MetaADEDB 2.0 @ LMMD
Hydrocortisone sodium succinate
(HHZQLQREDATOBM-CODXZCKSSA-M)
Structure
SMILES
[O-]C(=O)CCC(=O)OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C.[Na+]
Molecular Formula:
C25H33NaO8
Molecular Weight:
484.514
Log P:
0.8626
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
2
TPSA:
141.03
CAS Number(s):
125-04-2
Synonym(s)
1.
Hydrocortisone sodium succinate
External Link(s)
PubChem Compound23694214
ChEBI5782
CHEMBLCHEMBL1200495
KEGGcpd:C08178
dr:D00978
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1BronchospasmFAERS: 7US FAERS
2AsthmaFAERS: 6OFFSIDES
US FAERS
3Drug level above therapeuticFAERS: 6US FAERS
4UrticariaFAERS: 6US FAERS
5PneumoniaFAERS: 4US FAERS
6AgitationFAERS: 3US FAERS
7Anaphylactic shockFAERS: 3US FAERS
8ShockFAERS: 3US FAERS
9AnxietyFAERS: 2US FAERS
10Diabetes InsipidusFAERS: 2US FAERS
11DizzinessFAERS: 2US FAERS
12Intestinal PerforationFAERS: 2US FAERS
13Joint swellingFAERS: 2US FAERS
14PeritonitisFAERS: 2US FAERS
15Respiratory FailureFAERS: 2OFFSIDES
US FAERS
16RestlessnessFAERS: 2US FAERS
17StridorFAERS: 2US FAERS
18Adverse eventFAERS: 1US FAERS
19Altered state of consciousnessFAERS: 1OFFSIDES
US FAERS
20AmnesiaFAERS: 1US FAERS
21Anaphylactoid ReactionFAERS: 1US FAERS
22ArthralgiaFAERS: 1US FAERS
23Benign Prostatic HyperplasiaFAERS: 1US FAERS
24BradycardiaFAERS: 1OFFSIDES
US FAERS
25Cardiac HypertrophyFAERS: 1US FAERS
26Chest discomfortFAERS: 1US FAERS
27Disease recurrenceFAERS: 1OFFSIDES
US FAERS
28EczemaFAERS: 1US FAERS
29ErythemaFAERS: 1US FAERS
30Eye painFAERS: 1US FAERS
31FatigueFAERS: 1US FAERS
32FlushingFAERS: 1US FAERS
33FrustrationFAERS: 1US FAERS
34HeadacheFAERS: 1US FAERS
35Hepatitis BFAERS: 1OFFSIDES
US FAERS
36LethargyFAERS: 1US FAERS
37Mental impairmentFAERS: 1US FAERS
38MydriasisFAERS: 1US FAERS
39PainFAERS: 1US FAERS
40ParaplegiaFAERS: 1US FAERS
41Post procedural complicationFAERS: 1US FAERS
42Psychotic disorder due to a general medical conditionFAERS: 1US FAERS
43Urinary tract infectionFAERS: 1US FAERS
44VomitingFAERS: 1US FAERS
45Abdominal PainOFFSIDES
46AcidosisOFFSIDES
47ActinomycosisOFFSIDES
48Acute myocardial infarctionOFFSIDES
49Acute respiratory failureOFFSIDES
50Adams-Stokes SyndromeOFFSIDES
51Adrenal cortex necrosisOFFSIDES
52Alanine Aminotransferase IncreasedOFFSIDES
53AlveolitisOFFSIDES
54AnorexiaOFFSIDES
55ApathyOFFSIDES
56Aphthous StomatitisOFFSIDES
57AspergillosisOFFSIDES
58Aspiration PneumoniaOFFSIDES
59AtherosclerosisOFFSIDES
60AthetosisOFFSIDES
61Bacterial EndocarditisOFFSIDES
62Bacterial test positiveOFFSIDES
63Blood GlucoseOFFSIDES
64Blood albumin decreasedOFFSIDES
65Blood amylase increasedOFFSIDES
66Blood bilirubin unconjugated increasedOFFSIDES
67Blood chloride decreasedOFFSIDES
68Blood creatinine increasedOFFSIDES
69Blood fibrinogenOFFSIDES
70Blood iron increasedOFFSIDES
71Blood lactate dehydrogenase increasedOFFSIDES
72Blood pH decreasedOFFSIDES
73Blood pressure fluctuationOFFSIDES
74Blood sodium increasedOFFSIDES
75Blood sodiumOFFSIDES
76Blood urea increasedOFFSIDES
77Blood uric acidOFFSIDES
78Body TemperatureOFFSIDES
79Bone marrow depressionOFFSIDES
80BronchitisOFFSIDES
81Bronchoalveolar LavageOFFSIDES
82Burning sensationOFFSIDES
83Cancer PainOFFSIDES
84Central Nervous System InfectionOFFSIDES
85Choking sensationOFFSIDES
86ChokingOFFSIDES
