MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Gastrointestinal Diseases

(UMLS:C0017178)

Definition:: Diseases in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
UMLS ID:: C0017178
MeSH ID:: D005767

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405

Synonym(s)

Gastrointestinal Diseases

Digestive Disease

Digestive System Disease

Digestive System Disorder

Disease;digestive

Disorder of Digestive System

Disorder of gastrointestinal tract

Disorder of gastrointestinal tract, NOS

GASTRO-INTESTINAL DISORDER NOS

10.

GASTROINTESTINAL DISEASE

11.

GASTROINTESTINAL DISORDER

12.

GI disorders

13.

GIT diseases

14.

Gastroenteropathy

15.

Gastrointestinal Disorder

16.

Gastrointestinal Disorders

17.

Gastrointestinal System Disease

Associated Drug(s)

	Name	Reference(s)	Data Source
1	5-FU-CDDP protocol	17084549	CTD
2	AZD3514	26876616	CTD
3	Acetylcysteine	5305168 15496615	CTD
4	Alcohols	7481522 17709257	CTD
5	Allopurinol	1285366	CTD
6	Alprostadil	1613947	CTD
7	Altretamine	219695	CTD
8	Amantadine	7347558	CTD
9	Amifostine	11161394	CTD
10	Aminophylline	3898925	CTD
11	Amiodarone	View details 3158188 3271193 6685151 16858166	CTD
12	Amoxicillin-Potassium Clavulanate Combination	8354296	CTD
13	Amoxicillin	9636854	CTD
14	Amsacrine	3463435	CTD
15	Arsenicals	18308700	CTD
16	Aspirin	View details 3055941 4853118 7889238 8144103 9781830 12848632 17339622 18604318 18984426 19297216	CTD
17	Atovaquone	11130385	CTD
18	Atropine	18467537	CTD
19	Auranofin	3932651	CTD
20	Azathioprine	View details 1818543 4733959 15792824 22535280	CTD
21	Azauridine	4552812	CTD
22	Azithromycin	9142801 19336954	CTD
23	Benzbromarone	680625	CTD
24	Bortezomib	View details 15738379 19274460 20150504 24673398	CTD
25	Bromocriptine	15050800	CTD
26	Budesonide	20223723 21885873	CTD
27	Busulfan	10955873	CTD
28	CEF regimen	17430667	CTD
29	Caffeine	16184581	CTD
30	Carbon Monoxide	20049132	CTD
31	Carboplatin	11161394	CTD
32	Carmustine	7960606	CTD
33	Cefotiam	6317911	CTD
34	Celecoxib	16187199 17084549 18604318	CTD
35	Chloroquine	11130385 12170684	CTD
36	Chlorzoxazone	7299979	CTD
37	Cinacalcet	19715927	CTD
38	Cinoxacin	6362163	CTD
39	Clioquinol	4101631	CTD
40	Cocaine	17044582	CTD
41	Codeine	6526987	CTD
42	Colchicine	10455999 17505274	CTD
43	Copper Sulfate	29705531	CTD
44	Copper	20035423	CTD
45	Crizotinib	20979469 23020724	CTD
46	Cyclophosphamide	19274460 24673398	CTD
47	Cyclosporine	1818543 10455999	CTD
48	Cytarabine	2411382 3463435	CTD
49	Dacarbazine	7960606	CTD
50	Dexamethasone	View details 1619017 11150359 19274460 24673398	CTD
51	Diane	10857213	CTD
52	Dichlorvos	24430101	CTD
53	Diclofenac	View details 15234645 15834531 17304660 17965424 19223284 21295044 24185126 25014874	CTD
54	Diethylnitrosamine	8144103	CTD
55	Diflunisal	25014874	CTD
56	Dipyridamole	1395766 18984426	CTD
57	Donepezil	16820527	CTD
58	Doxorubicin	309102	CTD
59	Doxycycline	16291409 17103211 17826578	CTD
60	Ergolines	11487183	CTD
61	Erlotinib Hydrochloride	24768708	CTD
62	Estramustine	866798 3525866	CTD
