MetaADEDB 2.0 @ LMMD
Pimozide
(YVUQSNJEYSNKRX-UHFFFAOYSA-N)
Structure
SMILES
Fc1ccc(cc1)C(c1ccc(cc1)F)CCCN1CCC(CC1)n1c(=O)[nH]c2c1cccc2
Type(s)
Approved
ATC code(s)
N05AG02
Molecular Formula:
C28H29F2N3O
Molecular Weight:
461.546
Log P:
5.7949
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
41.03
CAS Number(s):
2062-78-4
Synonym(s)
1.
Pimozide
2.
Antalon
3.
Orap
4.
Orap forte
5.
R-6238
6.
R6238
External Link(s)
MeSHD010868
PubChem Compound16362
BindingDB50334150
ChEBI8212
CHEMBLCHEMBL1423
DrugBankDB01100
DrugCentral2172
IUPHAR/BPS Guide to PHARMACOLOGY90
KEGGcpd:C07566
dr:D00560
Therapeutic Target DatabaseD00KHM
ZINC4175630
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1TremorFAERS: 10
Canada Vigilance: 1

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6621715
15680188
17594079
18508458
19467297
19958787
 		CTD
SIDER
Canada Vigilance
US FAERS
2SomnolenceFAERS: 8SIDER
US FAERS
3Drug exposure during pregnancyFAERS: 6US FAERS
4DysuriaFAERS: 5US FAERS
5Accidental overdoseFAERS: 4US FAERS
6Activities of daily living impairedFAERS: 4US FAERS
7OverdoseFAERS: 4OFFSIDES
US FAERS
8Weight decreasedFAERS: 4
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
9Accidental exposureFAERS: 3OFFSIDES
US FAERS
10AstheniaFAERS: 3SIDER
US FAERS
11Complications of maternal exposure to therapeutic drugsFAERS: 3OFFSIDES
US FAERS
12DementiaFAERS: 3US FAERS
13Diabetes MellitusFAERS: 3US FAERS
14DizzinessFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
15Drug dispensing errorFAERS: 3US FAERS
16Drug ineffectiveFAERS: 3US FAERS
17Drug prescribing errorFAERS: 3US FAERS
18DystoniaFAERS: 31322069
7093626
8496127		CTD
OFFSIDES
US FAERS
19GlaucomaFAERS: 3US FAERS
20Intentional drug misuseFAERS: 3OFFSIDES
US FAERS
21Muscle tightnessFAERS: 3SIDER
US FAERS
22PneumoniaFAERS: 3US FAERS
23Ventricular FibrillationFAERS: 3SIDER
US FAERS
24AgitationFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
25AnxietyFAERS: 2OFFSIDES
US FAERS
26Breast CystFAERS: 2OFFSIDES
US FAERS
27Congenital hydronephrosisFAERS: 2US FAERS
28DehydrationFAERS: 2US FAERS
29Double ureterFAERS: 2US FAERS
30DroolingFAERS: 2US FAERS
31Eating disorder symptomFAERS: 2US FAERS
32FatigueFAERS: 2US FAERS
33HepatitisFAERS: 2US FAERS
34MalaiseFAERS: 2US FAERS
35Neuroleptic Malignant SyndromeFAERS: 27234452CTD
OFFSIDES
SIDER
US FAERS
36Oropharyngeal painFAERS: 2US FAERS
37Pregnancy of partnerFAERS: 2US FAERS
38PregnancyFAERS: 2US FAERS
39Tardive DyskinesiaFAERS: 2SIDER
US FAERS
40Therapeutic response unexpectedFAERS: 2US FAERS
41Visual disturbanceFAERS: 2SIDER
US FAERS
42AkathisiaFAERS: 1SIDER
US FAERS
43AmnesiaFAERS: 1US FAERS
44AngerFAERS: 1US FAERS
45AngioedemaFAERS: 1US FAERS
46Atrial FibrillationFAERS: 1US FAERS
47Drug level increasedFAERS: 1US FAERS
48DysphoniaFAERS: 1US FAERS
49EnuresisFAERS: 16934699CTD
US FAERS
50Erectile dysfunctionFAERS: 17125001CTD
SIDER
US FAERS
51Escherichia sepsisFAERS: 1US FAERS
52Eye painFAERS: 1US FAERS
53HeadacheFAERS: 1SIDER
US FAERS
54Intentional self-injuryFAERS: 1US FAERS
55Lymphocyte count increasedFAERS: 1US FAERS
56Medication ErrorFAERS: 1US FAERS
57Monocyte count increasedFAERS: 1US FAERS
58Musculoskeletal stiffnessFAERS: 1OFFSIDES
US FAERS
59NauseaFAERS: 1SIDER
US FAERS
60Neutrophil count decreasedFAERS: 1US FAERS
61Obsessive-Compulsive DisorderFAERS: 1US FAERS
62OsteoporosisFAERS: 1US FAERS
63ParanoiaFAERS: 1US FAERS
64Pharyngolaryngeal PainFAERS: 1US FAERS
65Product quality issueFAERS: 1US FAERS
66Product substitution issueFAERS: 1US FAERS
67PyelonephritisFAERS: 1US FAERS
68RestlessnessFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
69Suicide attemptFAERS: 1US FAERS
70SyncopeFAERS: 1SIDER
US FAERS
71TachycardiaFAERS: 1SIDER
US FAERS
72Unresponsive to pain stimuliFAERS: 1US FAERS
73Unresponsive to stimuliFAERS: 1US FAERS
74VertigoFAERS: 1US FAERS
75VomitingFAERS: 1SIDER
US FAERS
76White blood cell count decreasedFAERS: 1US FAERS
77Abdominal discomfortSIDER
78AbuseOFFSIDES
79Adenocarcinoma9131265CTD
80AgranulocytosisSIDER
81AkinesiaSIDER
82AlveolitisOFFSIDES
83AmphetaminesOFFSIDES
84AnorexiaSIDER
85Application site painOFFSIDES
86AtherosclerosisOFFSIDES
87Basal Ganglia Diseases

