MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Fat necrosis

(UMLS:C0015668)

Definition:: A condition in which the death of adipose tissue results in neutral fats being split into fatty acids and glycerol.
UMLS ID:: C0015668
MeSH ID:: D005218

Classification:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.717.365

Synonym(s)

Fat necrosis

Cystosteatonecrosis

Cytosteatonecrosis

Fat Necrosis

Necrosis, fat

Necrosis;fat

Steatonecrosis

fat necrosis

fat; necrosis

10.

fatty necrosis

11.

necrosis; fat

12.

steatonecrosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Diclofenac	FAERS: 6		US FAERS
2	Glatiramer Acetate	FAERS: 4		US FAERS
3	Octreotide	FAERS: 4		US FAERS
4	Risperidone	FAERS: 4		US FAERS
5	Triamcinolone Acetonide	FAERS: 4		US FAERS
6	Alendronate	FAERS: 3		US FAERS
7	Carbamazepine	FAERS: 3		US FAERS
8	Medroxyprogesterone Acetate	FAERS: 3		US FAERS
9	Mitomycin	FAERS: 3		OFFSIDES US FAERS
10	Sitagliptin Phosphate	FAERS: 3		US FAERS
11	Warfarin	FAERS: 3		US FAERS
12	Alprostadil	FAERS: 2		US FAERS
13	Arthrotec	FAERS: 2		US FAERS
14	Carboplatin	FAERS: 2		US FAERS
15	Ciprofloxacin	FAERS: 2		US FAERS
16	Exenatide	FAERS: 2		US FAERS
17	Hydroxyzine	FAERS: 2		US FAERS
18	Hydroxyzine	FAERS: 2		US FAERS
19	Isotretinoin	FAERS: 2		US FAERS
20	Zoledronic Acid	FAERS: 2		OFFSIDES US FAERS
21	dexamethasone 21-phosphate	FAERS: 2		US FAERS
22	reviparin	FAERS: 2		US FAERS
23	sibutramine	FAERS: 2		US FAERS
24	Atorvastatin	FAERS: 1		US FAERS
25	Azacitidine	FAERS: 1		US FAERS
26	Baclofen	FAERS: 1		US FAERS
27	Betamethasone	FAERS: 1		US FAERS
28	Bortezomib	FAERS: 1		OFFSIDES US FAERS
29	Cyclosporine	FAERS: 1		US FAERS
30	Deoxycholic Acid	FAERS: 1		US FAERS
31	Dipyrone	FAERS: 1		US FAERS
32	Epinephrine	FAERS: 1		US FAERS
33	Lenalidomide	FAERS: 1		US FAERS
34	PCI 32765	FAERS: 1		US FAERS
35	Paliperidone Palmitate	FAERS: 1		US FAERS
36	Sevelamer	FAERS: 1		OFFSIDES US FAERS
37	Tamoxifen	FAERS: 1		US FAERS
38	Vemurafenib	FAERS: 1		US FAERS
39	apremilast	FAERS: 1		US FAERS
40	etonogestrel	FAERS: 1		US FAERS
41	gemcitabine	FAERS: 1		US FAERS
42	lanreotide	FAERS: 1		US FAERS
43	paricalcitol	FAERS: 1		OFFSIDES US FAERS
44	pazopanib	FAERS: 1		US FAERS
45	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride			OFFSIDES
46	Acetaminophen			OFFSIDES
47	Amisulpride			OFFSIDES
48	Amoxicillin			OFFSIDES
49	Azithromycin			OFFSIDES
50	Buspirone			OFFSIDES
51	Calcium Compounds			OFFSIDES
52	Chlorhexidine			OFFSIDES
53	Docetaxel			OFFSIDES
54	Dronabinol			OFFSIDES
55	Erlotinib Hydrochloride			OFFSIDES
56	Estradiol			OFFSIDES
57	Etodolac			OFFSIDES
