MetaADEDB 2.0 @ LMMD
Lyme Disease
(UMLS:C0024198)
Definition:
An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.
UMLS ID:
C0024198
MeSH ID:
D008193
Classification:
Name:
Bacterial Infections and Mycoses
MeSH Tree Number(s):
C01.252.400.155.569|C01.252.400.825.480|C01.252.847.193.569
Synonym(s)
1.
Lyme Disease
2.
Borrelia
3.
Borrelia Burgdorferi Infection
4.
Borrelia burgdorferi Infection
5.
Disease;lyme
6.
Infection by Borrelia burgdorferi
7.
Infection due to Borrelia burgdorferi sensu lato
8.
LYME DISEASE
9.
Lyme borreliosis
10.
Lyme disease
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1Fingolimod HydrochlorideFAERS: 25US FAERS
24-hydroxybutyric acidFAERS: 21US FAERS
3PregabalinFAERS: 15US FAERS
4Dimethyl FumarateFAERS: 13US FAERS
5LenalidomideFAERS: 13US FAERS
6NuvaRingFAERS: 13US FAERS
7IsotretinoinFAERS: 12US FAERS
8TeriparatideFAERS: 11US FAERS
9AlendronateFAERS: 10US FAERS
10Glatiramer AcetateFAERS: 10US FAERS
11Duloxetine HydrochlorideFAERS: 9US FAERS
12tofacitinibFAERS: 9
Canada Vigilance: 2		Canada Vigilance
US FAERS
13apremilastFAERS: 7US FAERS
14DoxycyclineFAERS: 69332695
17103211		CTD
US FAERS
15Quetiapine FumarateFAERS: 6US FAERS
16VareniclineFAERS: 6US FAERS
17CelecoxibFAERS: 5US FAERS
18NorgestrelFAERS: 5US FAERS
19OmeprazoleFAERS: 5US FAERS
20ambrisentanFAERS: 5US FAERS
21teriflunomideFAERS: 5US FAERS
224-AminopyridineFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
23AlprazolamFAERS: 4US FAERS
24AtorvastatinFAERS: 4US FAERS
25AzithromycinFAERS: 4US FAERS
26BosentanFAERS: 4US FAERS
27IbuprofenFAERS: 4US FAERS
28MethylphenidateFAERS: 4OFFSIDES
US FAERS
29OxycodoneFAERS: 4US FAERS
30ValsartanFAERS: 4US FAERS
31rofecoxibFAERS: 4US FAERS
32AtovaquoneFAERS: 3OFFSIDES
US FAERS
33ClozapineFAERS: 3US FAERS
34HydroxychloroquineFAERS: 3US FAERS
35LamotrigineFAERS: 3US FAERS
36MDV 3100FAERS: 3US FAERS
37NaltrexoneFAERS: 3US FAERS
38RivaroxabanFAERS: 3US FAERS
39pomalidomideFAERS: 3US FAERS
404-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideFAERS: 2US FAERS
41BortezomibFAERS: 2US FAERS
42DeferasiroxFAERS: 2US FAERS
43Emtricitabine, Rilpivirine, Tenofovir Drug CombinationFAERS: 2US FAERS
44Estrogens, Conjugated (USP)FAERS: 2US FAERS
45FentanylFAERS: 2OFFSIDES
US FAERS
46GabapentinFAERS: 2US FAERS
47Insulin GlargineFAERS: 2US FAERS
48LevofloxacinFAERS: 2US FAERS
49Lurasidone HydrochlorideFAERS: 2US FAERS
50Penicillin G BenzathineFAERS: 2US FAERS
51Quetiapine FumarateFAERS: 2US FAERS
52Rosuvastatin CalciumFAERS: 2US FAERS
53Ruxolitinib phosphateFAERS: 2US FAERS
54TerbinafineFAERS: 2OFFSIDES
US FAERS
55ThyroxineFAERS: 2US FAERS
56ValacyclovirFAERS: 2US FAERS
57lumacaftor, ivacaftor drug combinationFAERS: 2US FAERS
58macitentanFAERS: 2US FAERS
59obeticholic acidFAERS: 2US FAERS
60paricalcitolFAERS: 2US FAERS
61AlbuterolFAERS: 1US FAERS
62AmlodipineFAERS: 1US FAERS
63AmlodipineFAERS: 1US FAERS
64AnastrozoleFAERS: 1US FAERS
65Atomoxetine HydrochlorideFAERS: 1US FAERS
66BaclofenFAERS: 1US FAERS
67Bendamustine HydrochlorideFAERS: 1US FAERS
68BuprenorphineFAERS: 1US FAERS
69CeftriaxoneFAERS: 1

View details

1632349
7995584
8013837
8309205
8419791
8429594
16485100
 		CTD
US FAERS
70CephalexinFAERS: 1OFFSIDES
US FAERS
