MetaADEDB 2.0 @ LMMD
Prasugrel Hydrochloride
(DTGLZDAWLRGWQN-UHFFFAOYSA-N)
Structure
SMILES
CC(=O)Oc1sc2c(c1)CN(CC2)C(c1ccccc1F)C(=O)C1CC1
Type(s)
Approved
ATC code(s)
B01AC22
Molecular Formula:
C20H20FNO3S
Molecular Weight:
373.441
Log P:
3.8289
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
0
TPSA:
74.85
CAS Number(s):
150322-43-3
Synonym(s)
1.
Prasugrel Hydrochloride
2.
CS 747
3.
CS-747
4.
Effient
5.
Efient
6.
LY 640315
7.
LY-640315
8.
LY640315
9.
Prasugrel
10.
Prasugrel HCl
11.
640315, LY
12.
747, CS
13.
CS747
14.
HCl, Prasugrel
15.
Hydrochloride, Prasugrel
External Link(s)
MeSHD000068799
PubChem Compound6918456
ChEBI87723
CHEMBLCHEMBL1201772
DrugBankDB06209
DrugCentral4113
IUPHAR/BPS Guide to PHARMACOLOGY7562
KEGGdr:D05597
Therapeutic Target DatabaseD07IRF
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Thrombosis in deviceFAERS: 140US FAERS
2Myocardial InfarctionFAERS: 93
Canada Vigilance: 1
Canada Vigilance
US FAERS
3Chest PainFAERS: 83
Canada Vigilance: 1
Canada Vigilance
US FAERS
4Cerebrovascular accidentFAERS: 62
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
5Drug dose omissionFAERS: 61US FAERS
6Acute myocardial infarctionFAERS: 53US FAERS
7EpistaxisFAERS: 51SIDER
US FAERS
8FatigueFAERS: 51
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
9HeadacheFAERS: 49SIDER
US FAERS
10DizzinessFAERS: 45SIDER
US FAERS
11AstheniaFAERS: 35SIDER
US FAERS
12NauseaFAERS: 35SIDER
US FAERS
13Device occlusionFAERS: 31US FAERS
14MalaiseFAERS: 30US FAERS
15PruritusFAERS: 29US FAERS
16In-stent coronary artery restenosisFAERS: 28US FAERS
17Angina PectorisFAERS: 27
Canada Vigilance: 1
Canada Vigilance
US FAERS
18VomitingFAERS: 27US FAERS
19UrticariaFAERS: 26US FAERS
20ThrombosisFAERS: 25
Canada Vigilance: 1
Canada Vigilance
US FAERS
21Drug ineffectiveFAERS: 23US FAERS
22Feeling abnormalFAERS: 23US FAERS
23HypersensitivityFAERS: 21
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
24PainFAERS: 20US FAERS
25Abdominal PainFAERS: 19US FAERS
26Back PainFAERS: 18
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
27Vascular stent thrombosisFAERS: 18
Canada Vigilance: 2
Canada Vigilance
US FAERS
28Chest discomfortFAERS: 16US FAERS
29Coronary Artery DiseaseFAERS: 16
Canada Vigilance: 1
Canada Vigilance
US FAERS
30Cardiac ArrestFAERS: 14US FAERS
31OverdoseFAERS: 14US FAERS
32ThrombocytopeniaFAERS: 14SIDER
US FAERS
33AnxietyFAERS: 13US FAERS
34Deep Vein ThrombosisFAERS: 13US FAERS
35Drug dispensing errorFAERS: 13US FAERS
36PetechiaeFAERS: 13US FAERS
37Abdominal discomfortFAERS: 12US FAERS
38Atrial FibrillationFAERS: 12SIDER
US FAERS
39Visual ImpairmentFAERS: 12US FAERS
40ArthralgiaFAERS: 11US FAERS
41SwellingFAERS: 11US FAERS
42SyncopeFAERS: 11US FAERS
43DyspepsiaFAERS: 10
Canada Vigilance: 1
Canada Vigilance
US FAERS
44Intentional product misuseFAERS: 10US FAERS
45Medication ErrorFAERS: 10US FAERS
