Cloxacillin
(LQOLIRLGBULYKD-JKIFEVAISA-N)
Structure
- SMILES
- OC(=O)[C@@H]1N2C(=O)[C@H]([C@H]2SC1(C)C)NC(=O)c1c(C)onc1c1ccccc1Cl
- Type(s)
- Approved; Investigational; Vet_approved
- ATC code(s)
- J01CF02; J01CR50
- Molecular Formula:
- C19H18ClN3O5S
- Molecular Weight:
- 435.881
- Log P:
- 2.8775
- Hydrogen Bond Acceptor:
- 9
- Hydrogen Bond Donor:
- 2
- TPSA:
- 138.04
- CAS Number(s):
- 61-72-3
Synonym(s)
1.
Cloxacillin
2.
Chloroxacillin
3.
Sodium Cloxacillin
4.
Cloxacillin Sodium
5.
Syntarpen
6.
Tegopen
7.
Cloxacillin, Sodium
8.
Sodium, Cloxacillin
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Abdominal Pain | Canada Vigilance: 2 | 11476450 | CTD Canada Vigilance |
| 2 | Abdominal discomfort | Canada Vigilance: 2 | Canada Vigilance | |
| 3 | Acute Coronary Syndrome | OFFSIDES | ||
| 4 | Alanine Aminotransferase Increased | OFFSIDES | ||
| 5 | Amylase increased | Canada Vigilance: 1 | Canada Vigilance | |
| 6 | Anaphylactoid Reaction | Canada Vigilance: 3 | Canada Vigilance | |
| 7 | Anemia, Hemolytic | 4124995 | CTD | |
| 8 | Angioedema | Canada Vigilance: 1 | 16540070 | CTD Canada Vigilance |
| 9 | Anorexia | OFFSIDES | ||
| 10 | Arteritis obliterans | OFFSIDES | ||
| 11 | Arthralgia | 1305739 11476450 | CTD | |
| 12 | Arthritis | Canada Vigilance: 1 | Canada Vigilance | |
| 13 | Arthropathy | OFFSIDES | ||
| 14 | Ascites | 11476450 | CTD | |
| 15 | Asthenia | Canada Vigilance: 4 | Canada Vigilance | |
| 16 | Atrioventricular Block | OFFSIDES | ||
| 17 | Back Pain | 1421648 | CTD | |
| 18 | Biopsy bone marrow abnormal | OFFSIDES | ||
| 19 | Blood creatinine increased | Canada Vigilance: 2 | Canada Vigilance OFFSIDES | |
| 20 | Blood triglycerides increased | OFFSIDES | ||
| 21 | Blood urea increased | Canada Vigilance: 2 | Canada Vigilance | |
| 22 | Bronchial Obstruction | OFFSIDES | ||
| 23 | Bronchopneumonia | OFFSIDES | ||
| 24 | Cellulitis | 16540070 | CTD | |
| 25 | Chemical and Drug Induced Liver Injury | 9538497 11476450 24085192 | CTD | |
| 26 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 27 | Choking sensation | OFFSIDES | ||
| 28 | Cholangiolitis | OFFSIDES | ||
| 29 | Cholestasis | CTD | ||
| 30 | Cholestatic liver injury | OFFSIDES | ||
| 31 | Chromaturia | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 32 | Cirrhosis | OFFSIDES | ||
| 33 | Clostridium difficile infection | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Coagulation factor increased | OFFSIDES | ||
| 35 | Complication associated with device | Canada Vigilance: 1 | Canada Vigilance | |
| 36 | Confusion | 6867701 | CTD | |
| 37 | Cytolytic hepatitis | OFFSIDES | ||
| 38 | Dehydration | Canada Vigilance: 1 | Canada Vigilance | |
| 39 | Dermatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 40 | Device occlusion | Canada Vigilance: 1 | Canada Vigilance | |
| 41 | Diarrhea | 11476450 | CTD | |
| 42 | Dizziness | Canada Vigilance: 3 | Canada Vigilance | |
| 43 | Drug Eruptions | 16540070 | CTD | |
| 44 | Drug ineffective | OFFSIDES | ||
| 45 | Dyspepsia | Canada Vigilance: 3 | Canada Vigilance | |
| 46 | Dyspnea | 11476450 | CTD | |
| 47 | Eczema | Canada Vigilance: 1 | Canada Vigilance | |
| 48 | Edema | 1421648 | CTD | |
| 49 | Ejection fraction abnormal | OFFSIDES | ||
| 50 | Endocarditis | OFFSIDES | ||
| 51 | Eosinophilia | Canada Vigilance: 2 | 7284928 11476450 | CTD Canada Vigilance |
| 52 | Epilepsy | 8487076 | CTD | |
| 53 | Erythema Multiforme | Canada Vigilance: 1 | Canada Vigilance | |
| 54 | Erythema | Canada Vigilance: 9 | Canada Vigilance OFFSIDES | |
| 55 | Exanthema | 11476450 | CTD | |
| 56 | Fatigue | Canada Vigilance: 1 | Canada Vigilance | |
| 57 | Fever | 11476450 | CTD | |
| 58 | Flushing | Canada Vigilance: 3 | Canada Vigilance | |
| 59 | Gastritis | Canada Vigilance: 2 | Canada Vigilance | |
