MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Fenfluramine

(DBGIVFWFUFKIQN-UHFFFAOYSA-N)

Structure

SMILES: CCNC(Cc1cccc(c1)C(F)(F)F)C
Type(s): Approved; Illicit; Investigational; Withdrawn
ATC code(s): A08AA02
Molecular Formula:: C12H16F3N
Molecular Weight:: 231.257
Log P:: 3.6368
Hydrogen Bond Acceptor:: 1
Hydrogen Bond Donor:: 1
TPSA:: 12.03
CAS Number(s):: 458-24-2; 16105-77-4

Synonym(s)

Fenfluramine

Fenfluramine Hydrochloride

Fenfluramine Hydrochloride, (+-)-Isomer

Fenfluramine Hydrochloride, R-Isomer

Fenfluramine, (+-)-Isomer

Fenfluramine, R-Isomer

Isomeride

Pondimin

Fenfluramine Hydrochloride, R Isomer

10.

Fenfluramine, R Isomer

11.

Hydrochloride, Fenfluramine

External Link(s)

MeSH	D005277
PubChem Compound	3337
BindingDB	84738
ChEBI	5000
CHEMBL	CHEMBL87493
DrugBank	DB00574
DrugCentral	1150
IUPHAR/BPS Guide to PHARMACOLOGY	4613
KEGG	cpd:C06996 dr:D07945
Therapeutic Target Database	D09WNK

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Abdominal Pain	Canada Vigilance: 2		Canada Vigilance
2	Anemia, Hemolytic		4706826	CTD
3	Anorexia		4118627	CTD
4	Anxiety Disorders		8545621	CTD
5	Aortic Valve Insufficiency		View details 9280830 9385873 9437392 9731086 9731087 9867728 10440587 10533670 10533956 10593346 10614800 10755496 10790349 10807073 10867106 11171493 11182835 11581595 11735689 12050608 12079711 12194699 12486432 12686663 12801402 17383382 17626991 18990200	CTD
6	Autistic Disorder		2606882 3709993 6502317	CTD
7	Bipolar Disorder		9714271	CTD
8	Bradycardia		9477076	CTD
9	Bruxism		4326288	CTD
10	Cardiomyopathies		4055256	CTD
11	Catalepsy		2972934 8386235	CTD
12	Catatonia		8887967	CTD
13	Cerebral Hemorrhage		9270617	CTD
14	Chemical and Drug Induced Liver Injury		10469626	CTD
15	Cocaine-Related Disorders		9598218 9668665 17071819	CTD
16	Confusion		5354861	CTD
17	Depressive disorder		View details 4414229 4895336 5039550 5073787 5440606 5460561 8545621	CTD
18	Diarrhea		4895336	CTD
19	Dizziness		6753613	CTD
20	Dyskinesia, Drug-Induced		4847362 5354861 6493634	CTD
21	Endomyocardial Fibrosis		9565497	CTD
22	Fatigue		6753613	CTD
23	Feeding and Eating Disorders		8223940	CTD
24	Fever		2889795 4048012	CTD
25	Growth Disorders		10469626	CTD
26	Hallucinations		4414229	CTD
27	Headache	Canada Vigilance: 1	5354861	CTD Canada Vigilance
28	Heart Diseases		848709 9818470	CTD
29	Heart failure		2376256 11581595	CTD
30	Hyperprolactinemia		1678730	CTD
31	Hypotension		9477076	CTD
32	Hypoxia		2367283	CTD
33	Insulin Resistance		10574509	CTD
34	Lethargy		4895336	CTD
35	Mitral Valve Insufficiency		View details 9280830 9385873 9437392 9731086 9731087 10320298 10391313 10440587 10533956 10614800 10790349 10807073 10867106 11171493 11182835 11581595 11735689 12050608 12194699 12486432 12801402 17383382 17626991 18990200	CTD
36	Mood Disorders		3709993	CTD
37	Movement Disorders		16817869	CTD
38	Nausea		5354861	CTD
39	Obesity		View details 1124579 1233823 4118627 4119946 4414229 4895336 5039550 5460561 6130379 6753613 9183245 9270617 9688104 10440587 10509604 10574509 12357124 17146452	CTD
40	Pain		8446441	CTD
41	Panic Disorder		9361714	CTD
42	Personality Disorders		7197574	CTD
43	Precancerous Conditions		10469626	CTD
44	Psychoses, Substance-Induced		4414229 5354861 5440606	CTD
45	Pulmonary Edema		8681646	CTD
46	Pulmonary Valve Insufficiency		View details 1754534 9280830 11182835 17626991	CTD
47	Schizophrenia		4414229	CTD
48	Seizures		1116545	CTD
49	Sleep Initiation and Maintenance Disorders		3308829	CTD
50	Sleep Wake Disorders		4326288	CTD
51	Status Epilepticus		7667346	CTD
52	Substance Withdrawal Syndrome		5073787 5460561	CTD
53	Tachycardia	Canada Vigilance: 1		Canada Vigilance
54	Tricuspid Valve Insufficiency		View details 1754534 9280830 11171493 11182835 11581595 11834685 17626991 18990200	CTD
55	Vascular Diseases		10383810	CTD
56	Xerostomia		6753613	CTD

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