MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Actinomycosis

(UMLS:C0001261)

Definition:: Infections with bacteria of the genus ACTINOMYCES.
UMLS ID:: C0001261
MeSH ID:: D000196

Classification:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.410.040.137

Synonym(s)

Actinomycosis

ACTINOMYCOSIS

Actinomyces; infection

Actinomycosis, NOS

Actinomycosis, unspecified

Actinomycotic infection

Actinomycotic infection of unspecified site

Actinomycotic infection, NOS

actinomyces infection

10.

actinomycoses

11.

actinomycosis

12.

actinomycotic infection

13.

actinomycotic; infection

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Zoledronic Acid	FAERS: 91		OFFSIDES US FAERS
2	Alendronate	FAERS: 53		OFFSIDES US FAERS
3	Norgestrel	FAERS: 53 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
4	Pamidronate	FAERS: 15		US FAERS
5	Copper	FAERS: 14		US FAERS
6	Methotrexate	FAERS: 7		US FAERS
7	Ibandronic Acid	FAERS: 3		US FAERS
8	Sunitinib	FAERS: 3		US FAERS
9	gemcitabine	FAERS: 3		US FAERS
10	Cyclosporine	FAERS: 2		US FAERS
11	Daptomycin	FAERS: 2		US FAERS
12	Decitabine	FAERS: 2		US FAERS
13	Everolimus	FAERS: 2		US FAERS
14	Imatinib Mesylate	FAERS: 2		US FAERS
15	Lapatinib	FAERS: 2		US FAERS
16	Risedronic Acid	FAERS: 2		OFFSIDES US FAERS
17	Alendronate	FAERS: 1		US FAERS
18	Budesonide	FAERS: 1		US FAERS
19	Fluticasone	FAERS: 1		OFFSIDES US FAERS
20	Lenalidomide	FAERS: 1		US FAERS
21	Mesalamine	FAERS: 1		US FAERS
22	Methadone	FAERS: 1		US FAERS
23	Prednisone	FAERS: 1		US FAERS
24	Sirolimus	FAERS: 1		US FAERS
25	Sitagliptin Phosphate	FAERS: 1		US FAERS
26	dabrafenib	FAERS: 1		US FAERS
27	pasireotide	FAERS: 1		US FAERS
28	Acyclovir			OFFSIDES
29	Alprazolam			OFFSIDES
30	Aminocaproic Acid			OFFSIDES
31	Amisulpride			OFFSIDES
32	Amitriptyline			OFFSIDES
33	Amoxicillin			OFFSIDES
34	Ampicillin			OFFSIDES
35	Anastrozole			OFFSIDES
36	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination			OFFSIDES
37	Atorvastatin			OFFSIDES
38	Atropine			OFFSIDES
39	Beclomethasone			OFFSIDES
40	Benztropine			OFFSIDES
41	Betamethasone Valerate			OFFSIDES
42	Bethanechol			OFFSIDES
43	Bimatoprost			OFFSIDES
44	Bisacodyl			OFFSIDES
45	Bumetanide			OFFSIDES
46	Bupivacaine			OFFSIDES
47	Bupropion			OFFSIDES
48	Calcium Chloride			OFFSIDES
49	Calcium Compounds			OFFSIDES
50	Carbamazepine			OFFSIDES
51	Cefadroxil			OFFSIDES
52	Ceftriaxone			OFFSIDES
53	Cefuroxime			OFFSIDES
54	Celecoxib			OFFSIDES
55	Cephalexin			OFFSIDES
56	Chlorhexidine			OFFSIDES
57	Chlorpromazine			OFFSIDES
58	Chlorthalidone			OFFSIDES
59	Cisapride			OFFSIDES
60	Clindamycin			OFFSIDES
61	Clodronic Acid			OFFSIDES
62	Clonidine			OFFSIDES
63	Clopidogrel			OFFSIDES
64	Clotrimazole			OFFSIDES
65	Cortisone			OFFSIDES
