MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leprosy, Lepromatous

(UMLS:C0023348)

Definition:: A chronic communicable infection which is a principal or polar form of LEPROSY. This disorder is caused by MYCOBACTERIUM LEPRAE and produces diffuse granulomatous skin lesions in the form of nodules, macules, or papules. The peripheral nerves are involved symmetrically and neural sequelae occur in the advanced stage.
UMLS ID:: C0023348
MeSH ID:: D015440

Classification:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.410.040.552.386.775.500

Synonym(s)

Leprosy, Lepromatous

Full lepromatous leprosy

HANSEN DISEASE, MALIGNANT FORM

LEPROMATOUS LEPROSY

LL - Full lepromatous leprosy

LL; leprosy

Lepromatous leprosy

Lepromatous leprosy [type L]

Type L leprosy

10.

Type LL leprosy

11.

lepromatous leprosy

12.

lepromatous; leprosy

13.

leprosy; LL

14.

leprosy; lepromatous

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Clofazimine	16038251 16638414	CTD
2	Dapsone	6991816 16038251 16638414	CTD
3	Ethionamide	4261347	CTD
4	Ofloxacin	14996384	CTD
5	Prednisolone	16638414	CTD
6	Prednisone	19663116	CTD
7	Rifampin	View details 6549453 6991816 14996384 16038251 16638414	CTD
8	Thalidomide	7005131 9623511 19663116	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Mycobacterium Infections, Nontuberculous	30.6%
2	Tuberculosis	30.6%
3	Mycobacterium abscessus Infection	30.6%
4	Actinomycosis	26.8%
5	Corynebacterium Infections	26.8%
6	Nocardia Infections	26.8%
7	Pulmonary Nocardiosis	26.8%
8	Borderline leprosy	24.7%
9	Tuberculoid leprosy	24.7%
10	Clostridium Infections	24%
11	Listeriosis	24%
12	Staphylococcal Infections	24%
13	Streptococcal Infections	24%
14	Bacillaceae Infections	24%
15	Clostridium difficile infection	24%
16	Gram-Negative Bacterial Infections	20.7%
17	Mycobacterium avium-intracellulare Infection	18.3%
18	Lymph Node Tuberculosis	18.3%
19	Tuberculosis, Miliary	18.3%
20	Tuberculosis, Multidrug-Resistant	18.3%
21	Latent Tuberculosis	18.3%
22	Erysipelothrix infection	17.3%
23	Diphtheria	14.8%
24	Mycoses	14.5%
25	Infection	14.5%
26	Central Nervous System Bacterial Infections	14%
27	Borrelia Infections	13.9%
28	Leptospirosis	13.9%
29	Bacterial Vaginosis	13.5%
30	Tuberculosis, Gastrointestinal	12.7%
31	Gas Gangrene	12.5%
32	Pneumococcal Infections	12.5%
33	Scarlet Fever	12.5%
34	Tetanus	12.5%
35	Tuberculosis, Central Nervous System	12.3%
36	Extensively Drug-Resistant Tuberculosis	12.2%
37	Skin Diseases, Bacterial	12.1%
38	Bacteremia	11.9%
39	Joint Tuberculosis	11.1%
40	Tuberculosis, Osteoarticular	11.1%
41	Bone Tuberculosis	11.1%
42	Erythrasma	10.9%
43	Pneumonia, Bacterial	10.3%
44	Bordetella Infections	10.3%
45	Brucellosis	10.3%
46	Campylobacter infection	10.3%
47	Enterobacteriaceae Infections	10.3%
48	Pseudomonas Infections	10.3%
49	Q Fever	10.3%
50	Vibrio Infections	10.3%
51	Helicobacter Infections	10.3%
52	Neisseriaceae Infections	10.3%
53	Burkholderia Infections	10.3%
54	Flavobacteriaceae Infections	10.3%
55	Moraxellaceae Infections	10.3%
56	Burkholderia cepacia Infection	10.3%
57	Erysipelas	9.9%
58	Staphylococcal Skin Infections	9.9%
59	Bacterial Endocarditis	9.8%
60	Tuberculosis, Pulmonary	9.7%
61	Central Nervous System Infection	9.7%
62	Impetigo	8.6%
63	Ecthyma	8.3%
64	Subacute Bacterial Endocarditis	8.3%
65	Mycetoma	8.1%
66	Lyme Disease	8.1%
67	Relapsing Fever	8.1%
68	Meningitis, Listeria	7.2%
69	Human Ehrlichiosis	7.2%
70	Aspergillosis	6.9%
71	Candidiasis	6.9%
72	Coccidioidomycosis	6.9%
73	Histoplasmosis	6.9%
74	Paracoccidioidomycosis	6.9%
75	Pelvic Infection	6.9%
76	Wound Infection	6.9%
77	Zygomycosis	6.9%
78	Soft Tissue Infection	6.9%
79	Community-Acquired Infections	6.9%
80	Phaeohyphomycosis	6.9%
81	Pneumocystis Infections	6.9%
82	Syphilis	6.6%
83	Rheumatic Fever	6.5%
84	Neurosyphilis	6.5%
85	Lyme Neuroborreliosis	6.4%
86	Enterocolitis, Pseudomembranous	6.3%
87	pseudomembranous colitis	6.3%
88	Tuberculosis, Meningeal	5.9%
