MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Toxic Shock Syndrome

(UMLS:C0600327)

UMLS ID:: C0600327
MeSH ID:: D012772

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.539.757.800

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.470.790.500.800|C23.550.835.900.712

Synonym(s)

Toxic Shock Syndrome

Gram-positive septic shock

Shock Syndrome (TSS), Toxic

Syndrome (TSS), Toxic Shock

TOXIC SHOCK SYNDROME

TOXIC-SHOCK SYNDROME

TSS

TSS - Toxic shock syndrome

TSS, Toxic Shock Syndrome

10.

Toxic Shock Syndrome, (TSS)

11.

Toxic shock syndrome

12.

shock syndrome; toxic

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Norgestrel	FAERS: 22 Canada Vigilance: 1	Canada Vigilance US FAERS
2	NuvaRing	FAERS: 21 Canada Vigilance: 1	Canada Vigilance US FAERS
3	Clindamycin	FAERS: 6	US FAERS
4	ziprasidone	FAERS: 6	US FAERS
5	Lamotrigine	FAERS: 5	US FAERS
6	Sildenafil Citrate	FAERS: 5	US FAERS
7	Propofol	FAERS: 4	US FAERS
8	Acetaminophen	FAERS: 3	US FAERS
9	Lenalidomide	FAERS: 3 Canada Vigilance: 1	Canada Vigilance US FAERS
10	Bosentan	FAERS: 2	US FAERS
11	Dabigatran	FAERS: 2	US FAERS
12	Deferasirox	FAERS: 2	US FAERS
13	Estradiol	FAERS: 2	SIDER US FAERS
14	Estriol	FAERS: 2	US FAERS
15	Fingolimod Hydrochloride	FAERS: 2	US FAERS
16	Glatiramer Acetate	FAERS: 2	US FAERS
17	Linezolid	FAERS: 2	US FAERS
18	Misoprostol	FAERS: 2	US FAERS
19	Ortho Evra	FAERS: 2	US FAERS
20	Oseltamivir	FAERS: 2	US FAERS
21	Sulfamethoxazole	FAERS: 2	US FAERS
22	Sunitinib	FAERS: 2	US FAERS
23	abacavir	FAERS: 2	US FAERS
24	beyaz	FAERS: 2	US FAERS
25	cabozantinib	FAERS: 2	US FAERS
26	tofacitinib	FAERS: 2	US FAERS
27	valdecoxib	FAERS: 2	US FAERS
28	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride	FAERS: 1	US FAERS
29	4-hydroxybutyric acid	FAERS: 1	US FAERS
30	8-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro(4,5)decan-2-one	FAERS: 1	US FAERS
31	Adzenys XR-ODT	FAERS: 1	US FAERS
32	Amlodipine	FAERS: 1	US FAERS
33	Carbamazepine	FAERS: 1	US FAERS
34	Clomiphene	FAERS: 1	US FAERS
35	Clonidine	FAERS: 1	US FAERS
36	Clopidogrel	FAERS: 1	US FAERS
37	Clotrimazole	FAERS: 1	US FAERS
38	Clozapine	FAERS: 1	US FAERS
39	Copper	FAERS: 1	US FAERS
40	Crizotinib	FAERS: 1	US FAERS
41	Diclofenac	FAERS: 1	SIDER US FAERS
42	Digoxin	FAERS: 1	US FAERS
43	Doxycycline	FAERS: 1	US FAERS
44	Exenatide	FAERS: 1	US FAERS
45	Ibuprofen	FAERS: 1	US FAERS
46	Imatinib Mesylate	FAERS: 1	US FAERS
47	Imatinib Mesylate	FAERS: 1	US FAERS
48	Isotretinoin	FAERS: 1	US FAERS
49	Levofloxacin	FAERS: 1	US FAERS
50	MDV 3100	FAERS: 1	US FAERS
51	Metronidazole	FAERS: 1	US FAERS
52	Mifepristone	FAERS: 1	SIDER US FAERS
53	Minoxidil	FAERS: 1	US FAERS
54	Modafinil	FAERS: 1	US FAERS
55	Mycophenolic Acid	FAERS: 1	US FAERS
56	Nitroxyl	FAERS: 1	US FAERS
57	Olanzapine	FAERS: 1	US FAERS
58	Pemetrexed	FAERS: 1	US FAERS
59	Pregabalin	FAERS: 1	US FAERS
60	Ranitidine	FAERS: 1	US FAERS
61	Risedronic Acid	FAERS: 1	US FAERS
62	Sildenafil Citrate	FAERS: 1	US FAERS
63	Sirolimus	FAERS: 1	US FAERS
64	Teriparatide	FAERS: 1	US FAERS
65	Tetracycline	FAERS: 1	US FAERS
66	Thalidomide	FAERS: 1	US FAERS
67	Vincristine	FAERS: 1	US FAERS
68	macitentan	FAERS: 1	US FAERS
69	palbociclib	FAERS: 1	US FAERS
70	pirfenidone	FAERS: 1	US FAERS
71	reviparin	FAERS: 1	US FAERS
72	treprostinil	FAERS: 1	US FAERS
73	Thiotepa		SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Bacteremia	38.2%