66	Cortisone			OFFSIDES
67	Cyproheptadine			OFFSIDES
68	Cyproterone Acetate			OFFSIDES
69	Dapsone			OFFSIDES
70	Dexamethasone			OFFSIDES
71	Diclofenac			OFFSIDES
72	Dicloxacillin			OFFSIDES
73	Dioctyl Sulfosuccinic Acid			OFFSIDES
74	Diphenoxylate			OFFSIDES
75	Docetaxel			OFFSIDES
76	Docusate sodium			OFFSIDES
77	Domperidone			OFFSIDES
78	Doxazosin			OFFSIDES
79	Doxorubicin			OFFSIDES
80	Doxycycline			OFFSIDES
81	Econazole			OFFSIDES
82	Epinephrine			OFFSIDES
83	Eptifibatide			OFFSIDES
84	Ertapenem			OFFSIDES
85	Estradiol			OFFSIDES
86	Estrogens, Conjugated (USP)			OFFSIDES
87	Etodolac			OFFSIDES
88	Famotidine			OFFSIDES
89	Fenofibrate			OFFSIDES
90	Fludrocortisone			OFFSIDES
91	Fluorouracil			OFFSIDES
92	Flurazepam			OFFSIDES
93	Fosinopril			OFFSIDES
94	Fulvestrant			OFFSIDES
95	Furosemide			OFFSIDES
96	Gabapentin			OFFSIDES
97	Glucovance			OFFSIDES
98	Glyburide			OFFSIDES
99	Goserelin			OFFSIDES
100	Granisetron			OFFSIDES
101	Hydrocodone			OFFSIDES
102	Hydrocortisone sodium succinate			OFFSIDES
103	Hydromorphone			OFFSIDES
104	Hydroxyzine			OFFSIDES
105	Imipenem		15155214	CTD
106	Ipratropium			OFFSIDES
107	Isradipine			OFFSIDES
108	Itraconazole			OFFSIDES
109	Ketoconazole			OFFSIDES
110	Ketorolac			OFFSIDES
111	Ketorolac Tromethamine			OFFSIDES
112	Letrozole			OFFSIDES
113	Lidoderm			OFFSIDES
114	Lithium Carbonate			OFFSIDES
115	Lubiprostone			OFFSIDES
116	Magnesium			OFFSIDES
117	Melphalan			OFFSIDES
118	Meperidine			OFFSIDES
119	Mepivacaine			OFFSIDES
120	Meropenem			OFFSIDES
121	Methadone			OFFSIDES
122	Methocarbamol			OFFSIDES
123	Methylprednisolone			OFFSIDES
124	Methyltestosterone			OFFSIDES
125	Metolazone			OFFSIDES
126	Metoprolol			OFFSIDES
127	Misoprostol			OFFSIDES
128	Mitoxantrone			OFFSIDES
129	Nabumetone			OFFSIDES
130	Naloxone			OFFSIDES
131	Niacin			OFFSIDES
132	Nicardipine			OFFSIDES
133	Nitrofurantoin			OFFSIDES
134	Nitroglycerin			OFFSIDES
135	Nizatidine			OFFSIDES
136	Norethindrone Acetate			OFFSIDES
137	Nortriptyline			OFFSIDES
138	Nystatin			OFFSIDES
139	Ofloxacin			OFFSIDES
140	Paclitaxel			OFFSIDES
141	Palonosetron			OFFSIDES
142	Pamidronate			OFFSIDES
143	Panipenem-betamipron			OFFSIDES
144	Penicillin G			OFFSIDES
145	Penicillin V			OFFSIDES
146	Penicillins			OFFSIDES
147	Pentoxifylline			OFFSIDES
148	Perindopril			OFFSIDES
149	Perphenazine			OFFSIDES
150	Piperacillin, Tazobactam Drug Combination		15155214	CTD
151	Piroxicam			OFFSIDES
152	Potassium			OFFSIDES
153	Prochlorperazine			OFFSIDES
154	Progesterone			OFFSIDES
155	Pyridoxine			OFFSIDES
156	Quetiapine Fumarate			OFFSIDES
157	Raloxifene Hydrochloride			OFFSIDES
158	Ramipril			OFFSIDES
159	Rifampin			OFFSIDES
160	Sertraline			OFFSIDES
161	Sodium Bicarbonate			OFFSIDES
162	Solifenacin Succinate			OFFSIDES
