MetaADEDB 2.0 @ LMMD
calcipotriene
(LWQQLNNNIPYSNX-UROSTWAQSA-N)
Structure
SMILES
O[C@H]1C[C@H](O)C(=C)/C(=C\C=C\2/CCC[C@]3([C@H]2CC[C@@H]3[C@@H](/C=C/[C@H](C2CC2)O)C)C)/C1
Type(s)
Approved
ATC code(s)
D05AX02; D05AX52
Molecular Formula:
C27H40O3
Molecular Weight:
412.605
Log P:
5.0906
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
3
TPSA:
60.69
CAS Number(s):
112828-00-9; 112965-21-6
Synonym(s)
1.
calcipotriene
2.
1,24(OH)2-22-ene-24-cyclopropyl D3
3.
Daivonex
4.
Dovonex
5.
Enstilar
6.
MC 903
7.
MC-903
8.
PRI-2205
9.
Psorcutan
10.
Sorilux
11.
calcipotriol
12.
heximar win care
External Link(s)
MeSHC055085
PubChem Compound5288783
BindingDB50369964
ChEBI50749
CHEMBLCHEMBL1200666
DrugBankDB02300
DrugCentral465
IUPHAR/BPS Guide to PHARMACOLOGY2778
KEGGdr:D01125
Therapeutic Target DatabaseD01QUS
ZINC3921872
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 14OFFSIDES
US FAERS
2PsoriasisFAERS: 10

View details

8011511
8490416
8609254
8620449
9344189
12196891
14999528
18173537
21228817
24039193
24046278
 		CTD
OFFSIDES
US FAERS
3ErythemaFAERS: 8
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
4PruritusFAERS: 7SIDER
US FAERS
5Burning sensationFAERS: 5OFFSIDES
US FAERS
6Drug administered at inappropriate siteFAERS: 4OFFSIDES
US FAERS
7Application site painFAERS: 3SIDER
US FAERS
8EczemaFAERS: 3OFFSIDES
US FAERS
9EndophthalmitisFAERS: 3OFFSIDES
US FAERS
10Medication ErrorFAERS: 3US FAERS
11NephrolithiasisFAERS: 3OFFSIDES
US FAERS
12Skin irritationFAERS: 3SIDER
US FAERS
13Abdominal discomfortFAERS: 2OFFSIDES
US FAERS
14Angina PectorisFAERS: 2US FAERS
15Application site erythemaFAERS: 2OFFSIDES
SIDER
US FAERS
16Application site reactionFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
17AstheniaFAERS: 2OFFSIDES
US FAERS
18ConstipationFAERS: 2US FAERS
19Crystal urine presentFAERS: 2US FAERS
20Drug screen positiveFAERS: 2US FAERS
21Dry skinFAERS: 2OFFSIDES
SIDER
US FAERS
22Emotional distressFAERS: 2US FAERS
23Eye irritationFAERS: 2US FAERS
24FatigueFAERS: 2OFFSIDES
US FAERS
25HyperkeratosisFAERS: 2OFFSIDES
US FAERS
26Incorrect drug administration durationFAERS: 2US FAERS
27InflammationFAERS: 2US FAERS
28Leukocytoclastic vasculitisFAERS: 2US FAERS
29MalaiseFAERS: 2US FAERS
30OsteoporosisFAERS: 2US FAERS
31OverdoseFAERS: 2US FAERS
32PainFAERS: 2OFFSIDES
SIDER
US FAERS
33PregnancyFAERS: 2US FAERS
34Product prescribing issueFAERS: 2US FAERS
35Product use in unapproved indicationFAERS: 2US FAERS
36Rash erythematousFAERS: 2US FAERS
37Skin lesionFAERS: 2US FAERS
38Abdominal PainFAERS: 1US FAERS
39Accidental drug intake by childFAERS: 1US FAERS
40Application site alopeciaFAERS: 1US FAERS
41Application site exfoliationFAERS: 1US FAERS
42Application site irritationFAERS: 1US FAERS