2	Fungemia	36.7%
3	Endotoxemia	32.4%
4	Suppuration	29.6%
5	Shock, Hemorrhagic	29.5%
6	Polydipsia	25.6%
7	Viremia	24%
8	Parasitemia	24%
9	Ascites	23.7%
10	Fibrosis	23.7%
11	Gliosis	23.7%
12	Growth Disorders	23.7%
13	Hemorrhage	23.7%
14	Hyperbilirubinemia	23.7%
15	Hyperplasia	23.7%
16	Hypomenorrhea	23.7%
17	Intraoperative Complications	23.7%
18	Ischemia	23.7%
19	Lithiasis	23.7%
20	Malacoplakia	23.7%
21	Menstruation Disturbances	23.7%
22	Metaplasia	23.7%
23	Nerve Degeneration	23.7%
24	Ochronosis	23.7%
25	Polymenorrhea	23.7%
26	Postoperative Complications	23.7%
27	Sclerosis	23.7%
28	Ulcer	23.7%
29	Hyperammonemia	23.7%
30	Hyperamylasemia	23.7%
31	Teratogenesis	23.7%
32	Cardiac Death	23.7%
33	Hypovolemia	23.7%
34	Hyperuricemia	23.7%
35	Leukoaraiosis	23.7%
36	Dysbacteriosis	23.7%
37	Delayed Graft Function	23.7%
38	Cirrhosis	23.7%
39	Neointima	23.7%
40	Dysbiosis	23.7%
41	Multiple Organ Failure	23.3%
42	Candidemia	23%
43	Infarction	21.6%
44	Postoperative Hemorrhage	21.6%
45	Acute-Phase Reaction	21.6%
46	Serositis	21.6%
47	Seroma	21.6%
48	Vascular Remodeling	21.5%
49	Extravasation of Diagnostic and Therapeutic Materials	19.7%
50	Neoplastic Processes	19.7%
51	Shock, Traumatic	19.5%
52	Necrosis	19.2%
53	Granulomatosis, Orofacial	19.2%
54	Pigmentation Disorders	19.2%
55	Respiratory Aspiration	19.2%
56	Cellulitis	19.1%
57	Acantholysis	18.9%
58	Chromosome Aberrations	18.9%
59	Dehydration	18.9%
60	Granuloma	18.9%
61	Leukocytosis	18.9%
62	Pleocytosis	18.9%
63	Cross Infection	18.8%
64	Surgical Wound Infection	18.7%
65	Abscess	18.6%
66	Empyema	18.6%
67	Foreign-Body Reaction	17.6%
68	Neurogenic Inflammation	17.6%
69	Genomic Instability	16.3%
70	Chromosomal Instability	15.6%
71	Azotemia	15.6%
72	Shock, Cardiogenic	15.4%
73	Muscle Weakness	15.3%
74	Signs and Symptoms	15%
75	Pathological Conditions, Anatomical	15%
76	Pelvic Infection	14.9%
77	Wound Infection	14.9%
78	Soft Tissue Infection	14.9%
79	Community-Acquired Infections	14.9%
80	Menorrhagia	14.6%
81	Incisional hernia	14.4%
82	jaundice	14.4%
83	Cardiotoxicity	13.7%
84	Sudden infant death syndrome	13.6%
85	Acute Disease	13.5%
86	Amenorrhea	13.5%
87	Chronic disease	13.5%
88	Critical Illness	13.5%
89	Sudden death	13.5%
90	Fat necrosis	13.5%
91	Gangrene	13.5%
92	Graft Occlusion, Vascular	13.5%
93	Granuloma, Plasma Cell	13.5%
94	Hematoma	13.5%
95	Iatrogenic Disease	13.5%
96	Oligomenorrhea	13.5%
97	Premenstrual syndrome	13.5%
98	Recurrence	13.5%
99	Retrograde Degeneration	13.5%
100	Retroperitoneal fibrosis	13.5%
101	Subcutaneous Emphysema	13.5%
102	Surgical Wound Dehiscence	13.5%
103	Syndrome	13.5%
104	Wallerian Degeneration	13.5%
105	Pyogenic granuloma	13.5%
106	Exsanguination	13.5%
107	Disease Progression	13.5%
108	Premenstrual Tension	13.5%
109	Delayed Emergence from Anesthesia	13.5%
110	Infant Death	13.5%
111	Anastomotic Leak	13.5%
112	Intraoperative Awareness	13.5%
113	Pain, Postoperative	13%
114	Postoperative Nausea and Vomiting	12.7%
115	Eye Hemorrhage	12.5%
116	Eye Infection	12.5%
117	Respiratory Tract Infections	12.5%
118	Inflammation	12.4%
119	Dysmenorrhea	12.3%
120	Failed Back Surgery Syndrome	12.3%
121	Hemoptysis	12.2%
122	Bone Diseases, Infectious	12.1%
123	Pregnancy Complications, Infectious	12.1%
124	Skin Diseases, Infectious	12.1%
125	Ecchymosis	12.1%
126	Petechiae	12.1%
127	Purpura	12.1%
