MetaADEDB 2.0 @ LMMD
Maloprim
(WKSAUQYGYAYLPV-UHFFFAOYSA-N)
Structure
SMILES
CCc1nc(N)nc(c1c1ccc(cc1)Cl)N
Type(s)
Approved; Investigational; Vet_approved
ATC code(s)
P01BD01; P01BD51; P01BF04
Molecular Formula:
C12H13ClN4
Molecular Weight:
248.711
Log P:
3.6862
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
77.82
CAS Number(s):
58-14-0
Synonym(s)
1.
Maloprim
2.
Folaprim
External Link(s)
MeSHC001678
PubChem Compound4993
BindingDB18512
ChEBI8673
CHEMBLCHEMBL36
DrugBankDB00205
DrugCentral2332
IUPHAR/BPS Guide to PHARMACOLOGY4800
KEGGcpd:C07391
dr:D00488
Therapeutic Target DatabaseD0C0SK
ZINC57464
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1NauseaFAERS: 16US FAERS
2NeutropeniaFAERS: 7US FAERS
3VomitingFAERS: 7SIDER
US FAERS
4Toxicity to various agentsFAERS: 4US FAERS
5Abdominal discomfortFAERS: 3US FAERS
6Accidental exposure to productFAERS: 3US FAERS
7HeadacheFAERS: 3US FAERS
8HypersensitivityFAERS: 3SIDER
US FAERS
9InfectionFAERS: 3US FAERS
10Product contaminationFAERS: 3US FAERS
11PruritusFAERS: 3US FAERS
12Accidental overdoseFAERS: 2US FAERS
13Cerebrovascular accidentFAERS: 2US FAERS
14InfluenzaFAERS: 2US FAERS
15MalaiseFAERS: 2US FAERS
16Myocardial InfarctionFAERS: 2US FAERS
17NephrolithiasisFAERS: 2US FAERS
18SomnolenceFAERS: 2US FAERS
19ThrombocytopeniaFAERS: 2SIDER
US FAERS
20ThrombosisFAERS: 2US FAERS
21UrticariaFAERS: 2US FAERS
22White blood cell count decreasedFAERS: 2US FAERS
23Acute Coronary SyndromeFAERS: 1US FAERS
24AlveolitisFAERS: 1US FAERS
25Bleeding time abnormalFAERS: 1US FAERS
26Blood count abnormalFAERS: 1US FAERS
27Blood creatinine increasedFAERS: 1US FAERS
28Bowel movement irregularityFAERS: 1US FAERS
29Brain natriuretic peptide increasedFAERS: 1US FAERS
30Disease ProgressionFAERS: 1US FAERS
31DizzinessFAERS: 1US FAERS
32DysgeusiaFAERS: 1US FAERS
33DysphoniaFAERS: 1US FAERS
34EosinophiliaFAERS: 1US FAERS
35Eye InfectionFAERS: 1US FAERS
36Flank PainFAERS: 1US FAERS
37General physical health deteriorationFAERS: 1US FAERS
38HemiplegiaFAERS: 1OFFSIDES
US FAERS
39Hepatic congestionFAERS: 1US FAERS
40HepatitisFAERS: 117160201CTD
US FAERS
41HysterectomyFAERS: 1US FAERS
42Kidney congestionFAERS: 1US FAERS
43LeukoencephalopathyFAERS: 1OFFSIDES
US FAERS
44Living in residential institutionFAERS: 1US FAERS
45LymphadenopathyFAERS: 1US FAERS
46MicrocytosisFAERS: 1US FAERS
47NervousnessFAERS: 1US FAERS
48PainFAERS: 1US FAERS
49PallorFAERS: 1US FAERS
50PetechiaeFAERS: 1US FAERS
51Platelet function test abnormalFAERS: 1US FAERS
52PneumoniaFAERS: 1US FAERS
53PolyneuropathyFAERS: 1US FAERS
54Postoperative thrombosisFAERS: 1US FAERS
55Product compounding quality issueFAERS: 1US FAERS
56Product dose omissionFAERS: 1US FAERS
57Product use issueFAERS: 1US FAERS
58Pseudobulbar PalsyFAERS: 1US FAERS
59Pulmonary congestionFAERS: 1US FAERS
60SarcomaFAERS: 1US FAERS
61Skin reactionFAERS: 1US FAERS
62Skin test positiveFAERS: 1US FAERS
63Subcutaneous AbscessFAERS: 1US FAERS
64Supraventricular tachycardiaFAERS: 1OFFSIDES
US FAERS
65Tongue bitingFAERS: 1OFFSIDES
US FAERS
66ToxoplasmosisFAERS: 1

