MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Heroin Dependence

(UMLS:C0019337)

Definition:: Strong dependence or addiction, both physiological and emotional, upon HEROIN.
UMLS ID:: C0019337
MeSH ID:: D006556

Classification 1:

Name:

Chemically-Induced Disorders
MeSH Tree Number(s):: C25.775.675.400

Classification 2:

Name:

Mental Disorders
MeSH Tree Number(s):: F03.900.675.300

Synonym(s)

Heroin Dependence

Addiction;drug(s);heroin

Heroin Addiction

Heroin addiction

Heroin dependence

addiction drug heroin

addiction heroin

addictions heroin

dependence; heroin

10.

heroin addiction

11.

heroin dependence

12.

heroin; dependence

13.

opioid dependence heroin

Associated Drug(s)

	Name	Reference(s)	Data Source
1	6-O-monoacetylmorphine	9835076 11599593	CTD
2	Amphetamine	9824469	CTD
3	Baclofen	11862373	CTD
4	Buprenorphine, Naloxone Drug Combination	19948382	CTD
5	Buprenorphine	View details 10529020 10630350 11164693 11377924 11481150 12392802 12756210 15349002 16493349 16814005 18294936 18621943 19224082 19269730 21866885	CTD
6	Cannabinoids	11590424	CTD
7	Clonidine	4028630 6120359	CTD
8	Cocaine	9824469	CTD
9	Fluoxetine	19150250	CTD
10	Flupenthixol	10481841	CTD
11	Heroin	View details 225122 4433085 6676478 9643465 9824469 10529020 11173169 11519628 11862373 15717844 15986265 16002042 16085366 16598705 16759341 18365934 19067385 19948382	CTD
12	Hydrocortisone	18201294	CTD
13	Lu 19005	11377924	CTD
14	Magnesium	18705537	CTD
15	Methadone	View details 56139 4028630 6108101 7869468 10768702 11173169 12859171 15477802 15608471 15717844 15964714 15986265 16085366 16162728 16238992 16389204 16496034 16759341 16814005 16865634 17026725 17222284 17278675 17378505 17628351 17784892 19150250 19339140 19540702 19930027 20180662 20532873 20827272	CTD
16	Morphine	16598705	CTD
17	Naloxone	225122	CTD
18	Naltrexone	View details 56139 999987 6120359 10529020 12144610 16496034	CTD
19	Quinpirole	11751029	CTD
20	Sulpiride	622221	CTD
21	Vigabatrin	14515344	CTD
22	carbidopa, levodopa drug combination	11750899	CTD
23	lofexidine	11522461	CTD
24	quadazocine	10481841	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Morphine Dependence	46.7%
2	Marijuana Abuse	31%
3	Nicotine Dependence	31%
4	Phencyclidine Abuse	31%
5	Substance Abuse, Intravenous	31%
6	Substance Withdrawal Syndrome	31%
7	Tobacco Use Disorder	31%
8	Alcohol-Related Disorders	31%
9	Amphetamine-Related Disorders	31%
10	Cocaine-Related Disorders	31%
11	Psychoses, Substance-Induced	26.4%
12	Neonatal Abstinence Syndrome	25%
13	Alcohol Use Disorder	20%
14	Alcoholic Intoxication	20%
15	Alcohol abuse	20%
16	Alcohol Withdrawal Delirium	19.2%
17	Binge Drinking	15.9%
18	Psychoses, Alcoholic	15.4%
19	Drug Overdose	15.1%
20	Neurotic Disorders	14.3%
21	Alcohol-Induced Disorders	13.3%
22	Anxiety Disorders	11.9%
23	Avoidant Personality Disorder	11.9%
24	Dissociative disorder	11.9%
25	Drug toxicity	11.9%
26	Frigidity	11.9%
27	Hypoactive Sexual Desire Disorder	11.9%
28	Disruptive, Impulse Control, and Conduct Disorders	11.9%
29	Intermittent Explosive Disorder	11.9%
30	Kleptomania	11.9%