46PalpitationsFAERS: 10US FAERS
47Peripheral swellingFAERS: 10US FAERS
48Platelet function test abnormalFAERS: 10US FAERS
49Acute Coronary SyndromeFAERS: 9US FAERS
50AngioedemaFAERS: 9SIDER
US FAERS
51Blood urine presentFAERS: 9
Canada Vigilance: 1
Canada Vigilance
US FAERS
52ConstipationFAERS: 9US FAERS
53DysgeusiaFAERS: 9US FAERS
54HypotensionFAERS: 9SIDER
US FAERS
55Incorrect product storageFAERS: 9US FAERS
56MyalgiaFAERS: 9US FAERS
57No adverse eventFAERS: 9US FAERS
58PneumoniaFAERS: 9US FAERS
59SepsisFAERS: 9US FAERS
60ErythemaFAERS: 8US FAERS
61Gastric ulcerFAERS: 8US FAERS
62Non-cardiac chest painFAERS: 8SIDER
US FAERS
63Pericardial effusionFAERS: 8SIDER
US FAERS
64Vascular occlusionFAERS: 8US FAERS
65Weight decreasedFAERS: 8US FAERS
66Wrong technique in product usage processFAERS: 8US FAERS
67Accidental overdoseFAERS: 7US FAERS
68Alanine Aminotransferase IncreasedFAERS: 7US FAERS
69Arterial restenosisFAERS: 7US FAERS
70TinnitusFAERS: 7US FAERS
71Adverse eventFAERS: 6US FAERS
72AmnesiaFAERS: 6US FAERS
73DehydrationFAERS: 6US FAERS
74Diabetes MellitusFAERS: 6US FAERS
75DiverticulitisFAERS: 6US FAERS
76FlushingFAERS: 6US FAERS
77Gamma-Glutamyltransferase IncreasedFAERS: 6US FAERS
78In-stent arterial restenosisFAERS: 6US FAERS
79Joint swellingFAERS: 6US FAERS
80Prescribed overdoseFAERS: 6US FAERS
81Product counterfeitFAERS: 6US FAERS
82Troponin increasedFAERS: 6US FAERS
83Activities of daily living impairedFAERS: 5US FAERS
84AlopeciaFAERS: 5US FAERS
85AppendicitisFAERS: 5US FAERS
86ArteriosclerosisFAERS: 5US FAERS
87ArthritisFAERS: 5US FAERS
88Cardiac TamponadeFAERS: 5US FAERS
89ChromaturiaFAERS: 5US FAERS
90HerniaFAERS: 5US FAERS
91Intracranial AneurysmFAERS: 5US FAERS
92MenorrhagiaFAERS: 5US FAERS
93Neck PainFAERS: 5US FAERS
94Product storage errorFAERS: 5US FAERS
95AbasiaFAERS: 4US FAERS
96Arterial thrombosisFAERS: 4US FAERS
97Arteriovenous fistulaFAERS: 4US FAERS
98Aspartate Aminotransferase IncreasedFAERS: 4US FAERS
99BradycardiaFAERS: 4SIDER
US FAERS
100Cerebellar infarctionFAERS: 4US FAERS
101DiscomfortFAERS: 4US FAERS
102DisorientationFAERS: 4US FAERS
103EcchymosisFAERS: 4SIDER
US FAERS
104FlatulenceFAERS: 4US FAERS
105GastritisFAERS: 4US FAERS
106GastroenteritisFAERS: 4US FAERS
107HepatitisFAERS: 4US FAERS
108InfarctionFAERS: 4US FAERS
109InfluenzaFAERS: 4US FAERS
110Lip swellingFAERS: 4US FAERS
111Musculoskeletal PainFAERS: 4US FAERS
112Musculoskeletal stiffnessFAERS: 4US FAERS
113Oropharyngeal painFAERS: 4US FAERS
114PallorFAERS: 4US FAERS
115PancreatitisFAERS: 4US FAERS
116Percutaneous Coronary InterventionFAERS: 4US FAERS
117Platelet aggregation abnormalFAERS: 4US FAERS
118Post procedural complicationFAERS: 4US FAERS
119PurpuraFAERS: 4US FAERS
120Respiratory distressFAERS: 4US FAERS
121ShockFAERS: 4US FAERS
122Stent embolisationFAERS: 4US FAERS
123Sudden deathFAERS: 4US FAERS
124treatment failureFAERS: 4US FAERS
