MetaADEDB 2.0 @ LMMD
Oxazepam
(ADIMAYPTOBDMTL-UHFFFAOYSA-N)
Structure
SMILES
O=C1Nc2ccc(cc2C(=NC1O)c1ccccc1)Cl
Type(s)
Approved
ATC code(s)
N05BA04
Molecular Formula:
C15H11ClN2O2
Molecular Weight:
286.713
Log P:
2.0215
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
61.69
CAS Number(s):
604-75-1
Synonym(s)
1.
Oxazepam
2.
Adumbran
3.
Serax
4.
Tazepam
External Link(s)
MeSHD010076
PubChem Compound4616
BindingDB85031
ChEBI7823
CHEMBLCHEMBL568
DrugBankDB00842
DrugCentral2015
IUPHAR/BPS Guide to PHARMACOLOGY7253
KEGGdr:D00464
cpd:C07359
Therapeutic Target DatabaseD09LDR
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DizzinessFAERS: 4
Canada Vigilance: 4		Canada Vigilance
OFFSIDES
SIDER
US FAERS
2Drug DependenceFAERS: 4
Canada Vigilance: 5		Canada Vigilance
US FAERS
3Drug ineffectiveFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
4Inappropriate schedule of drug administrationFAERS: 4US FAERS
5Intentional drug misuseFAERS: 4OFFSIDES
US FAERS
6Eye painFAERS: 3US FAERS
7NauseaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
8Product quality issueFAERS: 3US FAERS
9TensionFAERS: 3US FAERS
10Accidental overdoseFAERS: 2OFFSIDES
US FAERS
11AstheniaFAERS: 2US FAERS
12Blood glucose abnormalFAERS: 2US FAERS
13Depressed Level of ConsciousnessFAERS: 2SIDER
US FAERS
14Drug abuserFAERS: 2US FAERS
15Drug exposure during pregnancyFAERS: 2US FAERS
16Feeling ColdFAERS: 2US FAERS
17HeadacheFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
18MalaiseFAERS: 2US FAERS
19PainFAERS: 2US FAERS
20Pharmaceutical product complaintFAERS: 2US FAERS
21Product substitution issueFAERS: 2US FAERS
22Product use in unapproved indicationFAERS: 2US FAERS
23Toxicity to various agentsFAERS: 2US FAERS
24TremorFAERS: 2SIDER
US FAERS
25Unevaluable eventFAERS: 2US FAERS
26UrticariaFAERS: 2
Canada Vigilance: 2		Canada Vigilance
US FAERS
27Wrong drug administeredFAERS: 2US FAERS
28Accidental drug intake by childFAERS: 1US FAERS
29AgitationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
30Alanine Aminotransferase IncreasedFAERS: 1US FAERS
31AnxietyFAERS: 1US FAERS
32Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
33Burning sensationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
34Carbon dioxide abnormalFAERS: 1US FAERS
35Chest discomfortFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
36ChokingFAERS: 1US FAERS
37Completed SuicideFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
38DeafnessFAERS: 1US FAERS
39Death of relativeFAERS: 1US FAERS
40DependenceFAERS: 1US FAERS
41DisorientationFAERS: 1SIDER
US FAERS
42Drug effect incompleteFAERS: 1US FAERS
43Drug withdrawal syndromeFAERS: 1US FAERS
44DysarthriaFAERS: 1SIDER
US FAERS
45Electrocardiogram changeFAERS: 1US FAERS
46FatigueFAERS: 111488371
16182353		CTD
US FAERS
47Feeling abnormalFAERS: 1US FAERS
48Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
49HypersensitivityFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
50Impaired work abilityFAERS: 1US FAERS
51Incorrect route of drug administrationFAERS: 1OFFSIDES
US FAERS