128	Arthritis, Infectious	12%
129	Asphyxia	11.3%
130	Granuloma, Respiratory Tract	11.3%
131	Shock	11.2%
132	Ulcerative stomatitis	11.2%
133	Disease susceptibility	11%
134	Fetal Death	11%
135	Gastrointestinal Hemorrhage	11%
136	Hemarthrosis	11%
137	Hemoperitoneum	11%
138	Hemothorax	11%
139	Neoplasm Invasiveness	11%
140	Neoplasm Metastasis	11%
141	Neoplasm Recurrence, Local	11%
142	Postpericardiotomy Syndrome	11%
143	Prosthesis Failure	11%
144	Reperfusion Injury	11%
145	Injection Site Reaction	11%
146	Retrobulbar Hemorrhage	11%
147	Aseptic Necrosis of Bone	11%
148	Peritoneal Fibrosis	11%
149	Carcinogenesis	11%
150	Perinatal death	11%
151	Infusion site reaction	11%
152	Nephrogenic Fibrosing Dermopathy	11%
153	Corneal Endothelial Cell Loss	11%
154	Encapsulating Peritoneal Sclerosis	11%
155	Vasoplegia	11%
156	Nephrogenic Systemic Fibrosis	11%
157	Metastasis	11%
158	Sinus Arrhythmia	10.8%
159	Atrial Fibrillation	10.8%
160	Atrial Flutter	10.8%
161	Dental Pulp Necrosis	10.8%
162	Granuloma, Foreign-Body	10.8%
163	Mediastinal Emphysema	10.8%
164	Ventricular Fibrillation	10.8%
165	Ventricular Flutter	10.8%
166	Parasystole	10.8%
167	Paroxysmal atrial fibrillation	10.8%
168	Systemic Inflammatory Response Syndrome	10.8%
169	Facies	10.8%
170	Bradycardia	10.8%
171	Embryo Loss	10.8%
172	Afferent Loop Syndrome	10.7%
173	Sex Chromosome Aberrations	10.7%
174	Short Bowel Syndrome	10.7%
175	Uterine hemorrhage	10.7%
176	No-Reflow Phenomenon	10.7%
177	Opportunistic Infections	10.7%
178	Epistaxis	10.6%
179	Hidradenitis Suppurativa	10.2%
180	Diverticulum	10.1%
181	Diverticulosis	10.1%
182	Urinary tract infection	10.1%
183	Dermatomycoses	10%
184	Skin Diseases, Bacterial	10%
185	Chromosome Fragility	9.7%
186	Drowning	9.3%
187	Mycetoma	9.3%
188	Fetal Growth Retardation	9.1%
189	DNA Degradation, Necrotic	9.1%
190	Aneuploidy	9.1%
191	Polyploidy	9.1%
192	Microsatellite Instability	9.1%
193	Jaundice, Obstructive	9.1%
194	Heart Block	9%
195	Tachycardia	9%
196	Tachyarrhythmia	9%
197	Cicatrix	9%
198	Hematuria	9%
199	Granuloma Annulare	9%
200	Chromosome Breakage	9%
201	Brain Death	9%
202	Sexually Transmitted Diseases	8.9%
203	Bacterial Endocarditis	8.6%
204	Bacterial Infections	8.6%
205	Mycoses	8.6%
206	Tissue Adhesions	8.5%
207	Hematoma, Epidural, Spinal	8.5%
208	Sick Sinus Syndrome	8.5%
209	Trisomy	8.5%
210	Pertussis	8.3%
211	Endophthalmitis	8%
212	Peritonitis	8%
213	Candidiasis, Chronic Mucocutaneous	7.9%
214	Cutaneous Candidiasis	7.9%
215	Asthenia	7.9%
216	Body Temperature Changes	7.9%
217	Calculi	7.9%
218	Cyanosis	7.9%
219	Edema	7.9%
220	Failure to Thrive	7.9%
221	Fatigue	7.9%
222	Feminization	7.9%
223	Fetal Distress	7.9%
224	Hernia	7.9%
225	Hypertrophy	7.9%
226	Motion Sickness	7.9%
227	Nails, Malformed	7.9%
228	polyps	7.9%
229	Rupture, Spontaneous	7.9%
230	Signs and Symptoms, Digestive	7.9%
231	Signs and Symptoms, Respiratory	7.9%
232	Skin Manifestations	7.9%
233	Chills	7.9%
234	Lassitude	7.9%
235	Enterocele	7.9%
236	Atheroma	7.9%
237	Pseudophakia	7.9%
238	Urological Manifestations	7.9%
239	Stenosis	7.9%
240	Facial asymmetry	7.9%
241	Mobility Limitation	7.9%
242	Somnolence	7.9%
243	Plaque, Amyloid	7.9%
244	Plaque, Atherosclerotic	7.9%
245	Giant Cell Epulis	7.9%
246	Osteomyelitis	7.9%
247	Periostitis	7.9%
248	Adnexitis	7.8%
249	Pelvic Inflammatory Disease	7.8%
250	Joint Tuberculosis	7.7%
