MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Plague

(UMLS:C0032064)

Definition:: An acute infectious disease caused by YERSINIA PESTIS that affects humans, wild rodents, and their ectoparasites. This condition persists due to its firm entrenchment in sylvatic rodent-flea ecosystems throughout the world. Bubonic plague is the most common form.
UMLS ID:: C0032064
MeSH ID:: D010930

Classification:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.400.310.980.745

Synonym(s)

Plague

Infection by Yersinia pestis

Pasteurella; infection, pestis

Pest

Pestilential fever

Plague, NOS

Plague, unspecified

Yersinia pestis disease

Yersinia pestis plague

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Levofloxacin	FAERS: 3		US FAERS
2	Ezetimibe	FAERS: 2		US FAERS
3	Amlodipine	FAERS: 1		US FAERS
4	Atorvastatin	FAERS: 1		US FAERS
5	LCZ 696	FAERS: 1		US FAERS
6	Lenalidomide	FAERS: 1		US FAERS
7	Liraglutide	FAERS: 1		US FAERS
8	Methotrexate	FAERS: 1		US FAERS
9	Praziquantel	FAERS: 1		US FAERS
10	Sunitinib	FAERS: 1		US FAERS
11	gemcitabine	FAERS: 1		US FAERS
12	Ciprofloxacin		28223382	CTD
13	Doxycycline		28223382	CTD
14	omadacycline		28223382	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Yersinia pseudotuberculosis Infections	49.2%
2	Escherichia coli Infections	36%
3	Klebsiella Infections	36%
4	Proteus Infections	36%
5	Salmonella infections	36%
6	Serratia Infections	36%
7	Bordetella Infections	28.5%
8	Brucellosis	28.5%
9	Campylobacter infection	28.5%
10	Pseudomonas Infections	28.5%
11	Q Fever	28.5%
12	Vibrio Infections	28.5%
13	Helicobacter Infections	28.5%
14	Neisseriaceae Infections	28.5%
15	Burkholderia Infections	28.5%
16	Flavobacteriaceae Infections	28.5%
17	Moraxellaceae Infections	28.5%
18	Burkholderia cepacia Infection	28.5%
19	Borrelia Infections	27.3%
20	Leptospirosis	27.3%
21	Paratyphoid Fever	23.8%
22	Typhoid Fever	23.8%
23	Gram-Positive Bacterial Infections	22.7%
24	Human Ehrlichiosis	22.5%
25	Lyme Disease	20.5%
26	Relapsing Fever	20.5%
27	Japanese Spotted Fever	18.6%
28	Dysentery, Bacillary	18.1%
29	Human anaplasmosis	17.9%
30	Salmonella Infections, Animal	17.2%
31	Acinetobacter Infections	16.8%
32	Bacteroides Infections	16.8%
33	Cholera	16.8%
34	Haemophilus Infections	16.8%
35	Meningococcal Infections	16.8%
36	Mycoplasma Infections	16.8%
37	Pasteurella Infections	16.8%
38	Rickettsia Infections	16.8%
39	Scrub Typhus	16.8%
40	Ureaplasma Infections	16.8%
41	Salmonella food poisoning	16.1%
42	Central Nervous System Bacterial Infections	15.3%
43	Mycoses	15.3%
44	Infection	15.3%
45	Bacterial Vaginosis	14.8%
46	Skin Diseases, Bacterial	13.4%
47	Bacteremia	13.2%
48	Lyme Neuroborreliosis	13.1%
49	Rocky Mountain Spotted Fever	12.9%
50	Actinomycetales Infections	12.2%
51	Clostridium Infections	12.2%
52	Listeriosis	12.2%
53	Staphylococcal Infections	12.2%
54	Streptococcal Infections	12.2%
55	Bacillaceae Infections	12.2%
56	Clostridium difficile infection	12.2%
57	Pneumonia, Bacterial	11.3%
58	Neurosyphilis	11.3%
59	Psittacosis	11.1%
60	TYPHUS	11.1%
61	Syphilis	11.1%
62	Bacterial Endocarditis	10.8%
63	Pertussis	10.8%
64	Chlamydia Infections	10.5%
65	Erythema Chronicum Migrans	10.5%
66	Gonorrhea	10.5%
67	Central Nervous System Infection	10.2%
68	Rhinoscleroma	10%
69	Ulcerative stomatitis	9.4%
70	Erysipelothrix infection	8.8%
71	Erysipelas	8.7%
72	Staphylococcal Skin Infections	8.7%
73	Syphilis, Congenital	8.2%
74	Erythrasma	7.7%
75	Aspergillosis	7.6%
76	Candidiasis	7.6%
77	Coccidioidomycosis	7.6%
78	Histoplasmosis	7.6%
79	Paracoccidioidomycosis	7.6%
80	Pelvic Infection	7.6%
81	Wound Infection	7.6%
82	Zygomycosis	7.6%
83	Soft Tissue Infection	7.6%
84	Community-Acquired Infections	7.6%
85	Phaeohyphomycosis	7.6%
86	Pneumocystis Infections	7.6%
87	Meningitis, Haemophilus	7.3%
88	Ecthyma	7.3%
89	Subacute Bacterial Endocarditis	7.3%
90	Actinomycosis	7.2%
91	Corynebacterium Infections	7.2%
92	Gas Gangrene	7.2%
