MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Scrub Typhus

(UMLS:C0036472)

Definition:: An acute infectious disease caused by ORIENTIA TSUTSUGAMUSHI. It is limited to eastern and southeastern Asia, India, northern Australia, and the adjacent islands. Characteristics include the formation of a primary cutaneous lesion at the site of the bite of an infected mite, fever lasting about two weeks, and a maculopapular rash.
UMLS ID:: C0036472
MeSH ID:: D012612

Classification:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.400.780.850

Synonym(s)

Scrub Typhus

FEVER, JAPANESE RIVER

Japanese river fever

Japanese river; fever

Japanese; typhus

Kedani fever

Mite-borne typhus

Mite-borne typhus due to Rickettsia tsutsugamushi

Rickettsia; tsutsugamushi, typhus

10.

Scrub mite-borne typhus

11.

Scrub typhus

12.

Sumatran mite; fever

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Doxycycline	FAERS: 1		US FAERS
2	Imatinib Mesylate	FAERS: 1		US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Rickettsia Infections	48.4%
2	Japanese Spotted Fever	39%
3	TYPHUS	36%
4	Bordetella Infections	34.4%
5	Brucellosis	34.4%
6	Campylobacter infection	34.4%
7	Enterobacteriaceae Infections	34.4%
8	Pseudomonas Infections	34.4%
9	Q Fever	34.4%
10	Vibrio Infections	34.4%
11	Helicobacter Infections	34.4%
12	Neisseriaceae Infections	34.4%
13	Burkholderia Infections	34.4%
14	Flavobacteriaceae Infections	34.4%
15	Moraxellaceae Infections	34.4%
16	Burkholderia cepacia Infection	34.4%
17	Borrelia Infections	33%
18	Leptospirosis	33%
19	Rocky Mountain Spotted Fever	31%
20	Human Ehrlichiosis	30.1%
21	Lyme Disease	27.4%
22	Relapsing Fever	27.4%
23	Gram-Positive Bacterial Infections	25.4%
24	Human anaplasmosis	23.9%
25	Acinetobacter Infections	22.6%
26	Bacteroides Infections	22.6%
27	Cholera	22.6%
28	Escherichia coli Infections	22.6%
29	Haemophilus Infections	22.6%
30	Klebsiella Infections	22.6%
31	Meningococcal Infections	22.6%
32	Mycoplasma Infections	22.6%
33	Pasteurella Infections	22.6%
34	Proteus Infections	22.6%
35	Salmonella infections	22.6%
36	Serratia Infections	22.6%
37	Ureaplasma Infections	22.6%
38	Lyme Neuroborreliosis	18.5%
39	Central Nervous System Bacterial Infections	17.1%
40	Psittacosis	16.8%
41	Paratyphoid Fever	16.8%
42	Plague	16.8%
43	Typhoid Fever	16.8%
44	Yersinia pseudotuberculosis Infections	16.8%
45	Bubonic Plague	16.8%
46	Bacterial Vaginosis	16.6%
47	Mycoses	16.4%
48	Infection	16.4%
49	Neurosyphilis	15.5%
50	Skin Diseases, Bacterial	15.1%
51	Bacteremia	14.9%
52	Actinomycetales Infections	14.8%
53	Clostridium Infections	14.8%
54	Listeriosis	14.8%
55	Staphylococcal Infections	14.8%
56	Streptococcal Infections	14.8%
57	Bacillaceae Infections	14.8%
58	Clostridium difficile infection	14.8%
59	Erythema Chronicum Migrans	14.7%
60	Syphilis	14.3%
61	Pertussis	14.2%
62	Chlamydia Infections	13.5%
63	Gonorrhea	13.5%
64	Ulcerative stomatitis	12.7%
65	Pneumonia, Bacterial	12.6%
66	Syphilis, Congenital	12.3%
67	Bacterial Endocarditis	12.2%
68	Salmonella Infections, Animal	12.1%
69	Salmonella food poisoning	11.4%
70	Dysentery, Bacillary	11.3%
71	Erysipelas	11%
72	Staphylococcal Skin Infections	11%
73	Central Nervous System Infection	10.8%
74	Erysipelothrix infection	10.6%
75	Meningitis, Haemophilus	10.6%
76	Erythrasma	10%
77	Actinomycosis	9.7%
78	Corynebacterium Infections	9.7%
79	Gas Gangrene	9.7%
80	Mycobacterium Infections	9.7%
81	Nocardia Infections	9.7%
82	Pneumococcal Infections	9.7%
83	Scarlet Fever	9.7%
84	Tetanus	9.7%
85	Pulmonary Nocardiosis	9.7%
86	Impetigo	9.6%
87	Lymphogranuloma Venereum	9.6%
88	Ecthyma	9.2%
89	Subacute Bacterial Endocarditis	9.2%
90	Rhinoscleroma	9%
91	Aspergillosis	8.5%
92	Candidiasis	8.5%
93	Coccidioidomycosis	8.5%
94	Histoplasmosis	8.5%
95	Paracoccidioidomycosis	8.5%
96	Pelvic Infection	8.5%
97	Wound Infection	8.5%
98	Zygomycosis	8.5%