58	Fludrocortisone			OFFSIDES
59	Fluticasone-Salmeterol Drug Combination			OFFSIDES
60	Formoterol Fumarate			OFFSIDES
61	Fulvestrant			OFFSIDES
62	Ganciclovir			OFFSIDES
63	Gentamicins			SIDER
64	Granisetron			OFFSIDES
65	Indomethacin			OFFSIDES
66	Ketorolac Tromethamine			OFFSIDES
67	Methylene			SIDER
68	Methylprednisolone Acetate			OFFSIDES
69	Metolazone			OFFSIDES
70	Nortriptyline			OFFSIDES
71	NuvaRing			OFFSIDES
72	Octreotide			OFFSIDES
73	Orphenadrine			OFFSIDES
74	Palonosetron			OFFSIDES
75	Pamidronate			OFFSIDES
76	Paraldehyde			SIDER
77	Penicillin V			OFFSIDES
78	Phenprocoumon			OFFSIDES
79	Phentermine			OFFSIDES
80	Pioglitazone			OFFSIDES
81	Prochlorperazine			OFFSIDES
82	Progesterone			OFFSIDES
83	Quetiapine Fumarate			OFFSIDES
84	Spironolactone			OFFSIDES
85	Sulfamethoxazole			OFFSIDES
86	Tamoxifen			OFFSIDES
87	Tetracycline			OFFSIDES
88	Thioacetamide		16456712	CTD
89	Vinorelbine			OFFSIDES
90	Vitamin B 12			OFFSIDES
91	calcium acetate			OFFSIDES
92	cefuroxime axetil			OFFSIDES
93	chlorhexidine gluconate			OFFSIDES
94	gemcitabine			OFFSIDES
95	hydrocortisone-17-butyrate			OFFSIDES
96	rofecoxib			OFFSIDES
97	tegaserod			OFFSIDES
98	tizanidine			OFFSIDES
99	valdecoxib			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Gangrene	46.7%
2	Infarction	44.4%
3	Aseptic Necrosis of Bone	31.8%
4	Dental Pulp Necrosis	31.1%
5	Ascites	31%
6	Fibrosis	31%
7	Gliosis	31%
8	Growth Disorders	31%
9	Hemorrhage	31%
10	Hyperbilirubinemia	31%
11	Hyperplasia	31%
12	Hypomenorrhea	31%
13	Inflammation	31%
14	Intraoperative Complications	31%
15	Ischemia	31%
16	Lithiasis	31%
17	Malacoplakia	31%
18	Menstruation Disturbances	31%
19	Metaplasia	31%
20	Nerve Degeneration	31%
21	Ochronosis	31%
22	Polymenorrhea	31%
23	Postoperative Complications	31%
24	Sclerosis	31%
25	Shock	31%
26	Ulcer	31%
27	Hyperammonemia	31%
28	Hyperamylasemia	31%
29	Teratogenesis	31%
30	Cardiac Death	31%
31	Hypovolemia	31%
32	Hyperuricemia	31%
33	Leukoaraiosis	31%
34	Dysbacteriosis	31%
35	Delayed Graft Function	31%
36	Cirrhosis	31%
37	Neointima	31%
38	Dysbiosis	31%
39	Polydipsia	27.9%
40	Postoperative Hemorrhage	26.7%
41	Shock, Hemorrhagic	26.7%
42	Systemic Inflammatory Response Syndrome	26.7%
43	DNA Degradation, Necrotic	23.7%
44	Femur Head Necrosis	23.1%
45	Extravasation of Diagnostic and Therapeutic Materials	22%
46	Neoplastic Processes	22%
47	Vascular Remodeling	21.1%
48	Granulomatosis, Orofacial	20.9%
49	Pigmentation Disorders	20.9%
50	Respiratory Aspiration	20.9%
51	Acantholysis	20.5%
52	Chromosome Aberrations	20.5%
53	Dehydration	20.5%
54	Granuloma	20.5%
55	Leukocytosis	20.5%
56	Pleocytosis	20.5%