125AgitationFAERS: 3US FAERS
126AphasiaFAERS: 3US FAERS
127Blood count abnormalFAERS: 3US FAERS
128Blood glucose increasedFAERS: 3US FAERS
129Carotid artery occlusionFAERS: 3US FAERS
130ChillsFAERS: 3US FAERS
131CholelithiasisFAERS: 3US FAERS
132Drug resistanceFAERS: 3US FAERS
133DysarthriaFAERS: 3US FAERS
134Gastrointestinal PainFAERS: 3US FAERS
135GoutFAERS: 3US FAERS
136HemiplegiaFAERS: 3US FAERS
137Incorrect dose administeredFAERS: 3US FAERS
138Increased tendency to bruiseFAERS: 3US FAERS
139LacerationFAERS: 3US FAERS
140NasopharyngitisFAERS: 3US FAERS
141PancytopeniaFAERS: 3US FAERS
142PhotophobiaFAERS: 3US FAERS
143PresyncopeFAERS: 3US FAERS
144Product substitution issueFAERS: 3US FAERS
145Respiratory FailureFAERS: 3US FAERS
146Sudden Cardiac DeathFAERS: 3US FAERS
147Thermal burnFAERS: 3US FAERS
148ThrombocytosisFAERS: 3US FAERS
149TremorFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
150UlcerFAERS: 3US FAERS
151nervous system disorderFAERS: 3US FAERS
152Aortic AneurysmFAERS: 2US FAERS
153ArthropathyFAERS: 2US FAERS
154Atrial thrombosisFAERS: 2US FAERS
155Atrioventricular BlockFAERS: 2US FAERS
156BlindnessFAERS: 2US FAERS
157CataractFAERS: 2US FAERS
158Cerebral InfarctionFAERS: 2US FAERS
159ColectomyFAERS: 2US FAERS
160DeafnessFAERS: 2US FAERS
161Depressed moodFAERS: 2US FAERS
162DiplopiaFAERS: 2US FAERS
163Disease ProgressionFAERS: 2US FAERS
164Drug administration errorFAERS: 2US FAERS
165Drug prescribing errorFAERS: 2US FAERS
166Dry skinFAERS: 2US FAERS
167Ejection Fraction DecreasedFAERS: 2US FAERS
168Embolic strokeFAERS: 2US FAERS
169Erectile dysfunctionFAERS: 2US FAERS
170General physical health deteriorationFAERS: 2US FAERS
171Guillain-Barre SyndromeFAERS: 2US FAERS
172Implantable defibrillator insertionFAERS: 2US FAERS
173Incorrect storage of drugFAERS: 2US FAERS
174InfectionFAERS: 2US FAERS
175InflammationFAERS: 2US FAERS
176Intentional drug misuseFAERS: 2US FAERS
177Intercepted drug dispensing errorFAERS: 2US FAERS
178Joint injuryFAERS: 2US FAERS
179LethargyFAERS: 2US FAERS
180Limb injuryFAERS: 2US FAERS
181Livedo ReticularisFAERS: 2US FAERS
182Maternal exposure during pregnancyFAERS: 2US FAERS
183Memory impairmentFAERS: 2US FAERS
184Metastatic NeoplasmFAERS: 2US FAERS
185NephrolithiasisFAERS: 2US FAERS
186Peptic UlcerFAERS: 2US FAERS
187PericarditisFAERS: 2US FAERS
188Peripheral arterial occlusive diseaseFAERS: 2US FAERS
189Platelet aggregation decreasedFAERS: 2US FAERS
190Platelet count abnormalFAERS: 2US FAERS
191Post procedural infectionFAERS: 2US FAERS
192Procedural complicationFAERS: 2US FAERS
193Product dispensing errorFAERS: 2US FAERS
194Product quality issueFAERS: 2US FAERS
195SneezingFAERS: 2US FAERS
196SomnolenceFAERS: 2US FAERS
197Stent malfunctionFAERS: 2US FAERS
198StressFAERS: 2US FAERS
199ThrombophlebitisFAERS: 2US FAERS
200Tooth ExtractionFAERS: 2US FAERS