71CiprofloxacinFAERS: 1US FAERS
72ClarithromycinFAERS: 1US FAERS
73CopperFAERS: 1US FAERS
74CyclophosphamideFAERS: 1US FAERS
75DabigatranFAERS: 1US FAERS
76DasatinibFAERS: 1US FAERS
77DaunorubicinFAERS: 1US FAERS
78DichlorphenamideFAERS: 1US FAERS
79DroxidopaFAERS: 1US FAERS
80EplerenoneFAERS: 1US FAERS
81Erlotinib HydrochlorideFAERS: 1US FAERS
82EsomeprazoleFAERS: 1US FAERS
83EzetimibeFAERS: 1US FAERS
84FluconazoleFAERS: 1US FAERS
85Fluticasone-Salmeterol Drug CombinationFAERS: 1US FAERS
86Imatinib MesylateFAERS: 1US FAERS
87LCZ 696FAERS: 1US FAERS
88LetrozoleFAERS: 1US FAERS
89LiraglutideFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
90Lisdexamfetamine DimesylateFAERS: 1US FAERS
91Medroxyprogesterone AcetateFAERS: 1US FAERS
92MelphalanFAERS: 1US FAERS
93MethotrexateFAERS: 1US FAERS
94MethotrexateFAERS: 1US FAERS
95MethylphenidateFAERS: 1US FAERS
96MetoprololFAERS: 1US FAERS
97MinocyclineFAERS: 1US FAERS
98Mometasone FuroateFAERS: 1US FAERS
99Mycophenolic AcidFAERS: 1US FAERS
100NaproxenFAERS: 1US FAERS
101Nexium 24hrFAERS: 1US FAERS
102NiacinFAERS: 1US FAERS
103OctreotideFAERS: 1US FAERS
104OlanzapineFAERS: 1US FAERS
105Ortho EvraFAERS: 1US FAERS
106PhenytoinFAERS: 1US FAERS
107PraziquantelFAERS: 1US FAERS
108PrednisoneFAERS: 1US FAERS
109QuinineFAERS: 1US FAERS
110RanitidineFAERS: 1US FAERS
111RifaximinFAERS: 1US FAERS
112Risedronic AcidFAERS: 1US FAERS
113SimvastatinFAERS: 1US FAERS
114Sitagliptin PhosphateFAERS: 1US FAERS
115SorafenibFAERS: 1US FAERS
116TacrolimusFAERS: 1US FAERS
117TadalafilFAERS: 1US FAERS
118TapentadolFAERS: 1US FAERS
119TenofovirFAERS: 1US FAERS
120TestosteroneFAERS: 1US FAERS
121ThalidomideFAERS: 1US FAERS
122ThyroxineFAERS: 1US FAERS
123TioproninFAERS: 1US FAERS
124TopiramateFAERS: 1US FAERS
125TramadolFAERS: 1US FAERS
126Trimethoprim, Sulfamethoxazole Drug CombinationFAERS: 1US FAERS
127ValganciclovirFAERS: 1US FAERS
128Venlafaxine HydrochlorideFAERS: 1US FAERS
129ZolpidemFAERS: 1OFFSIDES
US FAERS
130apixabanFAERS: 1US FAERS
131cefuroxime axetilFAERS: 1OFFSIDES
US FAERS
132deflazacortFAERS: 1US FAERS
133eletriptanFAERS: 1OFFSIDES
US FAERS
134eltrombopagFAERS: 1US FAERS
135empagliflozinFAERS: 1US FAERS
136etonogestrelFAERS: 1US FAERS
137ivacaftorFAERS: 1US FAERS
138lenvatinibFAERS: 1US FAERS
139montelukastFAERS: 1US FAERS
140norgestimate, ethinyl estradiol drug combinationFAERS: 1US FAERS
141olaparibFAERS: 1US FAERS
142pazopanibFAERS: 1US FAERS
143pirfenidoneFAERS: 1US FAERS
144reviparinFAERS: 1US FAERS
145sapropterinFAERS: 1US FAERS
146semaglutideFAERS: 1US FAERS
147teduglutideFAERS: 1US FAERS
148valbenazineFAERS: 1US FAERS
149ziprasidoneFAERS: 1US FAERS
150zolmitriptanFAERS: 1US FAERS
151AcebutololOFFSIDES
152AmitriptylineOFFSIDES
153Aspirin-oxycodone hydrochloride-oxycodone terephthalate combinationOFFSIDES
154CarisoprodolOFFSIDES
155EconazoleOFFSIDES
156FluoxetineOFFSIDES
157FosinoprilOFFSIDES
158ImipramineOFFSIDES
159MemantineOFFSIDES
160MorphineOFFSIDES
161OfloxacinOFFSIDES
162PantoprazoleOFFSIDES
163PenicillinsSIDER
164PindololOFFSIDES
165Pyridostigmine BromideOFFSIDES
166Salmeterol XinafoateOFFSIDES
167SertralineOFFSIDES
168VerapamilOFFSIDES
169Zoledronic AcidOFFSIDES
170atovaquone, proguanil drug combinationOFFSIDES