57	Acute Disease	20%
58	Acute-Phase Reaction	20%
59	Amenorrhea	20%
60	Chronic disease	20%
61	Critical Illness	20%
62	Sudden death	20%
63	Graft Occlusion, Vascular	20%
64	Granuloma, Plasma Cell	20%
65	Hematoma	20%
66	Iatrogenic Disease	20%
67	Multiple Organ Failure	20%
68	Oligomenorrhea	20%
69	Premenstrual syndrome	20%
70	Recurrence	20%
71	Retrograde Degeneration	20%
72	Retroperitoneal fibrosis	20%
73	Serositis	20%
74	Subcutaneous Emphysema	20%
75	Surgical Wound Dehiscence	20%
76	Syndrome	20%
77	Wallerian Degeneration	20%
78	Pyogenic granuloma	20%
79	Exsanguination	20%
80	Disease Progression	20%
81	Seroma	20%
82	Premenstrual Tension	20%
83	Delayed Emergence from Anesthesia	20%
84	Infant Death	20%
85	Anastomotic Leak	20%
86	Intraoperative Awareness	20%
87	Sudden infant death syndrome	19.6%
88	Signs and Symptoms	18.5%
89	Pathological Conditions, Anatomical	18.5%
90	Incisional hernia	17.8%
91	jaundice	17.8%
92	Menorrhagia	17.1%
93	Pain, Postoperative	16.5%
94	Chromosomal Instability	16.1%
95	Genomic Instability	16.1%
96	Dysmenorrhea	15.8%
97	Failed Back Surgery Syndrome	15.8%
98	Azotemia	14.9%
99	Tissue Adhesions	14.8%
100	Postoperative Nausea and Vomiting	14.8%
101	Hematoma, Epidural, Spinal	14.8%
102	Asphyxia	14.3%
103	Granuloma, Respiratory Tract	14.3%
104	Shock, Traumatic	14.3%
105	Muscle Weakness	14.3%
106	Eye Hemorrhage	14%
107	Disease susceptibility	13.6%
108	Fetal Death	13.6%
109	Foreign-Body Reaction	13.6%
110	Gastrointestinal Hemorrhage	13.6%
111	Hemarthrosis	13.6%
112	Hemoperitoneum	13.6%
113	Hemothorax	13.6%
114	Neoplasm Invasiveness	13.6%
115	Neoplasm Metastasis	13.6%
116	Neoplasm Recurrence, Local	13.6%
117	Postpericardiotomy Syndrome	13.6%
118	Prosthesis Failure	13.6%
119	Reperfusion Injury	13.6%
120	Injection Site Reaction	13.6%
121	Retrobulbar Hemorrhage	13.6%
122	Peritoneal Fibrosis	13.6%
123	Carcinogenesis	13.6%
124	Neurogenic Inflammation	13.6%
125	Perinatal death	13.6%
126	Infusion site reaction	13.6%
127	Nephrogenic Fibrosing Dermopathy	13.6%
128	Corneal Endothelial Cell Loss	13.6%
129	Encapsulating Peritoneal Sclerosis	13.6%
130	Vasoplegia	13.6%
131	Suppuration	13.6%
132	Nephrogenic Systemic Fibrosis	13.6%
133	Metastasis	13.6%
134	Hemoptysis	13.6%
135	Endotoxic shock	13.5%
136	Septic Shock	13.5%
137	Toxic Shock Syndrome	13.5%
138	Sinus Arrhythmia	13.3%
139	Atrial Fibrillation	13.3%
140	Atrial Flutter	13.3%
141	Ecchymosis	13.3%
142	Granuloma, Foreign-Body	13.3%
143	Mediastinal Emphysema	13.3%
144	Petechiae	13.3%
145	Purpura	13.3%
146	Surgical Wound Infection	13.3%
147	Ventricular Fibrillation	13.3%
148	Ventricular Flutter	13.3%
