MetaADEDB 2.0 @ LMMD
Aztreonam
(WZPBZJONDBGPKJ-VEHQQRBSSA-N)
Structure
SMILES
C[C@H]1[C@H](NC(=O)/C(=N\OC(C(=O)O)(C)C)/c2csc(n2)N)C(=O)N1S(=O)(=O)O
Type(s)
Approved
ATC code(s)
J01DF01
Molecular Formula:
C13H17N5O8S2
Molecular Weight:
435.433
Log P:
0.8183
Hydrogen Bond Acceptor:
14
Hydrogen Bond Donor:
4
TPSA:
238.2
CAS Number(s):
78110-38-0; 149496-40-2
Synonym(s)
1.
Aztreonam
2.
Az-threonam
3.
Azactam
4.
Azthreonam
5.
SQ-26,776
6.
Urobactam
7.
Az threonam
8.
SQ 26,776
9.
SQ26,776
External Link(s)
MeSHD001398
PubChem Compound135398736
5742832
9568617
BindingDB50240480
ChEBI161680
CHEMBLCHEMBL158
DrugBankDB00355
DrugCentral279
KEGGcpd:C06840
dr:D00240
Therapeutic Target DatabaseD0F2XV
ZINC12503091
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Respiratory FailureFAERS: 55OFFSIDES
US FAERS
2Cystic FibrosisFAERS: 33
Canada Vigilance: 2		19747007CTD
Canada Vigilance
US FAERS
3ArthralgiaFAERS: 31US FAERS
4LacerationFAERS: 25US FAERS
5Chest discomfortFAERS: 22SIDER
US FAERS
6HeadacheFAERS: 18SIDER
US FAERS
7Infective pulmonary exacerbation of cystic fibrosisFAERS: 17
Canada Vigilance: 2		Canada Vigilance
US FAERS
8Product package associated injuryFAERS: 17US FAERS
9VomitingFAERS: 16SIDER
US FAERS
10FatigueFAERS: 15US FAERS
11PneumoniaFAERS: 15
Canada Vigilance: 2		Canada Vigilance
US FAERS
12Drug ineffectiveFAERS: 14US FAERS
13NauseaFAERS: 13SIDER
US FAERS
14Throat irritationFAERS: 12US FAERS
15MalaiseFAERS: 11
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
16Product container issueFAERS: 11US FAERS
17Unevaluable eventFAERS: 11OFFSIDES
US FAERS
18Oropharyngeal painFAERS: 10US FAERS
19Product closure removal difficultFAERS: 10US FAERS
20WheezingFAERS: 10SIDER
US FAERS
21AstheniaFAERS: 9SIDER
US FAERS
22SuperinfectionFAERS: 9US FAERS
23Joint swellingFAERS: 8SIDER
US FAERS
24Product storage errorFAERS: 8US FAERS
25Feeling abnormalFAERS: 7SIDER
US FAERS
26HypersensitivityFAERS: 7SIDER
US FAERS
27NasopharyngitisFAERS: 7OFFSIDES
US FAERS
28Pulmonary function test decreasedFAERS: 7
Canada Vigilance: 1		Canada Vigilance
US FAERS
29SepsisFAERS: 7US FAERS
30UrticariaFAERS: 711792017CTD
SIDER
US FAERS
31BronchiectasisFAERS: 6OFFSIDES
US FAERS
32BronchitisFAERS: 6
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
33Drug dose omissionFAERS: 6US FAERS
34InfluenzaFAERS: 6US FAERS
35Maternal exposure during pregnancyFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
36PainFAERS: 6OFFSIDES
SIDER
US FAERS
37Chest PainFAERS: 5SIDER
US FAERS
38Intentional dose omissionFAERS: 5US FAERS
39Medication ErrorFAERS: 5US FAERS
40Productive CoughFAERS: 5US FAERS
41PruritusFAERS: 5SIDER
US FAERS
42SinusitisFAERS: 5US FAERS
43Abdominal discomfortFAERS: 4US FAERS
44Bone painFAERS: 4OFFSIDES
US FAERS
45BronchospasmFAERS: 4SIDER
US FAERS
46ChillsFAERS: 4US FAERS
47Circumstance or information capable of leading to medication errorFAERS: 4US FAERS
48DysphoniaFAERS: 4US FAERS
49FlushingFAERS: 4SIDER
US FAERS
50Intentional product use issueFAERS: 4US FAERS
51Mood swingsFAERS: 4US FAERS
52MyalgiaFAERS: 4SIDER
US FAERS
53Acute respiratory failureFAERS: 3US FAERS
54AnxietyFAERS: 3OFFSIDES
US FAERS
55DiplopiaFAERS: 3SIDER
US FAERS
56DizzinessFAERS: 3SIDER
US FAERS
57EosinophiliaFAERS: 32967033CTD
SIDER
US FAERS
58General physical health deteriorationFAERS: 3OFFSIDES
US FAERS
59HypoxiaFAERS: 3OFFSIDES
US FAERS
