MetaADEDB 2.0 @ LMMD
Rifampin
(JQXXHWHPUNPDRT-WLSIYKJHSA-N)
Structure
SMILES
CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c2c(O)c(/C=N/N4CCN(CC4)C)c(c(c2c(c3C)O)O)NC(=O)/C(=C\C=C\[C@@H]([C@@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]1C)OC(=O)C)C)O)C)O)C)/C
Type(s)
Approved
ATC code(s)
J04AB02; J04AM02; J04AM05; J04AM06; J04AM07
Molecular Formula:
C43H58N4O12
Molecular Weight:
822.940
Log P:
4.3492
Hydrogen Bond Acceptor:
16
Hydrogen Bond Donor:
6
TPSA:
220.15
CAS Number(s):
13292-46-1
Synonym(s)
1.
Rifampin
2.
Rifampicin
3.
Benemycin
4.
Rifadin
5.
Rimactan
6.
Rimactane
7.
Tubocin
External Link(s)
MeSHD012293
PubChem Compound136262914
135398735
5381226
BindingDB50370232
ChEBI28077
71365
CHEMBLCHEMBL374478
DrugBankDB01045
DrugCentral2377
KEGGcpd:C06688
dr:D00211
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1VomitingFAERS: 35
Canada Vigilance: 11
869341CTD
SIDER
Canada Vigilance
US FAERS
2NauseaFAERS: 34
Canada Vigilance: 10
Canada Vigilance
OFFSIDES
SIDER
US FAERS
3Abdominal PainFAERS: 18
Canada Vigilance: 2
Canada Vigilance
US FAERS
4AstheniaFAERS: 17
Canada Vigilance: 3
Canada Vigilance
SIDER
US FAERS
5jaundiceFAERS: 17
Canada Vigilance: 4

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CTD
SIDER
Canada Vigilance
US FAERS
6CholestasisFAERS: 16

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CTD
US FAERS
7ChromaturiaFAERS: 16OFFSIDES
US FAERS
8Acute kidney injuryFAERS: 14

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CTD
US FAERS
9HeadacheFAERS: 14
Canada Vigilance: 9
19550071CTD
SIDER
Canada Vigilance
US FAERS
10HypothyroidismFAERS: 14US FAERS
11NeutropeniaFAERS: 14US FAERS
12ThrombocytopeniaFAERS: 14
Canada Vigilance: 3

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CTD
SIDER
Canada Vigilance
US FAERS
13Alanine Aminotransferase IncreasedFAERS: 13
Canada Vigilance: 1
Canada Vigilance
US FAERS
14FatigueFAERS: 12
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
15Aspartate Aminotransferase IncreasedFAERS: 11US FAERS
16Deep Vein ThrombosisFAERS: 11US FAERS
17HypersensitivityFAERS: 11SIDER
US FAERS
18HypotensionFAERS: 11US FAERS
19MalaiseFAERS: 11
Canada Vigilance: 1
Canada Vigilance
US FAERS
20PruritusFAERS: 11
Canada Vigilance: 1
1587427
9732934
CTD
SIDER
Canada Vigilance
US FAERS
21MyalgiaFAERS: 10US FAERS
22TachycardiaFAERS: 10US FAERS
23UrticariaFAERS: 10
Canada Vigilance: 3
11792017CTD
SIDER
Canada Vigilance
US FAERS
24Blood alkaline phosphatase increasedFAERS: 9US FAERS
25ChillsFAERS: 9SIDER
US FAERS
26DizzinessFAERS: 8SIDER
US FAERS
27Drug resistanceFAERS: 8OFFSIDES
US FAERS
28PainFAERS: 8OFFSIDES
SIDER
US FAERS
29Pulmonary EmbolismFAERS: 8US FAERS
30Toxic Epidermal NecrolysisFAERS: 8SIDER
US FAERS
31ArthralgiaFAERS: 72915734CTD
US FAERS
32Disease recurrenceFAERS: 7US FAERS
33Disseminated Intravascular CoagulationFAERS: 71811361
6222344
CTD
SIDER
US FAERS
34Drug ineffectiveFAERS: 7OFFSIDES
US FAERS
35LeukopeniaFAERS: 7
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
36Product use in unapproved indicationFAERS: 7US FAERS
37Weight decreasedFAERS: 7US FAERS
38Autoimmune thyroiditisFAERS: 6US FAERS
39EosinophiliaFAERS: 6SIDER
US FAERS
40Eosinophilic PneumoniaFAERS: 6US FAERS
41HepatitisFAERS: 6
Canada Vigilance: 1