149	Parasystole	13.3%
150	Paroxysmal atrial fibrillation	13.3%
151	Facies	13.3%
152	Bradycardia	13.3%
153	Embryo Loss	13.3%
154	Afferent Loop Syndrome	13.2%
155	Sex Chromosome Aberrations	13.2%
156	Short Bowel Syndrome	13.2%
157	Uterine hemorrhage	13.2%
158	No-Reflow Phenomenon	13.2%
159	Jaundice, Obstructive	13%
160	Cardiotoxicity	12.4%
161	Hematoma, Subdural, Spinal	12.2%
162	Chromosome Fragility	11.7%
163	Epistaxis	11%
164	Drowning	10.5%
165	Asthenia	10.3%
166	Body Temperature Changes	10.3%
167	Calculi	10.3%
168	Cyanosis	10.3%
169	Edema	10.3%
170	Failure to Thrive	10.3%
171	Fatigue	10.3%
172	Feminization	10.3%
173	Fetal Distress	10.3%
174	Hernia	10.3%
175	Hypertrophy	10.3%
176	Motion Sickness	10.3%
177	Nails, Malformed	10.3%
178	polyps	10.3%
179	Rupture, Spontaneous	10.3%
180	Signs and Symptoms, Digestive	10.3%
181	Signs and Symptoms, Respiratory	10.3%
182	Skin Manifestations	10.3%
183	Chills	10.3%
184	Lassitude	10.3%
185	Enterocele	10.3%
186	Atheroma	10.3%
187	Pseudophakia	10.3%
188	Urological Manifestations	10.3%
189	Stenosis	10.3%
190	Facial asymmetry	10.3%
191	Mobility Limitation	10.3%
192	Somnolence	10.3%
193	Plaque, Amyloid	10.3%
194	Plaque, Atherosclerotic	10.3%
195	Fetal Growth Retardation	10.2%
196	Cross Infection	10.1%
197	Hyphema	10.1%
198	Retinal Neovascularization	10.1%
199	Septicemia	10.1%
200	Vitreous Hemorrhage	10.1%
201	Sepsis	10.1%
202	Aneuploidy	10.1%
203	Polyploidy	10.1%
204	Microsatellite Instability	10.1%
205	Heart Block	10%
206	Tachycardia	10%
207	Tachyarrhythmia	10%
208	Cicatrix	10%
209	Hematuria	9.9%
210	Granuloma Annulare	9.9%
211	Chromosome Breakage	9.9%
212	Abscess	9.9%
213	Empyema	9.9%
214	Fetal Resorption	9.9%
215	Lymphatic Metastasis	9.9%
216	Neoplasms, Unknown Primary	9.9%
217	Peptic Ulcer Hemorrhage	9.9%
218	Sudden Cardiac Death	9.9%
219	Leukemic Infiltration	9.9%
220	Premenstrual Dysphoric Disorder	9.9%
221	Choroidal Neovascularization	9.9%
222	Primary Graft Dysfunction	9.9%
223	Neoplasm Micrometastasis	9.9%
224	Brain Death	9.9%
225	Hematemesis	9.8%
226	Shock, Cardiogenic	9.8%
227	Dumping Syndrome	9.8%
228	Cicatrix, Hypertrophic	9.8%
229	Sinus Arrest, Cardiac	9.8%
230	Purpura Fulminans	9.8%
231	Metrorrhagia	9.7%
232	Sick Sinus Syndrome	9.7%
233	Trisomy	9.7%
234	Viremia	8.8%
235	Parasitemia	8.8%
236	Hematoma, Subdural	8.3%
237	Hematoma, Epidural, Cranial	8.3%
238	Giant Cell Epulis	8.2%
239	Long QT Syndrome	7.9%
240	Micronuclei, Chromosome-Defective	7.8%
241	Abdominal Pain	7.7%
242	Retinal Hemorrhage	7.7%
243	Phantom pain	7.6%
244	Phantom Limb Pain	7.6%
245	Choroid Hemorrhage	7.6%
246	Melena	7.6%
247	Postpartum Hemorrhage	7.4%