163	Streptomycin		4764162	CTD
164	Sulfamethoxazole			OFFSIDES
165	Sulindac			OFFSIDES
166	Tamoxifen			OFFSIDES
167	Tazobactam			OFFSIDES
168	Terazosin			OFFSIDES
169	Tetracycline			OFFSIDES
170	Thalidomide			OFFSIDES
171	Thiotepa			OFFSIDES
172	Thyroxine			OFFSIDES
173	Timolol			OFFSIDES
174	Trichlormethiazide			OFFSIDES
175	Triiodothyronine			OFFSIDES
176	Trimipramine			OFFSIDES
177	Vancomycin			OFFSIDES
178	Vecuronium Bromide			OFFSIDES
179	Vincristine			OFFSIDES
180	Vinorelbine			OFFSIDES
181	Vitamin B 12			OFFSIDES
182	Vitamin D			OFFSIDES
183	Warfarin			OFFSIDES
184	alfuzosin			OFFSIDES
185	azelastine			OFFSIDES
186	bicalutamide			OFFSIDES
187	candesartan cilexetil			OFFSIDES
188	carbidopa, levodopa drug combination			OFFSIDES
189	cefprozil			OFFSIDES
190	cefuroxime axetil			OFFSIDES
191	cerivastatin			OFFSIDES
192	chlorhexidine gluconate			OFFSIDES
193	dexamethasone acetate			OFFSIDES
194	dolasetron			OFFSIDES
195	exemestane			OFFSIDES
196	fludrocortisone acetate			OFFSIDES
197	gemcitabine			OFFSIDES
198	hydrocodone tartrate, ibuprofen drug combination			OFFSIDES
199	metaxalone			OFFSIDES
200	morphocycline		5678113	CTD
201	pimecrolimus			OFFSIDES
202	quinupristin-dalfopristin		15155214	CTD
203	repaglinide			OFFSIDES
204	reviparin			OFFSIDES
205	rizatriptan			OFFSIDES
206	rizatriptan			OFFSIDES
207	rofecoxib			OFFSIDES
208	salicylsalicylic acid			OFFSIDES
209	telavancin		15155214	CTD
210	tizanidine			OFFSIDES
211	valdecoxib			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Corynebacterium Infections	48.4%
2	Mycobacterium Infections	48.4%
3	Nocardia Infections	48.4%
4	Pulmonary Nocardiosis	48.4%
5	Diphtheria	36%
6	Leprosy	36%
7	Mycobacterium Infections, Nontuberculous	36%
8	Tuberculosis	36%
9	Mycobacterium abscessus Infection	36%
10	Clostridium Infections	34.4%
11	Listeriosis	34.4%
12	Staphylococcal Infections	34.4%
13	Streptococcal Infections	34.4%
14	Bacillaceae Infections	34.4%
15	Clostridium difficile infection	34.4%
16	Mycobacterium avium-intracellulare Infection	29.9%
17	Lymph Node Tuberculosis	29.9%
18	Tuberculosis, Miliary	29.9%
19	Tuberculosis, Multidrug-Resistant	29.9%
20	Leprosy, Multibacillary	29.9%
21	Latent Tuberculosis	29.9%
22	Borderline leprosy	26.8%
23	Leprosy, Lepromatous	26.8%
24	Tuberculoid leprosy	26.8%
25	Extensively Drug-Resistant Tuberculosis	26.8%
26	Gram-Negative Bacterial Infections	25.4%
27	Erysipelothrix infection	24.7%
28	Gas Gangrene	22.6%
29	Pneumococcal Infections	22.6%
30	Scarlet Fever	22.6%
31	Tetanus	22.6%
32	Erythrasma	21.7%
33	Tuberculosis, Gastrointestinal	20.7%
34	Tuberculosis, Central Nervous System	20%
35	Borrelia Infections	19.8%
36	Leptospirosis	19.8%
37	Joint Tuberculosis	17.7%
38	Tuberculosis, Osteoarticular	17.7%