201ToothacheFAERS: 2US FAERS
202Troponin T increasedFAERS: 2US FAERS
203Unresponsive to stimuliFAERS: 2US FAERS
204Venous occlusionFAERS: 2US FAERS
205Ventricle ruptureFAERS: 2US FAERS
206Ventricular FibrillationFAERS: 2US FAERS
207VertigoFAERS: 2US FAERS
208White blood cell count decreasedFAERS: 2US FAERS
209jaundiceFAERS: 2US FAERS
210Abdominal InfectionFAERS: 1US FAERS
211AbscessFAERS: 1US FAERS
212AcneFAERS: 1US FAERS
213Activated partial thromboplastin time abnormalFAERS: 1US FAERS
214Acute kidney injuryFAERS: 1US FAERS
215Acute right ventricular failureFAERS: 1US FAERS
216AdenocarcinomaFAERS: 1US FAERS
217Adrenal massFAERS: 1US FAERS
218AgeusiaFAERS: 1US FAERS
219Altered state of consciousnessFAERS: 1US FAERS
220Anaphylactoid ReactionFAERS: 1US FAERS
221AngioplastyFAERS: 1US FAERS
222Anorectal discomfortFAERS: 1US FAERS
223Anti-platelet antibody negativeFAERS: 1US FAERS
224Aortic occlusionFAERS: 1US FAERS
225Apallic syndromeFAERS: 1US FAERS
226AphoniaFAERS: 1US FAERS
227Arterial InjuryFAERS: 1US FAERS
228Arterial therapeutic procedureFAERS: 1US FAERS
229AsphyxiaFAERS: 1US FAERS
230AsthmaFAERS: 1US FAERS
231Atherosclerotic plaque ruptureFAERS: 1US FAERS
232Atrial FlutterFAERS: 1US FAERS
233Autoimmune neutropeniaFAERS: 1US FAERS
234Autonomic nervous system imbalanceFAERS: 1US FAERS
235BabesiosisFAERS: 1US FAERS
236Bacterial disease carrierFAERS: 1US FAERS
237Basal cell carcinomaFAERS: 1US FAERS
238Blood blisterFAERS: 1US FAERS
239Blood iron decreasedFAERS: 1US FAERS
240Blood potassium decreasedFAERS: 1US FAERS
241Blood pressure fluctuationFAERS: 1US FAERS
242Blood pressure immeasurableFAERS: 1US FAERS
243Blood triglycerides increasedFAERS: 1US FAERS
244Blue Toe SyndromeFAERS: 1US FAERS
245Bowel movement irregularityFAERS: 1US FAERS
246Brain DeathFAERS: 1US FAERS
247BronchiectasisFAERS: 1US FAERS
248BronchitisFAERS: 1US FAERS
249BronchopneumoniaFAERS: 1US FAERS
250Burning sensationFAERS: 1US FAERS
251BursitisFAERS: 1US FAERS
252Cardiac perforationFAERS: 1US FAERS
253Cardiac pseudoaneurysmFAERS: 1US FAERS
254Cardiac stress test abnormalFAERS: 1US FAERS
255CellulitisFAERS: 1US FAERS
256Central nervous system lesionFAERS: 1US FAERS
257Cerebral ThrombosisFAERS: 1US FAERS
258ChokingFAERS: 1US FAERS
259Coagulation time shortenedFAERS: 1US FAERS
260Cold sweatFAERS: 1US FAERS
261Completed SuicideFAERS: 1US FAERS
262Complication associated with deviceFAERS: 1US FAERS
263Coronary artery reocclusionFAERS: 1US FAERS
264CryingFAERS: 1US FAERS
265CystitisFAERS: 1US FAERS
266Dark circles under eyesFAERS: 1US FAERS
267DementiaFAERS: 1US FAERS
268Depressed Level of ConsciousnessFAERS: 1US FAERS
269Device FailureFAERS: 1US FAERS
270Device connection issueFAERS: 1US FAERS
271Diaphragmatic spasmFAERS: 1US FAERS
272Diverticular perforationFAERS: 1US FAERS
273DiverticulumFAERS: 1US FAERS
274Drug level below therapeuticFAERS: 1US FAERS