43Application site vesiclesFAERS: 1US FAERS
44ArthralgiaFAERS: 1US FAERS
45Atrial FibrillationFAERS: 1US FAERS
46Blood cholesterol increasedFAERS: 1US FAERS
47Blood triglycerides increasedFAERS: 1OFFSIDES
US FAERS
48Cerebrovascular accidentFAERS: 1US FAERS
49DermatitisFAERS: 1SIDER
US FAERS
50Device use errorFAERS: 1US FAERS
51DiscomfortFAERS: 1US FAERS
52Disease recurrenceFAERS: 1US FAERS
53Drug dose omissionFAERS: 1US FAERS
54Drug exposure during pregnancyFAERS: 1US FAERS
55Drug ineffective for unapproved indicationFAERS: 1US FAERS
56DysgeusiaFAERS: 1OFFSIDES
US FAERS
57DystoniaFAERS: 1US FAERS
58EpilepsyFAERS: 1US FAERS
59Feeling abnormalFAERS: 1US FAERS
60General physical health deteriorationFAERS: 1US FAERS
61GoutFAERS: 1US FAERS
62HeadacheFAERS: 1US FAERS
63HypersensitivityFAERS: 1SIDER
US FAERS
64HypospadiasFAERS: 1US FAERS
65Hypothalamo-pituitary disorderFAERS: 1US FAERS
66Inappropriate schedule of drug administrationFAERS: 1US FAERS
67Incorrect dose administeredFAERS: 1US FAERS
68MacrocytosisFAERS: 1US FAERS
69Medication residueFAERS: 1OFFSIDES
US FAERS
70MicrolithiasisFAERS: 1US FAERS
71NauseaFAERS: 1US FAERS
72Pain of skinFAERS: 1US FAERS
73PallorFAERS: 1OFFSIDES
US FAERS
74Product quality issueFAERS: 1US FAERS
75Product substitution errorFAERS: 1US FAERS
76Product substitution issueFAERS: 1US FAERS
77Respiratory FailureFAERS: 1US FAERS
78Skin hypertrophyFAERS: 1OFFSIDES
US FAERS
79Skin reactionFAERS: 1US FAERS
80Therapeutic response delayedFAERS: 1US FAERS
81TinnitusFAERS: 1US FAERS
82UlcerFAERS: 1US FAERS
83UrticariaFAERS: 1US FAERS
84Ventricular FibrillationFAERS: 1US FAERS
85Violence-related symptomFAERS: 1US FAERS
86Abdominal rigidityOFFSIDES
87AgeusiaOFFSIDES
88Alanine Aminotransferase IncreasedOFFSIDES
89Alcohol poisoningOFFSIDES
90AngioedemaOFFSIDES
91AnhidrosisOFFSIDES
92Asymptomatic bacteriuriaOFFSIDES
93AtherosclerosisOFFSIDES
94Back disorderOFFSIDES
95Blood alkaline phosphatase abnormalOFFSIDES
96Blood alkaline phosphatase increasedOFFSIDES
97Blood cholesterolOFFSIDES
98Blood creatine increasedOFFSIDES
99Blood creatinine increasedOFFSIDES
100Blood immunoglobulin G increasedOFFSIDES
101Blood magnesium decreasedOFFSIDES
102Blood potassium increasedOFFSIDES
103Blood uric acidOFFSIDES
104Blurred visionOFFSIDES
105Brain natriuretic peptide increasedOFFSIDES
106BruxismOFFSIDES
107CD4 Lymphocytes DecreasedOFFSIDES
108Chest PainOFFSIDES
109Chronic Obstructive Airway DiseaseOFFSIDES
110Circumstance or information capable of leading to medication errorOFFSIDES
111Congenital tricuspid valve incompetenceOFFSIDES
112Conjunctival depositOFFSIDES
113Contact DermatitisOFFSIDES
114Culture positiveOFFSIDES
115DeafnessOFFSIDES