87CirrhosisOFFSIDES
88Clostridium difficile sepsisOFFSIDES
89ClubbingOFFSIDES
90Cold sweatOFFSIDES
91Cytomegalovirus enterocolitisOFFSIDES
92Dental abscessOFFSIDES
93Depressed Level of ConsciousnessOFFSIDES
94Device related infectionOFFSIDES
95DiabetesOFFSIDES
96DiarrheaOFFSIDES
97Diffuse alveolar damageOFFSIDES
98Disease ProgressionOFFSIDES
99Disseminated Intravascular CoagulationOFFSIDES
100Drug ineffectiveCanada Vigilance: 3Canada Vigilance
101Drug withdrawal headacheOFFSIDES
102DysphoniaOFFSIDES
103DysuriaOFFSIDES
104Engraftment syndromeOFFSIDES
105Enterobacter pneumoniaOFFSIDES
106Enterococcal infectionOFFSIDES
107Epstein-Barr virus associated lymphoproliferative disorderOFFSIDES
108Erosive gastritisOFFSIDES
109Escherichia urinary tract infectionOFFSIDES
110ExcoriationOFFSIDES
111Febrile NeutropeniaOFFSIDES
112FibromyalgiaOFFSIDES
113GangreneOFFSIDES
114Gastric ulcerOFFSIDES
115GastroenteritisOFFSIDES
116General nutrition disorderOFFSIDES
117General physical health deteriorationOFFSIDES
118GlossectomyOFFSIDES
119Granulocyte count decreasedOFFSIDES
120Head titubationOFFSIDES
121Heparin-induced thrombocytopeniaOFFSIDES
122Hepatitis B surface antigen negativeOFFSIDES
123Hepatitis C antibody positiveOFFSIDES
124HepatosplenomegalyOFFSIDES
125Histiocytosis haematophagicOFFSIDES
126HydropneumothoraxOFFSIDES
127Hyperosmolar stateOFFSIDES
128HypophagiaOFFSIDES
129HypoxiaOFFSIDES
130Impaired work abilityOFFSIDES
131InfectionOFFSIDES
132Intention tremorOFFSIDES
133Joint sprainOFFSIDES
134Kidney FailureOFFSIDES
135LeukoencephalopathyOFFSIDES
136Leukopenia neonatalOFFSIDES
137Lung consolidationOFFSIDES
138Lymphangiosis carcinomatosaOFFSIDES
139Lymphocyte count decreasedOFFSIDES
140Mechanical ventilationOFFSIDES
141MediastinitisOFFSIDES
142Metabolic acidosisOFFSIDES
143MetatarsalgiaOFFSIDES
144Musculoskeletal chest painOFFSIDES
145NauseaCanada Vigilance: 1Canada Vigilance
OFFSIDES
146Neutrophil count decreasedOFFSIDES
147Ocular icterusOFFSIDES
148Oropharyngeal painOFFSIDES
149PCO2 increasedOFFSIDES
150PallorOFFSIDES
151PancreatitisOFFSIDES
152Peripheral embolismOFFSIDES
153Pharyngolaryngeal PainOFFSIDES
154PneumothoraxOFFSIDES
155Portal HypertensionOFFSIDES
156Portal hypertensive gastropathyOFFSIDES
157Protein total decreasedOFFSIDES
158Protein-losing gastroenteropathyOFFSIDES
159Psychiatric symptomOFFSIDES
160Pulmonary arterial pressure increasedOFFSIDES
161Purulent dischargeOFFSIDES
162Renal tubular necrosisOFFSIDES
163Retinal VasculitisOFFSIDES
164RhabdomyolysisOFFSIDES
165Septic ShockOFFSIDES
166Sjogren's SyndromeOFFSIDES
167Spinal claudicationOFFSIDES
168Sputum culture positiveOFFSIDES
169Sputum retentionOFFSIDES
170Stem cell transplantOFFSIDES
171Steroid withdrawal syndromeOFFSIDES
172Stress ulcerOFFSIDES
173Subcutaneous AbscessOFFSIDES
174SyncopeCanada Vigilance: 1Canada Vigilance
175TenosynovitisOFFSIDES
176Therapeutic product effect incompleteCanada Vigilance: 2Canada Vigilance
177TineaOFFSIDES
178Tooth InfectionOFFSIDES
179Upper airway obstructionOFFSIDES
180Upper respiratory tract inflammationOFFSIDES
181Urinary tract infection enterococcalOFFSIDES
182Urine ketone body presentOFFSIDES
183Vascular insufficiencyOFFSIDES
184White blood cell count abnormalOFFSIDES
185effusionOFFSIDES
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