251	Tuberculosis, Osteoarticular	7.7%
252	Bone Tuberculosis	7.7%
253	Long QT Syndrome	7.7%
254	Micronuclei, Chromosome-Defective	7.6%
255	Hematemesis	7.6%
256	Purpura Fulminans	7.5%
257	Hematoma, Subdural	7.5%
258	Hematoma, Epidural, Cranial	7.5%
259	Erysipelas	7.4%
260	Staphylococcal Skin Infections	7.4%
261	Psoas Abscess	7.3%
262	Abdominal Abscess	7.3%
263	Erythrasma	7.2%
264	Brain Abscess	7.1%
265	Chromoblastomycosis	7%
266	Dermatophytosis	7%
267	Sporotrichosis	7%
268	Tinea	7%
269	Tinea Versicolor	7%
270	Trichophytosis	7%
271	Hyalohyphomycosis	7%
272	Hyphema	6.9%
273	Retinal Neovascularization	6.9%
274	Vitreous Hemorrhage	6.9%
275	Central Nervous System Infection	6.9%
276	Subacute Combined Degeneration	6.9%
277	Femur Head Necrosis	6.8%
278	Fetal Resorption	6.8%
279	Lymphatic Metastasis	6.8%
280	Neoplasms, Unknown Primary	6.8%
281	Peptic Ulcer Hemorrhage	6.8%
282	Sudden Cardiac Death	6.8%
283	Leukemic Infiltration	6.8%
284	Premenstrual Dysphoric Disorder	6.8%
285	Choroidal Neovascularization	6.8%
286	Primary Graft Dysfunction	6.8%
287	Neoplasm Micrometastasis	6.8%
288	Syphilis	6.8%
289	Dumping Syndrome	6.8%
290	Cicatrix, Hypertrophic	6.8%
291	Sinus Arrest, Cardiac	6.8%
292	Eosinophilic Granuloma	6.8%
293	Metrorrhagia	6.8%
294	Panophthalmitis	6.8%
295	Superinfection	6.7%
296	Central Nervous System Bacterial Infections	6.7%
297	Corneal Ulcer	6.6%
298	Erythema Chronicum Migrans	6.6%
299	Puerperal Infection	6.6%
300	Spondylitis	6.6%
301	Cyst	6.6%
302	Eye Manifestations	6.6%
303	Neurologic Manifestations	6.6%
304	Appendicitis	6.5%
305	Bacteriuria	6.5%
306	Pyuria	6.5%
307	Pyomyositis	6.5%
308	Ecthyma	6.5%
309	Subacute Bacterial Endocarditis	6.5%
310	Chlamydia Infections	6.5%
311	Gonorrhea	6.5%
312	Impetigo	6.4%
313	Leukoplakia	6.4%
314	Cardiac Output, High	6.4%
315	Myocardial Stunning	6.4%
316	Reticulocytosis	6.4%
317	Low Cardiac Output Syndrome	6.4%
318	Airway Remodeling	6.4%
319	Ventricular Remodeling	6.3%
320	Alopecia	6.3%
321	Intermittent Claudication	6.3%
322	Androgenetic Alopecia	6.3%
323	Phantom pain	6.3%
324	Phantom Limb Pain	6.3%
325	Blastomycosis	6.2%
326	Hordeolum	6.1%
327	Bacterial conjunctivitis	6.1%
328	Renal Colic	6.1%
329	Kernicterus	6.1%
330	Hematoma, Subdural, Spinal	6%
331	Staphylococcal Scalded Skin Syndrome	6%
332	Abdominal Pain	5.9%
333	Retinal Hemorrhage	5.8%
334	Diverticulitis	5.8%
335	Thrombocytopenic purpura	5.8%
336	Choroid Hemorrhage	5.8%
337	Melena	5.8%
338	Postpartum Hemorrhage	5.7%
339	Gingival Hemorrhage	5.7%
340	Keloid	5.7%
341	Purpura, Hyperglobulinemic	5.7%
342	Monosomy	5.7%
343	Tetraploidy	5.7%
344	Stillbirth	5.7%
345	Adams-Stokes Syndrome	5.7%
346	Atrioventricular Block	5.7%
347	Bundle-Branch Block	5.7%
348	Atrial Premature Complexes	5.7%
349	Sinoatrial Block	5.7%
350	Tachycardia, Paroxysmal	5.7%
351	Supraventricular tachycardia	5.7%
352	Tachycardia, Ventricular	5.7%
353	Tachycardia, Reciprocating	5.7%
354	Subarachnoid Hemorrhage	5.6%
355	Cerebral Hemorrhage	5.6%
356	Tinea Pedis	5.6%
357	Fusariosis	5.6%
358	Arthritis, Reactive	5.5%
359	Hypergammaglobulinemia	5.3%
360	Hematoma, Subdural, Intracranial	5.3%
361	Hematoma, Subdural, Chronic	5.3%
362	Hematoma, Subdural, Acute	5.3%
363	Furunculosis	5.3%
364	furuncle	5.3%
365	Borrelia Infections	5.2%
366	Leptospirosis	5.2%
367	carbuncle	5.2%
368	Lymphogranuloma Venereum	5.2%
369	Rhinoscleroma	5.2%
