MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Coccidioidomycosis

(UMLS:C0009186)

Definition:: Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN.
UMLS ID:: C0009186
MeSH ID:: D003047

Classification:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.703.203

Synonym(s)

Coccidioidomycosis

Coccidioidomycosis infection

Coccidioidomycosis, NOS

Coccidioidomycosis, unspecified

DESERT FEVER

FEVER, DESERT

FEVER, SAN JOAQUIN

FEVER, VALLEY

Infection by Coccidioides immitis

10.

Infection caused by Coccidioides immitis

11.

POSADAS-WERNICKE DISEASE

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Prednisone	FAERS: 8		US FAERS
2	apremilast	FAERS: 7		US FAERS
3	tofacitinib	FAERS: 5		US FAERS
4	NuvaRing	FAERS: 4		US FAERS
5	rofecoxib	FAERS: 4		OFFSIDES US FAERS
6	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 3		US FAERS
7	Bosentan	FAERS: 3		US FAERS
8	Clopidogrel	FAERS: 3		US FAERS
9	Methotrexate	FAERS: 3		US FAERS
10	Fentanyl	FAERS: 2		US FAERS
11	Levofloxacin	FAERS: 2		US FAERS
12	Raltegravir Potassium	FAERS: 2		US FAERS
13	Rivaroxaban	FAERS: 2		US FAERS
14	4-Aminopyridine	FAERS: 1		US FAERS
15	Alendronate	FAERS: 1		US FAERS
16	Azathioprine	FAERS: 1		OFFSIDES US FAERS
17	CH5424802	FAERS: 1		US FAERS
18	Exenatide	FAERS: 1		US FAERS
19	Fingolimod Hydrochloride	FAERS: 1		US FAERS
20	Fluconazole	FAERS: 1		OFFSIDES US FAERS
21	Fluticasone-Salmeterol Drug Combination	FAERS: 1		US FAERS
22	Insulin Detemir	FAERS: 1		US FAERS
23	Nitrofurantoin	FAERS: 1		US FAERS
24	Prednisolone	FAERS: 1		US FAERS
25	Ribavirin	FAERS: 1		US FAERS
26	Sitagliptin Phosphate	FAERS: 1		US FAERS
27	Tacrolimus	FAERS: 1		OFFSIDES US FAERS
28	Voriconazole	FAERS: 1		OFFSIDES US FAERS
29	benazepril	FAERS: 1		US FAERS
30	isavuconazole	FAERS: 1		US FAERS
31	tiotropium-olodaterol	FAERS: 1		US FAERS
32	Digoxin			OFFSIDES
33	Gadolinium			OFFSIDES
34	Glipizide			OFFSIDES
35	Itraconazole		14616112	CTD
36	Ketoconazole			OFFSIDES
37	Leflunomide			OFFSIDES
38	Mercaptopurine			OFFSIDES
39	Miconazole		984785	CTD
40	PCI 32765	Canada Vigilance: 1		Canada Vigilance
41	Progesterone			OFFSIDES
42	Pyridoxine			OFFSIDES
43	Temazepam			OFFSIDES
44	Vitamin B 12			OFFSIDES
45	Warfarin			OFFSIDES
46	liposomal amphotericin B		14657095	CTD
47	posaconazole		14657095	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Aspergillosis	42.9%
2	Candidiasis	42.9%
3	Histoplasmosis	42.9%
4	Paracoccidioidomycosis	42.9%
5	Zygomycosis	42.9%
6	Phaeohyphomycosis	42.9%
7	Pneumocystis Infections	42.9%
8	Mucormycosis	31%
9	Neuroaspergillosis	30.3%
10	Otomycosis	28.6%
11	Piedra	27.9%
12	Central Nervous System Fungal Infections	27.9%
13	Invasive Pulmonary Aspergillosis	27.5%
14	Candidiasis, Chronic Mucocutaneous	27.3%
15	Cutaneous Candidiasis	27.3%
16	Candidemia	27.2%
17	Dermatomycoses	25.9%
18	Bacterial Infections	23.1%
19	Infection	23.1%
20	Meningitis, Cryptococcal	21.8%
21	Lung Diseases, Fungal	21.4%
22	Oral candidiasis	20.9%
23	Pulmonary Aspergillosis	20.5%
24	Bronchopulmonary Aspergillosis	20.5%
25	Fungemia	20.1%