39	Bone Tuberculosis	17.7%
40	Central Nervous System Bacterial Infections	17.1%
41	Impetigo	17.1%
42	Bacterial Vaginosis	16.6%
43	Mycoses	16.4%
44	Infection	16.4%
45	Erysipelas	16.2%
46	Staphylococcal Skin Infections	16.2%
47	Tuberculosis, Pulmonary	15.8%
48	Mycetoma	15.6%
49	Skin Diseases, Bacterial	15.1%
50	Bacteremia	14.9%
51	Bordetella Infections	14.8%
52	Brucellosis	14.8%
53	Campylobacter infection	14.8%
54	Enterobacteriaceae Infections	14.8%
55	Pseudomonas Infections	14.8%
56	Q Fever	14.8%
57	Vibrio Infections	14.8%
58	Helicobacter Infections	14.8%
59	Neisseriaceae Infections	14.8%
60	Burkholderia Infections	14.8%
61	Flavobacteriaceae Infections	14.8%
62	Moraxellaceae Infections	14.8%
63	Burkholderia cepacia Infection	14.8%
64	Lyme Disease	14.5%
65	Relapsing Fever	14.5%
66	Ecthyma	13.6%
67	Subacute Bacterial Endocarditis	13.6%
68	Human Ehrlichiosis	12.9%
69	Meningitis, Listeria	12.9%
70	Pneumonia, Bacterial	12.6%
71	Bacterial Endocarditis	12.2%
72	Tuberculosis, Meningeal	12.2%
73	Tuberculosis, Spinal	12.1%
74	Lyme Neuroborreliosis	12.1%
75	Rheumatic Fever	11.7%
76	Neurosyphilis	11.6%
77	Rheumatic Heart Disease	11.6%
78	Staphylococcal Scalded Skin Syndrome	11.5%
79	Enterocolitis, Pseudomembranous	11.3%
80	pseudomembranous colitis	11.3%
81	Japanese Spotted Fever	11.2%
82	Central Nervous System Infection	10.8%
83	Syphilis	10.6%
84	Meningitis, Pneumococcal	10.6%
85	Human anaplasmosis	10.3%
86	Erythema Chronicum Migrans	9.9%
87	Erythema Induratum	9.9%
88	Furunculosis	9.8%
89	furuncle	9.8%
90	Acinetobacter Infections	9.7%
91	Bacteroides Infections	9.7%
92	Cholera	9.7%
93	Escherichia coli Infections	9.7%
94	Haemophilus Infections	9.7%
95	Klebsiella Infections	9.7%
96	Meningococcal Infections	9.7%
97	Mycoplasma Infections	9.7%
98	Pasteurella Infections	9.7%
99	Proteus Infections	9.7%
100	Rickettsia Infections	9.7%
101	Salmonella infections	9.7%
102	Scrub Typhus	9.7%
103	Serratia Infections	9.7%
104	Ureaplasma Infections	9.7%
105	Botulism	9.3%
106	Tuberculosis, Renal	9.3%
107	carbuncle	9.2%
108	Chlamydia Infections	9.2%
109	Gonorrhea	9.2%
110	Rocky Mountain Spotted Fever	8.8%
111	Aspergillosis	8.5%
112	Candidiasis	8.5%
113	Coccidioidomycosis	8.5%
114	Histoplasmosis	8.5%
115	Paracoccidioidomycosis	8.5%
116	Pelvic Infection	8.5%
117	Wound Infection	8.5%
118	Zygomycosis	8.5%
119	Soft Tissue Infection	8.5%
120	Community-Acquired Infections	8.5%
121	Phaeohyphomycosis	8.5%
122	Pneumocystis Infections	8.5%
123	Ulcerative stomatitis	7.8%
124	Hidradenitis Suppurativa	7.6%
125	Pertussis	7.5%
126	Syphilis, Congenital	7.4%
127	Meningitis, Bacterial	7.4%
128	Hordeolum	7.3%
129	Bacterial conjunctivitis	7.2%
130	Psittacosis	7.2%
131	Paratyphoid Fever	7.2%
132	Plague	7.2%
133	Typhoid Fever	7.2%