275Duodenal UlcerFAERS: 1US FAERS
276DysphoniaFAERS: 1US FAERS
277DysuriaFAERS: 1US FAERS
278Electrocardiogram abnormalFAERS: 1US FAERS
279Embolic cerebral infarctionFAERS: 1US FAERS
280EmbolismFAERS: 1US FAERS
281Emotional distressFAERS: 1US FAERS
282Endotracheal intubation complicationFAERS: 1US FAERS
283Enzyme abnormalityFAERS: 1US FAERS
284EosinophiliaFAERS: 1US FAERS
285Epigastric discomfortFAERS: 1US FAERS
286ErysipelasFAERS: 1US FAERS
287Erythema NodosumFAERS: 1US FAERS
288ExcoriationFAERS: 1US FAERS
289Expired product administeredFAERS: 1US FAERS
290Extra dose administeredFAERS: 1US FAERS
291Eye painFAERS: 1US FAERS
292Femoral artery occlusionFAERS: 1US FAERS
293Flank PainFAERS: 1US FAERS
294Food aversionFAERS: 1US FAERS
295Full blood count decreasedFAERS: 1US FAERS
296Gastrointestinal angiodysplasia haemorrhagicFAERS: 1US FAERS
297Gastrointestinal angiodysplasiaFAERS: 1US FAERS
298Gastrointestinal ulcerFAERS: 1US FAERS
299General symptomFAERS: 1US FAERS
300Head discomfortFAERS: 1US FAERS
301Helicobacter test positiveFAERS: 1US FAERS
302HemiparesisFAERS: 1US FAERS
303Hepatitis CFAERS: 1US FAERS
304Hepatobiliary scan abnormalFAERS: 1US FAERS
305Hypertensive crisisFAERS: 1US FAERS
306HypertransaminasaemiaFAERS: 1US FAERS
307Iliac artery stenosisFAERS: 1US FAERS
308Impaired driving abilityFAERS: 1US FAERS
309Inappropriate schedule of drug administrationFAERS: 1US FAERS
310Incarcerated herniaFAERS: 1US FAERS
311Incorrect drug dosage form administeredFAERS: 1US FAERS
312Infusion site infectionFAERS: 1US FAERS
313Intestinal ObstructionFAERS: 1US FAERS
314Joint stiffnessFAERS: 1US FAERS
315Labile blood pressureFAERS: 1US FAERS
316LaryngitisFAERS: 1US FAERS
317LeukopeniaFAERS: 1SIDER
US FAERS
318Limb discomfortFAERS: 1US FAERS
319LymphadenopathyFAERS: 1US FAERS
320LymphangitisFAERS: 1US FAERS
321Lymphocytic infiltrationFAERS: 1US FAERS
322MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
323Malignant HypertensionFAERS: 1US FAERS
324Mallory-Weiss SyndromeFAERS: 1US FAERS
325MalnutritionFAERS: 1US FAERS
326Mechanical ventilationFAERS: 1US FAERS
327Mediastinal massFAERS: 1US FAERS
328Medical device implantationFAERS: 1US FAERS
329Medication residue presentFAERS: 1US FAERS
330Mental status changesFAERS: 1US FAERS
331MiliariaFAERS: 1US FAERS
332MonoplegiaFAERS: 1US FAERS
333Mouth swellingFAERS: 1US FAERS
334MultimorbidityFAERS: 1US FAERS
335Muscle strainFAERS: 1US FAERS
336Musculoskeletal discomfortFAERS: 1US FAERS
337Myasthenia GravisFAERS: 1US FAERS
338MyopathyFAERS: 1US FAERS
339Nasal PolypsFAERS: 1US FAERS
340Neurogenic BowelFAERS: 1US FAERS
341Night sweatsFAERS: 1US FAERS
342Ocular discomfortFAERS: 1US FAERS
343Ocular icterusFAERS: 1US FAERS
344Oral candidiasisFAERS: 1US FAERS
345Oral infectionFAERS: 1US FAERS
346Oral mucosal erythemaFAERS: 1US FAERS
347Oral painFAERS: 1US FAERS
348Pain of skinFAERS: 1US FAERS
