MetaADEDB 2.0 @ LMMD
Nystatin
(VQOXZBDYSJBXMA-RKEBNKJGSA-N)
Structure
SMILES
OC1CCC(O)C(O)C[C@]2(O)CC(O)C(C(O2)CC(/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@@H]([C@H]([C@H]([C@@H](OC(=O)CC(CC(C1)O)O)C)C)O)C)O[C@H]1O[C@H](C)[C@H]([C@@H]([C@@H]1O)N)O)C(=O)O
Type(s)
Approved; Vet_approved
ATC code(s)
A07AA02; D01AA01; G01AA01; G01AA51
Molecular Formula:
C47H75NO17
Molecular Weight:
926.095
Log P:
1.6360
Hydrogen Bond Acceptor:
18
Hydrogen Bond Donor:
12
TPSA:
319.61
CAS Number(s):
1400-61-9
Synonym(s)
1.
Nystatin
2.
Fungicidin
3.
Mycostatin
4.
Nilstat
5.
Nystatin A1
6.
Nystatin A2
7.
Nystatin A3
8.
Nystatin G
9.
Stamicin
10.
Stamycin
External Link(s)
MeSHD009761
PubChem Compound6433272
ChEBI473992
DrugBankDB00646
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 29
Canada Vigilance: 1		Canada Vigilance
US FAERS
2Burning sensationFAERS: 13US FAERS
3HypersensitivityFAERS: 12
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
4PruritusFAERS: 12
Canada Vigilance: 4		Canada Vigilance
SIDER
US FAERS
5ErythemaFAERS: 10
Canada Vigilance: 5		Canada Vigilance
OFFSIDES
US FAERS
6NauseaFAERS: 9
Canada Vigilance: 4		Canada Vigilance
OFFSIDES
SIDER
US FAERS
7VomitingFAERS: 7
Canada Vigilance: 4		Canada Vigilance
SIDER
US FAERS
8Application site painFAERS: 6US FAERS
9CandidiasisFAERS: 6US FAERS
10DysgeusiaFAERS: 6US FAERS
11PregnancyFAERS: 6US FAERS
12Rash erythematousFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
13Weight decreasedFAERS: 6US FAERS
14MalaiseFAERS: 5US FAERS
15Medication ErrorFAERS: 5
Canada Vigilance: 2		Canada Vigilance
US FAERS
16Oral painFAERS: 5US FAERS
17Application site erythemaFAERS: 4US FAERS
18Application site reactionFAERS: 4US FAERS
19HeadacheFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
20Throat irritationFAERS: 4US FAERS
21Abdominal discomfortFAERS: 3
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
SIDER
US FAERS
22ArthralgiaFAERS: 3US FAERS
23Drug dispensing errorFAERS: 3US FAERS
24DyspepsiaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
25Incorrect route of drug administrationFAERS: 3US FAERS
26Intestinal PerforationFAERS: 3US FAERS
27Lip swellingFAERS: 3US FAERS
28PalpitationsFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
29Product taste abnormalFAERS: 3US FAERS
30TachycardiaFAERS: 3SIDER
US FAERS
31UrticariaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
32Application site rashFAERS: 2US FAERS
33Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
34AstheniaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
35Chest PainFAERS: 2OFFSIDES
US FAERS
36Chest discomfortFAERS: 2US FAERS
37ChillsFAERS: 2US FAERS
38DiscomfortFAERS: 2US FAERS
39DizzinessFAERS: 2
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
40Drug exposure during pregnancyFAERS: 2OFFSIDES
US FAERS
41Drug ineffective for unapproved indicationFAERS: 2US FAERS
42Drug prescribing errorFAERS: 2US FAERS
43EczemaFAERS: 2SIDER
US FAERS
44Feeding disorder neonatalFAERS: 2US FAERS
45FlushingFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
46HyperparathyroidismFAERS: 2US FAERS
47NervousnessFAERS: 2US FAERS
48No adverse eventFAERS: 2US FAERS
49Oral candidiasisFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
50Oropharyngeal painFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
