Varenicline
(JQSHBVHOMNKWFT-UHFFFAOYSA-N)
Structure
- SMILES
- N1CC2CC(C1)c1c2cc2c(c1)nccn2
- Type(s)
- Approved; Investigational
- ATC code(s)
- N07BA03
- Molecular Formula:
- C13H13N3
- Molecular Weight:
- 211.262
- Log P:
- 2.1327
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 1
- TPSA:
- 37.81
- CAS Number(s):
- 249296-44-4
Synonym(s)
1.
Varenicline
2.
6,7,8,9-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)benzazepine
3.
Champix
4.
Chantix
5.
Varenicline Tartrate
External Link(s)
| MeSH | D000068580 |
| PubChem Compound | 170361 |
| BindingDB | 50166908 50174159 |
| CHEMBL | CHEMBL1396 |
| DrugBank | DB01273 |
| KEGG | dr:D08669 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Nausea | FAERS: 12 | US FAERS | |
| 2 | Headache | FAERS: 10 | US FAERS | |
| 3 | Anxiety | FAERS: 8 | US FAERS | |
| 4 | Mood swings | FAERS: 7 | US FAERS | |
| 5 | Anger | FAERS: 6 | US FAERS | |
| 6 | Palpitations | FAERS: 6 | US FAERS | |
| 7 | Asthenia | FAERS: 5 | US FAERS | |
| 8 | Fatigue | FAERS: 5 | US FAERS | |
| 9 | Paranoia | FAERS: 5 | US FAERS | |
| 10 | Vertigo | FAERS: 5 | US FAERS | |
| 11 | Vomiting | FAERS: 5 | US FAERS | |
| 12 | Depressed mood | FAERS: 4 | US FAERS | |
| 13 | Feeling abnormal | FAERS: 4 | US FAERS | |
| 14 | Alanine Aminotransferase Increased | FAERS: 3 | US FAERS | |
| 15 | Constipation | FAERS: 3 | US FAERS | |
| 16 | Crying | FAERS: 3 | US FAERS | |
| 17 | Lethargy | FAERS: 3 | US FAERS | |
| 18 | Malaise | FAERS: 3 | US FAERS | |
| 19 | Pain | FAERS: 3 | US FAERS | |
| 20 | Personality Change | FAERS: 3 | US FAERS | |
| 21 | Pharyngolaryngeal Pain | FAERS: 3 | US FAERS | |
| 22 | Tremor | FAERS: 3 | US FAERS | |
| 23 | Ventricular Fibrillation | FAERS: 3 | US FAERS | |
| 24 | Agitation | FAERS: 2 | US FAERS | |
| 25 | Anal discomfort | FAERS: 2 | US FAERS | |
| 26 | Anorexia | FAERS: 2 | US FAERS | |
| 27 | Bipolar Disorder | FAERS: 2 | US FAERS | |
| 28 | Bipolar I disorder | FAERS: 2 | US FAERS | |
| 29 | Chest Pain | FAERS: 2 | US FAERS | |
| 30 | Diplopia | FAERS: 2 | US FAERS | |
| 31 | Dizziness | FAERS: 2 | US FAERS | |
| 32 | Exaggerated startle response | FAERS: 2 | US FAERS | |
| 33 | Flatulence | FAERS: 2 | US FAERS | |
| 34 | Flight of ideas | FAERS: 2 | US FAERS | |
| 35 | Pharyngitis | FAERS: 2 | US FAERS | |
| 36 | Vulvovaginal discomfort | FAERS: 2 | US FAERS | |
| 37 | Weight decreased | FAERS: 2 | US FAERS | |
| 38 | Abasia | FAERS: 1 | US FAERS | |
| 39 | Alopecia | FAERS: 1 | US FAERS | |
| 40 | Amnesia | FAERS: 1 | US FAERS | |
| 41 | Aphasia | FAERS: 1 | US FAERS | |
| 42 | Arthralgia | FAERS: 1 | US FAERS | |
| 43 | Asthma | FAERS: 1 | US FAERS | |
| 44 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 45 | Bronchitis | FAERS: 1 | US FAERS | |