26	Blastomycosis	19.5%
27	Chromoblastomycosis	19.2%
28	Dermatophytosis	19.2%
29	Sporotrichosis	19.2%
30	Tinea	19.2%
31	Tinea Versicolor	19.2%
32	Trichophytosis	19.2%
33	Hyalohyphomycosis	19.2%
34	Fusariosis	16%
35	Mycetoma	15.8%
36	Meningitis, Fungal	15.1%
37	Central Nervous System Infection	15%
38	Candidiasis, Vulvovaginal	14.8%
39	Pelvic Infection	14.3%
40	Wound Infection	14.3%
41	Gram-Negative Bacterial Infections	14.3%
42	Gram-Positive Bacterial Infections	14.3%
43	Soft Tissue Infection	14.3%
44	Community-Acquired Infections	14.3%
45	Central Nervous System Bacterial Infections	14%
46	Borrelia Infections	13.6%
47	Leptospirosis	13.6%
48	Tinea Capitis	12.8%
49	Onychomycosis	12.8%
50	Lyme Disease	12.4%
51	Relapsing Fever	12.4%
52	Skin Diseases, Bacterial	12.1%
53	Bacteremia	11.9%
54	Panophthalmitis	11.8%
55	Human Ehrlichiosis	11.1%
56	Lyme Neuroborreliosis	10.6%
57	Tinea Pedis	10.6%
58	Erysipelas	10.6%
59	Staphylococcal Skin Infections	10.6%
60	Ulcerative stomatitis	10.5%
61	Japanese Spotted Fever	10.5%
62	Actinomycetales Infections	10.3%
63	Bordetella Infections	10.3%
64	Brucellosis	10.3%
65	Campylobacter infection	10.3%
66	Clostridium Infections	10.3%
67	Enterobacteriaceae Infections	10.3%
68	Listeriosis	10.3%
69	Pseudomonas Infections	10.3%
70	Q Fever	10.3%
71	Staphylococcal Infections	10.3%
72	Streptococcal Infections	10.3%
73	Vibrio Infections	10.3%
74	Helicobacter Infections	10.3%
75	Bacillaceae Infections	10.3%
76	Neisseriaceae Infections	10.3%
77	Burkholderia Infections	10.3%
78	Clostridium difficile infection	10.3%
79	Flavobacteriaceae Infections	10.3%
80	Moraxellaceae Infections	10.3%
81	Burkholderia cepacia Infection	10.3%
82	Impetigo	10.3%
83	Erythrasma	10.2%
84	Erythema Chronicum Migrans	10%
85	Eye Infection	10%
86	Respiratory Tract Infections	10%
87	Neurosyphilis	9.9%
88	Syphilis	9.8%
89	Bacterial Endocarditis	9.7%
90	Rocky Mountain Spotted Fever	9.6%
91	Bone Diseases, Infectious	9.5%
92	Pregnancy Complications, Infectious	9.5%
93	Skin Diseases, Infectious	9.5%
94	Pertussis	9.4%
95	Hidradenitis Suppurativa	9.4%
96	Arthritis, Infectious	9.3%
97	Suppuration	9.3%
98	Cross Infection	9.2%
99	Septicemia	9.2%
100	Sepsis	9.2%
101	Bacterial Vaginosis	9.1%
102	Staphylococcal Scalded Skin Syndrome	9.1%
103	Endotoxemia	9.1%
104	Brain Abscess	8.8%
105	Ecthyma	8.8%
106	Subacute Bacterial Endocarditis	8.8%
107	Human anaplasmosis	8.8%
108	Chlamydia Infections	8.8%
109	Gonorrhea	8.8%
110	Joint Tuberculosis	8.6%
111	Tuberculosis, Osteoarticular	8.6%
112	Bone Tuberculosis	8.6%
113	Acinetobacter Infections	8.5%
114	Actinomycosis	8.5%
115	Bacteroides Infections	8.5%
116	Cholera	8.5%
117	Corynebacterium Infections	8.5%
118	Escherichia coli Infections	8.5%
119	Gas Gangrene	8.5%
120	Haemophilus Infections	8.5%
121	Klebsiella Infections	8.5%
122	Meningococcal Infections	8.5%
123	Mycobacterium Infections	8.5%
124	Mycoplasma Infections	8.5%
125	Nocardia Infections	8.5%
126	Pasteurella Infections	8.5%
127	Pneumococcal Infections	8.5%
128	Proteus Infections	8.5%