370	Tuberculosis, Spinal	5.1%
371	Waterhouse-Friderichsen Syndrome	5%
372	Lung Abscess	5%
373	AIDS-Related Opportunistic Infections	5%
374	Aspergillosis	5%
375	Candidiasis	5%
376	Coccidioidomycosis	5%
377	Histoplasmosis	5%
378	Paracoccidioidomycosis	5%
379	Zygomycosis	5%
380	Gram-Negative Bacterial Infections	5%
381	Gram-Positive Bacterial Infections	5%
382	Phaeohyphomycosis	5%
383	Pneumocystis Infections	5%
384	Eye pain	5%
385	Liver Abscess	4.9%
386	Muscular Atrophy	4.9%
387	Endotoxic shock	4.9%
388	Septic Shock	4.9%
389	Toxic Shock Syndrome	4.9%
390	Discitis	4.9%
391	Lyme Disease	4.9%
392	Mastoiditis	4.9%
393	Relapsing Fever	4.9%
394	Petrositis	4.9%
395	Tinea Capitis	4.8%
396	Onychomycosis	4.8%
397	Romano-Ward Syndrome	4.8%
398	Ophthalmia Neonatorum	4.7%
399	Trachoma	4.7%
400	Lyme Neuroborreliosis	4.6%
401	Anorexia	4.5%
402	Anoxia	4.5%
403	Constipation	4.5%
404	Diarrhea	4.5%
405	Dyspepsia	4.5%
406	Eructation	4.5%
407	Fever	4.5%
408	Flatulence	4.5%
409	Flushing	4.5%
410	Halitosis	4.5%
411	Heartburn	4.5%
412	Diaphragmatic Hernia	4.5%
413	Hiccough	4.5%
414	Hypercalciuria	4.5%
415	Hypercapnia	4.5%
416	Hyperphagia	4.5%
417	Intestinal Polyps	4.5%
418	Nausea	4.5%
419	Pallor	4.5%
420	Psychophysiologic Disorders	4.5%
421	Splenomegaly	4.5%
422	Vomiting	4.5%
423	Hypocapnia	4.5%
424	Dyschezia	4.5%
425	Hypoxia	4.5%
426	Hyperoxia	4.5%
427	Lower Urinary Tract Symptoms	4.5%
428	Hypoxemia	4.5%
429	Urinoma	4.5%
430	Granuloma, Laryngeal	4.4%
431	Neuroaspergillosis	4.4%
432	Myocardial Reperfusion Injury	4.3%
433	Retropharyngeal Abscess	4.2%
434	Epidural Abscess	4.2%
435	Neurosyphilis	4.2%
436	Peritonsillar Abscess	4.2%
437	Cell Transformation, Viral	4.1%
438	Erythema Induratum	4.1%
439	Otomycosis	4%
440	Purpura, Thrombotic Thrombocytopenic	4%
441	Tachycardia, Atrioventricular Nodal Reentry	4%
442	Tachycardia, Ectopic Atrial	4%
443	Tachycardia, Ectopic Junctional	4%
444	Sinus Tachycardia	4%
445	Torsades de Pointes	4%
446	Accelerated Idioventricular Rhythm	4%
447	Piedra	4%
448	Central Nervous System Fungal Infections	4%
449	Septicemia	4%
450	Sepsis	4%
451	Bacterial Vaginosis	3.9%
452	Human Ehrlichiosis	3.9%
453	Body Weight	3.9%
454	Abdomen, Acute	3.9%
455	Invasive Pulmonary Aspergillosis	3.8%
456	Respiratory Tract Fistula	3.8%
457	Toxoplasmosis, Cerebral	3.7%
458	Philadelphia Chromosome	3.7%
459	Apnea	3.7%
460	Cheyne-Stokes Respiration	3.7%
461	Decerebrate State	3.7%
462	Dyspnea	3.7%
463	Cardiomegaly	3.7%
464	Hemiparesis	3.7%
465	Hepatomegaly	3.7%
466	Hyperventilation	3.7%
467	Meningism	3.7%
468	Mouth Breathing	3.7%
469	Paresis	3.7%
470	Parovarian Cyst	3.7%
471	Pruritus	3.7%
472	Seizures	3.7%
473	Sensation Disorders	3.7%
474	Sneezing	3.7%
475	Spermatocele	3.7%
476	Erythema	3.7%
477	Oral Fistula	3.7%
478	Complex partial seizures	3.7%
479	Necrolytic Migratory Erythema	3.7%
480	Tachypnea	3.7%
481	Monoparesis	3.7%
482	Cutaneous Fistula	3.7%
483	Gait Disorders, Neurologic	3.7%
484	Neuromuscular Manifestations	3.7%
485	Cardiac Hypertrophy	3.7%
486	Edema, Cardiac	3.6%
487	Mental Fatigue	3.6%
488	Hirsutism	3.6%
489	Orthostatic intolerance	3.6%
490	Hypoventilation	3.6%
491	Vaginal Fistula	3.6%
492	Rectocele	3.6%
493	Body Weight Changes	3.6%
494	Japanese Spotted Fever	3.5%
495	Lung Diseases, Fungal	3.4%
496	Human anaplasmosis	3.4%
497	Pneumonia, Bacterial	3.3%
498	Hoarseness	3.3%
499	Autoimmune thrombocytopenia	3.3%