63	Ethinyl Estradiol-Norgestrel Combination	4272507 12057783	CTD
64	Ethionamide	5978332	CTD
65	Etoposide	11161394	CTD
66	Famotidine	10353594 11998377	CTD
67	Fleroxacin	2511802 9309373	CTD
68	Floxuridine	1825358	CTD
69	Fluorouracil	View details 7040929 7960606 8053919 12364819 17430663	CTD
70	Fluoxetine	10505588	CTD
71	Flurbiprofen	3514310	CTD
72	Fluvoxamine	1600911 8923094	CTD
73	Glutathione	9199886	CTD
74	Hydroxychloroquine	10229401	CTD
75	Hypoxanthine	9199886	CTD
76	Ibuprofen	6993669	CTD
77	Ifosfamide	11161394	CTD
78	Imipramine	3918993	CTD
79	Indinavir	15824372	CTD
80	Indomethacin	View details 333681 3329590 3896659 8222739 8949638 9502396 16187199 19220725 20035423 25014874	CTD
81	Irinotecan	12911669	CTD
82	Isoniazid	785735 6328384 17310776	CTD
83	Ivermectin	20307935 20471177	CTD
84	Ketoconazole	2728148	CTD
85	Ketoprofen	8222739 17485922	CTD
86	Labetalol	2867049	CTD
87	Lamotrigine	10448828	CTD
88	Lansoprazole	10353594 10692753 12729842	CTD
89	Lenalidomide	20052472	CTD
90	Leucovorin	17430663	CTD
91	Levamisole	68226 282447	CTD
92	Levodopa	1549199 4102620	CTD
93	Linezolid	20639754	CTD
94	Lithium Carbonate	4942959	CTD
95	Lithium	12352283	CTD
96	Lomustine	21418164	CTD
97	Lovastatin	8481075	CTD
98	Mechlorethamine	6089632	CTD
99	Medigoxin	1845639	CTD
100	Mefenamic Acid	25372302	CTD
101	Mefloquine	8161647	CTD
102	Melatonin	19220725	CTD
103	Meloxicam	15234645	CTD
104	Melphalan	6403413 10955873	CTD
105	Mercaptopurine	4552812	CTD
106	Methamphetamine	8341891	CTD
107	Methimazole	2523194	CTD
108	Methotrexate	View details 309102 3913775 7040929 7966062 10599370 18381794 19159907 19648163 25124723	CTD
109	Metoclopramide	View details 2595431 2684075 6727060 7059869 8803308	CTD
110	Metronidazole	6336861 14731313	CTD
111	Mexiletine	3318368	CTD
112	Minocycline	16291409	CTD
113	Misoprostol	8098402	CTD
114	Mitotane	1517795	CTD
115	Mometasone Furoate	21885873	CTD
116	Morphine	11180040	CTD
117	Mycophenolic Acid	17318074	CTD
118	Naloxone	6526987 15167188	CTD
119	Naproxen	View details 7670796 12017396 14753029 15093759 15234645 16172183 25014874	CTD
120	Nevirapine	19721097	CTD
121	Niacin	3547004 14614780	CTD
122	Nifedipine	3985522	CTD
123	Nitrofurantoin	6282377 15247700	CTD
124	Nitroglycerin	3985522	CTD
125	Norfloxacin	1621752	CTD
126	Ofloxacin	9309373	CTD
127	Olmesartan Medoxomil	20528002	CTD
128	Omeprazole	19617305	CTD
129	Orlistat	12975638 19588440	CTD
130	Oxygen	29427784	CTD
131	Paclitaxel	8751544 15923795 20052472	CTD
132	Paraquat	26099602 29723724	CTD
133	Penicillamine	691197 2939913 2952797	CTD
134	Pentagastrin	7481522	CTD
135	Pentazocine	1123460	CTD
136	Pergolide	12601100	CTD
137	Phenylbutazone	6869982	CTD
138	Piroxicam	15234645 19534045	CTD
139	Prajmaline	1261401	CTD
140	Prednisolone	17485922 19336998 20083519	CTD
141	Prednisone	5025095 5254045 6089632	CTD
142	Probenecid	5667986	CTD
143	Procarbazine	6089632	CTD
144	Proguanil	11130385 12170684	CTD
145	Propranolol	4151696	CTD
146	Pyrantel Pamoate	20307935 20307936 20471177	CTD
