MetaADEDB 2.0 @ LMMD
frovatriptan
(XPSQPHWEGNHMSK-SECBINFHSA-N)
Structure
SMILES
CN[C@H]1Cc2c(CC1)[nH]c1c2cc(cc1)C(=O)N
Type(s)
Approved; Investigational
ATC code(s)
N02CC07
Molecular Formula:
C14H17N3O
Molecular Weight:
243.304
Log P:
2.4347
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
3
TPSA:
70.91
CAS Number(s):
158747-02-5
Synonym(s)
1.
frovatriptan
2.
(+)-(R)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide succinate (1:1), monohydrate
3.
3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole
4.
Allegro
5.
Frova
6.
Frovelan
7.
SB 209509
8.
VML-251
9.
VML251
10.
frovatriptan succinate
External Link(s)
MeSHC108128
PubChem Compound77992
BindingDB50073689
ChEBI134991
CHEMBLCHEMBL1279
DrugBankDB00998
DrugCentral1251
IUPHAR/BPS Guide to PHARMACOLOGY7191
KEGGdr:D07997
Therapeutic Target DatabaseD06FPQ
ZINC18635
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1HeadacheFAERS: 15SIDER
US FAERS
2Drug ineffectiveFAERS: 14US FAERS
3NauseaFAERS: 8OFFSIDES
SIDER
US FAERS
4DizzinessFAERS: 6
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
5VomitingFAERS: 6SIDER
US FAERS
6AnxietyFAERS: 2SIDER
US FAERS
7ArthralgiaFAERS: 2SIDER
US FAERS
8AstheniaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
9Drug DependenceFAERS: 2US FAERS
10Drug exposure during pregnancyFAERS: 2US FAERS
11Erythema NodosumFAERS: 2US FAERS
12FatigueFAERS: 2OFFSIDES
SIDER
US FAERS
13Intentional drug misuseFAERS: 2US FAERS
14NasopharyngitisFAERS: 2US FAERS
15OverdoseFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
16PainFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
17Product blister packaging issueFAERS: 2US FAERS
18Therapeutic response unexpectedFAERS: 2US FAERS
19Accidental drug intake by childFAERS: 1US FAERS
20Acute Coronary SyndromeFAERS: 119538745CTD
SIDER
US FAERS
21Acute myocardial infarctionFAERS: 1US FAERS
22Adverse eventFAERS: 1US FAERS
23Altered visual depth perceptionFAERS: 1US FAERS
24AmnesiaFAERS: 1SIDER
US FAERS
25AngioedemaFAERS: 1OFFSIDES
US FAERS
26Angle Closure GlaucomaFAERS: 1US FAERS
27AphasiaFAERS: 1US FAERS
28Blood cholesterol increasedFAERS: 1US FAERS
29Cardiac ArrestFAERS: 1US FAERS
30Cerebral InfarctionFAERS: 1US FAERS
31Cerebrovascular accidentFAERS: 1US FAERS
32Cervical vertebra injuryFAERS: 1US FAERS
33Chest PainFAERS: 1SIDER
US FAERS
34Coronary Artery DiseaseFAERS: 1US FAERS
35CyanosisFAERS: 1US FAERS
36Drug effect delayedFAERS: 1US FAERS
37DyspepsiaFAERS: 1OFFSIDES
SIDER
US FAERS
38DystoniaFAERS: 1US FAERS
39EpilepsyFAERS: 1US FAERS
40Expired product administeredFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
41Exposure during breast feedingFAERS: 1US FAERS
42Eye painFAERS: 1SIDER
US FAERS
43Feeling ColdFAERS: 1SIDER
US FAERS
44Feeling abnormalFAERS: 1SIDER
US FAERS
45Food AllergyFAERS: 1US FAERS
46Gait inabilityFAERS: 1US FAERS
47HypokinesiaFAERS: 1US FAERS
48Infectious MononucleosisFAERS: 1US FAERS
49InflammationFAERS: 1US FAERS
50MalaiseFAERS: 1SIDER
US FAERS
51Maternal exposure during pregnancyFAERS: 1US FAERS
52Multiple SclerosisFAERS: 1OFFSIDES
US FAERS
53Muscle FatigueFAERS: 1US FAERS
54Myocardial InfarctionFAERS: 1SIDER
US FAERS
55Nasal pruritusFAERS: 1US FAERS
56Oropharyngeal painFAERS: 1US FAERS
57PalpitationsFAERS: 1SIDER
US FAERS
58PneumoniaFAERS: 1US FAERS