248	Gingival Hemorrhage	7.4%
249	Keloid	7.4%
250	Monosomy	7.3%
251	Tetraploidy	7.3%
252	Stillbirth	7.3%
253	Adams-Stokes Syndrome	7.3%
254	Atrioventricular Block	7.3%
255	Bundle-Branch Block	7.3%
256	Cyst	7.3%
257	Eye Manifestations	7.3%
258	Neurologic Manifestations	7.3%
259	Atrial Premature Complexes	7.3%
260	Sinoatrial Block	7.3%
261	Tachycardia, Paroxysmal	7.3%
262	Supraventricular tachycardia	7.3%
263	Tachycardia, Ventricular	7.3%
264	Tachycardia, Reciprocating	7.3%
265	Subarachnoid Hemorrhage	7.3%
266	Cerebral Hemorrhage	7.3%
267	Leukoplakia	7%
268	Cardiac Output, High	7%
269	Myocardial Stunning	7%
270	Reticulocytosis	7%
271	Low Cardiac Output Syndrome	7%
272	Airway Remodeling	7%
273	Hematoma, Subdural, Intracranial	6.8%
274	Hematoma, Subdural, Chronic	6.8%
275	Hematoma, Subdural, Acute	6.8%
276	Ventricular Remodeling	6.8%
277	Subacute Combined Degeneration	6.7%
278	Alopecia	6.7%
279	Intermittent Claudication	6.7%
280	Androgenetic Alopecia	6.7%
281	Thrombocytopenic purpura	6.7%
282	Anorexia	6.7%
283	Anoxia	6.7%
284	Constipation	6.7%
285	Diarrhea	6.7%
286	Dyspepsia	6.7%
287	Eructation	6.7%
288	Fever	6.7%
289	Flatulence	6.7%
290	Flushing	6.7%
291	Halitosis	6.7%
292	Heartburn	6.7%
293	Diaphragmatic Hernia	6.7%
294	Hiccough	6.7%
295	Hypercalciuria	6.7%
296	Hypercapnia	6.7%
297	Hyperphagia	6.7%
298	Intestinal Polyps	6.7%
299	Nausea	6.7%
300	Pallor	6.7%
301	Psychophysiologic Disorders	6.7%
302	Splenomegaly	6.7%
303	Vomiting	6.7%
304	Hypocapnia	6.7%
305	Dyschezia	6.7%
306	Hypoxia	6.7%
307	Hyperoxia	6.7%
308	Lower Urinary Tract Symptoms	6.7%
309	Hypoxemia	6.7%
310	Urinoma	6.7%
311	Eosinophilic Granuloma	6.6%
312	Purpura, Hyperglobulinemic	6.5%
313	Bacteremia	6.3%
314	Cell Transformation, Viral	6.2%
315	Fungemia	6.2%
316	Cellulitis	6%
317	Tachycardia, Atrioventricular Nodal Reentry	6%
318	Tachycardia, Ectopic Atrial	6%
319	Tachycardia, Ectopic Junctional	6%
320	Sinus Tachycardia	6%
321	Torsades de Pointes	6%
322	Accelerated Idioventricular Rhythm	6%
323	Renal Colic	6%
324	Abdomen, Acute	5.9%
325	Eye pain	5.9%
326	Romano-Ward Syndrome	5.8%
327	Muscular Atrophy	5.8%
328	Kernicterus	5.7%
329	Endotoxemia	5.5%
330	Purpura, Thrombotic Thrombocytopenic	5.4%
331	Hypergammaglobulinemia	5.2%
332	Granuloma, Laryngeal	5.1%
333	Diverticulum	5%
334	Diverticulosis	5%
335	Myocardial Reperfusion Injury	5%
336	Back Pain	4.9%
337	Bulimia	4.9%
338	Neck Pain	4.9%
339	Chest Pain	4.9%
340	Colonic Polyps	4.9%
341	Dizziness	4.9%
342	Dysuria	4.9%
343	Facial Pain	4.9%
344	Fever of Unknown Origin	4.9%
345	Flank Pain	4.9%
346	Headache	4.9%
347	Nocturia	4.9%
