusSIDER
272TremorSIDER
273Urinary tract infection enterococcalOFFSIDES
274Urinary tract infection pseudomonalOFFSIDES
275Urinary tract infectionSIDER
276UrticariaSIDER
277Ventricular arrhythmiaSIDER
278VertigoSIDER
279Viral test positiveOFFSIDES
280Visual ImpairmentSIDER
281Vitreous floatersSIDER
282Vomiting11465875CTD
SIDER
283Wound InfectionOFFSIDES
284Wound decompositionOFFSIDES
285Wound dehiscenceSIDER
286Wound discharge increasedSIDER
287effusionOFFSIDES
288jaundiceSIDER
289nervous system disorderSIDER
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