116Dermatitis, Atopic16880407
24046278		CTD
117DiabetesOFFSIDES
118DiarrheaOFFSIDES
119Drug withdrawal headacheOFFSIDES
120EnchondromatosisOFFSIDES
121Enterococcal infectionOFFSIDES
122Eosinophil percentage increasedOFFSIDES
123Epstein-Barr virus antibody positiveOFFSIDES
124Epstein-Barr virus test positiveOFFSIDES
125Erythema MultiformeOFFSIDES
126False positive laboratory resultOFFSIDES
127Fixed eruptionOFFSIDES
128FlatulenceOFFSIDES
129FolliculitisSIDER
130FormicationOFFSIDES
131General symptomOFFSIDES
132GlomerulonephritisOFFSIDES
133Guttate psoriasisOFFSIDES
134Hepatic necrosisOFFSIDES
135HomicideOFFSIDES
136Hypercalcemia

View details

8011511
8120527
8490416
14999528
18173537
 		CTD
137Hypernatremia14999528CTD
138HyperpigmentationOFFSIDES
139HyperventilationOFFSIDES
140Injection site erythemaOFFSIDES
141Injection site infectionOFFSIDES
142Injection site vesiclesOFFSIDES
143Instillation site painSIDER
144Joint Range of Motion DecreasedOFFSIDES
145Joint stiffnessCanada Vigilance: 1Canada Vigilance
146Joint swellingCanada Vigilance: 1Canada Vigilance
147Kidney FailureOFFSIDES
148LaryngospasmOFFSIDES
149Left Ventricular HypertrophyOFFSIDES
150Left ventricular end-diastolic pressure increasedOFFSIDES
151Live BirthOFFSIDES
152Lung infection pseudomonalOFFSIDES
153Lymphocyte stimulation test positiveOFFSIDES
154MicrocytosisOFFSIDES
155MononeuritisOFFSIDES
156Multiple SclerosisOFFSIDES
157Musculoskeletal PainOFFSIDES
158Musculoskeletal discomfortOFFSIDES
159Musculoskeletal stiffnessOFFSIDES
160Mycosis FungoidesOFFSIDES
161Nail bed infectionOFFSIDES
162NasopharyngitisOFFSIDES
163Nephrogenic Fibrosing DermopathyOFFSIDES
164NocturiaOFFSIDES
165Nodular regenerative hyperplasiaOFFSIDES
166Open woundOFFSIDES
167Optic Disc EdemaOFFSIDES
168OsteomyelitisOFFSIDES
169PCO2 decreasedOFFSIDES
170Penis carcinomaOFFSIDES
171PericarditisOFFSIDES
172PingueculaOFFSIDES
173Portal HypertensionOFFSIDES
174PouchitisOFFSIDES
175Procedural hypertensionOFFSIDES
176Pulmonary HypertensionOFFSIDES
177Purulent dischargeOFFSIDES
178Renal cystOFFSIDES
179Renal massOFFSIDES
180SclerodermaOFFSIDES
181Sebaceous hyperplasiaOFFSIDES
182SinusitisOFFSIDES
183Skin IndurationOFFSIDES
184Skin test positiveOFFSIDES
185Skin tightnessOFFSIDES
186Sputum culture positiveOFFSIDES
187Staphylococcal Scalded Skin SyndromeOFFSIDES
188StridorOFFSIDES
189Supraventricular tachycardiaOFFSIDES
190Therapy non-responderOFFSIDES
191Tooth InfectionOFFSIDES
192Tooth LossOFFSIDES
193Urethral StenosisOFFSIDES
194Urine leukocyte esteraseOFFSIDES
195Visual disturbanceOFFSIDES
196Weight GainOFFSIDES
197White blood cell count abnormalOFFSIDES
198effusionOFFSIDES
199keratoacanthomaOFFSIDES
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