View details

CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
42PancytopeniaFAERS: 6US FAERS
43Pathogen resistanceFAERS: 6US FAERS
44Stevens-Johnson SyndromeFAERS: 625811541CTD
OFFSIDES
SIDER
US FAERS
45TremorFAERS: 6
Canada Vigilance: 1
Canada Vigilance
US FAERS
46Anaphylactic shockFAERS: 5SIDER
US FAERS
47EpistaxisFAERS: 5US FAERS
48Gene MutationFAERS: 5US FAERS
49PetechiaeFAERS: 5US FAERS
50Toxicity to various agentsFAERS: 5US FAERS
51ErythemaFAERS: 4US FAERS
52HepatotoxicityFAERS: 4
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
53Intestinal ObstructionFAERS: 4US FAERS
54Multi-organ disorderFAERS: 4US FAERS
55Myocardial InfarctionFAERS: 4US FAERS
56PancreatitisFAERS: 416236685CTD
US FAERS
57Product quality issueFAERS: 4US FAERS
58Respiratory distressFAERS: 4US FAERS
59Transaminases increasedFAERS: 4US FAERS
60Unresponsive to stimuliFAERS: 4OFFSIDES
US FAERS
61VertigoFAERS: 4US FAERS
62Visual ImpairmentFAERS: 4
Canada Vigilance: 6
Canada Vigilance
SIDER
US FAERS
63Vitamin D DeficiencyFAERS: 4US FAERS
64Abdominal discomfortFAERS: 3SIDER
US FAERS
65Administration site extravasationFAERS: 3US FAERS
66AgitationFAERS: 3US FAERS
67AlopeciaFAERS: 3US FAERS
68Back PainFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
69Chest PainFAERS: 3
Canada Vigilance: 2
Canada Vigilance
US FAERS
70Drug dispensing errorFAERS: 3US FAERS
71Feeling abnormalFAERS: 3SIDER
US FAERS
72FlushingFAERS: 3SIDER
US FAERS
73Gamma-Glutamyltransferase IncreasedFAERS: 3US FAERS
74LymphadenopathyFAERS: 3US FAERS
75Mental impairmentFAERS: 3US FAERS
76Metabolic acidosisFAERS: 3OFFSIDES
US FAERS
77NeuropathyFAERS: 3US FAERS
78PalpitationsFAERS: 3US FAERS
79Paradoxical drug reactionFAERS: 3US FAERS
80PeriarthritisFAERS: 3US FAERS
81PurpuraFAERS: 3SIDER
US FAERS
82Respiratory FailureFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
83SepsisFAERS: 32488482CTD
US FAERS
84ShockFAERS: 39827298CTD
SIDER
US FAERS
85WheezingFAERS: 3SIDER
US FAERS
86Wrong technique in product usage processFAERS: 3US FAERS
87AngioedemaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
88Anti-neutrophil cytoplasmic antibody positive vasculitisFAERS: 2US FAERS
89AnxietyFAERS: 2US FAERS
90Bilirubin conjugated increasedFAERS: 2US FAERS
91Blood creatinine increasedFAERS: 2OFFSIDES
US FAERS
92Blood urine presentFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
93Bone painFAERS: 2SIDER
US FAERS
94Brain DeathFAERS: 2US FAERS
95Cardiac ArrestFAERS: 2US FAERS
96CholelithiasisFAERS: 26452153CTD
US FAERS
97Clostridium colitisFAERS: 2US FAERS
98ConstipationFAERS: 2US FAERS
99CryingFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
100DehydrationFAERS: 2US FAERS
101Depressed Level of ConsciousnessFAERS: 2OFFSIDES
US FAERS
102DyspepsiaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
103Hepatic EncephalopathyFAERS: 21079531
11316203
21224054
CTD
US FAERS
104Hepatic necrosisFAERS: 2US FAERS
105HepatomegalyFAERS: 27337308
28108177
CTD
US FAERS
106HyperleukocytosisFAERS: 2US FAERS
107HypophagiaFAERS: 2OFFSIDES
US FAERS
108Impaired work abilityFAERS: 2OFFSIDES
US FAERS
109Lip swellingFAERS: 2US FAERS
110Medication ErrorFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