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496555
6825122
8915564
11721647
 		CTD
88Blepharospasm3815152
9827620		CTD
OFFSIDES
89Blood creatine phosphokinase increasedOFFSIDES
90Blood prolactin increasedOFFSIDES
91Blood sodiumOFFSIDES
92Blood urea increasedOFFSIDES
93Bradycardia7391987
8448725
22744888		CTD
94BradykinesiaSIDER
95BronchitisOFFSIDES
96Catalepsy

View details

945050
1033567
1168927
1172422
1977408
8005645
 		CTD
97Cataplexy6976152CTD
98CataractSIDER
99Chemotherapeutic drug level increasedOFFSIDES
100Chest PainSIDER
101Circumstance or information capable of leading to medication errorOFFSIDES
102Cogwheel RigiditySIDER
103ConstipationSIDER
104Cor pulmonaleOFFSIDES
105Culture positiveOFFSIDES
106CyanosisOFFSIDES
107Depression suicidalOFFSIDES
108Depressive disorder1307220
6175138
9375593		CTD
109DermatitisSIDER
110Distress gastrointestinalSIDER
111DrowsinessOFFSIDES
SIDER
112Dyskinesia, Drug-Induced796855
1095689		CTD
113Dysthymic DisorderOFFSIDES
114Echocardiogram abnormalOFFSIDES
115Ejection Fraction DecreasedOFFSIDES
116Electrocardiogram U wave presentSIDER
117Electrocardiogram U-wave abnormalitySIDER
118Electrocardiogram abnormalSIDER
119Electrocardiogram changeSIDER
120Electrocardiogram repolarisation abnormalityOFFSIDES
121Electroencephalogram abnormalSIDER
122EnterocolitisOFFSIDES
123EosinophiliaSIDER
124Epidermal necrosisOFFSIDES
125EructationSIDER
126Escherichia infectionOFFSIDES
127Fatty LiverOFFSIDES
128Feeling abnormalCanada Vigilance: 1Canada Vigilance
129GalactorrheaOFFSIDES
130Gingival HyperplasiaSIDER
131HyperkeratosisOFFSIDES
132HyperkinesiaSIDER
133Hyperprolactinemia9131265CTD
134HyperpyrexiaSIDER
135HyperreflexiaSIDER
136Hypochondriasis6175138CTD
137Hypokinesia8750706CTD
138HypotensionSIDER
139HypoxiaOFFSIDES
140IncontinenceOFFSIDES
141Intention tremorOFFSIDES
142LethargyOFFSIDES
143LeukopeniaSIDER
144Long QT Syndrome

View details

10831018
16178046
24052561
25822712
 		CTD
145Mammary Neoplasms, Experimental9131265CTD
146Mental disorders796855
11721647
16856516		CTD
147Motor restlessnessSIDER
148Movement Disorders4607088CTD
149Muscle RigiditySIDER
150Musculoskeletal discomfortSIDER
151MyalgiaSIDER
152NocturiaSIDER
153Nuchal RigiditySIDER
154OculogyrationOFFSIDES
SIDER
155Oculogyric crisisSIDER
156OpisthotonusSIDER
157PCO2 decreasedOFFSIDES
158PalpitationsSIDER
159PancytopeniaSIDER
160Parkinsonian Disorders235013
4607088
6805002		CTD
161Pericardial effusionOFFSIDES
162Personality Disorders1168580CTD
163Polyuria1307220CTD
164PruritusSIDER
165Psychotic Disorders6175138
7211424		CTD
166Pulmonary congestionOFFSIDES
167Pulmonary thrombosisOFFSIDES
168Schizophrenia

View details

373996
1322069
6802100
6805002
9827620
 		CTD
SIDER
169Seizures

View details

6175290
6402945
7875556
8471829
15582832
17011125
 		CTD
170ShockSIDER
171Sialorrhea4607088CTD
172Skin irritationSIDER
173Spots before eyesSIDER
174SubileusOFFSIDES
175Substance-Related Disorders8750706
11325400		CTD
176SweatingSIDER
177Thrombocytopenic purpuraSIDER
178Torsades de Pointes16178046CTD
179TorticollisSIDER
180Troponin increasedOFFSIDES
181Ultrasound Doppler normalOFFSIDES
182Urinary RetentionSIDER
183UrticariaSIDER
184Visual ImpairmentSIDER
185Walking aid userCanada Vigilance: 1Canada Vigilance
186Weight GainOFFSIDES
187melanoma6825122CTD
188nervous system disorderSIDER
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