MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Diphtheria

(UMLS:C0012546)

Definition:: A localized infection of mucous membranes or skin caused by toxigenic strains of CORYNEBACTERIUM DIPHTHERIAE. It is characterized by the presence of a pseudomembrane at the site of infection. DIPHTHERIA TOXIN, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects.
UMLS ID:: C0012546
MeSH ID:: D004165

Classification:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.410.040.246.388

Synonym(s)

Diphtheria

Corynebacterium diphtheriae; infection

DIPHTHERIA

Diphtheria, NOS

Diphtheria, unspecified

Infection caused by Corynebacterium diphtheriae

Infection due to Corynebacterium diphtheriae

diphtheria

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Baclofen	FAERS: 1	US FAERS
2	Digoxin	FAERS: 1	US FAERS
3	Pamidronate	FAERS: 1	US FAERS
4	Risperidone	FAERS: 1	US FAERS
5	ezogabine	FAERS: 1	US FAERS
6	patiromer	FAERS: 1	US FAERS
7	Ribavirin		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Actinomycosis	36%
2	Mycobacterium Infections	36%
3	Nocardia Infections	36%
4	Pulmonary Nocardiosis	36%
5	Clostridium Infections	28.5%
6	Listeriosis	28.5%
7	Staphylococcal Infections	28.5%
8	Streptococcal Infections	28.5%
9	Bacillaceae Infections	28.5%
10	Clostridium difficile infection	28.5%
11	Erythrasma	25.8%
12	Leprosy	23.8%
13	Mycobacterium Infections, Nontuberculous	23.8%
14	Tuberculosis	23.8%
15	Mycobacterium abscessus Infection	23.8%
16	Gram-Negative Bacterial Infections	22.7%
17	Erysipelothrix infection	20.5%
18	Mycobacterium avium-intracellulare Infection	17.8%
19	Lymph Node Tuberculosis	17.8%
20	Tuberculosis, Miliary	17.8%
21	Tuberculosis, Multidrug-Resistant	17.8%
22	Leprosy, Multibacillary	17.8%
23	Latent Tuberculosis	17.8%
24	Gas Gangrene	16.8%
25	Pneumococcal Infections	16.8%
26	Scarlet Fever	16.8%
27	Tetanus	16.8%
28	Borrelia Infections	16.4%
29	Leptospirosis	16.4%
30	Central Nervous System Bacterial Infections	15.3%
31	Mycoses	15.3%
32	Infection	15.3%
33	Bacterial Vaginosis	14.8%
34	Borderline leprosy	14.8%
35	Leprosy, Lepromatous	14.8%
36	Tuberculoid leprosy	14.8%
37	Extensively Drug-Resistant Tuberculosis	14.8%
38	Skin Diseases, Bacterial	13.4%
39	Bacteremia	13.2%
40	Erysipelas	12.6%
41	Staphylococcal Skin Infections	12.6%
42	Tuberculosis, Gastrointestinal	12.3%
43	Impetigo	12.2%
44	Bordetella Infections	12.2%
45	Brucellosis	12.2%
46	Campylobacter infection	12.2%
47	Enterobacteriaceae Infections	12.2%
48	Pseudomonas Infections	12.2%
49	Q Fever	12.2%
50	Vibrio Infections	12.2%
51	Helicobacter Infections	12.2%
52	Neisseriaceae Infections	12.2%
53	Burkholderia Infections	12.2%
54	Flavobacteriaceae Infections	12.2%
55	Moraxellaceae Infections	12.2%
56	Burkholderia cepacia Infection	12.2%
57	Tuberculosis, Central Nervous System	11.9%
58	Mycetoma	11.3%
59	Pneumonia, Bacterial	11.3%
60	Joint Tuberculosis	11.2%
61	Tuberculosis, Osteoarticular	11.2%
62	Bone Tuberculosis	11.2%
63	Bacterial Endocarditis	10.8%
64	Lyme Disease	10.8%
65	Relapsing Fever	10.8%
66	Ecthyma	10.6%
67	Subacute Bacterial Endocarditis	10.6%
68	Central Nervous System Infection	10.2%
69	Human Ehrlichiosis	9.6%
70	Meningitis, Listeria	9.6%
71	Tuberculosis, Pulmonary	9.4%
72	Lyme Neuroborreliosis	8.8%
73	Rheumatic Fever	8.7%
74	Neurosyphilis	8.7%
75	Enterocolitis, Pseudomembranous	8.4%
76	pseudomembranous colitis	8.4%
77	Syphilis	8.3%
78	Japanese Spotted Fever	8%
79	Staphylococcal Scalded Skin Syndrome	8%
80	Rheumatic Heart Disease	7.7%
81	Human anaplasmosis	7.7%
82	Aspergillosis	7.6%
83	Candidiasis	7.6%
84	Coccidioidomycosis	7.6%
85	Histoplasmosis	7.6%
86	Paracoccidioidomycosis	7.6%
87	Pelvic Infection	7.6%
88	Wound Infection	7.6%
89	Zygomycosis	7.6%
90	Soft Tissue Infection	7.6%
91	Community-Acquired Infections	7.6%
92	Phaeohyphomycosis	7.6%
