MetaADEDB 2.0 @ LMMD
hydrocodone tartrate, ibuprofen drug combination
(OPEYVVLXBYHKDO-DANDVKJOSA-N)
Structure
SMILES
O[C@H]([C@H](C(=O)O)O)C(=O)O.CC(Cc1ccc(cc1)C(C(=O)O)C)C.COc1ccc2c3c1O[C@@H]1[C@@]43CCN([C@H](C2)[C@@H]4CCC1=O)C
Molecular Formula:
C35H45NO11
Molecular Weight:
655.732
Log P:
2.8218
Hydrogen Bond Acceptor:
12
Hydrogen Bond Donor:
5
TPSA:
191.13
CAS Number(s):
615580-69-3
Synonym(s)
1.
hydrocodone tartrate, ibuprofen drug combination
2.
Vicoprofen
3.
hydrocodone tartrate - ibuprofen
External Link(s)
MeSHC409362
PubChem Compound11445193
KEGGdr:D02152
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 14OFFSIDES
US FAERS
2PainFAERS: 5OFFSIDES
US FAERS
3Pharmaceutical product complaintFAERS: 5OFFSIDES
US FAERS
4DizzinessFAERS: 3OFFSIDES
US FAERS
5NauseaFAERS: 3OFFSIDES
US FAERS
6Drug DependenceFAERS: 2US FAERS
7Product quality issueFAERS: 2US FAERS
8VomitingFAERS: 2US FAERS
9AstheniaFAERS: 1OFFSIDES
US FAERS
10Back PainFAERS: 1US FAERS
11Blood cannabinoids increasedFAERS: 1US FAERS
12Completed SuicideFAERS: 1US FAERS
13DependenceFAERS: 1OFFSIDES
US FAERS
14Depressed moodFAERS: 1OFFSIDES
US FAERS
15Drug dispensing errorFAERS: 1US FAERS
16EpistaxisFAERS: 1OFFSIDES
US FAERS
17Feeling abnormalFAERS: 1US FAERS
18HepatomegalyFAERS: 1US FAERS
19Impaired quality of lifeFAERS: 1US FAERS
20Intestinal ObstructionFAERS: 1US FAERS
21MalaiseFAERS: 1US FAERS
22Medication ErrorFAERS: 1US FAERS
23Mental impairmentFAERS: 1OFFSIDES
US FAERS
24MyalgiaFAERS: 1US FAERS
25No adverse effectFAERS: 1US FAERS
26OverdoseFAERS: 1OFFSIDES
US FAERS
27Product packaging quantity issueFAERS: 1US FAERS
28PruritusFAERS: 1US FAERS
29Tablet physical issueFAERS: 1US FAERS
30Tongue blisteringFAERS: 1US FAERS
31TremorFAERS: 1US FAERS
32Unevaluable eventFAERS: 1OFFSIDES
US FAERS
33VertigoFAERS: 1US FAERS
34Wrong drug administeredFAERS: 1US FAERS
35Abdominal PainOFFSIDES
36Abdominal discomfortOFFSIDES
37Acid refluxOFFSIDES
38ActinomycosisOFFSIDES
39Acute bronchitisOFFSIDES
40Acute myocardial infarctionOFFSIDES
41AdenocarcinomaOFFSIDES
42Adrenal massOFFSIDES
43Adverse eventOFFSIDES
44AgoraphobiaOFFSIDES
45AgraphiaOFFSIDES
46Allergy to arthropod biteOFFSIDES
47Altered visual depth perceptionOFFSIDES
48AlveoloplastyOFFSIDES
49AnalgesiaOFFSIDES
50AngerOFFSIDES
51AnhedoniaOFFSIDES
52AnorexiaOFFSIDES
53Anoxic EncephalopathyOFFSIDES
54AnxietyOFFSIDES
55AphoniaOFFSIDES
56ArteriosclerosisOFFSIDES
57ArthritisOFFSIDES
58ArthropathyOFFSIDES
59Arthropod biteOFFSIDES
60Artificial crown procedureOFFSIDES
61AsthmaOFFSIDES
62AtaxiaOFFSIDES
63Atrial FlutterOFFSIDES
64AuraOFFSIDES
65Bacterial EndocarditisOFFSIDES
66Basal cell carcinomaOFFSIDES
67Benign NeoplasmOFFSIDES
68Bipolar I disorderOFFSIDES
69BlepharospasmOFFSIDES
70Blood albumin abnormalOFFSIDES
71Blood albumin decreasedOFFSIDES
72Blood chloride decreasedOFFSIDES