51OverdoseFAERS: 2US FAERS
52PainFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
53Pharmaceutical product complaintFAERS: 2US FAERS
54PneumoniaFAERS: 2US FAERS
55Product use issueFAERS: 2US FAERS
56RetchingFAERS: 2US FAERS
57SepsisFAERS: 2US FAERS
58Sinus painFAERS: 2US FAERS
59ToothacheFAERS: 2US FAERS
60Toxic Epidermal NecrolysisFAERS: 2US FAERS
61Vulvovaginal mycotic infectionFAERS: 2US FAERS
62AbscessFAERS: 1US FAERS
63Accidental exposure to productFAERS: 1US FAERS
64Accidental exposure to product by childFAERS: 1US FAERS
65Accidental exposureFAERS: 1US FAERS
66Acute sinusitisFAERS: 1OFFSIDES
US FAERS
67Adverse eventFAERS: 1US FAERS
68AgeusiaFAERS: 1US FAERS
69AgitationFAERS: 1US FAERS
70Alanine Aminotransferase IncreasedFAERS: 1OFFSIDES
US FAERS
71Alanine aminotransferase abnormalFAERS: 1US FAERS
72AlopeciaFAERS: 1US FAERS
73AngioedemaFAERS: 1OFFSIDES
US FAERS
74AnorexiaFAERS: 1OFFSIDES
US FAERS
75AnxietyFAERS: 1OFFSIDES
US FAERS
76Application site eczemaFAERS: 1US FAERS
77Application site irritationFAERS: 1US FAERS
78Application site pruritusFAERS: 1US FAERS
79Application site warmthFAERS: 1US FAERS
80Aspartate aminotransferase abnormalFAERS: 1US FAERS
81AsthmaFAERS: 1OFFSIDES
US FAERS
82Blood glucose increasedFAERS: 1US FAERS
83Bone painFAERS: 1US FAERS
84CellulitisFAERS: 1OFFSIDES
US FAERS
85CheilitisFAERS: 1US FAERS
86Citrobacter infectionFAERS: 1US FAERS
87Coating in mouthFAERS: 1US FAERS
88ConstipationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
89CryingFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
90DermatitisFAERS: 1SIDER
US FAERS
91Device breakageFAERS: 1US FAERS
92Device malfunctionFAERS: 1US FAERS
93DroolingFAERS: 1US FAERS
94Drug dose omissionFAERS: 1US FAERS
95Dry skinFAERS: 1US FAERS
96DysphoniaFAERS: 1US FAERS
97Emotional distressFAERS: 1OFFSIDES
US FAERS
98Exfoliative rashFAERS: 1US FAERS
99Eye irritationFAERS: 1US FAERS
100Eye painFAERS: 1US FAERS
101Eyelid exfoliationFAERS: 1US FAERS
102Facial PainFAERS: 1US FAERS
103FatigueFAERS: 1OFFSIDES
US FAERS
104Feeling abnormalFAERS: 1US FAERS
105Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
106Gastric ulcerFAERS: 1OFFSIDES
US FAERS
107Gastrointestinal sounds abnormalFAERS: 1US FAERS
108GlossitisFAERS: 1US FAERS
109Growth retardationFAERS: 1US FAERS
110Head discomfortFAERS: 1US FAERS
111HypersomniaFAERS: 1US FAERS
112Impaired work abilityFAERS: 1US FAERS
113ImpetigoFAERS: 1US FAERS
114Inappropriate schedule of drug administrationFAERS: 1US FAERS
115Incorrect dose administeredFAERS: 1US FAERS
116InfectionFAERS: 1OFFSIDES
US FAERS
117Initial insomniaFAERS: 1US FAERS
118Intentional product misuseFAERS: 1US FAERS
119Intentional product use issueFAERS: 1US FAERS
120Irritable Bowel SyndromeFAERS: 1US FAERS
121Joint swellingFAERS: 1US FAERS
122LaryngitisFAERS: 1US FAERS
123LeukocytosisFAERS: 1US FAERS
124LipomaFAERS: 1US FAERS
125MalabsorptionFAERS: 1US FAERS
126Maternal exposure during pregnancyFAERS: 1US FAERS
127Middle insomniaFAERS: 1US FAERS
128Mouth swellingFAERS: 1US FAERS
129Muscle tightnessFAERS: 1US FAERS
130Musculoskeletal stiffnessFAERS: 1US FAERS
131NephrolithiasisFAERS: 1US FAERS
132NeuralgiaFAERS: 1OFFSIDES
US FAERS
133Pathogen resistanceFAERS: 1OFFSIDES
US FAERS
134Peptic UlcerFAERS: 1US FAERS
135Peripheral swellingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