52Increased bronchial secretionFAERS: 1US FAERS
53Lip swellingFAERS: 1US FAERS
54Memory impairmentFAERS: 1SIDER
US FAERS
55Mental impairmentFAERS: 1US FAERS
56Mouth swellingFAERS: 1US FAERS
57OverdoseFAERS: 1OFFSIDES
US FAERS
58PalpitationsFAERS: 1US FAERS
59Product physical issueFAERS: 1US FAERS
60PruritusFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
61Respiratory FailureFAERS: 1US FAERS
62ScreamingFAERS: 1US FAERS
63ShockFAERS: 1SIDER
US FAERS
64TachycardiaFAERS: 1US FAERS
65Throat irritationFAERS: 1US FAERS
66VertigoFAERS: 1SIDER
US FAERS
67Visual ImpairmentFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
68VomitingFAERS: 1US FAERS
69Abdominal PainSIDER
70AcidosisOFFSIDES
71AdenocarcinomaOFFSIDES
72Adenoma9538042CTD
73AgranulocytosisSIDER
74AgraphiaOFFSIDES
75Akathisia, Drug-Induced11488371CTD
76AkinesiaOFFSIDES
77Allergy test positiveOFFSIDES
78AmnesiaCanada Vigilance: 1Canada Vigilance
SIDER
79Amyloidosis7982536CTD
80Anti-neutrophil cytoplasmic antibody positive vasculitisOFFSIDES
81Anxiety Disorders7769598
7885422
8293377		CTD
82AphoniaOFFSIDES
83ApneaOFFSIDES
84AscitesOFFSIDES
85AtaxiaOFFSIDES
SIDER
86AuraOFFSIDES
87Bilirubin conjugated increasedOFFSIDES
88BlepharospasmOFFSIDES
89Blood creatinine increasedOFFSIDES
90Blood glucose decreasedOFFSIDES
91Blood osmolarity decreasedOFFSIDES
92Blood phosphorus increasedOFFSIDES
93Blood sodiumOFFSIDES
94Body TemperatureOFFSIDES
95Bowel movement irregularityOFFSIDES
96BruxismOFFSIDES
97BursitisOFFSIDES
98Cardiac ArrestCanada Vigilance: 1Canada Vigilance
99Cardiac TamponadeOFFSIDES
100Cardiac valve vegetationOFFSIDES
101Cataract operationOFFSIDES
102CatatoniaOFFSIDES
103Cerebral disorderOFFSIDES
104Chemotherapeutic drug level increasedOFFSIDES
105CholangiolitisOFFSIDES
106Cholestatic liver injuryOFFSIDES
107Chronic left ventricular failureOFFSIDES
108CirrhosisOFFSIDES
109Cocaine-Related Disorders18692521CTD
110Concomitant disease aggravatedOFFSIDES
111ConfabulationOFFSIDES
112Congenital tricuspid valve incompetenceOFFSIDES
113Consciousness fluctuatingOFFSIDES
114ConstipationCanada Vigilance: 1Canada Vigilance
115Conversion disorderOFFSIDES
116Coombs test negativeOFFSIDES
117Coronary Thrombosis16048847CTD
118Creatinine urine decreasedOFFSIDES
119Crush syndromeOFFSIDES
120Cytolytic hepatitisOFFSIDES
121Deafness NeurosensoryOFFSIDES
122DermatitisSIDER
123DiarrheaOFFSIDES
124DiplopiaCanada Vigilance: 1Canada Vigilance
SIDER
125Disseminated Intravascular CoagulationOFFSIDES
126DrowsinessOFFSIDES
SIDER
127Drug level changedOFFSIDES
128Drug level increasedCanada Vigilance: 1Canada Vigilance
129Drug toxicityOFFSIDES
130Dysthymic DisorderOFFSIDES
131Electroencephalogram abnormalCanada Vigilance: 1Canada Vigilance
132Embolic strokeOFFSIDES
133EmbolismOFFSIDES
134Empty Sella SyndromeOFFSIDES
135EmpyemaOFFSIDES
136EndocarditisOFFSIDES
137EpilepsyOFFSIDES
138ErysipelasOFFSIDES
139Escherichia infectionOFFSIDES
140Euphoric moodSIDER
141Facial NeuralgiaOFFSIDES
142Fanconi SyndromeOFFSIDES
143Febrile NeutropeniaOFFSIDES
144Fixed drug eruptionSIDER
145Flank PainOFFSIDES