31	Narcissistic Personality Disorder	11.9%
32	Personality Disorders	11.9%
33	Poisoning	11.9%
34	Sexual Aversion Disorder	11.9%
35	Somatoform Disorder	11.9%
36	Dissociation	11.9%
37	Motor Disorders	11.9%
38	Mood Disorders	11.9%
39	Schizophrenia Spectrum and Other Psychotic Disorders	11.9%
40	Neurodevelopmental Disorders	11.9%
41	Neurocognitive Disorders	11.9%
42	Feeding and Eating Disorders	11.9%
43	Wernicke Encephalopathy	11.3%
44	Separation Anxiety Disorder	10.3%
45	Alcohol Withdrawal Seizures	9.2%
46	Alcohol-Induced Disorders, Nervous System	8.7%
47	Chemical and Drug Induced Liver Injury	8.3%
48	Cardiomyopathy, Alcoholic	7.4%
49	Pancreatitis, Alcoholic	7.4%
50	Sleep Wake Disorders	7.2%
51	Adjustment Disorders	6.8%
52	Affective Disorders, Psychotic	6.8%
53	Agoraphobia	6.8%
54	Anorexia Nervosa	6.8%
55	Antisocial Personality Disorder	6.8%
56	Bipolar Disorder	6.8%
57	Body Dysmorphic Disorders	6.8%
58	Borderline Personality Disorder	6.8%
59	Capgras Syndrome	6.8%
60	Child Behavior Disorders	6.8%
61	Developmental Disabilities	6.8%
62	Child Development Disorders, Pervasive	6.8%
63	Claustrophobia	6.8%
64	Cognition Disorders	6.8%
65	Conversion disorder	6.8%
66	Cyclothymic Disorder	6.8%
67	Dependent Personality Disorder	6.8%
68	Depressive disorder	6.8%
69	Developmental Coordination Disorder	6.8%
70	Exhibitionism	6.8%
71	Factitious Disorders	6.8%
72	Firesetting Behavior	6.8%
73	Fluoride Poisoning	6.8%
74	Food Poisoning	6.8%
75	Gas Poisoning	6.8%
76	Head Banging	6.8%
77	Histrionic Personality Disorder	6.8%
78	Hypochondriasis	6.8%
79	Masochism	6.8%
80	Melancholia	6.8%
81	Motor Skills Disorders	6.8%
82	Dissociative Identity Disorder	6.8%
83	Mycotoxicosis	6.8%
84	Neurasthenia	6.8%
85	Obsessive-Compulsive Disorder	6.8%
86	Oppositional Defiant Disorder	6.8%
87	Panic Disorder	6.8%
88	Paranoid Personality Disorder	6.8%
89	Pedophilia	6.8%
90	Plant Poisoning	6.8%
91	Pseudodementia	6.8%
92	Psychotic Disorders	6.8%
93	Sadism	6.8%
94	Schizoaffective Disorder	6.8%
95	Schizoid Personality Disorder	6.8%
96	Schizophrenia	6.8%
97	Schizophrenia, Childhood	6.8%
98	Schizotypal Personality Disorder	6.8%
99	Stereotypic Movement Disorder	6.8%
100	Transvestism	6.8%
101	Trichotillomania	6.8%
102	Voyeurism	6.8%
103	Anticholinergic Syndrome	6.8%
104	Attention Deficit and Disruptive Behavior Disorders	6.8%
105	Hyperkinetic Heart Syndrome	6.8%
106	Reactive Attachment Disorder	6.8%
107	Sexual and Gender Disorders	6.8%
108	Gender Dysphoria	6.8%
109	Serotonin Syndrome	6.8%
110	Organophosphate poisoning	6.8%
111	Propofol Infusion Syndrome	6.8%
112	Paranoia	6.8%
113	Compulsive Personality Disorder	6.8%
114	Bulimia Nervosa	6.8%
115	Mushroom Poisoning	6.7%
116	Fetal Alcohol Spectrum Disorders	6%
117	Bites and Stings	5.4%
118	Neurotoxicity Syndromes	5.4%
119	Chemical and Drug Induced Liver Injury, Chronic	5.3%
120	Parasomnia	5.2%
121	Dyssomnias	5.2%
122	Metabolic Side Effects of Drugs and Substances	5.2%
123	Gambling	5.1%
124	Premature Ejaculation	5.1%
125	Water Intoxication	5.1%
126	Injection Site Reaction	5.1%
127	Erectile dysfunction	5.1%
128	Arsenic Poisoning	5.1%