| 46 | Burning sensation | FAERS: 1 | US FAERS | |
| 47 | Cellulitis | FAERS: 1 | US FAERS | |
| 48 | Chest discomfort | FAERS: 1 | US FAERS | |
| 49 | Delusional disorder, persecutory type | FAERS: 1 | US FAERS | |
| 50 | Disorientation | FAERS: 1 | US FAERS | |
| 51 | Drug abuse | FAERS: 1 | US FAERS | |
| 52 | Drug ineffective | FAERS: 1 | US FAERS | |
| 53 | Drug screen positive | FAERS: 1 | US FAERS | |
| 54 | Drug withdrawal syndrome | FAERS: 1 | US FAERS | |
| 55 | Duodenal Ulcer | FAERS: 1 | US FAERS | |
| 56 | Dysuria | FAERS: 1 | US FAERS | |
| 57 | Feeling Cold | FAERS: 1 | US FAERS | |
| 58 | Gastrointestinal erosion | FAERS: 1 | US FAERS | |
| 59 | Gastrointestinal inflammation | FAERS: 1 | US FAERS | |
| 60 | Hemiplegia | FAERS: 1 | US FAERS | |
| 61 | Hostility | FAERS: 1 | US FAERS | |
| 62 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 63 | Hypomania | FAERS: 1 | US FAERS | |
| 64 | Hypothyroidism | FAERS: 1 | US FAERS | |
| 65 | Impaired driving ability | FAERS: 1 | US FAERS | |
| 66 | Impaired work ability | FAERS: 1 | US FAERS | |
| 67 | Inflammation | FAERS: 1 | US FAERS | |
| 68 | Iron deficiency | FAERS: 1 | US FAERS | |
| 69 | Leukopenia | FAERS: 1 | US FAERS | |
| 70 | Memory impairment | FAERS: 1 | US FAERS | |
| 71 | Mental impairment | FAERS: 1 | US FAERS | |
| 72 | Muscle tightness | FAERS: 1 | US FAERS | |
| 73 | Myalgia | FAERS: 1 | US FAERS | |
| 74 | Myocardial Infarction | FAERS: 1 | US FAERS | |
| 75 | Neuralgia | FAERS: 1 | US FAERS | |
| 76 | Obsessive thoughts | FAERS: 1 | US FAERS | |
| 77 | Obsessive-Compulsive Disorder | FAERS: 1 | US FAERS | |
| 78 | Overdose | FAERS: 1 | US FAERS | |
| 79 | Peptic Ulcer | FAERS: 1 | US FAERS | |
| 80 | Pharmaceutical product complaint | FAERS: 1 | US FAERS | |
| 81 | Poor quality sleep | FAERS: 1 | US FAERS | |
| 82 | Posturing | FAERS: 1 | US FAERS | |
| 83 | Pressure of speech | FAERS: 1 | US FAERS | |
| 84 | Pruritus | FAERS: 1 | US FAERS | |
| 85 | Renal pain | FAERS: 1 | US FAERS | |
| 86 | Schizophrenia | FAERS: 1 | US FAERS | |
| 87 | Scleritis | FAERS: 1 | US FAERS | |
| 88 | Skin laceration | FAERS: 1 | US FAERS | |
| 89 | Somnambulism | FAERS: 1 | US FAERS | |
| 90 | Sudden death | FAERS: 1 | US FAERS | |
| 91 | Suicide attempt | FAERS: 1 | US FAERS | |
| 92 | Suprapubic pain | FAERS: 1 | US FAERS | |
| 93 | Syncope | FAERS: 1 | US FAERS | |
| 94 | Troponin T increased | FAERS: 1 | US FAERS | |
| 95 | Unevaluable event | FAERS: 1 | US FAERS | |
| 96 | Violence-related symptom | FAERS: 1 | US FAERS | |
| 97 | Vulvovaginal pruritus | FAERS: 1 | US FAERS | |
| 98 | Wheezing | FAERS: 1 | US FAERS | |
| 99 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 100 | nervous system disorder | FAERS: 1 | US FAERS |
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