349Pathogen resistanceFAERS: 1US FAERS
350Peripheral artery thrombosisFAERS: 1US FAERS
351Platelet function test normalFAERS: 1US FAERS
352PneumobiliaFAERS: 1US FAERS
353PolyuriaFAERS: 1US FAERS
354Poor quality drug administeredFAERS: 1US FAERS
355Postinfarction anginaFAERS: 1US FAERS
356Product dose omissionFAERS: 1US FAERS
357Product physical issueFAERS: 1US FAERS
358Prothrombin time abnormalFAERS: 1US FAERS
359PsoriasisFAERS: 1US FAERS
360Pulmonary EmbolismFAERS: 1US FAERS
361Pulmonary congestionFAERS: 1US FAERS
362Pulmonary sepsisFAERS: 1US FAERS
363Pulmonary thrombosisFAERS: 1US FAERS
364Quality of life decreasedFAERS: 1US FAERS
365Radiation proctitisFAERS: 1US FAERS
366Rash erythematousFAERS: 1US FAERS
367Renal cystFAERS: 1US FAERS
368Renal painFAERS: 1US FAERS
369Respiratory tract congestionFAERS: 1US FAERS
370Retinal DetachmentFAERS: 1US FAERS
371Retrograde p-wavesFAERS: 1US FAERS
372RhabdomyolysisFAERS: 1US FAERS
373Rheumatoid ArthritisFAERS: 1US FAERS
374Rotator cuff syndromeFAERS: 1US FAERS
375Ruptured cerebral aneurysmFAERS: 1US FAERS
376SarcoidosisFAERS: 1US FAERS
377ScabFAERS: 1US FAERS
378Sinus polypFAERS: 1US FAERS
379Skin irritationFAERS: 1US FAERS
380Skin necrosisFAERS: 1US FAERS
381Skin reactionFAERS: 1US FAERS
382Sleep disorder due to general medical condition, insomnia typeFAERS: 1US FAERS
383SluggishnessFAERS: 1US FAERS
384Soft tissue massFAERS: 1US FAERS
385Stevens-Johnson SyndromeFAERS: 1US FAERS
386StomatitisFAERS: 1US FAERS
387Stress ulcerFAERS: 1US FAERS
388Stroke in evolutionFAERS: 1US FAERS
389Supraventricular tachycardiaFAERS: 1US FAERS
390Surgical failureFAERS: 1US FAERS
391TachycardiaFAERS: 1US FAERS
392TensionFAERS: 1US FAERS
393Therapeutic procedureFAERS: 1US FAERS
394Throat cancerFAERS: 1US FAERS
395Tongue blisteringFAERS: 1US FAERS
396Tongue discomfortFAERS: 1US FAERS
397Tongue exfoliationFAERS: 1US FAERS
398Tooth InfectionFAERS: 1US FAERS
399Tumour haemorrhageFAERS: 1US FAERS
400Unevaluable eventFAERS: 1US FAERS
401Upper-airway cough syndromeFAERS: 1US FAERS
402Urethral ObstructionFAERS: 1US FAERS
403Urinary tract infectionFAERS: 1US FAERS
404Urine flow decreasedFAERS: 1US FAERS
405Uterine PolypFAERS: 1US FAERS
406Vaginal DischargeFAERS: 1US FAERS
407Vascular bypass dysfunctionFAERS: 1US FAERS
408Vascular stenosisFAERS: 1US FAERS
409Vascular stent occlusionFAERS: 1US FAERS
410Vascular stent restenosisFAERS: 1US FAERS
411VasculitisFAERS: 1US FAERS
412WheezingFAERS: 1US FAERS
413White blood cell count abnormalFAERS: 1US FAERS
414Wrong technique in drug usage processFAERS: 1US FAERS
415YawningFAERS: 1US FAERS
416effusionFAERS: 1US FAERS
417Anaphylactic shockSIDER
418Blood and lymphatic system disordersSIDER
419DermatitisSIDER
420Thrombocytopenic purpuraSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120329

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.