348	Pain, Intractable	4.9%
349	Pelvic Pain	4.9%
350	Snoring	4.9%
351	Chronic pain	4.9%
352	Lightheadedness	4.9%
353	Pain, Referred	4.9%
354	Prostatism	4.9%
355	Throbbing Headache	4.9%
356	Labor Pain	4.9%
357	Cancer Pain	4.9%
358	Nociceptive Pain	4.9%
359	Respiratory Tract Fistula	4.8%
360	Apnea	4.5%
361	Cheyne-Stokes Respiration	4.5%
362	Decerebrate State	4.5%
363	Dyspnea	4.5%
364	Cardiomegaly	4.5%
365	Hemiparesis	4.5%
366	Hepatomegaly	4.5%
367	Hyperventilation	4.5%
368	Meningism	4.5%
369	Mouth Breathing	4.5%
370	Paresis	4.5%
371	Parovarian Cyst	4.5%
372	Pruritus	4.5%
373	Seizures	4.5%
374	Sensation Disorders	4.5%
375	Sneezing	4.5%
376	Spermatocele	4.5%
377	Erythema	4.5%
378	Oral Fistula	4.5%
379	Complex partial seizures	4.5%
380	Necrolytic Migratory Erythema	4.5%
381	Tachypnea	4.5%
382	Monoparesis	4.5%
383	Cutaneous Fistula	4.5%
384	Gait Disorders, Neurologic	4.5%
385	Neuromuscular Manifestations	4.5%
386	Cardiac Hypertrophy	4.5%
387	Sarcopenia	4.5%
388	Edema, Cardiac	4.4%
389	Mental Fatigue	4.4%
390	Hirsutism	4.4%
391	Orthostatic intolerance	4.4%
392	Hypoventilation	4.4%
393	Vaginal Fistula	4.4%
394	Rectocele	4.4%
395	Body Weight Changes	4.4%
396	Autoimmune thrombocytopenia	4.1%
397	Immune thrombocytopenic purpura	4.1%
398	Philadelphia Chromosome	4.1%
399	Emaciation	4.1%
400	Low Back Pain	4.1%
401	Visceral Pain	4.1%
402	Waterhouse-Friderichsen Syndrome	3.9%
403	Sleep Wake Disorders	3.7%
404	Cachexia	3.6%
405	Candidemia	3.6%
406	Gait Ataxia	3.6%
407	Pupil Disorders	3.6%
408	Neurobehavioral Manifestations	3.6%
409	Nasal Polyps	3.4%
410	Basal Ganglia Hemorrhage	3.4%
411	Pleural Rub	3.4%
412	Rales	3.4%
413	Respiratory Sounds	3.4%
414	Rhonchi	3.4%
415	Stridor	3.4%
416	Wheezing	3.4%
417	Asterixis	3.4%
418	Ballismus	3.4%
419	Biliary Fistula	3.4%
420	Gastric Fistula	3.4%
421	Congenital diaphragmatic hernia	3.4%
422	Morning Sickness	3.4%
423	Vertigo	3.4%
424	Hoarseness	3.3%
425	Pain	3.3%
426	Livedo Reticularis	3.3%
427	Ache	3.3%
428	Meningocele	3.3%
429	Oliguria	3.3%
430	Polyuria	3.3%
431	Proteinuria	3.3%
432	Urinary Calculi	3.3%
433	Encephalocele	3.3%
434	Anosmia	3.3%
435	Ataxia	3.3%
436	Athetosis	3.3%
437	Catalepsy	3.3%
438	Dental Fistula	3.3%
439	Dystonia	3.3%
440	Hemiplegia	3.3%
441	Locked-In Syndrome	3.3%
442	Muscle Hypertonia	3.3%
443	Muscle hypotonia	3.3%
444	Myoclonus	3.3%
445	Myotonia	3.3%
446	Neuralgia	3.3%
447	Oroantral Fistula	3.3%
448	Paraplegia	3.3%
449	Pseudobulbar Palsy	3.3%
450	Quadriplegia	3.3%
451	Spasm	3.3%
452	Spastic Paraplegia	3.3%
453	Status Epilepticus	3.3%
454	Taste Disorders	3.3%
455	Tremor	3.3%
456	Monoplegia	3.3%
457	Hypokinesia	3.3%