| 60 | Gastroenteritis | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 61 | Gastrointestinal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 62 | Gastrointestinal infection | Canada Vigilance: 1 | Canada Vigilance | |
| 63 | Globulinuria | OFFSIDES | ||
| 64 | Headache | Canada Vigilance: 2 | Canada Vigilance | |
| 65 | Hematuria | 7284928 | CTD | |
| 66 | Hepatic necrosis | OFFSIDES | ||
| 67 | Hepatomegaly | 11476450 | CTD | |
| 68 | Hypercreatininaemia | OFFSIDES | ||
| 69 | Hyperpigmentation | OFFSIDES | ||
| 70 | Hypersensitivity | Canada Vigilance: 3 | Canada Vigilance | |
| 71 | Hypokalemia | 9547205 | CTD | |
| 72 | Hypokinesia | OFFSIDES | ||
| 73 | Infection | OFFSIDES | ||
| 74 | Jaundice, Obstructive | 3776959 7417768 7893901 | CTD | |
| 75 | Leukocytosis | 11476450 | CTD | |
| 76 | Leukopenia | Canada Vigilance: 1 | 7284928 | CTD Canada Vigilance |
| 77 | Lip swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 78 | Lipase increased | Canada Vigilance: 1 | Canada Vigilance | |
| 79 | Loss of personal independence in daily activities | Canada Vigilance: 1 | Canada Vigilance | |
| 80 | Malaise | Canada Vigilance: 1 | Canada Vigilance | |
| 81 | Mastication disorder | OFFSIDES | ||
| 82 | Medication Error | Canada Vigilance: 1 | Canada Vigilance | |
| 83 | Mucocutaneous candidiasis | OFFSIDES | ||
| 84 | Muscle necrosis | OFFSIDES | ||
| 85 | Mydriasis | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Nausea | Canada Vigilance: 13 | 1305739 | CTD Canada Vigilance |
| 87 | Nephritis, Interstitial | CTD | ||
| 88 | Nervousness | Canada Vigilance: 1 | Canada Vigilance | |
| 89 | Neutropenia | Canada Vigilance: 4 | 7284928 | CTD Canada Vigilance |
| 90 | Nipple pain | Canada Vigilance: 1 | Canada Vigilance | |
| 91 | Pallor | Canada Vigilance: 1 | Canada Vigilance | |
| 92 | Pancreatitis | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 93 | Petechiae | Canada Vigilance: 1 | Canada Vigilance | |
| 94 | Pharyngeal swelling | Canada Vigilance: 2 | Canada Vigilance | |
| 95 | Phlebitis | Canada Vigilance: 1 | 7447412 12953952 | CTD Canada Vigilance |
| 96 | Popliteal pulse decreased | OFFSIDES | ||
| 97 | Portal Hypertension | OFFSIDES | ||
| 98 | Post procedural complication | OFFSIDES | ||
| 99 | Product deposit | Canada Vigilance: 2 | Canada Vigilance | |
| 100 | Pruritus | Canada Vigilance: 9 | 7893901 | CTD Canada Vigilance |
| 101 | Psoriasis | OFFSIDES | ||
| 102 | Pulmonary Hypertension | OFFSIDES | ||
| 103 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 104 | Pyogenic granuloma | OFFSIDES | ||
| 105 | Pyuria | 1421648 | CTD | |
| 106 | Rash erythematous | Canada Vigilance: 7 | Canada Vigilance | |
| 107 | Renal Insufficiency | 1421648 | CTD | |
| 108 | Retching | Canada Vigilance: 1 | Canada Vigilance | |
| 109 | Shoulder Pain | OFFSIDES | ||
| 110 | Skin lesion | OFFSIDES | ||
| 111 | Staphylococcal Infections | CTD | ||
| 112 | Stevens-Johnson Syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 113 | Stomatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 114 | Stridor | OFFSIDES | ||
| 115 | Sudden death | OFFSIDES | ||
| 116 | Suppressed lactation | Canada Vigilance: 1 | Canada Vigilance | |
| 117 | Tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 118 | Therapeutic product ineffective | OFFSIDES | ||
| 119 | Urethral Stenosis | OFFSIDES | ||
| 120 | Urticaria | Canada Vigilance: 14 | Canada Vigilance | |
| 121 | Varicose Ulcer | 7249889 | CTD | |
| 122 | Vasculitis | Canada Vigilance: 1 | Canada Vigilance | |
| 123 | Visual Impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 124 | Vitamin K Deficiency | OFFSIDES | ||
| 125 | Vomiting | Canada Vigilance: 10 | 1305739 | CTD Canada Vigilance |
| 126 | Weight decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 127 | jaundice | Canada Vigilance: 2 | 11476450 | CTD Canada Vigilance |
| 128 | pseudomembranous colitis | Canada Vigilance: 1 | Canada Vigilance |
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