111Mental status changesFAERS: 2US FAERS
112Mononucleosis syndromeFAERS: 2US FAERS
113Mood swingsFAERS: 2US FAERS
114Musculoskeletal PainFAERS: 2US FAERS
115Neck PainFAERS: 2US FAERS
116NephritisFAERS: 2US FAERS
117Nephrotic SyndromeFAERS: 2
Canada Vigilance: 1
809900
2782777
6837651
CTD
Canada Vigilance
US FAERS
118NervousnessFAERS: 2US FAERS
119No adverse eventFAERS: 2US FAERS
120Oral painFAERS: 2SIDER
US FAERS
121Oropharyngeal painFAERS: 2OFFSIDES
US FAERS
122PallorFAERS: 2
Canada Vigilance: 2
Canada Vigilance
US FAERS
123PemphigusFAERS: 2SIDER
US FAERS
124Peripheral swellingFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
125PneumoniaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
126PsoriasisFAERS: 2US FAERS
127Septic ShockFAERS: 2OFFSIDES
US FAERS
128SyncopeFAERS: 2US FAERS
129Vascular purpuraFAERS: 2SIDER
US FAERS
130Visual disturbanceFAERS: 2SIDER
US FAERS
131AbasiaFAERS: 1US FAERS
132Accidental overdoseFAERS: 1US FAERS
133AcidosisFAERS: 1US FAERS
134AcneFAERS: 1US FAERS
135Acquired gene mutationFAERS: 1US FAERS
136Acute graft versus host disease in skinFAERS: 1US FAERS
137Acute left ventricular failureFAERS: 1US FAERS
138Acute myocardial infarctionFAERS: 1OFFSIDES
US FAERS
139AgranulocytosisFAERS: 119274991
20140364
CTD
SIDER
US FAERS
140Alopecia AreataFAERS: 1US FAERS
141Altered state of consciousnessFAERS: 1OFFSIDES
US FAERS
142Anaphylactoid ReactionFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
143AngerFAERS: 1US FAERS
144AnorexiaFAERS: 1869341CTD
SIDER
US FAERS
145Anti-platelet antibody positiveFAERS: 1US FAERS
146Aphthous StomatitisFAERS: 1US FAERS
147ApoptosisFAERS: 1US FAERS
148AscitesFAERS: 1US FAERS
149AsterixisFAERS: 1OFFSIDES
US FAERS
150AtaxiaFAERS: 1SIDER
US FAERS
151Atrial FibrillationFAERS: 1US FAERS
152Autoimmune thrombocytopeniaFAERS: 1US FAERS
153Blood amylase increasedFAERS: 1US FAERS
154Blood cortisol decreasedFAERS: 1US FAERS
155Blood creatine phosphokinase increasedFAERS: 1US FAERS
156Blood lactate dehydrogenase increasedFAERS: 1US FAERS
157Blood phosphorus decreasedFAERS: 1US FAERS
158Blood pressure immeasurableFAERS: 1US FAERS
159Blood pressure inadequately controlledFAERS: 1OFFSIDES
US FAERS
160Blood sodium decreasedFAERS: 1US FAERS
161Bronchopulmonary AspergillosisFAERS: 1US FAERS
162CalcinosisFAERS: 1US FAERS
163Carotid pulse decreasedFAERS: 1US FAERS
164Cerebral vasoconstrictionFAERS: 1US FAERS
165Cerebrovascular accidentFAERS: 1US FAERS
166Chest discomfortFAERS: 1US FAERS
167CholangitisFAERS: 1US FAERS
168Coagulation factor V level decreasedFAERS: 1US FAERS
169Contraindicated product administeredFAERS: 1US FAERS
170CystitisFAERS: 1US FAERS
171CytopeniaFAERS: 1US FAERS
172DeafnessFAERS: 1US FAERS
173DeliriumFAERS: 1US FAERS
174DementiaFAERS: 1US FAERS
175Diffuse alveolar damageFAERS: 1US FAERS
176DiplopiaFAERS: 1US FAERS
177Disease ProgressionFAERS: 1OFFSIDES
US FAERS
178DisorientationFAERS: 1US FAERS
179Drug DependenceFAERS: 1US FAERS
180Drug administration errorFAERS: 1US FAERS
181Drug exposure during pregnancyFAERS: 1US FAERS
182Drug ineffective for unapproved indicationFAERS: 1US FAERS
183Drug level below therapeuticFAERS: 1US FAERS
184Drug level decreasedFAERS: 1US FAERS
185Drug prescribing errorFAERS: 1US FAERS