59Reaction to drug excipientsFAERS: 1US FAERS
60Serum serotonin decreasedFAERS: 1US FAERS
61SpondylosisFAERS: 1US FAERS
62StressFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
63SyncopeFAERS: 1SIDER
US FAERS
64ToothacheFAERS: 1SIDER
US FAERS
65Transaminases increasedFAERS: 1US FAERS
66Unevaluable eventFAERS: 1US FAERS
67Unexpected therapeutic drug effectFAERS: 1US FAERS
68Vascular ruptureFAERS: 1US FAERS
69Ventricular FibrillationFAERS: 1SIDER
US FAERS
70VertigoFAERS: 1SIDER
US FAERS
71Visual ImpairmentFAERS: 1SIDER
US FAERS
72Wrong technique in product usage processFAERS: 1US FAERS
73Abdominal PainSIDER
74Abnormal visionSIDER
75Acute bronchitisOFFSIDES
76AgitationSIDER
77Altered bowel functionOFFSIDES
78Amniotic fluid volume decreasedOFFSIDES
79Anaphylactic shockSIDER
80AnorexiaSIDER
81ArthropathySIDER
82AtaxiaSIDER
83Back PainSIDER
84Band neutrophil percentage increasedOFFSIDES
85Blood GlucoseOFFSIDES
86Blood pH decreasedOFFSIDES
87Blood sodiumOFFSIDES
88Blurred visionOFFSIDES
89Bone painOFFSIDES
SIDER
90BradycardiaSIDER
91Bullous eruptionSIDER
92Burning sensationOFFSIDES
93CheilitisSIDER
94Chest discomfortSIDER
95Chest tightnessSIDER
96ChillsSIDER
97ConjunctivitisSIDER
98ConstipationSIDER
99Cramps of lower extremitiesSIDER
100DehydrationSIDER
101Dependent Personality DisorderOFFSIDES
102Depression aggravatedSIDER
103DiabetesOFFSIDES
104DiscomfortSIDER
105Drug withdrawal headacheOFFSIDES
106DysgeusiaSIDER
107Electrocardiogram ST-T changeOFFSIDES
108Electrocardiogram abnormalSIDER
109EpistaxisSIDER
110EructationSIDER
111Euphoric moodSIDER
112Factor V deficiencyOFFSIDES
113FibromyalgiaOFFSIDES
114FlatulenceSIDER
115Fluid overloadOFFSIDES
116FlushingSIDER
117FolliculitisOFFSIDES
118FormicationOFFSIDES
119Gastrointestinal PainSIDER
120GoutOFFSIDES
121HyperacusisSIDER
122HypersensitivitySIDER
123HyperventilationSIDER
124Impaired driving abilityOFFSIDES
125Impaired gastric emptyingOFFSIDES
126Intention tremorOFFSIDES
127Lacrimation abnormal NOSSIDER
128LaryngitisSIDER
129Lymphocyte percentage decreasedOFFSIDES
130MalnutritionSIDER
131Medication overuse headacheSIDER
132Migraine Disorders15383196CTD
133Migraine aggravatedSIDER
134Migraine with Aura12028324CTD
135Mood swingsSIDER
136Muscle WeaknessOFFSIDES
137Muscle relaxant therapySIDER
138Musculoskeletal PainOFFSIDES
139Musculoskeletal discomfortSIDER
140Musculoskeletal stiffnessOFFSIDES
141MyalgiaCanada Vigilance: 1Canada Vigilance
SIDER
142Neonatal aspirationOFFSIDES
143NervousnessSIDER
144NeuromaOFFSIDES
145NocturiaSIDER
146Non-cardiac chest painOFFSIDES
147NumbnessSIDER
148OligomenorrheaOFFSIDES
149PCO2 increasedOFFSIDES
150Patellofemoral Pain SyndromeOFFSIDES
151Peptic UlcerSIDER
152PeriarthritisOFFSIDES
153PharyngitisSIDER
154PolyuriaSIDER
155Product counterfeitOFFSIDES
156PruritusSIDER
157PurpuraSIDER
158Renal painSIDER
159Retrograde amnesiaOFFSIDES
160RhinitisOFFSIDES
SIDER
161Salivary gland painSIDER
162Serotonin SyndromeSIDER
163ShockSIDER
164SinusitisSIDER
165SomnolenceSIDER
166Status MigrainosusOFFSIDES
167StomatitisSIDER
168TachycardiaSIDER
169Tardive DyskinesiaOFFSIDES
170TensionSIDER
171ThirstSIDER
172TinnitusSIDER
173TremorSIDER
174Urine output increasedSIDER
175Uterine PolypOFFSIDES
176Vascular purpuraSIDER
177VasospasmSIDER
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