171candesartan cilexetilOFFSIDES
172candesartanOFFSIDES
173montelukastOFFSIDES
Similar ADE(s)
NameSemantic Similarity
1Relapsing Fever76.3%
2Leptospirosis58.8%
3Human Ehrlichiosis54.2%
4Japanese Spotted Fever48.6%
5Human anaplasmosis46.9%
6Bordetella Infections41.5%
7Brucellosis41.5%
8Campylobacter infection41.5%
9Enterobacteriaceae Infections41.5%
10Pseudomonas Infections41.5%
11Q Fever41.5%
12Vibrio Infections41.5%
13Helicobacter Infections41.5%
14Neisseriaceae Infections41.5%
15Burkholderia Infections41.5%
16Flavobacteriaceae Infections41.5%
17Moraxellaceae Infections41.5%
18Burkholderia cepacia Infection41.5%
19Rocky Mountain Spotted Fever37.6%
20Gram-Positive Bacterial Infections37.2%
21Central Nervous System Bacterial Infections33.5%
22Syphilis33.4%
23Neurosyphilis33.2%
24Borrelia Infections31.4%
25Skin Diseases, Bacterial29.8%
26Bacteremia29.6%
27Bacterial Vaginosis29.5%
28Lyme Disease28%
29Acinetobacter Infections27.4%
30Bacteroides Infections27.4%
31Cholera27.4%
32Escherichia coli Infections27.4%
33Haemophilus Infections27.4%
34Klebsiella Infections27.4%
35Meningococcal Infections27.4%
36Mycoplasma Infections27.4%
37Pasteurella Infections27.4%
38Proteus Infections27.4%
39Rickettsia Infections27.4%
40Salmonella infections27.4%
41Scrub Typhus27.4%
42Serratia Infections27.4%
43Ureaplasma Infections27.4%
44Chlamydia Infections27.1%
45Gonorrhea27.1%
46Lyme Neuroborreliosis26.6%
47Bacterial Endocarditis25.8%
48Pneumonia, Bacterial24.9%
49Syphilis, Congenital24.5%
50Pertussis23.6%
51Erysipelas23.6%
52Staphylococcal Skin Infections23.6%
53Erythema Chronicum Migrans23.3%
54Mycoses23.1%
55Infection23.1%
56Ulcerative stomatitis22%
57Actinomycetales Infections22%
58Clostridium Infections22%
59Listeriosis22%
60Staphylococcal Infections22%
61Streptococcal Infections22%
62Bacillaceae Infections22%
63Clostridium difficile infection22%
64Impetigo21.6%
65Erythrasma21.5%
66Ecthyma20.7%
67Subacute Bacterial Endocarditis20.7%
68Psittacosis20.5%
69Paratyphoid Fever20.5%
70Plague20.5%
71Typhoid Fever20.5%
72TYPHUS20.5%
73Yersinia pseudotuberculosis Infections20.5%
74Bubonic Plague20.5%
75Meningitis, Haemophilus20%
76Mycetoma19.9%
77Rhinoscleroma19.5%
78Lymphogranuloma Venereum19.2%
79Central Nervous System Infection18.6%
80Erysipelothrix infection18.4%
81Dysentery, Bacillary18.3%
82Ophthalmia Neonatorum17.3%
83Trachoma17.3%
84Salmonella Infections, Animal17.2%
85Hidradenitis Suppurativa17.1%
86Meningitis, Listeria16.6%
87Salmonella food poisoning16.5%
88Staphylococcal Scalded Skin Syndrome16.5%
89Hordeolum15.6%
90Bacterial conjunctivitis15.4%
91Meningitis, Bacterial14.7%
92Furunculosis14.6%
93furuncle14.6%
94Actinomycosis14.5%
95Corynebacterium Infections14.5%
96Gas Gangrene14.5%
97Mycobacterium Infections14.5%
98Nocardia Infections14.5%
99Pneumococcal Infections14.5%
100Scarlet Fever14.5%
101Tetanus14.5%
102Pulmonary Nocardiosis14.5%
103Meningitis, Pneumococcal14.4%
104Dermatomycoses13.3%
105carbuncle13%
106Aspergillosis12.4%
107Candidiasis12.4%
108Coccidioidomycosis12.4%
109Histoplasmosis12.4%
110Paracoccidioidomycosis12.4%
111Pelvic Infection12.4%
112Wound Infection12.4%
113Zygomycosis12.4%
114Gram-Negative Bacterial Infections12.4%
115Soft Tissue Infection12.4%