136PharyngitisFAERS: 1US FAERS
137Poor quality drug administeredFAERS: 1US FAERS
138Product administered at inappropriate siteFAERS: 1US FAERS
139Product contaminationFAERS: 1US FAERS
140Product design issueFAERS: 1US FAERS
141Product label issueFAERS: 1US FAERS
142Product package associated injuryFAERS: 1US FAERS
143Product packaging issueFAERS: 1US FAERS
144Product quality issueFAERS: 1US FAERS
145Product residue presentFAERS: 1US FAERS
146Product substitution issueFAERS: 1US FAERS
147Product tamperingFAERS: 1US FAERS
148Reflux gastritisFAERS: 1US FAERS
149Respiratory arrestFAERS: 1US FAERS
150ScabFAERS: 1OFFSIDES
US FAERS
151Skin irritationFAERS: 1US FAERS
152SneezingFAERS: 1US FAERS
153Stevens-Johnson SyndromeFAERS: 1OFFSIDES
SIDER
US FAERS
154StomatitisFAERS: 1SIDER
US FAERS
155StressFAERS: 1US FAERS
156TinnitusFAERS: 1US FAERS
157Unresponsive to stimuliFAERS: 1US FAERS
158Upper airway obstructionFAERS: 1US FAERS
159Upper respiratory tract inflammationFAERS: 1US FAERS
160Urinary IncontinenceFAERS: 1US FAERS
161VasculitisFAERS: 1US FAERS
162Vitamin D DeficiencyFAERS: 1US FAERS
163Vulvovaginal burning sensationFAERS: 1US FAERS
164VulvovaginitisFAERS: 1US FAERS
165WheezingFAERS: 1US FAERS
166Wrong drug administeredFAERS: 1US FAERS
167nervous system disorderFAERS: 1US FAERS
168Abdominal PainOFFSIDES
169Abnormal visionOFFSIDES
170ActinomycosisOFFSIDES
171Acute bronchitisOFFSIDES
172Acute graft versus host disease in intestineOFFSIDES
173Acute myocardial infarctionOFFSIDES
174AgoraphobiaOFFSIDES
175AgraphiaOFFSIDES
176Albumin globulin ratio increasedOFFSIDES
177Altered bowel functionOFFSIDES
178AlveolitisOFFSIDES
179Ammonia increasedOFFSIDES
180AmnesiaOFFSIDES
181AmphetaminesOFFSIDES
182Anaphylactic shockSIDER
183Anaphylactoid ReactionSIDER
184AngerOFFSIDES
185AnhedoniaOFFSIDES
186Anticonvulsant drug level above therapeuticOFFSIDES
187Antidepressant drug clearance decreasedOFFSIDES
188Antiviral drug level above therapeuticOFFSIDES
189AnuriaCanada Vigilance: 1Canada Vigilance
190ArthritisOFFSIDES
191AscitesOFFSIDES
192Aspiration PneumoniaOFFSIDES
193AtelectasisOFFSIDES
194AtherosclerosisOFFSIDES
195Atrial tachycardiaOFFSIDES
196AuraOFFSIDES
197Back PainCanada Vigilance: 1Canada Vigilance
198Bacteria urine identifiedOFFSIDES
199Bacterial sepsisOFFSIDES
200Bile duct necrosisOFFSIDES
201Blood GlucoseOFFSIDES
202Blood albumin decreasedOFFSIDES
203Blood alkaline phosphatase increasedOFFSIDES
204Blood alkaline phosphataseOFFSIDES
205Blood amylase increasedOFFSIDES
206Blood cholesterolOFFSIDES
207Blood cholinesterase decreasedOFFSIDES
208Blood count abnormalOFFSIDES
209Blood creatinine decreasedOFFSIDES
210Blood creatinine increasedOFFSIDES
211Blood gases abnormalOFFSIDES
212Blood glucose decreasedOFFSIDES
213Blood glucose fluctuationOFFSIDES
214Blood immunoglobulin EOFFSIDES
215Blood potassium decreasedOFFSIDES
216Blood potassium increasedOFFSIDES
217Blood potassiumOFFSIDES
218Blood pressure fluctuationOFFSIDES
219Blood sodiumOFFSIDES
220Blood thyroid stimulating hormoneOFFSIDES
221Blood uric acid abnormalOFFSIDES
222Blurred visionOFFSIDES
223Bone density decreasedOFFSIDES
224BradycardiaOFFSIDES
225BronchiectasisOFFSIDES
226BronchitisOFFSIDES
227BronchospasmSIDER
228BruxismOFFSIDES
229Candidiasis of vaginaOFFSIDES
