MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Substance Dependence

(UMLS:C0038580)

UMLS ID:: C0038580
MeSH ID:: D019966

Classification 1:

Name:

Chemically-Induced Disorders
MeSH Tree Number(s):: C25.775

Classification 2:

Name:

Mental Disorders
MeSH Tree Number(s):: F03.900

Synonym(s)

Substance Dependence

SUBSTANCE DEPENDENCE

Substance dependence

Substance dependence, NOS

addiction chemical

addictions substance

chemical addiction

chemical dependence

chemical dependencies

10.

chemical dependency

11.

dependence substance

12.

dependence substances

13.

substance addiction

14.

substance dependence

15.

substance; dependence

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Aripiprazole	FAERS: 7	US FAERS
2	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 2	US FAERS
3	Naltrexone	FAERS: 2	US FAERS
4	Buprenorphine	FAERS: 1	US FAERS
5	Cabergoline	FAERS: 1	US FAERS
6	Hydromorphone	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
7	Nitrous Oxide	FAERS: 1	US FAERS
8	Clozapine	Canada Vigilance: 1	Canada Vigilance
9	Morphine	Canada Vigilance: 1	Canada Vigilance

Similar ADE(s)

	Name	Semantic Similarity
1	Neurotic Disorders	28%
2	Separation Anxiety Disorder	23.1%
3	Anxiety Disorders	22.2%
4	Avoidant Personality Disorder	22.2%
5	Dissociative disorder	22.2%
6	Drug toxicity	22.2%
7	Frigidity	22.2%
8	Hypoactive Sexual Desire Disorder	22.2%
9	Disruptive, Impulse Control, and Conduct Disorders	22.2%
10	Intermittent Explosive Disorder	22.2%
11	Kleptomania	22.2%
12	Narcissistic Personality Disorder	22.2%
13	Personality Disorders	22.2%
14	Poisoning	22.2%
15	Sexual Aversion Disorder	22.2%
16	Somatoform Disorder	22.2%
17	Dissociation	22.2%
18	Motor Disorders	22.2%
19	Mood Disorders	22.2%
20	Schizophrenia Spectrum and Other Psychotic Disorders	22.2%
21	Neurodevelopmental Disorders	22.2%
22	Neurocognitive Disorders	22.2%
23	Feeding and Eating Disorders	22.2%
24	Mushroom Poisoning	18.5%
25	Chemical and Drug Induced Liver Injury	18.2%
26	Adjustment Disorders	15.8%
27	Affective Disorders, Psychotic	15.8%
28	Agoraphobia	15.8%
29	Anorexia Nervosa	15.8%
30	Antisocial Personality Disorder	15.8%
31	Bipolar Disorder	15.8%
32	Body Dysmorphic Disorders	15.8%
33	Borderline Personality Disorder	15.8%
34	Capgras Syndrome	15.8%
35	Child Behavior Disorders	15.8%
36	Developmental Disabilities	15.8%
37	Child Development Disorders, Pervasive	15.8%
38	Claustrophobia	15.8%
39	Cognition Disorders	15.8%
40	Conversion disorder	15.8%
41	Cyclothymic Disorder	15.8%
42	Dependent Personality Disorder	15.8%
43	Depressive disorder	15.8%
44	Developmental Coordination Disorder	15.8%
45	Exhibitionism	15.8%
46	Factitious Disorders	15.8%
47	Firesetting Behavior	15.8%
48	Fluoride Poisoning	15.8%
49	Food Poisoning	15.8%
50	Gas Poisoning	15.8%
51	Head Banging	15.8%
52	Histrionic Personality Disorder	15.8%
53	Hypochondriasis	15.8%
54	Masochism	15.8%
55	Melancholia	15.8%
56	Motor Skills Disorders	15.8%
57	Dissociative Identity Disorder	15.8%
58	Mycotoxicosis	15.8%
59	Neurasthenia	15.8%
60	Obsessive-Compulsive Disorder	15.8%
61	Oppositional Defiant Disorder	15.8%
62	Panic Disorder	15.8%
63	Paranoid Personality Disorder	15.8%
64	Pedophilia	15.8%
65	Plant Poisoning	15.8%
66	Pseudodementia	15.8%
67	Psychotic Disorders	15.8%
68	Sadism	15.8%
69	Schizoaffective Disorder	15.8%
70	Schizoid Personality Disorder	15.8%
71	Schizophrenia	15.8%
72	Schizophrenia, Childhood	15.8%
73	Schizotypal Personality Disorder	15.8%
74	Stereotypic Movement Disorder	15.8%
75	Transvestism	15.8%
76	Trichotillomania	15.8%
77	Voyeurism	15.8%
78	Anticholinergic Syndrome	15.8%
79	Attention Deficit and Disruptive Behavior Disorders	15.8%
80	Hyperkinetic Heart Syndrome	15.8%
81	Reactive Attachment Disorder	15.8%
82	Sexual and Gender Disorders	15.8%
83	Gender Dysphoria	15.8%