93	Mycobacterium Infections	7.2%
94	Nocardia Infections	7.2%
95	Pneumococcal Infections	7.2%
96	Scarlet Fever	7.2%
97	Tetanus	7.2%
98	Pulmonary Nocardiosis	7.2%
99	Impetigo	6.9%
100	Lymphogranuloma Venereum	6.6%
101	Mycetoma	6.5%
102	Hidradenitis Suppurativa	6.2%
103	Meningitis, Bacterial	6.1%
104	Hordeolum	6%
105	Bacterial conjunctivitis	5.9%
106	Dermatomycoses	5.9%
107	Ophthalmia Neonatorum	5.8%
108	Trachoma	5.8%
109	Meningitis, Listeria	5.8%
110	Staphylococcal Scalded Skin Syndrome	5.4%
111	Eye Infection	5.4%
112	Respiratory Tract Infections	5.4%
113	Bone Diseases, Infectious	5.1%
114	Otomycosis	5.1%
115	Pregnancy Complications, Infectious	5.1%
116	Skin Diseases, Infectious	5.1%
117	Arthritis, Infectious	5%
118	Piedra	5%
119	Central Nervous System Fungal Infections	5%
120	Suppuration	5%
121	Cross Infection	5%
122	Septicemia	5%
123	Sepsis	5%
124	Meningitis, Pneumococcal	4.8%
125	Diphtheria	4.8%
126	Leprosy	4.8%
127	Mycobacterium Infections, Nontuberculous	4.8%
128	Tuberculosis	4.8%
129	Mycobacterium abscessus Infection	4.8%
130	Furunculosis	4.6%
131	furuncle	4.6%
132	Candidiasis, Chronic Mucocutaneous	4.2%
133	Cutaneous Candidiasis	4.2%
134	Opportunistic Infections	4.2%
135	Neuroaspergillosis	4.1%
136	Mucormycosis	4.1%
137	Fungemia	4.1%
138	Brain Abscess	4%
139	Lung Diseases, Fungal	3.9%
140	Joint Tuberculosis	3.9%
141	Tuberculosis, Osteoarticular	3.9%
142	Bone Tuberculosis	3.9%
143	Urinary tract infection	3.8%
144	carbuncle	3.8%
145	Rheumatic Fever	3.7%
146	Enterocolitis, Pseudomembranous	3.6%
147	pseudomembranous colitis	3.6%
148	Mycobacterium avium-intracellulare Infection	3.6%
149	Lymph Node Tuberculosis	3.6%
150	Tuberculosis, Miliary	3.6%
151	Tuberculosis, Multidrug-Resistant	3.6%
152	Leprosy, Multibacillary	3.6%
153	Latent Tuberculosis	3.6%
154	Tuberculosis, Meningeal	3.4%
155	Cellulitis	3.3%
156	Rheumatic Heart Disease	3.3%
157	Lemierre Syndrome	3.3%
158	Chromoblastomycosis	3.2%
159	Dermatophytosis	3.2%
160	Sporotrichosis	3.2%
161	Tinea	3.2%
162	Tinea Versicolor	3.2%
163	Trichophytosis	3.2%
164	Invasive Pulmonary Aspergillosis	3.2%
165	Hyalohyphomycosis	3.2%
166	Endotoxemia	3.2%
167	Panophthalmitis	3.2%
168	Candidemia	3.2%
169	Sexually Transmitted Diseases	3.2%
170	Blastomycosis	3%
171	Botulism	3%
172	Erythema Induratum	3%
173	Borderline leprosy	3%
174	Leprosy, Lepromatous	3%
175	Tuberculoid leprosy	3%
176	Extensively Drug-Resistant Tuberculosis	3%
177	Oral candidiasis	2.8%
178	Endophthalmitis	2.8%
179	Peritonitis	2.8%
180	Osteomyelitis	2.7%
181	Periostitis	2.7%
182	Surgical Wound Infection	2.7%
183	Pulmonary Aspergillosis	2.7%
184	Bronchopulmonary Aspergillosis	2.7%
185	Abscess	2.7%
186	Adnexitis	2.7%
187	Empyema	2.7%
188	Pelvic Inflammatory Disease	2.7%
189	Waterhouse-Friderichsen Syndrome	2.7%
190	Meningitis, Cryptococcal	2.6%
191	Tuberculosis, Gastrointestinal	2.5%
192	Psoas Abscess	2.4%
193	Abdominal Abscess	2.4%
194	Tuberculosis, Central Nervous System	2.4%
195	Tuberculosis, Spinal	2.2%
196	Superinfection	2.1%
197	Corneal Ulcer	2.1%
198	Puerperal Infection	2.1%
199	Spondylitis	2.1%
200	Appendicitis	2%
201	Bacteriuria	2%
202	Pyuria	2%
203	Meningitis, Fungal	2%
204	Pyomyositis	2%
205	Endotoxic shock	2%
206	Septic Shock	2%
207	Toxic Shock Syndrome	2%
208	Candidiasis, Vulvovaginal	2%
209	Fusariosis	2%
210	Tuberculosis, Pulmonary	1.9%
211	Tinea Capitis	1.6%
212	Onychomycosis	1.6%
213	Arthritis, Reactive	1.6%
214	Diverticulitis	1.6%
215	Toxoplasmosis, Cerebral	1.4%
216	AIDS-Related Opportunistic Infections	1.4%
217	Tinea Pedis	1.3%
218	Lung Abscess	1.3%
219	Diverticulum	1.2%
220	Diverticulosis	1.2%
221	Discitis	1.2%
222	Mastoiditis	1.2%
223	Petrositis	1.2%
224	Liver Abscess	1.1%
225	Tuberculosis, Renal	1%
226	Retropharyngeal Abscess	1%
227	Epidural Abscess	1%
228	Peritonsillar Abscess	1%
229	Aspergillosis, Allergic Bronchopulmonary	0.8%
230	Liver Abscess, Amebic	0.4%

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