60Intestinal ObstructionFAERS: 3
Canada Vigilance: 2		Canada Vigilance
US FAERS
61LethargyFAERS: 3US FAERS
62Lip swellingFAERS: 3US FAERS
63Product dose omissionFAERS: 3
Canada Vigilance: 3		Canada Vigilance
US FAERS
64Product packaging issueFAERS: 3US FAERS
65Stevens-Johnson SyndromeFAERS: 325811541CTD
OFFSIDES
US FAERS
66SwellingFAERS: 3SIDER
US FAERS
67TinnitusFAERS: 3SIDER
US FAERS
68Toxic Epidermal NecrolysisFAERS: 3SIDER
US FAERS
69White blood cell count decreasedFAERS: 3US FAERS
70Wrong device usedFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
71pseudomembranous colitisFAERS: 3SIDER
US FAERS
72Abdominal PainFAERS: 2OFFSIDES
SIDER
US FAERS
73AlopeciaFAERS: 2OFFSIDES
US FAERS
74Anaphylactic shockFAERS: 2SIDER
US FAERS
75Application site erythemaFAERS: 2US FAERS
76Application site swellingFAERS: 2US FAERS
77Burning sensationFAERS: 2US FAERS
78Cardiac FlutterFAERS: 2US FAERS
79Coombs test positiveFAERS: 2SIDER
US FAERS
80CystitisFAERS: 2US FAERS
81Dental cariesFAERS: 2OFFSIDES
US FAERS
82DiscomfortFAERS: 2SIDER
US FAERS
83Enamel anomalyFAERS: 2US FAERS
84EpistaxisFAERS: 2US FAERS
85Erythema NodosumFAERS: 2US FAERS
86ErythemaFAERS: 2SIDER
US FAERS
87Expired drug administeredFAERS: 2US FAERS
88Hearing disabilityFAERS: 2US FAERS
89Incorrect route of drug administrationFAERS: 2US FAERS
90Musculoskeletal discomfortFAERS: 2SIDER
US FAERS
91Nail InfectionFAERS: 2US FAERS
92Pleuritic painFAERS: 2US FAERS
93Product physical issueFAERS: 2US FAERS
94Product preparation errorFAERS: 2US FAERS
95Product use issueFAERS: 2US FAERS
96Pseudomonal sepsisFAERS: 2US FAERS
97Pulmonary congestionFAERS: 2OFFSIDES
US FAERS
98Rash erythematousFAERS: 2US FAERS
99Respiratory tract irritationFAERS: 2US FAERS
100Septic ShockFAERS: 2OFFSIDES
US FAERS
101ShockFAERS: 2US FAERS
102SomnolenceFAERS: 2US FAERS
103StomatitisFAERS: 2SIDER
US FAERS
104Therapy cessationFAERS: 2US FAERS
105ThrombocytopeniaFAERS: 2SIDER
US FAERS
106Upper respiratory tract congestionFAERS: 2US FAERS
107VertigoFAERS: 2SIDER
US FAERS
108Wrong technique in drug usage processFAERS: 2US FAERS
109AgeusiaFAERS: 1US FAERS
110AgranulocytosisFAERS: 1US FAERS
111Alcohol abuseFAERS: 1US FAERS
112AmnesiaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
113AngioedemaFAERS: 1SIDER
US FAERS
114AsthmaFAERS: 1US FAERS
115Ataxia TelangiectasiaFAERS: 1US FAERS
116Bacterial sepsisFAERS: 1US FAERS
117Bronchial HyperreactivityFAERS: 1US FAERS
118Bronchial ObstructionFAERS: 1US FAERS
119BronchiolitisFAERS: 1US FAERS
120BronchopneumoniaFAERS: 1US FAERS
121Cervix carcinomaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
122CholangitisFAERS: 1US FAERS
123Chronic respiratory failureFAERS: 1US FAERS
124Cold sweatFAERS: 1OFFSIDES
US FAERS
125Deep Vein ThrombosisFAERS: 1US FAERS
126Device connection issueFAERS: 1US FAERS
127Device malfunctionFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
128Drug administered in wrong deviceFAERS: 1US FAERS
129DysgeusiaFAERS: 1SIDER
US FAERS
130EndocarditisFAERS: 1US FAERS
131Enterococcal infectionFAERS: 1OFFSIDES
US FAERS
132Expired product administeredFAERS: 1US FAERS
133Eyelids pruritusFAERS: 1US FAERS
134Failure to ThriveFAERS: 1US FAERS
135FlatulenceFAERS: 1US FAERS
136HypotensionFAERS: 1SIDER
US FAERS
137Impaired self-careFAERS: 1US FAERS
138Incorrect dose administeredFAERS: 1US FAERS
139Incorrect product formulation administeredFAERS: 1US FAERS