230Capillary Leak SyndromeOFFSIDES
231Cardiac HypertrophyOFFSIDES
232Cardiac stress test abnormalOFFSIDES
233Cardioactive drug levelOFFSIDES
234Cardioactive drug level increasedOFFSIDES
235Catheter related complicationOFFSIDES
236Catheter related infectionOFFSIDES
237Catheter site cellulitisOFFSIDES
238Central nervous system lesionOFFSIDES
239Cervicobrachial syndromeOFFSIDES
240ChromaturiaOFFSIDES
241Chronic Obstructive Airway DiseaseOFFSIDES
242Chronic respiratory failureOFFSIDES
243Chronic ulcerative colitisOFFSIDES
244Cleft PalateOFFSIDES
245Cognitive deteriorationOFFSIDES
246Cogwheel RigidityOFFSIDES
247Cold sweatOFFSIDES
248ColitisOFFSIDES
249ConfabulationOFFSIDES
250Congenital tricuspid valve incompetenceOFFSIDES
251Conjunctival depositOFFSIDES
252Cotard's syndromeOFFSIDES
253Cubital Tunnel SyndromeOFFSIDES
254Culture positiveOFFSIDES
255Culture wound positiveOFFSIDES
256CyanosisCanada Vigilance: 1Canada Vigilance
257Cystic FibrosisOFFSIDES
258DebridementOFFSIDES
259DehydrationOFFSIDES
260DemyelinationOFFSIDES
261Dental cariesOFFSIDES
262Dental prosthesis userOFFSIDES
263Depressed moodOFFSIDES
264Device related infectionOFFSIDES
265DiabetesOFFSIDES
266Diabetes mellitus inadequate controlOFFSIDES
267DiarrheaOFFSIDES
268DiplopiaOFFSIDES
269Disease ProgressionOFFSIDES
270Disease recurrenceOFFSIDES
271Disseminated Intravascular CoagulationOFFSIDES
272Distress gastrointestinalSIDER
273DiverticulumOFFSIDES
274DrowsinessOFFSIDES
275Drug toxicityOFFSIDES
276Drug withdrawal headacheOFFSIDES
277Duodenal perforationOFFSIDES
278DuodenitisOFFSIDES
279Dysthymic DisorderOFFSIDES
280DysuriaOFFSIDES
281Ear congestionOFFSIDES
282Ejection Fraction DecreasedOFFSIDES
283Electrocardiogram ST segment abnormalOFFSIDES
284Electrolyte imbalanceCanada Vigilance: 1Canada Vigilance
285EmbolismOFFSIDES
286Endodontic procedureOFFSIDES
287Enterococcal infectionOFFSIDES
288Enterococcal sepsisOFFSIDES
289Enterovesical FistulaOFFSIDES
290EpilepsyOFFSIDES
291EpistaxisOFFSIDES
292Erythema MultiformeSIDER
293ErythropeniaOFFSIDES
294Essential HypertensionOFFSIDES
295ExcoriationOFFSIDES
296Eye InfectionOFFSIDES
297Failure to ThriveOFFSIDES
298Fatty LiverOFFSIDES
299Febrile NeutropeniaOFFSIDES
300Feeding problem in childOFFSIDES
301Feeling ColdOFFSIDES
302FibromyalgiaOFFSIDES
303FlatulenceOFFSIDES
304Fluid overloadOFFSIDES
305FolliculitisOFFSIDES
306GangreneOFFSIDES
307GastroenteritisOFFSIDES
308General physical health deteriorationOFFSIDES
309General symptomCanada Vigilance: 1Canada Vigilance
310GoiterOFFSIDES
311Granulocyte count increasedOFFSIDES
312GranulomaOFFSIDES
313HemiparesisOFFSIDES
314HemiplegiaOFFSIDES
315HemothoraxOFFSIDES
316Heparin-induced thrombocytopeniaOFFSIDES
317Hepatic necrosisOFFSIDES
318Hepatitis B positiveOFFSIDES
319Hepatitis BOFFSIDES
320HepatitisOFFSIDES
321HepatoblastomaOFFSIDES
322HoarsenessOFFSIDES
323Human polyomavirus infectionOFFSIDES
324HydronephrosisOFFSIDES
325Hypertensive heart diseaseOFFSIDES
326HypomaniaOFFSIDES
327HypophagiaOFFSIDES
328HypoxiaOFFSIDES
329Immune reconstitution syndromeOFFSIDES
330Infusion site infectionOFFSIDES
331Infusion site painOFFSIDES
332Intervertebral Disc DegenerationOFFSIDES
333Joint sprainOFFSIDES
334Kidney Diseases22863853CTD
335Kidney FailureOFFSIDES
336LacerationOFFSIDES
337Left atrial dilatationOFFSIDES
