MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Brucellosis

(UMLS:C0006309)

Definition:: Infection caused by bacteria of the genus BRUCELLA mainly involving the MONONUCLEAR PHAGOCYTE SYSTEM. This condition is characterized by fever, weakness, malaise, and weight loss.
UMLS ID:: C0006309
MeSH ID:: D002006

Classification:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.400.167

Synonym(s)

Brucellosis

BRUCELLOSIS

Bruce

Brucella; infection

Brucellosis, NOS

Brucellosis, unspecified

Cyprus fever

FEVER, MALTA

FEVER, MEDITERRANEAN

10.

FEVER, UNDULANT

11.

Gibraltar fever

12.

Gibraltar; fever

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Doxycycline	FAERS: 3		US FAERS
2	Teriparatide	FAERS: 2		US FAERS
3	Acyclovir	FAERS: 1		US FAERS
4	Azithromycin	FAERS: 1		US FAERS
5	BMS201038	FAERS: 1		US FAERS
6	Diovan Hct	FAERS: 1		US FAERS
7	Risperidone	FAERS: 1		US FAERS
8	Tacrolimus	FAERS: 1		US FAERS
9	Doxycycline			OFFSIDES
10	Fludrocortisone			OFFSIDES
11	Ketoconazole		12183525	CTD
12	Rifampin		16236685 18445910 19861876	CTD
13	Tetracycline		16236685	CTD
14	fludarabine			OFFSIDES
15	rizatriptan			OFFSIDES
16	rizatriptan			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Bordetella Infections	46.7%
2	Campylobacter infection	46.7%
3	Enterobacteriaceae Infections	46.7%
4	Pseudomonas Infections	46.7%
5	Q Fever	46.7%
6	Vibrio Infections	46.7%
7	Helicobacter Infections	46.7%
8	Neisseriaceae Infections	46.7%
9	Burkholderia Infections	46.7%
10	Flavobacteriaceae Infections	46.7%
11	Moraxellaceae Infections	46.7%
12	Burkholderia cepacia Infection	46.7%
13	Human Ehrlichiosis	45.7%
14	Borrelia Infections	44.4%
15	Leptospirosis	44.4%
16	Japanese Spotted Fever	41.6%
17	Lyme Disease	41.5%
18	Relapsing Fever	41.5%
19	Human anaplasmosis	36.2%
20	Rocky Mountain Spotted Fever	35.7%
21	Acinetobacter Infections	34.4%
22	Bacteroides Infections	34.4%
23	Cholera	34.4%
24	Escherichia coli Infections	34.4%
25	Haemophilus Infections	34.4%
26	Klebsiella Infections	34.4%
27	Meningococcal Infections	34.4%
28	Mycoplasma Infections	34.4%
29	Pasteurella Infections	34.4%
30	Proteus Infections	34.4%
31	Rickettsia Infections	34.4%
32	Salmonella infections	34.4%
33	Scrub Typhus	34.4%
34	Serratia Infections	34.4%
35	Ureaplasma Infections	34.4%
36	Gram-Positive Bacterial Infections	31%
37	Lyme Neuroborreliosis	29.4%
38	Psittacosis	28.5%
39	Paratyphoid Fever	28.5%
40	Plague	28.5%
41	Typhoid Fever	28.5%
42	TYPHUS	28.5%
43	Yersinia pseudotuberculosis Infections	28.5%
44	Bubonic Plague	28.5%
45	Neurosyphilis	24%
46	Erythema Chronicum Migrans	23.3%
47	Pertussis	21%
48	Syphilis	20.9%
49	Central Nervous System Bacterial Infections	20.7%
50	Syphilis, Congenital	20.7%
51	Salmonella Infections, Animal	20.5%
52	Bacterial Vaginosis	20.1%
53	Actinomycetales Infections	20%
54	Clostridium Infections	20%
55	Listeriosis	20%
56	Staphylococcal Infections	20%
57	Streptococcal Infections	20%
58	Bacillaceae Infections	20%
59	Clostridium difficile infection	20%
60	Chlamydia Infections	19.5%
61	Gonorrhea	19.5%
62	Ulcerative stomatitis	19.4%
63	Salmonella food poisoning	19.1%
64	Skin Diseases, Bacterial	18.6%
65	Mycoses	18.5%
66	Infection	18.5%
67	Bacteremia	18.4%
68	Meningitis, Haemophilus	17.1%
69	Dysentery, Bacillary	17.1%
70	Erysipelas	15.7%
71	Staphylococcal Skin Infections	15.7%
72	Lymphogranuloma Venereum	15.5%
73	Pneumonia, Bacterial	15.3%
74	Bacterial Endocarditis	15.1%
75	Impetigo	15%
76	Actinomycosis	14.8%
77	Corynebacterium Infections	14.8%
78	Gas Gangrene	14.8%
79	Mycobacterium Infections	14.8%
80	Nocardia Infections	14.8%
81	Pneumococcal Infections	14.8%
82	Scarlet Fever	14.8%
83	Tetanus	14.8%
84	Pulmonary Nocardiosis	14.8%
85	Erythrasma	14.7%
86	Erysipelothrix infection	14.3%
87	Rhinoscleroma	13.7%
88	Ophthalmia Neonatorum	13.6%
89	Trachoma	13.6%
90	Ecthyma	13.1%
91	Subacute Bacterial Endocarditis	13.1%
92	Staphylococcal Scalded Skin Syndrome	12.2%
93	Central Nervous System Infection	12.2%
94	Diphtheria	12.2%