73Blood cholesterolOFFSIDES
74Blood glucose decreasedOFFSIDES
75Blood potassium decreasedOFFSIDES
76Blood pressure fluctuationOFFSIDES
77Blood sodium increasedOFFSIDES
78Blood sodiumOFFSIDES
79Blood thyroid stimulating hormone increasedOFFSIDES
80Blood urea increasedOFFSIDES
81Blurred visionOFFSIDES
82Bone infarctionOFFSIDES
83Bone lesionOFFSIDES
84Bone painOFFSIDES
85Bone swellingOFFSIDES
86Breast tendernessOFFSIDES
87BruxismOFFSIDES
88Buccal mucosal rougheningOFFSIDES
89BunionOFFSIDES
90BursitisOFFSIDES
91CarcinomaOFFSIDES
92Carotid artery occlusionOFFSIDES
93CataractOFFSIDES
94Catheter site related reactionOFFSIDES
95CausalgiaOFFSIDES
96CellulitisOFFSIDES
97Central nervous system lesionOFFSIDES
98Central venous catheter removalOFFSIDES
99CheilitisOFFSIDES
100Chest PainOFFSIDES
101Choking sensationOFFSIDES
102Chronic Fatigue SyndromeOFFSIDES
103Circumstance or information capable of leading to medication errorOFFSIDES
104CirrhosisOFFSIDES
105Clostridium difficile colitisOFFSIDES
106ColitisOFFSIDES
107ConfabulationOFFSIDES
108Congenital tricuspid valve incompetenceOFFSIDES
109Conjunctival depositOFFSIDES
110CryingOFFSIDES
111CystoceleOFFSIDES
112Deafness NeurosensoryOFFSIDES
113DeafnessOFFSIDES
114DebridementOFFSIDES
115DehydrationOFFSIDES
116Delusional disorder, unspecified typeOFFSIDES
117DemyelinationOFFSIDES
118Dental cariesOFFSIDES
119Dental prosthesis placementOFFSIDES
120DiabetesOFFSIDES
121Diabetic RetinopathyOFFSIDES
122DiarrheaOFFSIDES
123DiplopiaOFFSIDES
124Disease ProgressionOFFSIDES
125Disease recurrenceOFFSIDES
126DiverticulitisOFFSIDES
127DrowsinessOFFSIDES
128Drug ToleranceOFFSIDES
129Drug abuserOFFSIDES
130Drug addictOFFSIDES
131Drug delivery system malfunctionOFFSIDES
132Drug withdrawal headacheOFFSIDES
133DysgeusiaOFFSIDES
134DyspepsiaOFFSIDES
135Dysthymic DisorderOFFSIDES
136DystoniaOFFSIDES
137Ear discomfortOFFSIDES
138Economic problemOFFSIDES
139Electrocardiogram ST-T changeOFFSIDES
140Electrocardiogram poor R-wave progressionOFFSIDES
141Emotional distressOFFSIDES
142EndarterectomyOFFSIDES
143Endodontic procedureOFFSIDES
144Endometrial hypertrophyOFFSIDES
145Essential HypertensionOFFSIDES
146ExcoriationOFFSIDES
147Eye inflammationOFFSIDES
148Eye painOFFSIDES
149Facial NeuralgiaOFFSIDES
150Failure of implantOFFSIDES
151False positive laboratory resultOFFSIDES
152FatigueOFFSIDES
153Fatty LiverOFFSIDES
154FibromyalgiaOFFSIDES
155FlatulenceOFFSIDES
156FormicationOFFSIDES
157Full blood count decreasedOFFSIDES
158GamblingOFFSIDES
159GangreneOFFSIDES
160Gastric BypassOFFSIDES
161Gastric ulcerOFFSIDES
162General physical health deteriorationOFFSIDES
163GlaucomaOFFSIDES
164Graft delaminationOFFSIDES
165Hay feverOFFSIDES
166Hepatitis AOFFSIDES
167Hip surgeryOFFSIDES
168Hypersplenism acquiredOFFSIDES
169HypophagiaOFFSIDES
170HysterectomyOFFSIDES
171IncontinenceOFFSIDES