338LethargyOFFSIDES
339LeukoplakiaOFFSIDES
340Lichen PlanusOFFSIDES
341Life expectancy shortenedOFFSIDES
342Lip erythemaCanada Vigilance: 1Canada Vigilance
343Lip exfoliationOFFSIDES
344Listeria sepsisOFFSIDES
345Liver carcinoma rupturedOFFSIDES
346Liver transplant rejectionOFFSIDES
347Loose toothOFFSIDES
348Lumbar radiculopathyOFFSIDES
349Lung consolidationOFFSIDES
350Lupus pneumonitisOFFSIDES
351Lymph node palpableOFFSIDES
352Lymphocyte count decreasedOFFSIDES
353Malignant HypertensionOFFSIDES
354Malignant tumour excisionOFFSIDES
355MastectomyOFFSIDES
356MegacolonOFFSIDES
357Mental status changesOFFSIDES
358Metabolic acidosisOFFSIDES
359Mixed liver injuryOFFSIDES
360Mouth irritationSIDER
361Muscle necrosisOFFSIDES
362Musculoskeletal discomfortSIDER
363MyalgiaSIDER
364Mycoses16374455CTD
365Nasal sinus drainageOFFSIDES
366NasopharyngitisOFFSIDES
367Necrosis22863853CTD
368Negative thoughtsOFFSIDES
369Neutrophil count decreasedOFFSIDES
370NoduleOFFSIDES
371Ocular icterusOFFSIDES
372OliguriaOFFSIDES
373Oral fungal infectionOFFSIDES
374Oral mucosal erythemaCanada Vigilance: 1Canada Vigilance
375OrthopneaOFFSIDES
376OsteopeniaOFFSIDES
377OsteoporosisOFFSIDES
378PCO2 increasedOFFSIDES
379Pericarditis lupusOFFSIDES
380PericarditisOFFSIDES
381PeriodontitisOFFSIDES
382Peripheral embolismOFFSIDES
383Pharyngeal swellingCanada Vigilance: 1Canada Vigilance
384Pharyngolaryngeal PainOFFSIDES
385Physical disabilityOFFSIDES
386Pneumocystis jiroveci pneumoniaOFFSIDES
387PolydactylyOFFSIDES
388Polyomavirus interstitial nephritisOFFSIDES
389PolyuriaOFFSIDES
390Post procedural complicationOFFSIDES
391Procedural complicationOFFSIDES
392Product complaintCanada Vigilance: 1Canada Vigilance
393Prolonged expirationOFFSIDES
394PseudarthrosisOFFSIDES
395Pulmonary HypertensionOFFSIDES
396Pulmonary Valve StenosisOFFSIDES
397Pulmonary congestionOFFSIDES
398PurpuraCanada Vigilance: 1Canada Vigilance
399Purulent dischargeOFFSIDES
400Quality of life decreasedOFFSIDES
401Radiation skin injuryOFFSIDES
402Radiotherapy to brainOFFSIDES
403Rectal polypOFFSIDES
404Renal tubular necrosisOFFSIDES
405Respiratory FailureOFFSIDES
406Restrictive pulmonary diseaseOFFSIDES
407RhinalgiaOFFSIDES
408RhinorrheaOFFSIDES
409Right atrial dilatationOFFSIDES
410SchizophreniaOFFSIDES
411Septic ShockOFFSIDES
412Serum SicknessOFFSIDES
413Sinus bradycardiaOFFSIDES
414SinusitisOFFSIDES
415SomnolenceCanada Vigilance: 1Canada Vigilance
416Spinal fusion surgeryOFFSIDES
417SpondylolisthesisOFFSIDES
418Sudden deathOFFSIDES
419Superficial ThrombophlebitisOFFSIDES
420SyncopeCanada Vigilance: 1Canada Vigilance
421TendinitisOFFSIDES
422ThoracotomyOFFSIDES
423ThymomaOFFSIDES
424Tooth ExtractionOFFSIDES
425Tooth InfectionOFFSIDES
426Tooth LossOFFSIDES
427Transaminases abnormalOFFSIDES
428Transaminases increasedOFFSIDES
429TremorCanada Vigilance: 1Canada Vigilance
430Troponin increasedOFFSIDES
431Urinary tract infection enterococcalOFFSIDES
432Urinary tract infection pseudomonalOFFSIDES
433Vaginal mycosisOFFSIDES
434Vascular insufficiencyOFFSIDES
435Venous thrombosis limbOFFSIDES
436Ventricular FibrillationOFFSIDES
437VertigoCanada Vigilance: 1Canada Vigilance
438Waist circumference increasedOFFSIDES
439Weight GainOFFSIDES
440colonoscopyOFFSIDES
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