129	Rickettsia Infections	8.5%
130	Salmonella infections	8.5%
131	Scarlet Fever	8.5%
132	Scrub Typhus	8.5%
133	Tetanus	8.5%
134	Psoas Abscess	8.5%
135	Serratia Infections	8.5%
136	Ureaplasma Infections	8.5%
137	Abdominal Abscess	8.5%
138	Pulmonary Nocardiosis	8.5%
139	carbuncle	8.4%
140	Aspergillosis, Allergic Bronchopulmonary	8.4%
141	Cellulitis	8.2%
142	Furunculosis	7.7%
143	furuncle	7.7%
144	Opportunistic Infections	7.7%
145	Diphtheria	7.6%
146	Leprosy	7.6%
147	Mycobacterium Infections, Nontuberculous	7.6%
148	Psittacosis	7.6%
149	Paratyphoid Fever	7.6%
150	Plague	7.6%
151	Syphilis, Congenital	7.6%
152	Tuberculosis	7.6%
153	Typhoid Fever	7.6%
154	TYPHUS	7.6%
155	Yersinia pseudotuberculosis Infections	7.6%
156	Bubonic Plague	7.6%
157	Mycobacterium abscessus Infection	7.6%
158	Lymphogranuloma Venereum	7.6%
159	Hordeolum	7.5%
160	Bacterial conjunctivitis	7.4%
161	Erysipelothrix infection	7.3%
162	Mycobacterium avium-intracellulare Infection	7.1%
163	Lymph Node Tuberculosis	7.1%
164	Tuberculosis, Miliary	7.1%
165	Tuberculosis, Multidrug-Resistant	7.1%
166	Leprosy, Multibacillary	7.1%
167	Latent Tuberculosis	7.1%
168	Urinary tract infection	7%
169	Endophthalmitis	7%
170	Peritonitis	7%
171	Pneumonia, Bacterial	6.9%
172	Borderline leprosy	6.9%
173	Leprosy, Lepromatous	6.9%
174	Tuberculoid leprosy	6.9%
175	Extensively Drug-Resistant Tuberculosis	6.9%
176	Osteomyelitis	6.8%
177	Periostitis	6.8%
178	Surgical Wound Infection	6.8%
179	Abscess	6.7%
180	Adnexitis	6.7%
181	Empyema	6.7%
182	Pelvic Inflammatory Disease	6.7%
183	Ophthalmia Neonatorum	6.6%
184	Trachoma	6.6%
185	Rhinoscleroma	6.6%
186	Meningitis, Listeria	6.6%
187	Meningitis, Haemophilus	6.2%
188	Meningitis, Pneumococcal	6.2%
189	Tuberculosis, Spinal	6%
190	Sexually Transmitted Diseases	5.8%
191	Erythema Induratum	5.6%
192	Diverticulitis	5.6%
193	Salmonella Infections, Animal	5.4%
194	Superinfection	5.3%
195	Corneal Ulcer	5.2%
196	Liver Abscess	5.1%
197	Rheumatic Heart Disease	5.1%
198	Puerperal Infection	5.1%
199	Spondylitis	5.1%
200	Appendicitis	5%
201	Bacteriuria	5%
202	Pyuria	5%
203	Meningitis, Bacterial	5%
204	Pyomyositis	5%
205	Salmonella food poisoning	5%
206	Endotoxic shock	5%
207	Septic Shock	5%
208	Toxic Shock Syndrome	5%
209	Tuberculosis, Meningeal	4.9%
210	Tuberculosis, Gastrointestinal	4.8%
211	Tuberculosis, Central Nervous System	4.7%
212	Lung Abscess	4.3%
213	Toxoplasmosis, Cerebral	4.3%
214	Rheumatic Fever	4.3%
215	Diverticulum	4.2%
216	Diverticulosis	4.2%
217	Discitis	4.1%
218	Enterocolitis, Pseudomembranous	4.1%
219	Mastoiditis	4.1%
220	Petrositis	4.1%
221	pseudomembranous colitis	4.1%
222	Dysentery, Bacillary	4.1%
223	Arthritis, Reactive	3.9%
224	Tuberculosis, Pulmonary	3.7%
225	AIDS-Related Opportunistic Infections	3.4%
226	Botulism	3.4%
227	Retropharyngeal Abscess	3.4%
228	Epidural Abscess	3.3%
229	Peritonsillar Abscess	3.3%
230	Waterhouse-Friderichsen Syndrome	2.8%
231	Liver Abscess, Amebic	2.4%
232	Tuberculosis, Renal	2.3%
233	Lemierre Syndrome	2.1%

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