458	Left Ventricular Hypertrophy	3.3%
459	Gastroparesis	3.3%
460	Right Ventricular Hypertrophy	3.3%
461	Paraparesis	3.3%
462	Bradykinesia	3.3%
463	Waxy flexibility	3.3%
464	Action Tremor	3.3%
465	Resting Tremor	3.3%
466	Dysosmia	3.3%
467	Quadriparesis	3.3%
468	Olfaction Disorders	3.3%
469	Myokymia	3.3%
470	Somatosensory Disorders	3.3%
471	Neuropathic pain	3.3%
472	Hyperkinesia	3.3%
473	Intention tremor	3.3%
474	Body Weight	3.3%
475	Rectal Prolapse	3.3%
476	Uterine Prolapse	3.3%
477	Vaginal Prolapse	3.3%
478	Underweight	3.2%
479	Overweight	3.2%
480	Weight Gain	3.2%
481	Putaminal Hemorrhage	3.1%
482	Akathisia	3%
483	Restlessness	3%
484	Psychomotor Agitation	3%
485	Vesicovaginal Fistula	2.9%
486	Gait Apraxia	2.8%
487	Umbilical hernia	2.8%
488	Toothache	2.8%
489	Voice Disorders	2.8%
490	Voice Disturbance	2.8%
491	Hyperemesis Gravidarum	2.7%
492	Dysgeusia	2.7%
493	Formication	2.7%
494	Gagging	2.7%
495	Hyperalgesia	2.7%
496	Hyperesthesia	2.7%
497	Hypesthesia	2.7%
498	Language Disorders	2.7%
499	Numbness	2.7%
500	Paresthesia	2.7%
501	Paraparesis, Spastic	2.7%
502	Trismus	2.7%
503	Epilepsia Partialis Continua	2.7%
504	Hypogeusia	2.7%
505	Brown-Sequard Syndrome	2.7%
506	Lockjaw	2.7%
507	Allodynia	2.7%
508	Ageusia	2.7%
509	Leukoplakia, Oral	2.6%
510	Vision Disorders	2.6%
511	Metamorphopsia	2.6%
512	Visual Impairment	2.6%
513	Bronchial Fistula	2.6%
514	Metatarsalgia	2.6%
515	Pancreatic Fistula	2.6%
516	Anisocoria	2.5%
517	Confusion	2.5%
518	Facial paralysis	2.5%
519	Intestinal Fistula	2.5%
520	Lethargy	2.5%
521	Memory Disorders	2.5%
522	Muscle Cramp	2.5%
523	Perceptual Disorders	2.5%
524	Psychomotor Disorders	2.5%
525	Tonic Pupil	2.5%
526	Anhedonia	2.5%
527	Disorientation	2.5%
528	Gastroschisis	2.5%
529	Enterocutaneous Fistula	2.5%
530	Fetal Hypoxia	2.5%
531	Facial Paresis	2.5%
532	Memory Loss	2.5%
533	Hemisensory Neglect	2.5%
534	Dysacusis	2.5%
535	Dyspnea, Paroxysmal	2.5%
536	Mastodynia	2.5%
537	Respiratory Paralysis	2.5%
538	Salivary Gland Fistula	2.5%
539	Chorea	2.5%
540	Cystocele	2.5%
541	Tetany	2.5%
542	Urinary Incontinence	2.5%
543	Breakthrough Pain	2.5%
544	Albuminuria	2.4%
545	Hemoglobinuria	2.4%
546	Agraphia	2.4%
547	Alexia	2.4%
548	Anomia	2.4%
549	Cluttering	2.4%
550	Language Development Disorders	2.4%
551	Speech Disorders	2.4%
552	Syncope	2.4%
553	Stupor	2.4%
554	Dysgraphia	2.4%
555	Dyslexia	2.4%
556	Presyncope	2.4%
557	Dyslalia	2.4%
558	Alice in Wonderland Syndrome	2.3%
559	Aphasia	2.3%
560	Articulation Disorders	2.3%
561	Echolalia	2.3%
562	Stuttering	2.3%
563	Dysphasia	2.3%
564	Jet Lag Syndrome	2.2%
565	Reflex, Abnormal	2.2%
566	Hyporeflexia	2.2%