140Incorrect storage of drugFAERS: 1US FAERS
141Increased upper airway secretionFAERS: 1US FAERS
142Increased viscosity of bronchial secretionFAERS: 1US FAERS
143InfectionFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
144Infective exacerbation of bronchiectasisFAERS: 1US FAERS
145Injection site extravasationFAERS: 1US FAERS
146Intentional device misuseFAERS: 1US FAERS
147Intentional product misuseFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
148Limb injuryFAERS: 1US FAERS
149Liquid product physical issueFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
150Lung AbscessFAERS: 1OFFSIDES
US FAERS
151MalnutritionFAERS: 1US FAERS
152Mechanical ventilationFAERS: 1US FAERS
153Memory impairmentFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
154Nasal discomfortFAERS: 1US FAERS
155NeutropeniaFAERS: 1SIDER
US FAERS
156Oral mucosal eruptionFAERS: 1US FAERS
157OsteomyelitisFAERS: 1US FAERS
158OverdoseFAERS: 1US FAERS
159PallorFAERS: 1OFFSIDES
US FAERS
160Pathogen resistanceFAERS: 1US FAERS
161PetechiaeFAERS: 1SIDER
US FAERS
162Pneumonia Pseudomonas aeruginosaFAERS: 1US FAERS
163Portal HypertensionFAERS: 1US FAERS
164PregnancyFAERS: 1US FAERS
165Product container seal issueFAERS: 1US FAERS
166Product contamination physicalFAERS: 1US FAERS
167Product packaging quantity issueFAERS: 1US FAERS
168Product taste abnormalFAERS: 1US FAERS
169Product use complaintFAERS: 1US FAERS
170Pulmonary EmbolismFAERS: 1US FAERS
171Rhinovirus infectionFAERS: 1US FAERS
172Sinus operationFAERS: 1US FAERS
173Skin lacerationFAERS: 1US FAERS
174Stoma site dischargeFAERS: 1US FAERS
175Stoma site irritationFAERS: 1US FAERS
176SyncopeFAERS: 1US FAERS
177Therapy changeFAERS: 1US FAERS
178Urinary tract infectionFAERS: 1US FAERS
179Visual ImpairmentFAERS: 1US FAERS
180Weight decreasedFAERS: 1US FAERS
181nervous system disorderFAERS: 1US FAERS
182treatment failureFAERS: 1US FAERS
183Abdominal CrampsSIDER
184Abdominal InfectionOFFSIDES
185Abnormal visionOFFSIDES
186Abscess18319500CTD
OFFSIDES
187AbuliaOFFSIDES
188AcheSIDER
189AcidosisOFFSIDES
190Acute kidney injury2967033CTD
191Acute sinusitisOFFSIDES
192Alanine Aminotransferase IncreasedOFFSIDES
SIDER
193Alanine aminotransferase abnormalOFFSIDES
194AnhedoniaOFFSIDES
195AnorexiaOFFSIDES
196Anoxic EncephalopathyOFFSIDES
197Antithrombin III DeficiencyOFFSIDES
198Aortic InjuryOFFSIDES
199ApneaOFFSIDES
200AscitesOFFSIDES
201Aspartate Aminotransferase IncreasedSIDER
202Aspartate aminotransferase abnormalOFFSIDES
203AtaxiaOFFSIDES
204Atrial tachycardiaOFFSIDES
205BedriddenOFFSIDES
206Blood GlucoseOFFSIDES
207Blood alkaline phosphatase increasedOFFSIDES
208Blood bilirubin abnormalOFFSIDES
209Blood chloride increasedOFFSIDES
210Blood cholesterolOFFSIDES
211Blood cortisol increasedOFFSIDES
212Blood creatine increasedOFFSIDES
213Blood creatinine increasedOFFSIDES
SIDER
214Blood glucose abnormalOFFSIDES
215Blood phosphorus decreasedOFFSIDES
216Blood potassium increasedOFFSIDES
217Blood sodium increasedOFFSIDES
218Blood sodiumOFFSIDES
219Blood urea increasedOFFSIDES
220Blunted affectOFFSIDES
221Body TemperatureOFFSIDES
222Bone lesionOFFSIDES
223Brain natriuretic peptide increasedOFFSIDES
224Breast tendernessSIDER
225Bronchial irritationOFFSIDES
226BursitisOFFSIDES
227Carnitine deficiencyOFFSIDES
228Cerebral hypoperfusionOFFSIDES
229Choking sensationOFFSIDES
230CholecystitisOFFSIDES