99	Soft Tissue Infection	8.5%
100	Community-Acquired Infections	8.5%
101	Phaeohyphomycosis	8.5%
102	Pneumocystis Infections	8.5%
103	Ophthalmia Neonatorum	8.4%
104	Trachoma	8.4%
105	Mycetoma	8.3%
106	Meningitis, Listeria	7.7%
107	Staphylococcal Scalded Skin Syndrome	7.7%
108	Hidradenitis Suppurativa	7.6%
109	Meningitis, Bacterial	7.4%
110	Hordeolum	7.3%
111	Bacterial conjunctivitis	7.2%
112	Diphtheria	7.2%
113	Leprosy	7.2%
114	Mycobacterium Infections, Nontuberculous	7.2%
115	Tuberculosis	7.2%
116	Mycobacterium abscessus Infection	7.2%
117	Meningitis, Pneumococcal	6.7%
118	Dermatomycoses	6.7%
119	Furunculosis	6.5%
120	furuncle	6.5%
121	Eye Infection	6%
122	Respiratory Tract Infections	6%
123	carbuncle	6%
124	Mycobacterium avium-intracellulare Infection	6%
125	Lymph Node Tuberculosis	6%
126	Tuberculosis, Miliary	6%
127	Tuberculosis, Multidrug-Resistant	6%
128	Leprosy, Multibacillary	6%
129	Latent Tuberculosis	6%
130	Bone Diseases, Infectious	5.7%
131	Otomycosis	5.7%
132	Pregnancy Complications, Infectious	5.7%
133	Skin Diseases, Infectious	5.7%
134	Arthritis, Infectious	5.6%
135	Piedra	5.6%
136	Central Nervous System Fungal Infections	5.6%
137	Suppuration	5.6%
138	Cross Infection	5.6%
139	Septicemia	5.6%
140	Sepsis	5.6%
141	Joint Tuberculosis	5.5%
142	Tuberculosis, Osteoarticular	5.5%
143	Bone Tuberculosis	5.5%
144	Borderline leprosy	5.4%
145	Leprosy, Lepromatous	5.4%
146	Tuberculoid leprosy	5.4%
147	Extensively Drug-Resistant Tuberculosis	5.4%
148	Candidiasis, Chronic Mucocutaneous	5.2%
149	Cutaneous Candidiasis	5.2%
150	Rheumatic Fever	5%
151	Tuberculosis, Meningeal	5%
152	Rheumatic Heart Disease	5%
153	Lemierre Syndrome	4.9%
154	Mucormycosis	4.9%
155	Neuroaspergillosis	4.9%
156	Fungemia	4.9%
157	Enterocolitis, Pseudomembranous	4.8%
158	pseudomembranous colitis	4.8%
159	Opportunistic Infections	4.7%
160	Brain Abscess	4.7%
161	Panophthalmitis	4.4%
162	Erythema Induratum	4.4%
163	Lung Diseases, Fungal	4.3%
164	Candidemia	4.3%
165	Urinary tract infection	4.3%
166	Waterhouse-Friderichsen Syndrome	4.3%
167	Tuberculosis, Gastrointestinal	4.1%
168	Chromoblastomycosis	4.1%
169	Dermatophytosis	4.1%
170	Sporotrichosis	4.1%
171	Tinea	4.1%
172	Tinea Versicolor	4.1%
173	Trichophytosis	4.1%
174	Invasive Pulmonary Aspergillosis	4.1%
175	Hyalohyphomycosis	4.1%
176	Endotoxemia	4%
177	Botulism	4%
178	Cellulitis	4%
179	Tuberculosis, Central Nervous System	4%
180	Blastomycosis	3.8%
181	Sexually Transmitted Diseases	3.5%
182	Tuberculosis, Spinal	3.4%
183	Oral candidiasis	3.4%
184	Endophthalmitis	3.4%
185	Peritonitis	3.4%
186	Osteomyelitis	3.3%
187	Periostitis	3.3%
188	Surgical Wound Infection	3.3%
189	Pulmonary Aspergillosis	3.3%
190	Bronchopulmonary Aspergillosis	3.3%
191	Abscess	3.3%
192	Adnexitis	3.3%
193	Empyema	3.3%
194	Pelvic Inflammatory Disease	3.3%
195	Meningitis, Cryptococcal	3.2%
196	Psoas Abscess	3.2%
197	Abdominal Abscess	3.2%
198	Tuberculosis, Pulmonary	3.2%
199	Fusariosis	2.8%
200	Superinfection	2.6%
201	Corneal Ulcer	2.5%
202	Puerperal Infection	2.5%
203	Spondylitis	2.5%
204	Appendicitis	2.5%
205	Bacteriuria	2.5%
206	Pyuria	2.5%
207	Meningitis, Fungal	2.5%
208	Pyomyositis	2.5%
209	Endotoxic shock	2.4%
210	Septic Shock	2.4%
211	Toxic Shock Syndrome	2.4%
212	Candidiasis, Vulvovaginal	2.4%
213	Tinea Capitis	2.3%
214	Onychomycosis	2.3%
215	Diverticulitis	2.2%
216	Arthritis, Reactive	1.9%
217	Tinea Pedis	1.9%
218	Tuberculosis, Renal	1.9%
219	Toxoplasmosis, Cerebral	1.8%
220	Lung Abscess	1.7%
221	AIDS-Related Opportunistic Infections	1.7%
222	Liver Abscess	1.7%
223	Diverticulum	1.7%
224	Diverticulosis	1.7%
225	Discitis	1.6%
226	Mastoiditis	1.6%
227	Petrositis	1.6%
228	Retropharyngeal Abscess	1.3%
229	Epidural Abscess	1.3%
230	Peritonsillar Abscess	1.3%
231	Aspergillosis, Allergic Bronchopulmonary	1.1%
232	Liver Abscess, Amebic	0.7%

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