500	Immune thrombocytopenic purpura	3.3%
501	Actinomycetales Infections	3.3%
502	Bordetella Infections	3.3%
503	Brucellosis	3.3%
504	Campylobacter infection	3.3%
505	Clostridium Infections	3.3%
506	Enterobacteriaceae Infections	3.3%
507	Listeriosis	3.3%
508	Mucormycosis	3.3%
509	Pseudomonas Infections	3.3%
510	Q Fever	3.3%
511	Staphylococcal Infections	3.3%
512	Streptococcal Infections	3.3%
513	Vibrio Infections	3.3%
514	Helicobacter Infections	3.3%
515	Bacillaceae Infections	3.3%
516	Neisseriaceae Infections	3.3%
517	Burkholderia Infections	3.3%
518	Clostridium difficile infection	3.3%
519	Flavobacteriaceae Infections	3.3%
520	Moraxellaceae Infections	3.3%
521	Burkholderia cepacia Infection	3.3%
522	Meningitis, Cryptococcal	3.2%
523	Sarcopenia	3.2%
524	Sleep Wake Disorders	3.2%
525	Pupil Disorders	3.2%
526	Neurobehavioral Manifestations	3.2%
527	Nasal Polyps	3.1%
528	Rocky Mountain Spotted Fever	3%
529	Pleural Rub	3%
530	Rales	3%
531	Respiratory Sounds	3%
532	Rhonchi	3%
533	Stridor	3%
534	Wheezing	3%
535	Asterixis	3%
536	Ballismus	3%
537	Vertigo	3%
538	Pain	3%
539	Livedo Reticularis	3%
540	Ache	3%
541	Meningocele	3%
542	Oliguria	3%
543	Polyuria	3%
544	Proteinuria	3%
545	Urinary Calculi	3%
546	Encephalocele	3%
547	Underweight	3%
548	Overweight	3%
549	Back Pain	2.8%
550	Bulimia	2.8%
551	Neck Pain	2.8%
552	Chest Pain	2.8%
553	Colonic Polyps	2.8%
554	Dizziness	2.8%
555	Dysuria	2.8%
556	Facial Pain	2.8%
557	Fever of Unknown Origin	2.8%
558	Flank Pain	2.8%
559	Headache	2.8%
560	Nocturia	2.8%
561	Pain, Intractable	2.8%
562	Pelvic Pain	2.8%
563	Snoring	2.8%
564	Chronic pain	2.8%
565	Lightheadedness	2.8%
566	Pain, Referred	2.8%
567	Prostatism	2.8%
568	Throbbing Headache	2.8%
569	Labor Pain	2.8%
570	Cancer Pain	2.8%
571	Nociceptive Pain	2.8%
572	Liver Abscess, Amebic	2.8%
573	Gait Ataxia	2.8%
574	Meningitis, Listeria	2.8%
575	Erysipelothrix infection	2.7%
576	Syphilis, Congenital	2.7%
577	Basal Ganglia Hemorrhage	2.7%
578	Voice Disorders	2.7%
579	Voice Disturbance	2.7%
580	Oral candidiasis	2.7%
581	Pulmonary Aspergillosis	2.6%
582	Bronchopulmonary Aspergillosis	2.6%
583	Gagging	2.6%
584	Leukoplakia, Oral	2.6%
585	Meningitis, Haemophilus	2.5%
586	Meningitis, Pneumococcal	2.5%
587	Akathisia	2.4%
588	Restlessness	2.4%
589	Psychomotor Agitation	2.4%
590	Acinetobacter Infections	2.4%
591	Actinomycosis	2.4%
592	Bacteroides Infections	2.4%
593	Cholera	2.4%
594	Corynebacterium Infections	2.4%
595	Escherichia coli Infections	2.4%
596	Gas Gangrene	2.4%
597	Haemophilus Infections	2.4%
598	Klebsiella Infections	2.4%
599	Meningococcal Infections	2.4%
600	Mycobacterium Infections	2.4%
601	Mycoplasma Infections	2.4%
602	Nocardia Infections	2.4%
603	Pasteurella Infections	2.4%
604	Pneumococcal Infections	2.4%
605	Proteus Infections	2.4%
606	Rickettsia Infections	2.4%
607	Salmonella infections	2.4%
608	Scarlet Fever	2.4%
609	Scrub Typhus	2.4%
610	Tetanus	2.4%
611	Serratia Infections	2.4%
612	Ureaplasma Infections	2.4%
613	Pulmonary Nocardiosis	2.4%
614	Vesicovaginal Fistula	2.4%
615	Biliary Fistula	2.3%
616	Gastric Fistula	2.3%
617	Congenital diaphragmatic hernia	2.3%
618	Morning Sickness	2.3%
619	Anosmia	2.3%
620	Ataxia	2.3%
621	Athetosis	2.3%
622	Catalepsy	2.3%
623	Dental Fistula	2.3%
624	Dystonia	2.3%
625	Hemiplegia	2.3%
626	Locked-In Syndrome	2.3%
627	Muscle Hypertonia	2.3%
