MetaADEDB 2.0 @ LMMD
Phentolamine
(MRBDMNSDAVCSSF-UHFFFAOYSA-N)
Structure
SMILES
Cc1ccc(cc1)N(c1cccc(c1)O)CC1=NCCN1
Type(s)
Approved
ATC code(s)
C04AB01; V03AB36
Molecular Formula:
C17H19N3O
Molecular Weight:
281.352
Log P:
2.6048
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
2
TPSA:
47.86
CAS Number(s):
50-60-2; 73-05-2
Synonym(s)
1.
Phentolamine
2.
Fentolamin
3.
Phentolamine Mesilate
4.
Phentolamine Mesylate
5.
Phentolamine Methanesulfonate
6.
Phentolamine Mono-hydrochloride
7.
Regitine
8.
Regityn
9.
Rogitine
10.
Z-Max
11.
Mesilate, Phentolamine
12.
Mesylate, Phentolamine
13.
Methanesulfonate, Phentolamine
14.
Mono-hydrochloride, Phentolamine
15.
Phentolamine Mono hydrochloride
External Link(s)
MeSHD010646
PubChem Compound5775
4920903
BindingDB31046
50008789
ChEBI8081
CHEMBLCHEMBL597
DrugBankDB00692
DrugCentral2142
IUPHAR/BPS Guide to PHARMACOLOGY502
KEGGdr:D08362
Therapeutic Target DatabaseD01JUF
ZINC20251
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1CyanosisFAERS: 2US FAERS
2OverdoseFAERS: 2US FAERS
3Blood pressure fluctuationFAERS: 1US FAERS
4Drug prescribing errorFAERS: 1US FAERS
5HypotensionFAERS: 1

View details

811997
1184511
1310543
2565755
2894880
6117801
6176798
9152364
12598489
15682801
 		CTD
SIDER
US FAERS
6Malignant neoplasm progressionFAERS: 1US FAERS
7Medication ErrorFAERS: 1US FAERS
8MetastasisFAERS: 1US FAERS
9Abdominal PainSIDER
10Acute Coronary Syndrome18072128CTD
SIDER
11Angina Pectoris6305298CTD
SIDER
12Aortic Valve Insufficiency7258732CTD
13AstheniaSIDER
14Atrioventricular Block731879CTD
15Bradycardia960094
6707926
7426836		CTD
SIDER
16Brain Edema20324CTD
17Chemical and Drug Induced Liver Injury2886651CTD
18Chest Pain1620184
3578343
16326260		CTD
SIDER
19Cocaine-Related Disorders18072128
20417385		CTD
20Coronary Stenosis14607445CTD
21Diarrhea12152116CTD
22Disruptive, Impulse Control, and Conduct Disorders6093179CTD
23Dizziness12152116CTD
SIDER
24Drug Overdose15682801CTD
25Dyspareunia1719248
8386779		CTD
26Emotional distressCanada Vigilance: 1Canada Vigilance
27Epilepsy731879CTD
28Erectile dysfunction

View details

7735362
10098948
10233493
12152116
 		CTD
29Fibrosis6230880CTD
30Flushing10233493CTD
SIDER
31Gastrointestinal PainSIDER
32Headache12152116CTD
SIDER
33Heart Diseases6131755CTD
34Heart failure446138
6160553
7258732		CTD
35Hyperalgesia2833584
7753402
9613798		CTD
36Hyperglycemia1350317
2989959
22305719		CTD
37Hypesthesia20831927CTD
38Hypotension, Orthostatic6876810CTD
39HypotensiveSIDER
40Impotence, Vasculogenic1719248CTD
41Inflammation20020792CTD
42Injection Site ReactionSIDER
43Injection site painSIDER
44Ischemia2764457CTD
45Lipoma24141031CTD
46Mitral Valve Insufficiency7258732CTD
47Myocardial Infarction6160553
7058000
11407498		CTD
SIDER
48Myocardial Ischemia1620184
2429111
8795497		CTD
49Myoclonus37558
6104728		CTD
50Nausea12152116CTD
SIDER
51Necrosis2764457
6131755		CTD
52Nerve Degeneration20020792CTD
53Neurobehavioral Manifestations499336
27640743		CTD
54Oral painSIDER
55Pain8773445CTD
SIDER
56Peptic UlcerSIDER
57Personality Disorders575199CTD
58Post procedural painSIDER
59Priapism1719248
1984077
7713130		CTD
60PruritusSIDER
61Rhinitis12152116CTD
62Seizures8224101CTD
63Sinoatrial Block731879CTD
64Spasm623942CTD
65Tachycardia, Ventricular4005090CTD
66Tachycardia

View details

6176798
6876810
7426836
12152116
 		CTD
SIDER
67Thrombosis7055868CTD
68Ventricular Dysfunction, Left4696794
6160553		CTD
69Ventricular Dysfunction12010770CTD
70Vomiting12152116CTD
SIDER
71nervous system disorderSIDER
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