147	Quinidine	3318368	CTD
148	Rabeprazole	12848632	CTD
149	Ranitidine	1285366	CTD
150	Reserpine	937377	CTD
151	Rifampin	20497752	CTD
152	Rimantadine	7347558	CTD
153	Ritonavir	10093594	CTD
154	Rotenone	14766796	CTD
155	Semustine	4809462	CTD
156	Sertraline	2258378 9832348 10596735	CTD
157	Sorafenib	21735354	CTD
158	Spironolactone	4740303	CTD
159	Styrene	12777181	CTD
160	Sulfasalazine	1972633	CTD
161	Sunitinib	22343322	CTD
162	Tacrolimus	9267719 10743694	CTD
163	Tegafur	1268838	CTD
164	Teniposide	4609765	CTD
165	Theophylline	1835291 7826681 9164358	CTD
166	Thiotepa	10955873	CTD
167	Ticlopidine	1923914	CTD
168	Timolol	6125102 7402590	CTD
169	Topotecan	17399850	CTD
170	Trientine	6445305	CTD
171	Trimethoprim, Sulfamethoxazole Drug Combination	7051241	CTD
172	Valproic Acid	View details 3107169 6798491 15767218 18042239	CTD
173	Vincristine	View details 1939879 4294312 5254045 6089632 6150069 7960606	CTD
174	Vindesine	6707719 7038420	CTD
175	Vinorelbine	9256899	CTD
176	Vitamin D	15460982	CTD
177	Vitamin E	9199886 30003487	CTD
178	Vorinostat	19903873	CTD
179	Zonisamide	3924586	CTD
180	alvimopan	11180040	CTD
181	anethole	17709257	CTD
182	benoxaprofen	6993665 6993669	CTD
183	beraprost	8761844 10353594	CTD
184	beta-Cyclodextrins	12017396	CTD
185	carbidopa, levodopa drug combination	847450	CTD
186	chloramphenicol succinate	4825630	CTD
187	chlorozotocin	6239538	CTD
188	cinitapride	1820589	CTD
189	deoxynivalenol	20633634	CTD
190	efavirenz	19721097	CTD
191	eniluracil	8053919	CTD
192	flunisolide	21885873	CTD
193	gemcitabine	17430667	CTD
194	geranylgeranylacetone	16324314	CTD
195	gimeracil	12364819	CTD
196	indobufen	9127122	CTD
197	mefloquine-sulfadoxine-pyrimethamine	2694482	CTD
198	methotrexate polyglutamate	20954192	CTD
199	milbemycin	20471177	CTD
200	nimesulide	12017396 18604318	CTD
201	perhexiline maleate	470697 4601875	CTD
202	phoxim	30003487	CTD
203	potassium oxonate	12364819	CTD
204	rofecoxib	15834531	CTD
205	tenoxicam	1778090	CTD
206	ticarcillin-clavulanic acid	3722045	CTD
207	tizanidine	15834531	CTD
208	xanomeline	21682298	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Biliary Tract Diseases	33.3%
2	Liver diseases	33.3%
3	Pancreatic Diseases	33.3%
4	Biliary cirrhosis	24.7%
5	Cholecystolithiasis	23.8%
6	Bile Duct Diseases	23.1%
7	Cholelithiasis	23.1%
8	Chylous Ascites	23.1%
9	Fatty Liver	23.1%
10	Hepatitis	23.1%
11	Portal Hypertension	23.1%
12	Liver Cirrhosis	23.1%
13	Pancreatic Insufficiency	23.1%
14	Pancreatitis	23.1%
15	Pneumoperitoneum	23.1%
16	Focal Nodular Hyperplasia	23.1%
17	Hepatic Insufficiency	23.1%
18	Steatohepatitis	23.1%
19	Choledocholithiasis	22.4%
20	Liver neoplasms	21.8%
21	Pancreatic Fistula	21.6%
22	Digestive System Neoplasms	21.1%
23	Bile Duct Neoplasms	20.7%
24	gallbladder neoplasm	20.7%
25	Cholangitis	18.5%
26	Cholecystitis	18.5%
27	Cholestasis	18.5%
28	Common Bile Duct Diseases	18.5%
29	Hepatitis, Chronic	18.5%
30	Liver Failure	18.5%
31	Pancreatitis, Chronic	18.5%
32	Non-alcoholic Fatty Liver Disease	18.5%
