MetaADEDB 2.0 @ LMMD
Vitamin K 1
(MBWXNTAXLNYFJB-NKFFZRIASA-N)
Structure
SMILES
C[C@H](CCC[C@@H](CCCC(C)C)C)CCC/C(=C/CC1=C(C)C(=O)c2c(C1=O)cccc2)/C
Type(s)
Approved; Investigational
ATC code(s)
B02BA01
Molecular Formula:
C31H46O2
Molecular Weight:
450.696
Log P:
9.1576
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
34.14
CAS Number(s):
84-80-0; 11104-38-4; 79083-00-4
Synonym(s)
1.
Vitamin K 1
2.
Phylloquinone
3.
Phytomenadione
4.
Phytonadione
5.
Aquamephyton
6.
Konakion
7.
Phyllohydroquinone
8.
Vitamin K1
External Link(s)
MeSHD010837
PubChem Compound5284607
BindingDB24782
ChEBI18067
CHEMBLCHEMBL1550
DrugBankDB01022
DrugCentral2843
KEGGcpd:C02059
dr:D00148
ZINC3831332
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Injury associated with deviceFAERS: 42US FAERS
2Needle issueFAERS: 7US FAERS
3HypotensionFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
4Medication ErrorFAERS: 6US FAERS
5Accidental needle stickFAERS: 5OFFSIDES
US FAERS
6Device malfunctionFAERS: 5OFFSIDES
US FAERS
7DizzinessFAERS: 5US FAERS
8Respiratory FailureFAERS: 5
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
9Unresponsive to stimuliFAERS: 5OFFSIDES
US FAERS
10ChillsFAERS: 4US FAERS
11FlushingFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
12HypoxiaFAERS: 4OFFSIDES
US FAERS
13TremorFAERS: 4US FAERS
14Back PainFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
15Chest PainFAERS: 3OFFSIDES
US FAERS
16CyanosisFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
17ErythemaFAERS: 3US FAERS
18TachycardiaFAERS: 3US FAERS
19Anaphylactic shockFAERS: 2US FAERS
20AstheniaFAERS: 2OFFSIDES
US FAERS
21Chest discomfortFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
22Circumstance or information capable of leading to medication errorFAERS: 2OFFSIDES
US FAERS
23Device breakageFAERS: 2OFFSIDES
US FAERS
24Drug dispensing errorFAERS: 2US FAERS
25EmbolismFAERS: 2US FAERS
26Exposure via contaminated deviceFAERS: 2US FAERS
27Medical device complicationFAERS: 2US FAERS
28NauseaFAERS: 2OFFSIDES
US FAERS
29PainFAERS: 2OFFSIDES
US FAERS
30Pharmaceutical product complaintFAERS: 2US FAERS
31Product packaging issueFAERS: 2US FAERS
32Product quality issueFAERS: 2US FAERS
33Pulmonary EmbolismFAERS: 2US FAERS
34VomitingFAERS: 2US FAERS
35jaundiceFAERS: 2US FAERS
36Abdominal AbscessFAERS: 1US FAERS
37Abdominal PainFAERS: 1OFFSIDES
US FAERS
38Abdominal wound dehiscenceFAERS: 1US FAERS
39Accidental exposure to productFAERS: 1US FAERS
40Acute myocardial infarctionFAERS: 1US FAERS
41AgitationFAERS: 1US FAERS
42Atrial FibrillationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
43BradycardiaFAERS: 1OFFSIDES
US FAERS
44Cerebrovascular accidentFAERS: 1US FAERS
45CryingFAERS: 1US FAERS
46Deep Vein ThrombosisFAERS: 1US FAERS
47Depressed Level of ConsciousnessFAERS: 1US FAERS
48Device use errorFAERS: 1US FAERS
49DiverticulumFAERS: 1OFFSIDES
US FAERS
50Drug administration errorFAERS: 1US FAERS
51Drug ineffectiveFAERS: 1US FAERS
52Electromechanical dissociationFAERS: 1OFFSIDES
US FAERS
53Feeling ColdFAERS: 1OFFSIDES
US FAERS