116Community-Acquired Infections12.4%
117Phaeohyphomycosis12.4%
118Pneumocystis Infections12.4%
119Tuberculosis, Meningeal11.3%
120Candidiasis, Chronic Mucocutaneous11.2%
121Cutaneous Candidiasis11.2%
122Joint Tuberculosis11%
123Tuberculosis, Osteoarticular11%
124Bone Tuberculosis11%
125Diphtheria10.8%
126Leprosy10.8%
127Mycobacterium Infections, Nontuberculous10.8%
128Tuberculosis10.8%
129Mycobacterium abscessus Infection10.8%
130Panophthalmitis10.6%
131Erythema Induratum10.6%
132Eye Infection10.3%
133Respiratory Tract Infections10.3%
134Bone Diseases, Infectious10.1%
135Otomycosis10.1%
136Pregnancy Complications, Infectious10.1%
137Skin Diseases, Infectious10.1%
138Arthritis, Infectious9.9%
139Piedra9.9%
140Central Nervous System Fungal Infections9.9%
141Suppuration9.9%
142Brain Abscess9.9%
143Rheumatic Fever9.9%
144Cross Infection9.9%
145Septicemia9.9%
146Sepsis9.9%
147Neuroaspergillosis9.8%
148Fungemia9.8%
149Enterocolitis, Pseudomembranous9.7%
150pseudomembranous colitis9.7%
151Candidemia9.6%
152Waterhouse-Friderichsen Syndrome9.3%
153Lemierre Syndrome9.3%
154Mycobacterium avium-intracellulare Infection9%
155Lymph Node Tuberculosis9%
156Tuberculosis, Miliary9%
157Tuberculosis, Multidrug-Resistant9%
158Leprosy, Multibacillary9%
159Latent Tuberculosis9%
160Opportunistic Infections8.9%
161Rheumatic Heart Disease8.9%
162Blastomycosis8.7%
163Botulism8.5%
164Cellulitis8.5%
165Lung Diseases, Fungal8.5%
166Urinary tract infection8.4%
167Chromoblastomycosis8.1%
168Dermatophytosis8.1%
169Borderline leprosy8.1%
170Leprosy, Lepromatous8.1%
171Tuberculoid leprosy8.1%
172Sporotrichosis8.1%
173Tinea8.1%
174Tinea Versicolor8.1%
175Trichophytosis8.1%
176Invasive Pulmonary Aspergillosis8.1%
177Hyalohyphomycosis8.1%
178Extensively Drug-Resistant Tuberculosis8.1%
179Endotoxemia8.1%
180Tuberculosis, Spinal7.4%
181Sexually Transmitted Diseases7.4%
182Tuberculosis, Gastrointestinal7.4%
183Mucormycosis7.3%
184Tuberculosis, Central Nervous System7.2%
185Meningitis, Cryptococcal6.9%
186Tuberculosis, Pulmonary6.2%
187Oral candidiasis6%
188Endophthalmitis6%
189Peritonitis6%
190Osteomyelitis5.9%
191Periostitis5.9%
192Surgical Wound Infection5.9%
193Pulmonary Aspergillosis5.9%
194Bronchopulmonary Aspergillosis5.9%
195Abscess5.8%
196Adnexitis5.8%
197Empyema5.8%
198Pelvic Inflammatory Disease5.8%
199Fusariosis5.6%
200Superinfection5%
201Corneal Ulcer5%
202Puerperal Infection4.9%
203Spondylitis4.9%
204Appendicitis4.9%
205Bacteriuria4.9%
206Pyuria4.9%
207Meningitis, Fungal4.9%
208Pyomyositis4.9%
209Endotoxic shock4.9%
210Septic Shock4.9%
211Toxic Shock Syndrome4.9%
212Tinea Capitis4.8%
213Onychomycosis4.8%
214Psoas Abscess4.8%
215Abdominal Abscess4.8%
216Candidiasis, Vulvovaginal4.8%
217Toxoplasmosis, Cerebral4.4%
218Tinea Pedis4.2%
219Tuberculosis, Renal4.2%
220Arthritis, Reactive4.1%
221Diverticulitis3.9%
222AIDS-Related Opportunistic Infections3.7%
223Lung Abscess3.3%
224Diverticulum3.3%
225Diverticulosis3.3%
226Discitis3.2%
227Mastoiditis3.2%
228Petrositis3.2%
229Liver Abscess3%
230Retropharyngeal Abscess2.8%
231Epidural Abscess2.8%
232Peritonsillar Abscess2.8%
233Aspergillosis, Allergic Bronchopulmonary2.5%
234Liver Abscess, Amebic1.5%
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