186Drug toxicityFAERS: 1OFFSIDES
US FAERS
187Drug withdrawal syndromeFAERS: 1US FAERS
188DysbacteriosisFAERS: 1US FAERS
189DysenteryFAERS: 1US FAERS
190Echocardiogram abnormalFAERS: 1US FAERS
191Enzyme abnormalityFAERS: 1US FAERS
192Erectile dysfunctionFAERS: 1US FAERS
193Erythrodermic psoriasisFAERS: 1US FAERS
194Escherichia urinary tract infectionFAERS: 1US FAERS
195Expired product administeredFAERS: 1US FAERS
196Eye painFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
197Failure to ThriveFAERS: 1US FAERS
198Fat intoleranceFAERS: 1US FAERS
199Feeling of body temperature changeFAERS: 1US FAERS
200FibrosisFAERS: 1US FAERS
201Flank PainFAERS: 1US FAERS
202Food AllergyFAERS: 1US FAERS
203General physical health deteriorationFAERS: 1US FAERS
204GoutFAERS: 1US FAERS
205Heart sounds abnormalFAERS: 1US FAERS
206Heparin-induced thrombocytopeniaFAERS: 1US FAERS
207Hepatitis B core antibody positiveFAERS: 1US FAERS
208Hepatitis B surface antibody positiveFAERS: 1US FAERS
209HepatosplenomegalyFAERS: 1OFFSIDES
US FAERS
210Hilar lymphadenopathyFAERS: 1US FAERS
211HydrothoraxFAERS: 1OFFSIDES
US FAERS
212HypertransaminasaemiaFAERS: 1US FAERS
213HyperventilationFAERS: 1US FAERS
214HypokinesiaFAERS: 1OFFSIDES
US FAERS
215Hypothalamo-pituitary disorderFAERS: 1US FAERS
216ImmobileFAERS: 1US FAERS
217Immune reconstitution syndromeFAERS: 1OFFSIDES
US FAERS
218ImpetigoFAERS: 1US FAERS
219IncoherentFAERS: 1US FAERS
220Incorrect dose administeredFAERS: 1US FAERS
221Incorrect drug administration rateFAERS: 1US FAERS
222InfectionFAERS: 1US FAERS
223Infusion site injuryFAERS: 1US FAERS
224Injection site extravasationFAERS: 1US FAERS
225Intentional product misuseFAERS: 1US FAERS
226Intentional self-injuryFAERS: 1US FAERS
227Intercepted medication errorFAERS: 1US FAERS
228Intestinal PerforationFAERS: 1US FAERS
229LethargyFAERS: 1US FAERS
230LeukocytosisFAERS: 111837753CTD
US FAERS
231LeukoencephalomyelitisFAERS: 1US FAERS
232Libido disorderFAERS: 1US FAERS
233Lipase increasedFAERS: 1US FAERS
234Lymphocyte count decreasedFAERS: 1US FAERS
235Lymphocyte stimulation test positiveFAERS: 1US FAERS
236MelanosisFAERS: 1US FAERS
237Middle insomniaFAERS: 1US FAERS
238Morbid thoughtsFAERS: 1US FAERS
239Multiple sclerosis relapseFAERS: 1US FAERS
240NasopharyngitisFAERS: 1US FAERS
241Neutrophil count decreasedFAERS: 1US FAERS
242NocturiaFAERS: 1US FAERS
243Optic NeuropathyFAERS: 1US FAERS
244Oropharyngeal discomfortFAERS: 1US FAERS
245OtotoxicityFAERS: 1OFFSIDES
US FAERS
246OverdoseFAERS: 1US FAERS
247Paratracheal lymphadenopathyFAERS: 1US FAERS
248Paresis anal sphincterFAERS: 1US FAERS
249PhlebitisFAERS: 1US FAERS
250Pigment nephropathyFAERS: 1US FAERS
251Pleuritic painFAERS: 1US FAERS
252PneumonitisFAERS: 1US FAERS
253PoisoningFAERS: 1US FAERS
254Polymyalgia RheumaticaFAERS: 1US FAERS
255Post procedural complicationFAERS: 1US FAERS
256PresyncopeFAERS: 1US FAERS
257Primary Adrenal InsufficiencyFAERS: 1US FAERS
258Product dispensing errorFAERS: 1US FAERS
259Product name confusionFAERS: 1US FAERS
260Product substitution issueFAERS: 1US FAERS
261Product use issueFAERS: 1US FAERS
262Productive CoughFAERS: 1US FAERS
263ProteinuriaFAERS: 1
Canada Vigilance: 1