54Feeling abnormalFAERS: 1US FAERS
55Foreign body traumaFAERS: 1US FAERS
56General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
57Iatrogenic injuryFAERS: 1US FAERS
58Incorrect dose administeredFAERS: 1US FAERS
59Incorrect drug administration rateFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
60Incorrect route of product administrationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
61Injection Site ReactionFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
62Intercepted medication errorFAERS: 1US FAERS
63LacerationFAERS: 1OFFSIDES
US FAERS
64Limb injuryFAERS: 1OFFSIDES
US FAERS
65Lip swellingFAERS: 1US FAERS
66Mental status changesFAERS: 1OFFSIDES
US FAERS
67Neck PainFAERS: 1US FAERS
68No adverse eventFAERS: 1US FAERS
69Occult blood positiveFAERS: 1US FAERS
70Occupational exposure to productFAERS: 1US FAERS
71Product container seal issueFAERS: 1US FAERS
72Product label confusionFAERS: 1US FAERS
73Product label issueFAERS: 1US FAERS
74Product packaging confusionFAERS: 1US FAERS
75Product substitution issueFAERS: 1US FAERS
76PruritusFAERS: 1US FAERS
77Rash erythematousFAERS: 1US FAERS
78Reaction to drug excipientsFAERS: 1US FAERS
79Respiratory arrestFAERS: 1US FAERS
80Secretion dischargeFAERS: 1US FAERS
81SepsisFAERS: 1US FAERS
82Skin lacerationFAERS: 1US FAERS
83Syringe issueFAERS: 1US FAERS
84Tongue bitingFAERS: 1US FAERS
85Tooth ExtractionFAERS: 1OFFSIDES
US FAERS
86Unevaluable eventFAERS: 1US FAERS
87Vascular stent thrombosisFAERS: 1US FAERS
88Ventricular FibrillationFAERS: 1OFFSIDES
US FAERS
89Wrong patient received medicationFAERS: 1US FAERS
90Wrong technique in drug usage processFAERS: 1US FAERS
91Abdominal discomfortOFFSIDES
92Abnormal visionOFFSIDES
93AbscessOFFSIDES
94AcidosisOFFSIDES
95Acute Coronary SyndromeOFFSIDES
96Acute left ventricular failureOFFSIDES
97Acute otitis mediaOFFSIDES
98Acute respiratory failureOFFSIDES
99AdenomaOFFSIDES
100Alanine Aminotransferase IncreasedOFFSIDES
101AlkalosisOFFSIDES
102AlveolitisOFFSIDES
103Ammonia increasedOFFSIDES
104AnorexiaOFFSIDES
105Antibiotic level above therapeuticOFFSIDES
106Antithrombin III decreasedOFFSIDES
107AnuriaOFFSIDES
108AnxietyOFFSIDES
109AphakiaOFFSIDES
110Aphthous StomatitisOFFSIDES
111Apolipoprotein increasedOFFSIDES
112Application site rashOFFSIDES
113Application site vesiclesOFFSIDES
114ArteriosclerosisOFFSIDES
115AscitesOFFSIDES
116AsphyxiaOFFSIDES
117AsterixisOFFSIDES
118AtelectasisOFFSIDES
119Atrial FlutterOFFSIDES
120Atrial tachycardiaOFFSIDES
121Autoimmune hepatitisOFFSIDES
122Autologous bone marrow transplantation therapyOFFSIDES
123AutomatismOFFSIDES
124Basal ganglion degenerationOFFSIDES
125Biopsy liver abnormalOFFSIDES
126Blood GlucoseOFFSIDES
127Blood albumin decreasedOFFSIDES
128Blood alkaline phosphatase increasedOFFSIDES
129Blood amylase increasedOFFSIDES
130Blood cholinesterase decreasedOFFSIDES
131Blood creatine phosphokinase increasedOFFSIDES
132Blood creatinine decreasedOFFSIDES
133Blood creatinine increasedOFFSIDES
134Blood fibrinogen increasedOFFSIDES
135Blood gases abnormalOFFSIDES