172Incorrect drug administration rateOFFSIDES
173IndurationOFFSIDES
174Injection site urticariaOFFSIDES
175Intention tremorOFFSIDES
176Intentional drug misuseOFFSIDES
177Intervertebral Disc DegenerationOFFSIDES
178Intervertebral disc disorderOFFSIDES
179Joint Range of Motion DecreasedOFFSIDES
180Joint injuryOFFSIDES
181Joint sprainOFFSIDES
182Kidney FailureOFFSIDES
183Lesion excisionOFFSIDES
184LethargyOFFSIDES
185Life expectancy shortenedOFFSIDES
186Limb injuryOFFSIDES
187Lumbar radiculopathyOFFSIDES
188LymphedemaOFFSIDES
189MarasmusOFFSIDES
190MastectomyOFFSIDES
191Metastatic NeoplasmOFFSIDES
192Micrographic skin surgeryOFFSIDES
193Multiple SclerosisOFFSIDES
194Multiple sclerosis relapseOFFSIDES
195Muscle WeaknessOFFSIDES
196Muscle strainOFFSIDES
197Musculoskeletal stiffnessOFFSIDES
198NasopharyngitisOFFSIDES
199NephrolithiasisOFFSIDES
200Nephrotic SyndromeOFFSIDES
201Nervous tensionOFFSIDES
202NeuralgiaOFFSIDES
203NeurodermatitisOFFSIDES
204NocturiaOFFSIDES
205Ocular vascular disorderOFFSIDES
206Optic AtrophyOFFSIDES
207Optic Disc EdemaOFFSIDES
208Optic NeuropathyOFFSIDES
209Oral infectionOFFSIDES
210Oral mucosal erythemaOFFSIDES
211OsteopeniaOFFSIDES
212OsteosclerosisOFFSIDES
213PCO2 decreasedOFFSIDES
214Pancreatic enlargementOFFSIDES
215ParanoiaOFFSIDES
216Pelvic Floor Muscle WeaknessOFFSIDES
217Pharyngolaryngeal PainOFFSIDES
218PhlebitisOFFSIDES
219PhonophobiaOFFSIDES
220Physical disabilityOFFSIDES
221PleurisyOFFSIDES
222Polysubstance abuseOFFSIDES
223Poor quality drug administeredOFFSIDES
224Portal HypertensionOFFSIDES
225Post procedural complicationOFFSIDES
226Postmenopausal bleedingOFFSIDES
227Primary sequestrumOFFSIDES
228Productive CoughOFFSIDES
229PsoriasisOFFSIDES
230Psychiatric symptomOFFSIDES
231Pulmonary congestionOFFSIDES
232PyelonephritisOFFSIDES
233RegurgitationOFFSIDES
234Renal ColicOFFSIDES
235Renal cystOFFSIDES
236RhinorrheaOFFSIDES
237Risus sardonicusOFFSIDES
238SchizophreniaOFFSIDES
239ScotomaOFFSIDES
240Sinus bradycardiaOFFSIDES
241SinusitisOFFSIDES
242Skin lacerationOFFSIDES
243SnoringOFFSIDES
244Spinal column stenosisOFFSIDES
245SpondylolisthesisOFFSIDES
246Sudden deathOFFSIDES
247TendinitisOFFSIDES
248Tension HeadacheOFFSIDES
249Therapeutic response unexpected with drug substitutionOFFSIDES
250TinnitusOFFSIDES
251Tooth ExtractionOFFSIDES
252Tooth LossOFFSIDES
253Transmission of drug via semenOFFSIDES
254Trisomy 21OFFSIDES
255UlcerOFFSIDES
256Uterine PolypOFFSIDES
257VasospasmOFFSIDES
258Venous InsufficiencyOFFSIDES
259Venous angioma of brainOFFSIDES
260Ventricular FibrillationOFFSIDES
261Ventricular hypokinesiaOFFSIDES
262Vulvovaginal mycotic infectionOFFSIDES
263Walking aid userOFFSIDES
264Weight GainOFFSIDES
265Wound infection staphylococcalOFFSIDES
266effusionOFFSIDES
267prostatitisOFFSIDES
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