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CTD
Canada Vigilance
US FAERS
264Prothrombin level decreasedFAERS: 1US FAERS
265PurulenceFAERS: 1OFFSIDES
US FAERS
266QuadriparesisFAERS: 1OFFSIDES
US FAERS
267Red man syndromeFAERS: 1OFFSIDES
US FAERS
268Renal tubular necrosisFAERS: 1SIDER
US FAERS
269Respiratory arrestFAERS: 1US FAERS
270Respiratory tract congestionFAERS: 1US FAERS
271RetchingFAERS: 1US FAERS
272Retinal DetachmentFAERS: 1US FAERS
273RhabdomyolysisFAERS: 1US FAERS
274Rheumatoid ArthritisFAERS: 1US FAERS
275SarcoidosisFAERS: 1US FAERS
276Secretion dischargeFAERS: 1US FAERS
277Shock symptomFAERS: 1US FAERS
278Sjogren's SyndromeFAERS: 1US FAERS
279Skin lesionFAERS: 1US FAERS
280Skin necrosisFAERS: 1US FAERS
281SomnolenceFAERS: 1SIDER
US FAERS
282Splenic abscessFAERS: 1US FAERS
283StomatitisFAERS: 1US FAERS
284StridorFAERS: 1OFFSIDES
US FAERS
285Sudden deathFAERS: 1US FAERS
286Suicide attemptFAERS: 1US FAERS
287SwellingFAERS: 1US FAERS
288Therapeutic product effect decreasedFAERS: 1US FAERS
289Throat irritationFAERS: 1US FAERS
290Thrombocytopenic purpuraFAERS: 1US FAERS
291ThrombocytosisFAERS: 1US FAERS
292TinnitusFAERS: 1US FAERS
293Tongue pigmentationFAERS: 1US FAERS
294Tooth ExtractionFAERS: 1OFFSIDES
US FAERS
295Ultrasound abdomen abnormalFAERS: 1US FAERS
296Unevaluable eventFAERS: 1US FAERS
297Urinary RetentionFAERS: 1US FAERS
298Urinary tract infectionFAERS: 1US FAERS
299Urine calcium decreasedFAERS: 1US FAERS
300Urine delta aminolevulinateFAERS: 1US FAERS
301Urine porphobilinogen increasedFAERS: 1US FAERS
302White blood cell count decreasedFAERS: 1US FAERS
303X-ray of pelvis and hip abnormalFAERS: 1US FAERS
304Abdominal massOFFSIDES
305Abnormal visionOFFSIDES
306Acid fast bacilli infectionOFFSIDES
307Acid refluxOFFSIDES
308ActinomycosisOFFSIDES
309Acute Coronary SyndromeOFFSIDES
310Acute haemolytic anaemiaSIDER
311Acute interstitial nephritisSIDER
312AdenitisOFFSIDES
313Adverse eventOFFSIDES
314AgraphiaOFFSIDES
315Alcoholic IntoxicationOFFSIDES
316AnalgesiaOFFSIDES
317Anemia, Hemolytic