628	Muscle hypotonia	2.3%
629	Myoclonus	2.3%
630	Myotonia	2.3%
631	Neuralgia	2.3%
632	Oroantral Fistula	2.3%
633	Paraplegia	2.3%
634	Pseudobulbar Palsy	2.3%
635	Quadriplegia	2.3%
636	Spasm	2.3%
637	Spastic Paraplegia	2.3%
638	Status Epilepticus	2.3%
639	Taste Disorders	2.3%
640	Tremor	2.3%
641	Monoplegia	2.3%
642	Hypokinesia	2.3%
643	Left Ventricular Hypertrophy	2.3%
644	Gastroparesis	2.3%
645	Right Ventricular Hypertrophy	2.3%
646	Paraparesis	2.3%
647	Bradykinesia	2.3%
648	Waxy flexibility	2.3%
649	Action Tremor	2.3%
650	Resting Tremor	2.3%
651	Dysosmia	2.3%
652	Quadriparesis	2.3%
653	Olfaction Disorders	2.3%
654	Myokymia	2.3%
655	Somatosensory Disorders	2.3%
656	Neuropathic pain	2.3%
657	Hyperkinesia	2.3%
658	Intention tremor	2.3%
659	Jet Lag Syndrome	2.3%
660	Rectal Prolapse	2.3%
661	Uterine Prolapse	2.3%
662	Vaginal Prolapse	2.3%
663	Reflex, Abnormal	2.3%
664	Hyporeflexia	2.3%
665	Hyperreflexia	2.3%
666	Weight Gain	2.3%
667	Gait Apraxia	2.2%
668	Birth Weight	2.2%
669	Meningitis, Bacterial	2.2%
670	Meningitis, Fungal	2.2%
671	Candidiasis, Vulvovaginal	2.2%
672	Putaminal Hemorrhage	2.1%
673	Tuberculosis, Meningeal	2.1%
674	Diphtheria	2%
675	Emaciation	2%
676	Leprosy	2%
677	Low Back Pain	2%
678	Mycobacterium Infections, Nontuberculous	2%
679	Psittacosis	2%
680	Paratyphoid Fever	2%
681	Plague	2%
682	Tuberculosis	2%
683	Typhoid Fever	2%
684	TYPHUS	2%
685	Yersinia pseudotuberculosis Infections	2%
686	Visceral Pain	2%
687	Bubonic Plague	2%
688	Mycobacterium abscessus Infection	2%
689	Vision Disorders	2%
690	Metamorphopsia	2%
691	Visual Impairment	2%
692	Bronchial Fistula	1.9%
693	Metatarsalgia	1.9%
694	Pancreatic Fistula	1.9%
695	Anisocoria	1.9%
696	Confusion	1.9%
697	Facial paralysis	1.9%
698	Intestinal Fistula	1.9%
699	Lethargy	1.9%
700	Memory Disorders	1.9%
701	Muscle Cramp	1.9%
702	Perceptual Disorders	1.9%
703	Psychomotor Disorders	1.9%
704	Tonic Pupil	1.9%
705	Anhedonia	1.9%
706	Disorientation	1.9%
707	Gastroschisis	1.9%
708	Enterocutaneous Fistula	1.9%
709	Fetal Hypoxia	1.9%
710	Facial Paresis	1.9%
711	Memory Loss	1.9%
712	Hemisensory Neglect	1.9%
713	Dysacusis	1.9%
714	Dyspnea, Paroxysmal	1.9%
715	Mastodynia	1.9%
716	Respiratory Paralysis	1.9%
717	Salivary Gland Fistula	1.9%
718	Chorea	1.9%
719	Cystocele	1.9%
720	Tetany	1.9%
721	Urinary Incontinence	1.9%
722	Breakthrough Pain	1.9%
723	Albuminuria	1.9%
724	Hemoglobinuria	1.9%
725	Mycobacterium avium-intracellulare Infection	1.8%
726	Lymph Node Tuberculosis	1.8%
727	Tuberculosis, Miliary	1.8%
728	Tuberculosis, Multidrug-Resistant	1.8%
729	Leprosy, Multibacillary	1.8%
730	Latent Tuberculosis	1.8%
731	Hydrops Fetalis	1.8%
732	Alice in Wonderland Syndrome	1.8%
733	Fetal Weight	1.8%
734	Borderline leprosy	1.7%
735	Leprosy, Lepromatous	1.7%
736	Tuberculoid leprosy	1.7%
737	Extensively Drug-Resistant Tuberculosis	1.7%
738	Salmonella Infections, Animal	1.7%
739	Consciousness Disorders	1.7%
740	Mental Retardation	1.7%
741	Depressed Level of Consciousness	1.7%
742	Mental deficiency	1.7%
743	Intellectual Disability	1.7%
744	Catatonia	1.7%
745	Musculoskeletal Pain	1.7%
746	Ophthalmoplegia	1.7%
747	External Ophthalmoplegia	1.7%
748	Rheumatic Fever	1.7%
749	Umbilical hernia	1.6%
750	Rheumatic Heart Disease	1.6%
751	Toothache	1.6%
752	Aphonia	1.6%
753	Arthralgia	1.6%
754	Sleep Deprivation	1.6%
755	Polyarthralgia	1.6%