89	Chlamydia Infections	5.8%
90	Gonorrhea	5.8%
91	Human anaplasmosis	5.7%
92	Tuberculosis, Spinal	5.7%
93	Japanese Spotted Fever	5.6%
94	Acinetobacter Infections	5.4%
95	Bacteroides Infections	5.4%
96	Cholera	5.4%
97	Escherichia coli Infections	5.4%
98	Haemophilus Infections	5.4%
99	Klebsiella Infections	5.4%
100	Meningococcal Infections	5.4%
101	Mycoplasma Infections	5.4%
102	Pasteurella Infections	5.4%
103	Proteus Infections	5.4%
104	Rickettsia Infections	5.4%
105	Salmonella infections	5.4%
106	Scrub Typhus	5.4%
107	Serratia Infections	5.4%
108	Ureaplasma Infections	5.4%
109	Staphylococcal Scalded Skin Syndrome	5.3%
110	Erythema Chronicum Migrans	5.3%
111	Botulism	5.2%
112	Dermatomycoses	5.2%
113	Hidradenitis Suppurativa	5.2%
114	Meningitis, Bacterial	5.2%
115	Hordeolum	5%
116	Meningitis, Pneumococcal	4.9%
117	Eye Infection	4.9%
118	Respiratory Tract Infections	4.9%
119	Bacterial conjunctivitis	4.9%
120	Ulcerative stomatitis	4.9%
121	Rheumatic Heart Disease	4.8%
122	Erythema Induratum	4.7%
123	Bone Diseases, Infectious	4.7%
124	Otomycosis	4.7%
125	Pregnancy Complications, Infectious	4.7%
126	Skin Diseases, Infectious	4.7%
127	Arthritis, Infectious	4.6%
128	Piedra	4.6%
129	Central Nervous System Fungal Infections	4.6%
130	Suppuration	4.6%
131	Pertussis	4.6%
132	Cross Infection	4.5%
133	Septicemia	4.5%
134	Sepsis	4.5%
135	Furunculosis	4.5%
136	furuncle	4.5%
137	Tuberculosis, Renal	4.2%
138	Rhinoscleroma	3.9%
139	Opportunistic Infections	3.8%
140	Lung Diseases, Fungal	3.6%
141	Urinary tract infection	3.5%
142	Candidiasis, Chronic Mucocutaneous	3.5%
143	Cutaneous Candidiasis	3.5%
144	Brain Abscess	3.5%
145	Neuroaspergillosis	3.5%
146	Fungemia	3.4%
147	Mucormycosis	3.4%
148	Meningitis, Haemophilus	3.3%
149	Rocky Mountain Spotted Fever	3.2%
150	Lymphogranuloma Venereum	3.1%
151	carbuncle	3.1%
152	Syphilis, Congenital	3.1%
153	Psittacosis	3%
154	Paratyphoid Fever	3%
155	Plague	3%
156	Typhoid Fever	3%
157	TYPHUS	3%
158	Yersinia pseudotuberculosis Infections	3%
159	Bubonic Plague	3%
160	Sexually Transmitted Diseases	2.9%
161	Cellulitis	2.8%
162	Ophthalmia Neonatorum	2.7%
163	Trachoma	2.7%
164	Dysentery, Bacillary	2.7%
165	Chromoblastomycosis	2.6%
166	Dermatophytosis	2.6%
167	Sporotrichosis	2.6%
168	Tinea	2.6%
169	Tinea Versicolor	2.6%
170	Trichophytosis	2.6%
171	Invasive Pulmonary Aspergillosis	2.6%
172	Hyalohyphomycosis	2.6%
173	Endotoxemia	2.6%
174	Blastomycosis	2.5%
175	Candidemia	2.4%
176	Oral candidiasis	2.4%
177	Endophthalmitis	2.4%
178	Peritonitis	2.4%
179	Osteomyelitis	2.3%
180	Periostitis	2.3%
181	Surgical Wound Infection	2.3%
182	Pulmonary Aspergillosis	2.3%
183	Bronchopulmonary Aspergillosis	2.3%
184	Panophthalmitis	2.3%
185	Abscess	2.3%
186	Adnexitis	2.3%
187	Empyema	2.3%
188	Pelvic Inflammatory Disease	2.3%
189	Salmonella Infections, Animal	2.1%
190	Meningitis, Cryptococcal	2.1%
191	Salmonella food poisoning	2%
192	Superinfection	1.8%
193	Psoas Abscess	1.8%
194	Abdominal Abscess	1.8%
195	Corneal Ulcer	1.8%
196	Puerperal Infection	1.7%
197	Spondylitis	1.7%
198	Appendicitis	1.7%
199	Bacteriuria	1.7%
200	Pyuria	1.7%
201	Meningitis, Fungal	1.7%
202	Pyomyositis	1.7%
203	Endotoxic shock	1.7%
204	Septic Shock	1.7%
205	Toxic Shock Syndrome	1.7%
206	Candidiasis, Vulvovaginal	1.7%
207	Fusariosis	1.4%
208	Arthritis, Reactive	1.4%
209	Diverticulitis	1.2%
210	AIDS-Related Opportunistic Infections	1.2%
211	Tinea Capitis	1.1%
212	Onychomycosis	1.1%
213	Toxoplasmosis, Cerebral	1.1%
214	Waterhouse-Friderichsen Syndrome	1%
215	Lung Abscess	0.9%
216	Tinea Pedis	0.9%
217	Diverticulum	0.9%
218	Diverticulosis	0.9%
219	Discitis	0.9%
220	Mastoiditis	0.9%
221	Petrositis	0.9%
222	Lemierre Syndrome	0.9%
223	Retropharyngeal Abscess	0.7%
224	Epidural Abscess	0.7%
225	Peritonsillar Abscess	0.7%
226	Liver Abscess	0.7%
227	Aspergillosis, Allergic Bronchopulmonary	0.6%
228	Liver Abscess, Amebic	0.2%

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