View details

4137833
5106499
8228015
8773165
9043986
15909603
 		CTD
OFFSIDES
US FAERS
67TremorFAERS: 1US FAERS
68Unevaluable eventFAERS: 1US FAERS
69Urinary tract infectionFAERS: 1US FAERS
70Ventricular FibrillationFAERS: 1OFFSIDES
US FAERS
71colonoscopyFAERS: 1US FAERS
72treatment failureFAERS: 1US FAERS
73Abnormal visionOFFSIDES
74Acute kidney injury8773165CTD
75Agranulocytosis7162443CTD
76Anaphylactic shockSIDER
77Anemia, Hemolytic1124444
4852166		CTD
78Anemia, Macrocytic6518642CTD
79Anemia, Megaloblastic

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63088
828128
1256293
3628888
5141843
7280928
7741386
 		CTD
80AnisocoriaOFFSIDES
81AnorexiaSIDER
82AnuriaOFFSIDES
83AstheniaOFFSIDES
84AtaxiaOFFSIDES
85Autoimmune Lymphoproliferative Syndrome17674358CTD
86Blood cholesterolOFFSIDES
87Blood creatine phosphokinase increasedOFFSIDES
88Blood magnesium decreasedOFFSIDES
89Blood potassium decreasedOFFSIDES
90Bone Marrow Diseases4137833
5771778		CTD
91Brain Diseases8228015CTD
92Cardioactive drug levelOFFSIDES
93Ciliophora Infections12113305CTD
94Cytolytic hepatitisOFFSIDES
95Cytomegalovirus chorioretinitisOFFSIDES
96Demyelinating Diseases267250CTD
97Depressed Level of ConsciousnessOFFSIDES
98Disseminated Intravascular Coagulation1124444CTD
OFFSIDES
99Drug Overdose8785570CTD
100Encephalitis8773165CTD
101Erythema MultiformeSIDER
102Fish Diseases12113305CTD
103FlatulenceOFFSIDES
104GangreneOFFSIDES
105Genital erosionOFFSIDES
106Gliosis267250CTD
107Granulocytes maturation arrestOFFSIDES
108Hematoma2859662CTD
109Hemoglobinuria4852166CTD
110Hemorrhage2859662CTD
111HydrocephalusOFFSIDES
112HyperpigmentationOFFSIDES
113HypertransaminasaemiaOFFSIDES
114Intraocular inflammationOFFSIDES
115Kidney Calculi8773165CTD
116Kidney FailureOFFSIDES
117Leukoencephalitis, Acute Hemorrhagic17907889CTD
118Leukopenia neonatalOFFSIDES
119LeukopeniaSIDER
120Limb Deformities, Congenital2859662CTD
121Lip erosionOFFSIDES
122LipaseOFFSIDES
123Lymphocyte count decreasedOFFSIDES
124Malaria, Falciparum

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4885738
4922770
10837185
11579891
11675058
 		CTD
125Malaria

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1124444
4776885
17160201
20193682
 		CTD
OFFSIDES
126Melanoma, Experimental18593930CTD
127Mental status changesOFFSIDES
128MicrolithiasisOFFSIDES
129Molluscum ContagiosumOFFSIDES
130Muscle WeaknessOFFSIDES
131Myocarditis17160201CTD
132MyoglobinaemiaOFFSIDES
133Necrosis267250CTD
134Nephrogenic Diabetes InsipidusOFFSIDES
135Nerve Degeneration267250CTD
136Optic Disc EdemaOFFSIDES
137OsteoporosisOFFSIDES
138PancreatitisOFFSIDES
139Pancytopenia828128
5106499		CTD
SIDER
140ParaparesisOFFSIDES
141Plasmodium falciparum infectionOFFSIDES
142Postrenal failureOFFSIDES
143Productive CoughOFFSIDES
144Pseudomonal sepsisOFFSIDES
145Pulmonary EosinophiliaSIDER
146SchistosomiasisOFFSIDES
147Seizures3139186
7875556
8785570		CTD
148Septic ShockOFFSIDES
149Serositis17160201CTD
150Stevens-Johnson Syndrome25811541CTD
OFFSIDES
SIDER
151Thoracic vertebral fractureOFFSIDES
152Thyroiditis17160201CTD
153Toxic Epidermal NecrolysisSIDER
154Toxoplasmosis, Cerebral

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1863412
2385768
3400670
7741386
8243240
8272240
8463770
16732870
 		CTD
155Unresponsive to stimuliOFFSIDES
156Weight GainOFFSIDES
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