146FlatulenceCanada Vigilance: 1Canada Vigilance
147Fluid overloadOFFSIDES
148FormicationOFFSIDES
149Gastrointestinal PainSIDER
150General physical health deteriorationOFFSIDES
151Genital erosionOFFSIDES
152GoiterOFFSIDES
153Growth Disorders3936103CTD
154Hepatoblastoma7982536CTD
155Hepatomegaly3698206
9538042		CTD
156Hyperplasia7982536
9538042		CTD
157Hypertrophy12727805CTD
158HyperventilationCanada Vigilance: 1Canada Vigilance
OFFSIDES
159HypokinesiaOFFSIDES
160HypotensionCanada Vigilance: 1Canada Vigilance
SIDER
161Iliac artery occlusionOFFSIDES
162IncontinenceSIDER
163InfectionOFFSIDES
164Intention tremorOFFSIDES
165Kidney FailureOFFSIDES
166LethargyCanada Vigilance: 1Canada Vigilance
SIDER
167LeukoaraiosisOFFSIDES
168LeukoencephalopathyOFFSIDES
169LeukopeniaSIDER
170Lip erosionOFFSIDES
171LipaseOFFSIDES
172Liver Neoplasms, Experimental

View details

3698206
7982536
8200073
12727805
 		CTD
173Liver neoplasms10467420CTD
174Liver transplant rejectionOFFSIDES
175Locked-In SyndromeOFFSIDES
176Malignant tumour excisionOFFSIDES
177Medication ErrorCanada Vigilance: 1Canada Vigilance
178MedulloblastomaOFFSIDES
179Mucosal erosionOFFSIDES
180Multiple drug overdoseOFFSIDES
181Muscle strainOFFSIDES
182Musculoskeletal stiffnessCanada Vigilance: 1Canada Vigilance
183Myocardial ruptureOFFSIDES
184Myoclonic EpilepsyOFFSIDES
185Narcotic intoxicationOFFSIDES
186Nasal mucosal disorderOFFSIDES
187Neurobehavioral Manifestations1646381CTD
188Neuroleptic Malignant SyndromeOFFSIDES
189Neutrophil count decreasedOFFSIDES
190Nipple painOFFSIDES
191NystagmusOFFSIDES
192Obesity surgeryOFFSIDES
193Oral fungal infectionOFFSIDES
194OsteoporosisOFFSIDES
195Panic Disorder6871816CTD
OFFSIDES
196Pericardial effusionOFFSIDES
197PericarditisOFFSIDES
198PneumothoraxOFFSIDES
199Poor quality sleepCanada Vigilance: 1Canada Vigilance
200Portal HypertensionOFFSIDES
201Pre-Eclampsia73027CTD
202Prenatal Exposure Delayed Effects1646381
3936103		CTD
203PresbyopiaOFFSIDES
204Psychotic Disorders12547310
14670884		CTD
205Renal tubular disorderOFFSIDES
206Restless Legs SyndromeCanada Vigilance: 1Canada Vigilance
207Retinal artery embolismOFFSIDES
208RhabdomyolysisOFFSIDES
209Seizures6774348CTD
210Septic ShockOFFSIDES
211Sinus bradycardiaOFFSIDES
212Skin neoplasm excisionOFFSIDES
213Slurred speechSIDER
214Somnambulism453369CTD
215SomnolenceCanada Vigilance: 5Canada Vigilance
SIDER
216Stevens-Johnson SyndromeOFFSIDES
217StuporCanada Vigilance: 1Canada Vigilance
SIDER
218SubileusOFFSIDES
219Substance Withdrawal Syndrome

View details

3365642
6418370
6806585
6810073
6871816
7132871
7573789
12296498
 		CTD
220Sudden deathOFFSIDES
221SyncopeCanada Vigilance: 1Canada Vigilance
SIDER
222Therapeutic response delayedCanada Vigilance: 1Canada Vigilance
223Transaminases increasedOFFSIDES
224Transfusion ReactionOFFSIDES
225Troponin increasedOFFSIDES
226Vitamin A DeficiencyOFFSIDES
227Vulvovaginal pruritusOFFSIDES
228Zinc deficiencyOFFSIDES
229jaundiceCanada Vigilance: 1Canada Vigilance
SIDER
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