756	Dysphonia	1.6%
757	Cerebrospinal Fluid Otorrhea	1.6%
758	Cerebrospinal Fluid Rhinorrhea	1.6%
759	Hyperemesis Gravidarum	1.6%
760	Salmonella food poisoning	1.6%
761	Enterocolitis, Pseudomembranous	1.6%
762	pseudomembranous colitis	1.6%
763	Dysentery, Bacillary	1.6%
764	Dysgeusia	1.6%
765	Formication	1.6%
766	Hyperalgesia	1.6%
767	Hyperesthesia	1.6%
768	Hypesthesia	1.6%
769	Language Disorders	1.6%
770	Numbness	1.6%
771	Paresthesia	1.6%
772	Paraparesis, Spastic	1.6%
773	Trismus	1.6%
774	Epilepsia Partialis Continua	1.6%
775	Hypogeusia	1.6%
776	Brown-Sequard Syndrome	1.6%
777	Lockjaw	1.6%
778	Allodynia	1.6%
779	Ageusia	1.6%
780	Obesity	1.6%
781	Cachexia	1.6%
782	Alexia	1.6%
783	Dyslexia	1.6%
784	Tuberculosis, Gastrointestinal	1.5%
785	Vocal Cord Paralysis	1.5%
786	Tuberculosis, Central Nervous System	1.4%
787	Urinary Bladder Fistula	1.4%
788	Botulism	1.4%
789	Diplopia	1.4%
790	Muscle Rigidity	1.4%
791	Muscle Spasticity	1.4%
792	Scotoma	1.4%
793	Photophobia	1.4%
794	Cogwheel Rigidity	1.4%
795	Hemifacial Spasm	1.4%
796	Amaurosis	1.4%
797	Blindness	1.4%
798	Nuchal Rigidity	1.4%
799	Angina Pectoris	1.4%
800	Agnosia	1.4%
801	Apraxias	1.4%
802	Hallucinations	1.4%
803	Hemianopsia	1.4%
804	Hyperacusis	1.4%
805	Tinnitus	1.4%
806	Visual Agnosia	1.4%
807	Anosognosia	1.4%
808	Wernicke-Korsakoff Syndrome	1.4%
809	Phonophobia	1.4%
810	Hearing Loss	1.4%
811	Cerebellar Ataxia	1.3%
812	Torticollis	1.3%
813	Sciatica	1.3%
814	Urge Incontinence	1.3%
815	Tardive Dyskinesia	1.3%
816	Dyskinesia, Drug-Induced	1.3%
817	Agraphia	1.3%
818	Anomia	1.3%
819	Cluttering	1.3%
820	Language Development Disorders	1.3%
821	Speech Disorders	1.3%
822	Syncope	1.3%
823	Stupor	1.3%
824	Dysgraphia	1.3%
825	Presyncope	1.3%
826	Dyslalia	1.3%
827	Alcohol Withdrawal Seizures	1.3%
828	Arteriovenous fistula	1.3%
829	Tuberculosis, Pulmonary	1.2%
830	Aspergillosis, Allergic Bronchopulmonary	1.2%
831	Amblyopia	1.2%
832	Amnesia	1.2%
833	Delirium	1.2%
834	Horner Syndrome	1.2%
835	Dissociative Amnesia	1.2%
836	Color blindness	1.2%
837	Global Amnesia	1.2%
838	Rectal Fistula	1.2%
839	Anal Fistula	1.2%
840	Shoulder Pain	1.2%
841	Pediatric Obesity	1.1%
842	Kidney Calculi	1.1%
843	Ureteral Calculi	1.1%
844	Aphasia	1.1%
845	Articulation Disorders	1.1%
846	Echolalia	1.1%
847	Stuttering	1.1%
848	Dysphasia	1.1%
849	Amaurosis Fugax	1.1%
850	Blindness, Cortical	1.1%
851	Dyscalculia	1.1%
852	Angina, Unstable	1.1%
853	Deafness	1.1%
854	Hearing Loss, Sudden	1.1%
855	Gerstmann Syndrome	1.1%
856	Hearing Loss, Bilateral	1.1%
857	Hearing Loss, High-Frequency	1.1%
858	Hearing Loss, Mixed Conductive-Sensorineural	1.1%
859	Prosopagnosia	1.1%
860	Apraxia, Ideomotor	1.1%
861	Persistent Vegetative State	1.1%
862	Charles Bonnet Syndrome	1.1%
863	Hearing Loss, Unilateral	1.1%
864	Complete Hearing Loss	1.1%
865	Alien Hand Syndrome	1.1%
866	Deaf Mutism	1.1%
867	Akathisia, Drug-Induced	1%
868	Dysarthria	1%
869	Myalgia	1%
870	Mutism	1%
871	Selective Mutism	1%
872	Angina Pectoris, Variant	0.9%
873	Retrograde amnesia	0.9%
874	Amnesia, Anterograde	0.9%
875	Lemierre Syndrome	0.9%
876	Auditory Perceptual Disorders	0.9%
877	Tuberculosis, Renal	0.9%
878	Alexia, Pure	0.9%
879	Ophthalmoplegic Migraine	0.8%
880	Progressive supranuclear palsy	0.8%
881	Amnesia, Transient Global	0.8%
882	Kearns-Sayre syndrome	0.5%

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