129	Dementia	5.1%
130	Infusion site reaction	5.1%
131	Fatty Liver, Alcoholic	5%
132	Hepatitis, Alcoholic	5%
133	Liver Cirrhosis, Alcoholic	5%
134	Akathisia, Drug-Induced	4.8%
135	Cadmium poisoning	4.4%
136	Carbon Monoxide Poisoning	4.4%
137	Ciguatera Poisoning	4.4%
138	Combat Disorders	4.4%
139	Dysthymic Disorder	4.4%
140	Ergotism	4.4%
141	Hysteria	4.4%
142	Lead Poisoning	4.4%
143	Mercury Poisoning	4.4%
144	Schizophrenia, Catatonic	4.4%
145	Schizophrenia, Disorganized	4.4%
146	Post-Traumatic Stress Disorder	4.4%
147	Attention Deficit Disorder	4.4%
148	Seasonal Affective Disorder	4.4%
149	Conduct Disorder	4.4%
150	Social Communication Disorder	4.4%
151	Shellfish Poisoning	4.4%
152	Psychological Trauma	4.4%
153	Hoarding Disorder	4.4%
154	Phonological Disorder	4.4%
155	Dyskinesia, Drug-Induced	4.2%
156	Dyspareunia	4%
157	Mutism	4%
158	Selective Mutism	4%
159	Cardiotoxicity	3.4%
160	Restless Legs Syndrome	3.4%
161	Consciousness Disorders	3.4%
162	Insect Bites and Stings	3.4%
163	Mental Retardation	3.4%
164	Depressed Level of Consciousness	3.4%
165	Mental deficiency	3.4%
166	Intellectual Disability	3.4%
167	Enuresis	3.4%
168	Argyria	3.3%
169	Depression, Postpartum	3.3%
170	Sleep Talking	3.3%
171	Manganese Poisoning	3.3%
172	Sleep Disorders, Intrinsic	3.3%
173	Amnesia	3.3%
174	Delirium	3.3%
175	Dissociative Amnesia	3.3%
176	Global Amnesia	3.3%
177	Kluver-Bucy Syndrome	3.3%
178	Premenstrual Dysphoric Disorder	3.3%
179	Autistic Disorder	3.3%
180	Asperger Syndrome	3.3%
181	Salmonella food poisoning	3.3%
182	Huntington Disease	2.9%
183	Tick Paralysis	2.7%
184	Neuroleptic Malignant Syndrome	2.7%
185	Drug Eruptions	2.7%
186	Sleep Bruxism	2.7%
187	Presenile dementia	2.6%
188	Senile dementia	2.6%
189	Creutzfeldt-Jakob disease	2.6%
190	Dyscalculia	2.6%
191	Alexia, Pure	2.6%
192	Mercury Poisoning, Nervous System	2.5%
193	Lead Poisoning, Nervous System	2.5%
194	Disorders of Excessive Somnolence	2.5%
195	Sleep Initiation and Maintenance Disorders	2.5%
196	Night Terrors	2.5%
197	Somnambulism	2.5%
198	Transient Insomnia	2.5%
199	Sleep Paralysis	2.5%
200	Chronic Insomnia	2.5%
201	REM Sleep Behavior Disorder	2.5%
202	Hypersomnia	2.5%
203	Sleep Disorders, Circadian Rhythm	2.3%
204	Botulism	2.2%
205	Sleep Deprivation	2.2%
206	MPTP Poisoning	2.2%
207	Diurnal Enuresis	2.2%
208	Retrograde amnesia	2.2%
209	Amnesia, Anterograde	2.2%
210	Lead Poisoning, Nervous System, Childhood	2%
211	Lead Poisoning, Nervous System, Adult	2%
212	Narcolepsy	2%
213	Kleine-Levin Syndrome	2%
214	Pick Disease of the Brain	2%
215	Acute Generalized Exanthematous Pustulosis	2%
216	Asthma, Aspirin-Induced	1.9%
217	Lewy Body Disease	1.9%
218	AIDS Dementia Complex	1.9%
219	Amnesia, Transient Global	1.9%
220	Alexia	1.8%
221	Dyslexia	1.8%
222	Cataplexy	1.8%
223	Acrodynia	1.6%
224	Erythema Nodosum	1.6%
225	Serum Sickness	1.6%
226	Auditory Perceptual Disorders	1.6%
227	Frontotemporal dementia	1.6%
228	Dementia, Vascular	1.4%
229	Jet Lag Syndrome	1.4%
230	Toxic Epidermal Necrolysis	1.2%
231	Stevens-Johnson Syndrome	1.2%

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