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CTD
318Anemia11837753
12324902
CTD
319Angina Pectoris, Variant3453828CTD
320Angiotensin converting enzyme increasedOFFSIDES
321Antiphospholipid antibodies positiveOFFSIDES
322Anuria

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CTD
OFFSIDES
323Arthritis2915734CTD
324Arthropod biteOFFSIDES
325Autoimmune hepatitisOFFSIDES
326Azotemia76779CTD
327Bacteria sputum identifiedOFFSIDES
328Bacterial test positiveOFFSIDES
329BicytopeniaOFFSIDES
330Bladder painCanada Vigilance: 1Canada Vigilance
331Blindness4059141CTD
332Blood GlucoseOFFSIDES
333Blood albumin decreasedOFFSIDES
334Blood and lymphatic system disordersSIDER
335Blood potassium decreasedOFFSIDES
336Bone lesionOFFSIDES
337Brain Abscess21063978CTD
338Brain Diseases20305954CTD
339BronchitisOFFSIDES
340Brucellosis16236685
18445910
19861876
CTD
341BursitisOFFSIDES
342CSF bacteria identifiedOFFSIDES
343CYTOMEGALOVIRUS ANTIGENOFFSIDES
344Cardioactive drug levelOFFSIDES
345Cataract operationOFFSIDES
346Cavernous Sinus Thrombosis18380704CTD
347CellulitisOFFSIDES
348Cerebral Infarction9827298CTD
349CheilitisOFFSIDES
350Chemical and Drug Induced Liver Injury

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CTD
351CholangiolitisOFFSIDES
352Compression fractureOFFSIDES
353Congenital mitochondrial cytopathyOFFSIDES
354Conjunctival depositOFFSIDES
355ConjunctivitisSIDER
356Consciousness Disorders830577CTD
357Cor pulmonaleOFFSIDES
358Cord blood transplant therapyOFFSIDES
359Corynebacterium Infections16144879CTD
360Cubital Tunnel SyndromeOFFSIDES
361Cutaneous hypersensitivitySIDER
362Cytolytic hepatitisOFFSIDES
363Dental FistulaOFFSIDES
364DermatitisSIDER
365Diarrhea24101390CTD
366Discitis19718264CTD
367DrowsinessSIDER
368Drug Eruptions7786350
11579651
11792017
CTD
369DysbiosisCanada Vigilance: 1Canada Vigilance
370EcthymaOFFSIDES
371Edema1587427CTD
372Ejection Fraction DecreasedOFFSIDES
373Endocarditis6915109CTD
OFFSIDES
374Engraft failureOFFSIDES
375Eosinophilic myocarditisOFFSIDES
376Epigastric distressSIDER
377ErysipelasOFFSIDES
378Erythema MultiformeCanada Vigilance: 1Canada Vigilance
SIDER
379Erythema Nodosum11579653CTD
380Fatty Liver288341
6933930
16545483
CTD
381Febrile NeutropeniaOFFSIDES
382Febrile bone marrow aplasiaOFFSIDES
383Fever

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CTD
384FlatulenceCanada Vigilance: 1Canada Vigilance
SIDER
385Gastrointestinal Diseases20497752CTD
386Glomerulonephritis

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CTD
387Glycosuria, Renal946666CTD
388Glycosuria990786CTD
389Graft dysfunctionOFFSIDES
390Gram-Positive Bacterial Infections8257125
16584310
CTD
391Granulomatous liver diseaseOFFSIDES
392GranulomaOFFSIDES
393Heart Diseases6626733CTD
394HeartburnSIDER
395Hematoma, Subdural, Acute19960218CTD
396Hematuria20497752CTD
397Hemoptysis13677879CTD
398Hepatic Insufficiency7402379CTD
399Hepatic congestionOFFSIDES
400Hepatitis B positiveOFFSIDES
401HiccoughOFFSIDES
402Hypercalcemia3663501
9767873
CTD
403Hyperglycemia23588309CTD
404Hyperthyroidism16236685CTD
405HypervitaminosisOFFSIDES
406Immunosuppressant drug level decreasedOFFSIDES
407ImmunosuppressionSIDER
408Impaired gastric emptyingOFFSIDES
409IncontinenceOFFSIDES
410Infection in an immunocompromised hostOFFSIDES
411InfestationSIDER
412Inflammation19487938CTD
413InfluenzaSIDER
414Intestinal ulcer perforationOFFSIDES
415Jaundice, Obstructive2488482CTD
416Joint prosthesis userOFFSIDES
417Kidney Diseases19761811CTD
418Kidney Papillary Necrosis3476051CTD
419Leprosy, Lepromatous

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CTD
420Leprosy, Multibacillary20140364CTD
421Leprosy

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CTD
422LeukoencephalopathyOFFSIDES
423Leukopenia neonatalOFFSIDES
424Liver Failure, Acute

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CTD
425Liver Failure76779
11316203
23764483
CTD
426Liver diseases