136Blood magnesium decreasedOFFSIDES
137Blood potassium increasedOFFSIDES
138Blood product transfusion dependentOFFSIDES
139Blood sodium increasedOFFSIDES
140Blood sodiumOFFSIDES
141Blood urea increasedOFFSIDES
142Body TemperatureOFFSIDES
143Bone lesionOFFSIDES
144Bone painOFFSIDES
145Brain natriuretic peptide increasedOFFSIDES
146Bronchoalveolar LavageOFFSIDES
147BronchopneumoniaOFFSIDES
148Calcinosis21193197CTD
149Candidiasis of vaginaOFFSIDES
150CandiduriaOFFSIDES
151Cardiac ArrestCanada Vigilance: 1Canada Vigilance
152Cardiac enzymes increasedOFFSIDES
153Cardioactive drug level increasedOFFSIDES
154Cataract operationOFFSIDES
155Catheter related infectionOFFSIDES
156Catheter sepsisOFFSIDES
157Catheter site erythemaOFFSIDES
158Catheter site painOFFSIDES
159CellulitisOFFSIDES
160Central Nervous System InfectionOFFSIDES
161Cerebral Hemorrhage1723166CTD
162Cerebral PalsyOFFSIDES
163Cerebral artery occlusionOFFSIDES
164Cerebral ventricle dilatationOFFSIDES
165Choking sensationOFFSIDES
166CholangiolitisOFFSIDES
167CirrhosisOFFSIDES
168Cleft PalateOFFSIDES
169ClonusOFFSIDES
170ColitisOFFSIDES
171Complications of transplant surgeryOFFSIDES
172ConfabulationOFFSIDES
173Congenital nystagmusOFFSIDES
174Congenital tricuspid valve incompetenceOFFSIDES
175Culture positiveOFFSIDES
176Culture wound positiveOFFSIDES
177CystOFFSIDES
178Cytolytic hepatitisOFFSIDES
179Cytomegalovirus testOFFSIDES
180Delayed sleep phaseOFFSIDES
181Delusional disorder, unspecified typeOFFSIDES
182DemyelinationOFFSIDES
183Depressed moodOFFSIDES
184Device FailureOFFSIDES
185Device related infectionOFFSIDES
186DiarrheaOFFSIDES
187Dilatation intrahepatic duct acquiredOFFSIDES
188Disabled relativeOFFSIDES
189Disease ProgressionOFFSIDES
190Disseminated Intravascular CoagulationOFFSIDES
191Distal intestinal obstruction syndromeOFFSIDES
192DiverticulitisOFFSIDES
193Drug Eruptions8936071CTD
194Drug exposure during pregnancyOFFSIDES
195Drug toxicityOFFSIDES
196Dyspnoea exacerbatedOFFSIDES
197Economic problemOFFSIDES
198Eczema8936071CTD
199Endodontic procedureOFFSIDES
200Enterococcal infectionOFFSIDES
201Enterococcal sepsisOFFSIDES
202EpilepsyOFFSIDES
203EpistaxisOFFSIDES
204Erosive gastritisOFFSIDES
205Escherichia urinary tract infectionOFFSIDES
206Failure to ThriveOFFSIDES
207FatigueOFFSIDES
208Fatty LiverOFFSIDES
209Febrile NeutropeniaOFFSIDES
210Fluid imbalanceOFFSIDES
211Fluid overloadOFFSIDES
212Fracture treatmentOFFSIDES
213Gamma-Glutamyltransferase IncreasedOFFSIDES
214GangreneOFFSIDES
215GastroenteritisOFFSIDES
216General physical conditionOFFSIDES
217GranulocytosisOFFSIDES
218GranulomaOFFSIDES
219Hematoma1723166CTD
220HemiparesisOFFSIDES
221Heparin-induced thrombocytopeniaOFFSIDES
222Hepatic necrosisOFFSIDES
223Hepatitis B positiveOFFSIDES
224HepatitisOFFSIDES
225HepatotoxicityOFFSIDES
226HydrocephalusOFFSIDES
227HypercreatininaemiaOFFSIDES
228Hypertensive cardiomyopathyOFFSIDES
229Hypertensive heart diseaseOFFSIDES
230Hypothalamo-pituitary disorderOFFSIDES
231ImmunosuppressionOFFSIDES
232Impaired gastric emptyingOFFSIDES
233Implant site infectionOFFSIDES