567	Hyperreflexia	2.2%
568	Dysarthria	2.2%
569	Birth Weight	2.1%
570	Diplopia	2.1%
571	Muscle Rigidity	2.1%
572	Muscle Spasticity	2.1%
573	Scotoma	2.1%
574	Photophobia	2.1%
575	Cogwheel Rigidity	2.1%
576	Hemifacial Spasm	2.1%
577	Amaurosis	2.1%
578	Blindness	2.1%
579	Nuchal Rigidity	2.1%
580	Angina Pectoris	2.1%
581	Agnosia	2%
582	Apraxias	2%
583	Consciousness Disorders	2%
584	Hallucinations	2%
585	Hemianopsia	2%
586	Mental Retardation	2%
587	Hyperacusis	2%
588	Tinnitus	2%
589	Visual Agnosia	2%
590	Anosognosia	2%
591	Wernicke-Korsakoff Syndrome	2%
592	Depressed Level of Consciousness	2%
593	Phonophobia	2%
594	Mental deficiency	2%
595	Intellectual Disability	2%
596	Hearing Loss	2%
597	Cerebellar Ataxia	2%
598	Torticollis	2%
599	Sciatica	2%
600	Urge Incontinence	2%
601	Tardive Dyskinesia	2%
602	Catatonia	2%
603	Musculoskeletal Pain	2%
604	Ophthalmoplegia	2%
605	External Ophthalmoplegia	2%
606	Aphonia	2%
607	Arthralgia	2%
608	Sleep Deprivation	2%
609	Polyarthralgia	2%
610	Dysphonia	2%
611	Cerebrospinal Fluid Otorrhea	2%
612	Cerebrospinal Fluid Rhinorrhea	2%
613	Obesity	1.9%
614	Amaurosis Fugax	1.8%
615	Blindness, Cortical	1.8%
616	Dyscalculia	1.8%
617	Angina, Unstable	1.8%
618	Deafness	1.8%
619	Hearing Loss, Sudden	1.8%
620	Gerstmann Syndrome	1.8%
621	Hearing Loss, Bilateral	1.8%
622	Hearing Loss, High-Frequency	1.8%
623	Hearing Loss, Mixed Conductive-Sensorineural	1.8%
624	Prosopagnosia	1.8%
625	Apraxia, Ideomotor	1.8%
626	Persistent Vegetative State	1.8%
627	Charles Bonnet Syndrome	1.8%
628	Hearing Loss, Unilateral	1.8%
629	Complete Hearing Loss	1.8%
630	Alien Hand Syndrome	1.8%
631	Deaf Mutism	1.8%
632	Mutism	1.7%
633	Selective Mutism	1.7%
634	Angina Pectoris, Variant	1.7%
635	Vocal Cord Paralysis	1.7%
636	Alexia, Pure	1.7%
637	Amblyopia	1.7%
638	Amnesia	1.7%
639	Delirium	1.7%
640	Horner Syndrome	1.7%
641	Dissociative Amnesia	1.7%
642	Color blindness	1.7%
643	Global Amnesia	1.7%
644	Hydrops Fetalis	1.7%
645	Urinary Bladder Fistula	1.6%
646	Rectal Fistula	1.6%
647	Anal Fistula	1.6%
648	Fetal Weight	1.6%
649	Shoulder Pain	1.6%
650	Tinea Pedis	1.6%
651	Pediatric Obesity	1.6%
652	Retrograde amnesia	1.5%
653	Amnesia, Anterograde	1.5%
654	Dyskinesia, Drug-Induced	1.4%
655	Akathisia, Drug-Induced	1.4%
656	Alcohol Withdrawal Seizures	1.4%
657	Arteriovenous fistula	1.4%
658	Myalgia	1.4%
659	Amnesia, Transient Global	1.2%
660	Kidney Calculi	1.2%
661	Ureteral Calculi	1.2%
662	Auditory Perceptual Disorders	1.2%
663	Ophthalmoplegic Migraine	1%
664	Progressive supranuclear palsy	1%
665	Kearns-Sayre syndrome	0.7%

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