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CTD
427Liver neoplasms28108177CTD
428Loose toothOFFSIDES
429Lupus Erythematosus, Cutaneous11422169CTD
430Lupus Erythematosus, Systemic11422169CTD
431Lupus Nephritis10534557CTD
432Lysozyme increasedOFFSIDES
433Massive Hepatic Necrosis21224054CTD
434Meningitis, Bacterial

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CTD
435Meningitis, Pneumococcal7870156
8309909
9157169
CTD
436Meningitis18380704CTD
437Meningococcal Infections4980025
6798128
CTD
438Menstruation Disturbances1124382CTD
439Mental RetardationOFFSIDES
440Metabolic Side Effects of Drugs and Substances25070100CTD
441MetrorrhagiaSIDER
442Muscle FatigueOFFSIDES
443Muscle Weakness6789927CTD
444Muscle necrosisOFFSIDES
445Muscular Atrophy6789927CTD
446Mycobacterium Infections, Nontuberculous1949931
9546693
CTD
447Mycobacterium Infections3165976
18474467
CTD
448Mycobacterium chelonei infectionOFFSIDES
449Mycobacterium marinum InfectionOFFSIDES
450MyofascitisOFFSIDES
451MyopathySIDER
452Necrosis21419764CTD
SIDER
453Nephritis, Interstitial

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CTD
454Nodule on extremityOFFSIDES
455Numbness generalizedSIDER
456NumbnessSIDER
457Ocular HypertensionOFFSIDES
458Oligospermia20305954CTD
459Oliguria76779CTD
460Optic NeuritisOFFSIDES
461Osteomyelitis15843291CTD
OFFSIDES
462PachymeningitisOFFSIDES
463ParaplegiaOFFSIDES
464Paresthesia673833CTD
465Pemphigoid reactionSIDER
466Pericardial effusionOFFSIDES
467PericarditisOFFSIDES
468Pneumococcal Infections1495831
17079237
19487938
CTD
469PneumothoraxCanada Vigilance: 1Canada Vigilance
470Porphyria Cutanea Tarda6452153CTD
471Portal HypertensionOFFSIDES
472Primary sequestrumOFFSIDES
473Prostate examination abnormalOFFSIDES
474Pseudomonal sepsisOFFSIDES
475Pseudomonas Infections7645562CTD
476Reaction gastrointestinalSIDER
477Renal Insufficiency

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CTD
478Renal tubular acidosisOFFSIDES
479Renal tubular disorderOFFSIDES
480Respiratory Tract Infections1949931CTD
481RhinorrheaOFFSIDES
482Right Ventricular DysfunctionOFFSIDES
483SequestrectomyOFFSIDES
484Sore mouthSIDER
485Splenic InfarctionOFFSIDES
486SpondylitisOFFSIDES
487Sputum culture positiveOFFSIDES
488Staphylococcal Infections

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CTD
489Staphylococcal abscessOFFSIDES
490Subcutaneous AbscessOFFSIDES
491Substance Withdrawal Syndrome1256526
3960168
10653222
CTD
492Supraventricular tachycardiaOFFSIDES
493TendinitisOFFSIDES
494ThrombectomyOFFSIDES
495Thrombosis in deviceOFFSIDES
496TonsillitisOFFSIDES
497Tooth LossOFFSIDES
498Tuberculosis, Central Nervous System6709824CTD
499Tuberculosis, Gastrointestinal10534557CTD
500Tuberculosis, Meningeal7337308
10962632
CTD
501Tuberculosis, Multidrug-Resistant1096388
23764483
CTD
502Tuberculosis, Pulmonary

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CTD
503Tuberculosis, Renal3476051CTD
504Tuberculosis, Spinal16212643CTD
505TuberculosisCanada Vigilance: 1

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CTD
Canada Vigilance
506Ulcer24101390CTD
507Uremia129898
6472533
CTD
508Ureteral necrosisOFFSIDES
509Urethritis6619694CTD
510Vanishing bile duct syndromeOFFSIDES
511Vasculitis, Leukocytoclastic, Cutaneous2736984CTD
512Vasculitis1493242CTD
SIDER
513Venous Thrombosis2569610CTD
514anaphylaxis10066642CTD
515nervous system disorderSIDER
516pseudomembranous colitisSIDER
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