231Clostridium difficile toxin test positiveOFFSIDES
232Creatinine renal clearance decreasedOFFSIDES
233Crohn Disease18319500CTD
234Cytolytic hepatitisOFFSIDES
235DeafnessOFFSIDES
236DemyelinationOFFSIDES
237DermatitisSIDER
238Device interactionOFFSIDES
239Disease ProgressionOFFSIDES
240Disseminated Intravascular CoagulationOFFSIDES
241Drug Eruptions11792017CTD
242Drug withdrawal headacheOFFSIDES
243DuodenitisOFFSIDES
244Economic problemOFFSIDES
245Emotional disorderOFFSIDES
246Encephalitis3909319CTD
247Endodontic procedureOFFSIDES
248Erythema MultiformeSIDER
249Escherichia coli Infections3909335CTD
250Escherichia infectionOFFSIDES
251Exanthema2967033CTD
252Eye InfectionOFFSIDES
253Facial NeuralgiaOFFSIDES
254Febrile NeutropeniaOFFSIDES
255Fever2967033CTD
256Fluid overloadOFFSIDES
257Gastrointestinal PainSIDER
258Gingival HypertrophyOFFSIDES
259Graft versus host disease in lungOFFSIDES
260Gram-Negative Bacterial Infections3909319CTD
261Hepatitis B positiveOFFSIDES
262HepatitisSIDER
263HydrocephalusOFFSIDES
264HydronephrosisOFFSIDES
265Hypoaesthesia facialOFFSIDES
266Incision site complicationOFFSIDES
267Incision site erythemaOFFSIDES
268IndurationSIDER
269Intestinal PerforationOFFSIDES
270Joint sprainOFFSIDES
271Kidney FailureOFFSIDES
272LeukocytosisSIDER
273Leukopenia neonatalOFFSIDES
274Local reactionSIDER
275Loose toothOFFSIDES
276Lumbar radiculopathyOFFSIDES
277Lung herniaOFFSIDES
278Lung infection pseudomonalOFFSIDES
279Malignant neoplasm progressionOFFSIDES
280Mastication disorderOFFSIDES
281MediastinitisOFFSIDES
282Meningitis, Bacterial2068463CTD
283Meningitis3909319CTD
284Mental impairmentOFFSIDES
285Mental status changesOFFSIDES
286Mesenteric vascular insufficiencyOFFSIDES
287Metabolic acidosisOFFSIDES
288Mixed liver injuryOFFSIDES
289Musculoskeletal chest painOFFSIDES
290Neutropenic infectionOFFSIDES
291Neutrophil count decreasedOFFSIDES
292NoduleOFFSIDES
293OliguriaOFFSIDES
294PancytopeniaSIDER
295ParacentesisOFFSIDES
296PeriodontitisOFFSIDES
297Peritoneal DialysisOFFSIDES
298PeritonitisOFFSIDES
299Pharyngolaryngeal PainSIDER
300PhlebitisSIDER
301PlasmacytomaOFFSIDES
302PneumothoraxOFFSIDES
303Pseudomonas Infections3909335CTD
304Pulmonary HypertensionOFFSIDES
305PurpuraSIDER
306Refusal of treatment by relativeOFFSIDES
307Renal tubular necrosisOFFSIDES
308Retinal infarctionOFFSIDES
309ScabOFFSIDES
310ScotomaOFFSIDES
311Seizures7634817
8889722		CTD
312SequestrectomyOFFSIDES
313Serratia Infections3909335CTD
314Sinus headacheOFFSIDES
315Sinus polypOFFSIDES
316SneezingSIDER
317Soft Tissue InfectionOFFSIDES
318Soft tissue inflammationOFFSIDES
319Spinal column stenosisOFFSIDES
320Sputum culture positiveOFFSIDES
321Staphylococcal Infections7645562CTD
322Stem cell transplantOFFSIDES
323Stenotrophomonas infectionOFFSIDES
324Sudden deathOFFSIDES
325Synovial CystOFFSIDES
326ThrombocytosisSIDER
327ThrombophlebitisSIDER
328Tooth ExtractionOFFSIDES
329TracheobronchitisOFFSIDES
330Transaminases increasedOFFSIDES
331Trichosporon infectionOFFSIDES
332Vaginal cellulitisOFFSIDES
333Vascular calcificationOFFSIDES
334Vascular purpuraSIDER
335Ventricular FibrillationOFFSIDES
336Ventricular bigeminySIDER
337Vocal Cord ParalysisOFFSIDES
338Vulvovaginal mycotic infectionSIDER
339Walking aid userOFFSIDES
340Wound ComplicationOFFSIDES
341jaundiceSIDER
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