234Infantile apnoeic attackOFFSIDES
235Injection site painCanada Vigilance: 1Canada Vigilance
236Inspiratory capacity decreasedOFFSIDES
237Intermittent ClaudicationOFFSIDES
238Intervertebral Disc DegenerationOFFSIDES
239Intestinal PerforationOFFSIDES
240IridoceleOFFSIDES
241Jugular vein distensionOFFSIDES
242Kidney FailureOFFSIDES
243LethargyOFFSIDES
244Leukopenia neonatalOFFSIDES
245LipaseOFFSIDES
246Lower respiratory tract infection fungalOFFSIDES
247Lower respiratory tract infection viralOFFSIDES
248Lung consolidationOFFSIDES
249Lung infection pseudomonalOFFSIDES
250MalabsorptionOFFSIDES
251Mental RetardationOFFSIDES
252Metabolic acidosisOFFSIDES
253Metastases to abdominal cavityOFFSIDES
254Metastatic Renal Cell CarcinomaOFFSIDES
255Metastatic painOFFSIDES
256MicrolithiasisOFFSIDES
257Musculoskeletal discomfortOFFSIDES
258Myoglobin blood increasedOFFSIDES
259Myoglobin urine presentOFFSIDES
260Neonatal hypotensionOFFSIDES
261NeuromaOFFSIDES
262Ocular icterusOFFSIDES
263OliguriaOFFSIDES
264OrthopneaOFFSIDES
265OsteomyelitisOFFSIDES
266PCO2 decreasedOFFSIDES
267Pain of skinOFFSIDES
268PallorOFFSIDES
269PancreatitisOFFSIDES
270Pericardial effusionOFFSIDES
271Pilonidal cyst congenitalOFFSIDES
272PneumopericardiumOFFSIDES
273PneumothoraxOFFSIDES
274Portal HypertensionOFFSIDES
275Portal hypertensive gastropathyOFFSIDES
276Post procedural complicationOFFSIDES
277Post procedural painOFFSIDES
278Procedural complicationOFFSIDES
279Productive CoughOFFSIDES
280Protein total decreasedOFFSIDES
281Protein total increasedOFFSIDES
282Pseudobulbar PalsyOFFSIDES
283Pulmonary EosinophiliaOFFSIDES
284Pulmonary HypertensionOFFSIDES
285Pulmonary congestionOFFSIDES
286Pulmonary function test decreasedOFFSIDES
287Pulmonary thrombosisOFFSIDES
288Red blood cell schistocytes presentOFFSIDES
289Refusal of treatment by relativeOFFSIDES
290Renal tubular acidosisOFFSIDES
291Renal tubular necrosisOFFSIDES
292RhabdomyolysisOFFSIDES
293ScotomaOFFSIDES
294Septic ShockOFFSIDES
295Serratia sepsisOFFSIDES
296Shoulder PainOFFSIDES
297Sick Sinus SyndromeOFFSIDES
298Skin lesionOFFSIDES
299Skin necrosisOFFSIDES
300Skin toxicityOFFSIDES
301Spinal column stenosisOFFSIDES
302Splenic InfarctionOFFSIDES
303SpondylolisthesisOFFSIDES
304Sputum culture positiveOFFSIDES
305Stem cell transplantOFFSIDES
306Stevens-Johnson SyndromeOFFSIDES
307StridorOFFSIDES
308Synovial CystOFFSIDES
309TendinitisOFFSIDES
310Thalamic infarctionOFFSIDES
311ThrombectomyOFFSIDES
312ToxoplasmosisOFFSIDES
313TracheobronchitisOFFSIDES
314Troponin I increasedOFFSIDES
315Troponin increasedOFFSIDES
316Unequal Limb LengthOFFSIDES
317Urinary tract infection enterococcalOFFSIDES
318Vanishing bile duct syndromeOFFSIDES
319Vascular calcification23990204
27412937		CTD
320Venoocclusive diseaseOFFSIDES
321Ventricular hypokinesiaOFFSIDES
322Vitamin K DeficiencyOFFSIDES
323White blood cell count abnormalOFFSIDES
324Wound infection fungalOFFSIDES
325jejunitisOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120235

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.