134	TYPHUS	7.2%
135	Yersinia pseudotuberculosis Infections	7.2%
136	Bubonic Plague	7.2%
137	Meningitis, Haemophilus	6.7%
138	Dermatomycoses	6.7%
139	Rhinoscleroma	6.5%
140	Lymphogranuloma Venereum	6.4%
141	Eye Infection	6%
142	Respiratory Tract Infections	6%
143	Bone Diseases, Infectious	5.7%
144	Otomycosis	5.7%
145	Pregnancy Complications, Infectious	5.7%
146	Skin Diseases, Infectious	5.7%
147	Arthritis, Infectious	5.6%
148	Piedra	5.6%
149	Central Nervous System Fungal Infections	5.6%
150	Suppuration	5.6%
151	Ophthalmia Neonatorum	5.6%
152	Trachoma	5.6%
153	Cross Infection	5.6%
154	Septicemia	5.6%
155	Sepsis	5.6%
156	Candidiasis, Chronic Mucocutaneous	5.2%
157	Cutaneous Candidiasis	5.2%
158	Salmonella Infections, Animal	5.2%
159	Mucormycosis	4.9%
160	Neuroaspergillosis	4.9%
161	Fungemia	4.9%
162	Salmonella food poisoning	4.9%
163	Dysentery, Bacillary	4.8%
164	Opportunistic Infections	4.7%
165	Brain Abscess	4.7%
166	Panophthalmitis	4.4%
167	Lung Diseases, Fungal	4.3%
168	Candidemia	4.3%
169	Urinary tract infection	4.3%
170	Chromoblastomycosis	4.1%
171	Dermatophytosis	4.1%
172	Sporotrichosis	4.1%
173	Tinea	4.1%
174	Tinea Versicolor	4.1%
175	Trichophytosis	4.1%
176	Invasive Pulmonary Aspergillosis	4.1%
177	Hyalohyphomycosis	4.1%
178	Endotoxemia	4%
179	Cellulitis	4%
180	Blastomycosis	3.8%
181	Sexually Transmitted Diseases	3.5%
182	Oral candidiasis	3.4%
183	Endophthalmitis	3.4%
184	Peritonitis	3.4%
185	Osteomyelitis	3.3%
186	Periostitis	3.3%
187	Surgical Wound Infection	3.3%
188	Pulmonary Aspergillosis	3.3%
189	Bronchopulmonary Aspergillosis	3.3%
190	Abscess	3.3%
191	Adnexitis	3.3%
192	Empyema	3.3%
193	Pelvic Inflammatory Disease	3.3%
194	Meningitis, Cryptococcal	3.2%
195	Psoas Abscess	3.2%
196	Abdominal Abscess	3.2%
197	Fusariosis	2.8%
198	Waterhouse-Friderichsen Syndrome	2.7%
199	Superinfection	2.6%
200	Corneal Ulcer	2.5%
201	Puerperal Infection	2.5%
202	Spondylitis	2.5%
203	Appendicitis	2.5%
204	Bacteriuria	2.5%
205	Pyuria	2.5%
206	Meningitis, Fungal	2.5%
207	Pyomyositis	2.5%
208	Endotoxic shock	2.4%
209	Septic Shock	2.4%
210	Toxic Shock Syndrome	2.4%
211	Candidiasis, Vulvovaginal	2.4%
212	Tinea Capitis	2.3%
213	Onychomycosis	2.3%
214	Diverticulitis	2.2%
215	Lemierre Syndrome	2.1%
216	Arthritis, Reactive	1.9%
217	Tinea Pedis	1.9%
218	Toxoplasmosis, Cerebral	1.8%
219	Lung Abscess	1.7%
220	AIDS-Related Opportunistic Infections	1.7%
221	Liver Abscess	1.7%
222	Diverticulum	1.7%
223	Diverticulosis	1.7%
224	Discitis	1.6%
225	Mastoiditis	1.6%
226	Petrositis	1.6%
227	Retropharyngeal Abscess	1.3%
228	Epidural Abscess	1.3%
229	Peritonsillar Abscess	1.3%
230	Aspergillosis, Allergic Bronchopulmonary	1.1%
231	Liver Abscess, Amebic	0.7%

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