MetaADEDB 2.0 @ LMMD
Meclizine
(OCJYIGYOJCODJL-UHFFFAOYSA-N)
Structure
SMILES
Clc1ccc(cc1)C(c1ccccc1)N1CCN(CC1)Cc1cccc(c1)C
Type(s)
Approved
ATC code(s)
R06AE05; R06AE55
Molecular Formula:
C25H27ClN2
Molecular Weight:
390.948
Log P:
5.4314
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
6.48
CAS Number(s):
569-65-3; 189298-48-4
Synonym(s)
1.
Meclizine
External Link(s)
PubChem Compound4034
BindingDB81467
ChEBI6709
CHEMBLCHEMBL1623
DrugBankDB00737
DrugCentral1649
IUPHAR/BPS Guide to PHARMACOLOGY2757
KEGGcpd:C07116
dr:D08163
Therapeutic Target DatabaseD0T1XW
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 15US FAERS
2DizzinessFAERS: 128351028CTD
OFFSIDES
US FAERS
3SomnolenceFAERS: 7SIDER
US FAERS
4Drug exposure during pregnancyFAERS: 6US FAERS
5Feeling abnormalFAERS: 5US FAERS
6VertigoFAERS: 43515563CTD
US FAERS
7AstheniaFAERS: 3OFFSIDES
SIDER
US FAERS
8HeadacheFAERS: 3SIDER
US FAERS
9MalaiseFAERS: 3US FAERS
10Accidental drug intake by childFAERS: 2US FAERS
11AmnesiaFAERS: 2OFFSIDES
US FAERS
12Chest discomfortFAERS: 2US FAERS
13Euphoric moodFAERS: 2US FAERS
14HypersensitivityFAERS: 2US FAERS
15Incorrect dose administeredFAERS: 2US FAERS
16NauseaFAERS: 219890085CTD
OFFSIDES
US FAERS
17OverdoseFAERS: 2OFFSIDES
US FAERS
18Pharmaceutical product complaintFAERS: 2US FAERS
19Product substitution issueFAERS: 2US FAERS
20Therapeutic response unexpectedFAERS: 2US FAERS
21Angle Closure GlaucomaFAERS: 1US FAERS
22ArthropathyFAERS: 1US FAERS
23AsthmaFAERS: 1OFFSIDES
US FAERS
24Atrial FibrillationFAERS: 1US FAERS
25BradyphreniaFAERS: 1US FAERS
26ConstipationFAERS: 1US FAERS
27Coronary Artery DiseaseFAERS: 1US FAERS
28DeafnessFAERS: 1US FAERS
29DiplopiaFAERS: 1US FAERS
30DiscomfortFAERS: 1US FAERS
31Drug dose omissionFAERS: 1US FAERS
32Drug prescribing errorFAERS: 1US FAERS
33DysarthriaFAERS: 1US FAERS
34DysgeusiaFAERS: 1OFFSIDES
US FAERS
35Ex-tobacco userFAERS: 1US FAERS
36Expired drug administeredFAERS: 1US FAERS
37Expired product administeredFAERS: 1US FAERS
38Eye irritationFAERS: 1US FAERS
39Eye painFAERS: 1US FAERS
40FatigueFAERS: 1OFFSIDES
SIDER
US FAERS
41Head titubationFAERS: 1US FAERS
42HyperacusisFAERS: 1US FAERS
43HypersomniaFAERS: 1US FAERS
44HypospadiasFAERS: 1US FAERS
45Memory impairmentFAERS: 1US FAERS
46MyalgiaFAERS: 1US FAERS
47MydriasisFAERS: 1US FAERS
48MyopiaFAERS: 1US FAERS
49PallorFAERS: 1US FAERS
50PalpitationsFAERS: 1US FAERS
51Productive CoughFAERS: 1US FAERS
52PruritusFAERS: 1US FAERS
53StaringFAERS: 1US FAERS
54StrabismusFAERS: 1US FAERS
55TremorFAERS: 1US FAERS
56Tympanic Membrane PerforationFAERS: 1US FAERS
57Unresponsive to stimuliFAERS: 1OFFSIDES
US FAERS
58WheezingFAERS: 1US FAERS
59treatment failureFAERS: 1US FAERS
60AbasiaOFFSIDES
61Abdominal PainOFFSIDES
62Abdominal adhesionsOFFSIDES
63Abdominal discomfortOFFSIDES
64Abdominal sepsisOFFSIDES
65Acid refluxOFFSIDES
66Acute bronchitisOFFSIDES
67Acute myocardial infarctionOFFSIDES
68Acute respiratory failureOFFSIDES
69Adnexa uteri painOFFSIDES
70AgeusiaOFFSIDES
71AgraphiaOFFSIDES
72AlopeciaOFFSIDES
73AlveolitisOFFSIDES
74Anaphylactic shockSIDER
75Anaphylactoid ReactionSIDER
76AnhidrosisOFFSIDES
77Anticoagulation drug level above therapeuticOFFSIDES
78AnxietyOFFSIDES
79ApathyOFFSIDES
80Aphthous StomatitisOFFSIDES
81ArteriosclerosisOFFSIDES
82AtaxiaOFFSIDES
83AtherosclerosisOFFSIDES
84Basal Ganglia Diseases872535CTD
85Biopsy breast abnormalOFFSIDES
86Biopsy liver abnormalOFFSIDES
87BlepharoptosisOFFSIDES
88Blood 1,25-dihydroxycholecalciferol decreasedOFFSIDES
89Blood GlucoseOFFSIDES
90Blood albumin decreasedOFFSIDES
91Blood cholesterolOFFSIDES
92Blood glucose decreasedOFFSIDES
93Blood potassium decreasedOFFSIDES
94Blood triglycerides increasedOFFSIDES
95Blurred visionOFFSIDES
96BradycardiaOFFSIDES
97BronchitisOFFSIDES
98BruxismOFFSIDES