84	Serotonin Syndrome	15.8%
85	Organophosphate poisoning	15.8%
86	Propofol Infusion Syndrome	15.8%
87	Paranoia	15.8%
88	Compulsive Personality Disorder	15.8%
89	Bulimia Nervosa	15.8%
90	Chemical and Drug Induced Liver Injury, Chronic	14.5%
91	Psychoses, Substance-Induced	13.6%
92	Cadmium poisoning	12.8%
93	Carbon Monoxide Poisoning	12.8%
94	Ciguatera Poisoning	12.8%
95	Combat Disorders	12.8%
96	Dysthymic Disorder	12.8%
97	Ergotism	12.8%
98	Hysteria	12.8%
99	Lead Poisoning	12.8%
100	Mercury Poisoning	12.8%
101	Schizophrenia, Catatonic	12.8%
102	Schizophrenia, Disorganized	12.8%
103	Post-Traumatic Stress Disorder	12.8%
104	Attention Deficit Disorder	12.8%
105	Seasonal Affective Disorder	12.8%
106	Conduct Disorder	12.8%
107	Social Communication Disorder	12.8%
108	Shellfish Poisoning	12.8%
109	Psychological Trauma	12.8%
110	Hoarding Disorder	12.8%
111	Phonological Disorder	12.8%
112	Sleep Wake Disorders	12.7%
113	Bites and Stings	12%
114	Neurotoxicity Syndromes	12%
115	Parasomnia	11.5%
116	Dyssomnias	11.5%
117	Metabolic Side Effects of Drugs and Substances	11.5%
118	Autistic Disorder	11.4%
119	Asperger Syndrome	11.4%
120	Gambling	11.3%
121	Premature Ejaculation	11.3%
122	Water Intoxication	11.3%
123	Injection Site Reaction	11.3%
124	Erectile dysfunction	11.3%
125	Arsenic Poisoning	11.3%
126	Dementia	11.3%
127	Infusion site reaction	11.3%
128	Akathisia, Drug-Induced	11.3%
129	Psychoses, Alcoholic	11.2%
130	Tick Paralysis	10.7%
131	Restless Legs Syndrome	9.8%
132	Dyskinesia, Drug-Induced	9.7%
133	Insect Bites and Stings	9.4%
134	Argyria	9.3%
135	Depression, Postpartum	9.3%
136	Sleep Talking	9.3%
137	Manganese Poisoning	9.3%
138	Sleep Disorders, Intrinsic	9.3%
139	Kluver-Bucy Syndrome	9.2%
140	Premenstrual Dysphoric Disorder	9.2%
141	Salmonella food poisoning	9.1%
142	Dyspareunia	8.8%
143	Mutism	8.6%
144	Selective Mutism	8.6%
145	Mercury Poisoning, Nervous System	8.3%
146	Lead Poisoning, Nervous System	8.3%
147	Disorders of Excessive Somnolence	8.2%
148	Sleep Initiation and Maintenance Disorders	8.2%
149	Night Terrors	8.2%
150	Somnambulism	8.2%
151	Transient Insomnia	8.2%
152	Sleep Paralysis	8.2%
153	Chronic Insomnia	8.2%
154	REM Sleep Behavior Disorder	8.2%
155	Hypersomnia	8.2%
156	Lead Poisoning, Nervous System, Childhood	7.7%
157	Lead Poisoning, Nervous System, Adult	7.7%
158	Narcolepsy	7.7%
159	Kleine-Levin Syndrome	7.7%
160	Huntington Disease	7.6%
161	Pick Disease of the Brain	7.6%
162	Cataplexy	7.4%
163	Cardiotoxicity	7.4%
164	Neuroleptic Malignant Syndrome	7.3%
165	Alcohol-Induced Disorders, Nervous System	7.3%
166	Consciousness Disorders	7.3%
167	Mental Retardation	7.3%
168	Depressed Level of Consciousness	7.3%
169	Mental deficiency	7.3%
170	Intellectual Disability	7.3%
171	Drug Eruptions	7.2%
172	Sleep Bruxism	7.2%
173	Presenile dementia	7.2%
174	Senile dementia	7.2%
175	Enuresis	7.2%
176	Creutzfeldt-Jakob disease	7.1%
177	Amnesia	7.1%
178	Delirium	7.1%
179	Dissociative Amnesia	7.1%
180	Global Amnesia	7.1%
181	Dyscalculia	7.1%
182	Alexia, Pure	7.1%
183	Acute Generalized Exanthematous Pustulosis	6.4%
184	Sleep Disorders, Circadian Rhythm	6.2%
185	Acrodynia	6%
186	Botulism	6%
187	Sleep Deprivation	5.9%
188	MPTP Poisoning	5.9%
189	Diurnal Enuresis	5.8%
190	Retrograde amnesia	5.8%
191	Amnesia, Anterograde	5.8%
192	Erythema Nodosum	5.3%
193	Serum Sickness	5.3%
194	Frontotemporal dementia	5.2%
195	Asthma, Aspirin-Induced	5.1%
196	Lewy Body Disease	5%
197	AIDS Dementia Complex	5%
198	Amnesia, Transient Global	4.9%
199	Alexia	4.9%
200	Dyslexia	4.9%
201	Jet Lag Syndrome	4.5%
202	Auditory Perceptual Disorders	4.3%
203	Alcohol Withdrawal Delirium	3.9%
204	Alcohol Withdrawal Seizures	3.9%
205	Toxic Epidermal Necrolysis	3.9%
206	Stevens-Johnson Syndrome	3.9%
207	Dementia, Vascular	3.8%

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