95	Leprosy	12.2%
96	Mycobacterium Infections, Nontuberculous	12.2%
97	Tuberculosis	12.2%
98	Mycobacterium abscessus Infection	12.2%
99	Mycetoma	12%
100	Meningitis, Listeria	11.7%
101	Mycobacterium avium-intracellulare Infection	10.9%
102	Lymph Node Tuberculosis	10.9%
103	Tuberculosis, Miliary	10.9%
104	Tuberculosis, Multidrug-Resistant	10.9%
105	Leprosy, Multibacillary	10.9%
106	Latent Tuberculosis	10.9%
107	Meningitis, Pneumococcal	10.6%
108	carbuncle	10.5%
109	Hidradenitis Suppurativa	10.4%
110	Furunculosis	10.4%
111	furuncle	10.4%
112	Aspergillosis	10.3%
113	Candidiasis	10.3%
114	Coccidioidomycosis	10.3%
115	Histoplasmosis	10.3%
116	Paracoccidioidomycosis	10.3%
117	Pelvic Infection	10.3%
118	Wound Infection	10.3%
119	Zygomycosis	10.3%
120	Soft Tissue Infection	10.3%
121	Community-Acquired Infections	10.3%
122	Phaeohyphomycosis	10.3%
123	Pneumocystis Infections	10.3%
124	Borderline leprosy	10.3%
125	Leprosy, Lepromatous	10.3%
126	Tuberculoid leprosy	10.3%
127	Extensively Drug-Resistant Tuberculosis	10.3%
128	Hordeolum	10.1%
129	Bacterial conjunctivitis	9.9%
130	Meningitis, Bacterial	9.9%
131	Joint Tuberculosis	8.8%
132	Tuberculosis, Osteoarticular	8.8%
133	Bone Tuberculosis	8.8%
134	Dermatomycoses	8.5%
135	Rheumatic Heart Disease	8.4%
136	Lemierre Syndrome	8.2%
137	Tuberculosis, Meningeal	8.2%
138	Rheumatic Fever	7.6%
139	Tuberculosis, Gastrointestinal	7.5%
140	Waterhouse-Friderichsen Syndrome	7.5%
141	Enterocolitis, Pseudomembranous	7.3%
142	Eye Infection	7.3%
143	Respiratory Tract Infections	7.3%
144	pseudomembranous colitis	7.3%
145	Tuberculosis, Central Nervous System	7.3%
146	Erythema Induratum	7.3%
147	Candidiasis, Chronic Mucocutaneous	7.2%
148	Cutaneous Candidiasis	7.2%
149	Bone Diseases, Infectious	7%
150	Otomycosis	7%
151	Pregnancy Complications, Infectious	7%
152	Skin Diseases, Infectious	7%
153	Panophthalmitis	6.9%
154	Arthritis, Infectious	6.8%
155	Piedra	6.8%
156	Central Nervous System Fungal Infections	6.8%
157	Suppuration	6.8%
158	Cross Infection	6.7%
159	Septicemia	6.7%
160	Sepsis	6.7%
161	Mucormycosis	6.7%
162	Neuroaspergillosis	6.6%
163	Fungemia	6.6%
164	Candidemia	6.5%
165	Tuberculosis, Spinal	6.1%
166	Botulism	6%
167	Brain Abscess	6%
168	Chromoblastomycosis	5.7%
169	Dermatophytosis	5.7%
170	Sporotrichosis	5.7%
171	Tinea	5.7%
172	Tinea Versicolor	5.7%
173	Trichophytosis	5.7%
174	Invasive Pulmonary Aspergillosis	5.7%
175	Hyalohyphomycosis	5.7%
176	Tuberculosis, Pulmonary	5.7%
177	Endotoxemia	5.7%
178	Opportunistic Infections	5.7%
179	Cellulitis	5.4%
180	Lung Diseases, Fungal	5.3%
181	Blastomycosis	5.2%
182	Urinary tract infection	5.2%
183	Psoas Abscess	4.9%
184	Abdominal Abscess	4.9%
185	Meningitis, Cryptococcal	4.6%
186	Oral candidiasis	4.5%
187	Endophthalmitis	4.5%
188	Peritonitis	4.5%
189	Osteomyelitis	4.4%
190	Periostitis	4.4%
191	Surgical Wound Infection	4.4%
192	Pulmonary Aspergillosis	4.4%
193	Bronchopulmonary Aspergillosis	4.4%
194	Fusariosis	4.4%
195	Abscess	4.4%
196	Adnexitis	4.4%
197	Empyema	4.4%
198	Pelvic Inflammatory Disease	4.4%
199	Sexually Transmitted Diseases	4.3%
200	Tinea Capitis	3.6%
201	Onychomycosis	3.6%
202	Tuberculosis, Renal	3.5%
203	Superinfection	3.4%
204	Corneal Ulcer	3.4%
205	Puerperal Infection	3.3%
206	Spondylitis	3.3%
207	Appendicitis	3.3%
208	Bacteriuria	3.3%
209	Pyuria	3.3%
210	Meningitis, Fungal	3.3%
211	Pyomyositis	3.3%
212	Endotoxic shock	3.3%
213	Septic Shock	3.3%
214	Toxic Shock Syndrome	3.3%
215	Diverticulitis	3.3%
216	Candidiasis, Vulvovaginal	3.2%
217	Tinea Pedis	3%
218	Liver Abscess	2.8%
219	Toxoplasmosis, Cerebral	2.6%
220	Arthritis, Reactive	2.6%
221	Lung Abscess	2.6%
222	Diverticulum	2.5%
223	Diverticulosis	2.5%
224	Discitis	2.4%
225	Mastoiditis	2.4%
226	Petrositis	2.4%
227	AIDS-Related Opportunistic Infections	2.3%
228	Retropharyngeal Abscess	2%
229	Epidural Abscess	2%
230	Peritonsillar Abscess	1.9%
231	Aspergillosis, Allergic Bronchopulmonary	1.7%
232	Liver Abscess, Amebic	1.3%

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