33	Chronic active hepatitis	18.5%
34	Fatty Liver, Alcoholic	17.3%
35	Hepatitis, Alcoholic	17.3%
36	Liver Cirrhosis, Alcoholic	17.3%
37	Peritoneal Neoplasms	17.1%
38	Cholestasis, Extrahepatic	16.4%
39	Biliary Dyskinesia	16.4%
40	Cholangitis, Sclerosing	16.4%
41	Liver Failure, Acute	16.4%
42	Acalculous Cholecystitis	16.4%
43	End Stage Liver Disease	16.4%
44	Liver Diseases, Parasitic	15.8%
45	Choledochal Cyst	15.7%
46	Massive Hepatic Necrosis	15.3%
47	Emphysematous Cholecystitis	15.3%
48	Sphincter of Oddi Dysfunction	15.3%
49	Hepatic Veno-Occlusive Disease	15%
50	Pancreatic Cyst	15%
51	Peliosis Hepatis	15%
52	Hepatopulmonary Syndrome	15%
53	Anus, Imperforate	14.6%
54	Hemoperitoneum	14.6%
55	Hepatomegaly	14.6%
56	Mesenteric Panniculitis	14.6%
57	Panniculitis, Peritoneal	14.6%
58	Peritonitis	14.6%
59	Peritoneal Fibrosis	14.6%
60	Encapsulating Peritoneal Sclerosis	14.6%
61	Anorectal Malformations	14.6%
62	Biliary Fistula	14.5%
63	Gastric Fistula	14.5%
64	Hepatic Vein Thrombosis	14.4%
65	Liver Abscess	14.4%
66	Budd-Chiari Syndrome	14.4%
67	Pancreatic Neoplasm	14.3%
68	Hepatocellular Adenoma	13.7%
69	Hepatitis, Animal	12.8%
70	Hepatitis, Viral, Human	12.8%
71	Esophageal and Gastric Varices	11.9%
72	Liver Cirrhosis, Experimental	11.9%
73	Pancreatic Pseudocyst	11.9%
74	Hepatitis B, Chronic	11.9%
75	Hepatitis C, Chronic	11.9%
76	Pancreatitis, Alcoholic	11.8%
77	Liver Abscess, Amebic	11.5%
78	Liver Neoplasms, Experimental	11.5%
79	Chemical and Drug Induced Liver Injury	11.1%
80	Gastrointestinal Neoplasms	10.9%
81	Mesenteric vascular insufficiency	10.9%
82	Autoimmune hepatitis	10.8%
83	Esophageal Atresia	10.7%
84	Intestinal Atresia	10.7%
85	Mesenteric Vascular Occlusion	10.7%
86	Hepatorenal Syndrome	10.6%
87	Intestinal Fistula	10.6%
88	Enterocutaneous Fistula	10.6%
89	Fascioliasis	8.9%
90	Echinococcosis, Hepatic	8.8%
91	Cystic Fibrosis	8.8%
92	Chemical and Drug Induced Liver Injury, Chronic	8.8%
93	Reye Syndrome	8.7%
94	Gastrointestinal Stromal Tumors	8.7%
95	insulinoma	8.5%
96	Gastrinoma	8.5%
97	Glucagonoma	8.5%
98	Porphyrias, Hepatic	8.5%
99	Congenital Hyperinsulinism	8.5%
100	Hepatitis, Viral, Animal	8.4%
101	Carcinoma, Pancreatic Ductal	8.4%
102	Hepatitis E	8.1%
103	Hepatitis B	8%
104	Hepatitis C	8%
105	Hepatitis A	7.9%
106	Hepatic Encephalopathy	7.8%
107	Vipoma	7.4%
108	Intestinal Neoplasms	6.9%
109	Stomach Neoplasms	6.9%
110	Nesidioblastosis	6.8%
111	Variegate Porphyria	6.8%
112	Acute intermittent porphyria	6.8%
113	Porphyria Cutanea Tarda	6.8%
114	Rectal Fistula	6.8%
115	Anal Fistula	6.8%
116	Esophageal Neoplasms	5.7%
117	Cecal Neoplasms	5%
118	Duodenal Neoplasms	5%
119	Appendiceal Neoplasms	4.7%
120	Colonic Neoplasms	4.7%
121	Rectal Neoplasms	4.7%
122	Colorectal Neoplasms	4.3%
123	Zollinger-Ellison syndrome	4.2%
124	Rift Valley Fever	4.2%
125	Anus Neoplasms	3.8%
126	Sigmoid Neoplasms	3.8%
127	Zellweger Syndrome	3.6%
128	Hepatolenticular Degeneration	3.3%
129	Adenomatous Polyposis Coli	2.8%

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