99CarcinomaOFFSIDES
100Cataract operationOFFSIDES
101CataractOFFSIDES
102CellulitisOFFSIDES
103Central nervous system lesionOFFSIDES
104Cerebral circulatory failureOFFSIDES
105Chest PainOFFSIDES
106Choking sensationOFFSIDES
107Chronic Fatigue SyndromeOFFSIDES
108Chronic Obstructive Airway DiseaseOFFSIDES
109ClaustrophobiaOFFSIDES
110Cognition Disorders15451046CTD
111ConfabulationOFFSIDES
112Confusion3571791CTD
113Congenital cystic kidney diseaseOFFSIDES
114Conjunctival abrasionOFFSIDES
115Coronary angioplastyOFFSIDES
116DehydrationOFFSIDES
117DemyelinationOFFSIDES
118DiabetesOFFSIDES
119Diabetes InsipidusOFFSIDES
120Diabetes mellitus inadequate controlOFFSIDES
121Diabetic NephropathyOFFSIDES
122Diabetic RetinopathyOFFSIDES
123DiarrheaOFFSIDES
124Diverticular perforationOFFSIDES
125DiverticulitisOFFSIDES
126DiverticulumOFFSIDES
127DrowsinessOFFSIDES
SIDER
128Drug resistanceOFFSIDES
129Drug withdrawal headacheOFFSIDES
130DyslexiaOFFSIDES
131DyspepsiaOFFSIDES
132DysphemiaOFFSIDES
133DysphoniaOFFSIDES
134Dyspnoea exacerbatedOFFSIDES
135DysuriaOFFSIDES
136Electromechanical dissociationOFFSIDES
137Emotional distressOFFSIDES
138EpicondylitisOFFSIDES
139Erectile dysfunctionOFFSIDES
140Esophageal StenosisOFFSIDES
141Essential TremorOFFSIDES
142ExcoriationOFFSIDES
143Eye laser surgeryOFFSIDES
144Eyelid DiseasesOFFSIDES
145Failure to ThriveOFFSIDES
146Feeling ColdOFFSIDES
147Food AllergyOFFSIDES
148Foreign body traumaOFFSIDES
149GamblingOFFSIDES
150Gastric ulcerOFFSIDES
151Gastrointestinal mucosal disorderOFFSIDES
152GlaucomaOFFSIDES
153GlobulinuriaOFFSIDES
154GoiterOFFSIDES
155GoutOFFSIDES
156Hallucinations15454584CTD
157HemiparesisOFFSIDES
158Immune reconstitution syndromeOFFSIDES
159Impaired driving abilityOFFSIDES
160IncontinenceOFFSIDES
161Increased upper airway secretionOFFSIDES
162InfectionOFFSIDES
163Injection site irritationOFFSIDES
164Intention tremorOFFSIDES
165Intervertebral Disc DegenerationOFFSIDES
166Intracranial AneurysmOFFSIDES
167Joint sprainOFFSIDES
168Kidney FailureOFFSIDES
169Leukopenia neonatalOFFSIDES
170LeukoplakiaOFFSIDES
171Ligament ruptureOFFSIDES
172LipaseOFFSIDES
173Livedo ReticularisOFFSIDES
174LymphedemaOFFSIDES
175MacrocytosisOFFSIDES
176MastectomyOFFSIDES
177Memory Disorders3571791CTD
178Mental status changesOFFSIDES
179Multiple SclerosisOFFSIDES
180Multiple drug overdose intentionalOFFSIDES
181Multiple sclerosis relapseOFFSIDES
182Musculoskeletal stiffnessOFFSIDES
183Nervous tensionOFFSIDES
184NocturiaOFFSIDES
185Non-cardiac chest painOFFSIDES
186Oropharyngeal swellingOFFSIDES
187OsteopeniaOFFSIDES
188PainOFFSIDES
189Partner stressOFFSIDES
190Pericardial effusionOFFSIDES
191PericarditisOFFSIDES
192Peripheral arterial occlusive diseaseOFFSIDES
193Peritoneal DialysisOFFSIDES
194PeritonitisOFFSIDES
195Pharyngolaryngeal PainOFFSIDES
196PolyuriaOFFSIDES
197PresbyopiaOFFSIDES
198Protein total abnormalOFFSIDES
199Pulmonary HypertensionOFFSIDES
200PyuriaOFFSIDES
201Quality of life decreasedOFFSIDES
202Residual urineOFFSIDES
203Respiratory FailureOFFSIDES
204Respiratory fume inhalation disorderOFFSIDES
205Retinal Artery OcclusionOFFSIDES
206Salivary gland operationOFFSIDES
207Scan lymph nodesOFFSIDES
208Schizoaffective DisorderOFFSIDES
209Septic ShockOFFSIDES
210Sigmoidoscopy abnormalOFFSIDES
211Skeletal injuryOFFSIDES
212Skin lacerationOFFSIDES
213Spinal claudicationOFFSIDES
214Spinal fusion surgeryOFFSIDES
215Stent occlusionOFFSIDES
216Substance Withdrawal Syndrome19890085CTD
217Supraventricular tachycardiaOFFSIDES
218Synovial CystOFFSIDES
219Temperature intoleranceOFFSIDES
220TendinitisOFFSIDES
221Therapeutic procedureOFFSIDES
222Tooth LossOFFSIDES
223Urine output increasedOFFSIDES
224Weight GainOFFSIDES
225furuncleOFFSIDES
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