93	Pneumocystis Infections	7.6%
94	Tuberculosis, Meningeal	7.4%
95	Meningitis, Pneumococcal	7.3%
96	Chlamydia Infections	7.3%
97	Erythema Chronicum Migrans	7.3%
98	Gonorrhea	7.3%
99	Acinetobacter Infections	7.2%
100	Bacteroides Infections	7.2%
101	Cholera	7.2%
102	Escherichia coli Infections	7.2%
103	Haemophilus Infections	7.2%
104	Klebsiella Infections	7.2%
105	Meningococcal Infections	7.2%
106	Mycoplasma Infections	7.2%
107	Pasteurella Infections	7.2%
108	Proteus Infections	7.2%
109	Rickettsia Infections	7.2%
110	Salmonella infections	7.2%
111	Scrub Typhus	7.2%
112	Serratia Infections	7.2%
113	Ureaplasma Infections	7.2%
114	Botulism	7%
115	Tuberculosis, Spinal	7%
116	Furunculosis	6.8%
117	furuncle	6.8%
118	Hidradenitis Suppurativa	6.2%
119	Ulcerative stomatitis	6.1%
120	Meningitis, Bacterial	6.1%
121	Erythema Induratum	6%
122	Hordeolum	6%
123	Bacterial conjunctivitis	5.9%
124	Dermatomycoses	5.9%
125	Pertussis	5.8%
126	carbuncle	5.7%
127	Rocky Mountain Spotted Fever	5.5%
128	Eye Infection	5.4%
129	Respiratory Tract Infections	5.4%
130	Bone Diseases, Infectious	5.1%
131	Otomycosis	5.1%
132	Pregnancy Complications, Infectious	5.1%
133	Skin Diseases, Infectious	5.1%
134	Tuberculosis, Renal	5.1%
135	Arthritis, Infectious	5%
136	Piedra	5%
137	Central Nervous System Fungal Infections	5%
138	Suppuration	5%
139	Rhinoscleroma	5%
140	Cross Infection	5%
141	Septicemia	5%
142	Sepsis	5%
143	Syphilis, Congenital	4.9%
144	Meningitis, Haemophilus	4.8%
145	Psittacosis	4.8%
146	Paratyphoid Fever	4.8%
147	Plague	4.8%
148	Typhoid Fever	4.8%
149	TYPHUS	4.8%
150	Yersinia pseudotuberculosis Infections	4.8%
151	Bubonic Plague	4.8%
152	Lymphogranuloma Venereum	4.5%
153	Candidiasis, Chronic Mucocutaneous	4.2%
154	Cutaneous Candidiasis	4.2%
155	Opportunistic Infections	4.2%
156	Neuroaspergillosis	4.1%
157	Mucormycosis	4.1%
158	Fungemia	4.1%
159	Brain Abscess	4%
160	Ophthalmia Neonatorum	3.9%
161	Trachoma	3.9%
162	Lung Diseases, Fungal	3.9%
163	Urinary tract infection	3.8%
164	Dysentery, Bacillary	3.6%
165	Salmonella Infections, Animal	3.4%
166	Cellulitis	3.3%
167	Chromoblastomycosis	3.2%
168	Dermatophytosis	3.2%
169	Sporotrichosis	3.2%
170	Tinea	3.2%
171	Tinea Versicolor	3.2%
172	Trichophytosis	3.2%
173	Invasive Pulmonary Aspergillosis	3.2%
174	Hyalohyphomycosis	3.2%
175	Salmonella food poisoning	3.2%
176	Endotoxemia	3.2%
177	Panophthalmitis	3.2%
178	Candidemia	3.2%
179	Sexually Transmitted Diseases	3.2%
180	Blastomycosis	3%
181	Oral candidiasis	2.8%
182	Endophthalmitis	2.8%
183	Peritonitis	2.8%
184	Osteomyelitis	2.7%
185	Periostitis	2.7%
186	Surgical Wound Infection	2.7%
187	Pulmonary Aspergillosis	2.7%
188	Bronchopulmonary Aspergillosis	2.7%
189	Abscess	2.7%
190	Adnexitis	2.7%
191	Empyema	2.7%
192	Pelvic Inflammatory Disease	2.7%
193	Meningitis, Cryptococcal	2.6%
194	Psoas Abscess	2.4%
195	Abdominal Abscess	2.4%
196	Superinfection	2.1%
197	Corneal Ulcer	2.1%
198	Puerperal Infection	2.1%
199	Spondylitis	2.1%
200	Appendicitis	2%
201	Bacteriuria	2%
202	Pyuria	2%
203	Meningitis, Fungal	2%
204	Pyomyositis	2%
205	Endotoxic shock	2%
206	Septic Shock	2%
207	Toxic Shock Syndrome	2%
208	Candidiasis, Vulvovaginal	2%
209	Fusariosis	2%
210	Waterhouse-Friderichsen Syndrome	1.7%
211	Tinea Capitis	1.6%
212	Onychomycosis	1.6%
213	Arthritis, Reactive	1.6%
214	Diverticulitis	1.6%
215	Toxoplasmosis, Cerebral	1.4%
216	Lemierre Syndrome	1.4%
217	AIDS-Related Opportunistic Infections	1.4%
218	Tinea Pedis	1.3%
219	Lung Abscess	1.3%
220	Diverticulum	1.2%
221	Diverticulosis	1.2%
222	Discitis	1.2%
223	Mastoiditis	1.2%
224	Petrositis	1.2%
225	Liver Abscess	1.1%
226	Retropharyngeal Abscess	1%
227	Epidural Abscess	1%
228	Peritonsillar Abscess	1%
229	Aspergillosis, Allergic Bronchopulmonary	0.8%
230	Liver Abscess, Amebic	0.4%

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