MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Genomic Instability

(UMLS:C0919532)

Definition:: An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.
UMLS ID:: C0919532
MeSH ID:: D042822

Classification 1:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.362

Classification 2:

Name:

Genetic Phenomena
MeSH Tree Number(s):: G05.365.590.335|G05.370

Synonym(s)

Genomic Instability

genome instability

genomes instability

Associated Drug(s)

	Name	Reference(s)	Data Source
1	1,3-butadiene	21602187	CTD
2	9,10-Dimethyl-1,2-benzanthracene	21527772	CTD
3	Aflatoxin B1	21527772	CTD
4	Calcium Hydroxide	30615914	CTD
5	Carbon Tetrachloride	26778414	CTD
6	Cyclophosphamide	21527772	CTD
7	Dactinomycin	21527772	CTD
8	Diethylnitrosamine	21527772 26778414	CTD
9	Etoposide	21527772	CTD
10	Methyl Methanesulfonate	21527772	CTD
11	Methylnitronitrosoguanidine	20869957	CTD
12	Mitomycin	28077981	CTD
13	O-(6)-methylguanine	29616805	CTD
14	chlorpyrifos-ethyl	26198043	CTD
15	methyleugenol	28326452	CTD
16	ochratoxin A	21551354 21622941	CTD
17	sodium arsenite	27908234	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Chromosome Aberrations	44.3%
2	Trisomy	40.5%
3	Aneuploidy	38.6%
4	Polyploidy	38.6%
5	Chromosome Breakage	35.8%
6	Sex Chromosome Aberrations	33.6%
7	Monosomy	31.5%
8	Tetraploidy	31.5%
9	Genetic Polymorphism	27.3%
10	Chromosomal Instability	26.9%
11	Mosaicism	26.5%
12	Chimerism	26.5%
13	Infarction	25.4%
14	Postoperative Hemorrhage	25.4%
15	Shock, Hemorrhagic	25.4%
16	Systemic Inflammatory Response Syndrome	25.4%
17	Micronuclei, Chromosome-Defective	23.3%
18	Polydipsia	23.2%
19	Philadelphia Chromosome	22.6%
20	Chromosome Fragility	21.9%
21	Ascites	21.8%
22	Fibrosis	21.8%
23	Gliosis	21.8%
24	Growth Disorders	21.8%
25	Hemorrhage	21.8%
26	Hyperbilirubinemia	21.8%
27	Hyperplasia	21.8%
28	Hypomenorrhea	21.8%
29	Inflammation	21.8%
30	Intraoperative Complications	21.8%
31	Ischemia	21.8%
32	Lithiasis	21.8%
33	Malacoplakia	21.8%
34	Menstruation Disturbances	21.8%
35	Metaplasia	21.8%
36	Nerve Degeneration	21.8%
37	Ochronosis	21.8%
38	Polymenorrhea	21.8%
39	Postoperative Complications	21.8%
40	Sclerosis	21.8%
41	Shock	21.8%
42	Ulcer	21.8%
43	Hyperammonemia	21.8%
44	Hyperamylasemia	21.8%
45	Teratogenesis	21.8%
46	Cardiac Death	21.8%
47	Hypovolemia	21.8%
48	Hyperuricemia	21.8%
49	Leukoaraiosis	21.8%
50	Dysbacteriosis	21.8%
51	Delayed Graft Function	21.8%
52	Cirrhosis	21.8%
53	Neointima	21.8%
54	Dysbiosis	21.8%
55	DNA Degradation, Necrotic	21.2%
56	Sudden infant death syndrome	20.8%
57	Clonal Evolution	20%
58	Vascular Remodeling	19.3%
59	Menorrhagia	18.9%
60	Extravasation of Diagnostic and Therapeutic Materials	17.9%
61	Neoplastic Processes	17.9%
62	Necrosis	17.4%
63	Granulomatosis, Orofacial	17.4%
64	Pigmentation Disorders	17.4%
65	Respiratory Aspiration	17.4%
66	Acantholysis	17.1%
67	Dehydration	17.1%
68	Granuloma	17.1%
69	Leukocytosis	17.1%
70	Pleocytosis	17.1%
71	Incisional hernia	16.9%
72	jaundice	16.9%
73	Endotoxic shock	16.3%
74	Septic Shock	16.3%
75	Toxic Shock Syndrome	16.3%
76	Postoperative Nausea and Vomiting	16.1%
77	Pain, Postoperative	16.1%
78	Acute Disease	16.1%
79	Acute-Phase Reaction	16.1%
80	Amenorrhea	16.1%
81	Chronic disease	16.1%
82	Critical Illness	16.1%
83	Sudden death	16.1%
84	Fat necrosis	16.1%
85	Gangrene	16.1%
86	Graft Occlusion, Vascular	16.1%
87	Granuloma, Plasma Cell	16.1%
88	Hematoma	16.1%
89	Iatrogenic Disease	16.1%
90	Multiple Organ Failure	16.1%
91	Oligomenorrhea	16.1%
92	Premenstrual syndrome	16.1%
93	Recurrence	16.1%
94	Retrograde Degeneration	16.1%
95	Retroperitoneal fibrosis	16.1%
96	Serositis	16.1%
97	Subcutaneous Emphysema	16.1%
98	Surgical Wound Dehiscence	16.1%
99	Syndrome	16.1%
100	Wallerian Degeneration	16.1%
101	Pyogenic granuloma	16.1%
102	Exsanguination	16.1%
103	Disease Progression	16.1%
104	Seroma	16.1%
105	Premenstrual Tension	16.1%
106	Delayed Emergence from Anesthesia	16.1%
107	Infant Death	16.1%
108	Anastomotic Leak	16.1%
109	Intraoperative Awareness	16.1%
110	Dysmenorrhea	15.7%
111	Failed Back Surgery Syndrome	15.7%
112	Muscle Weakness	14.6%
113	Eye Hemorrhage	14.5%
114	Hemoptysis	14.1%
115	Ecchymosis	14%
116	Petechiae	14%
117	Purpura	14%
118	Azotemia	13.9%
119	Jaundice, Obstructive	13.9%
120	Tissue Adhesions	13.3%
121	Hematoma, Epidural, Spinal	13.3%
122	Asphyxia	13.2%
123	Granuloma, Respiratory Tract	13.2%
124	Shock, Traumatic	13.2%
125	Disease susceptibility	12.9%
126	Fetal Death	12.9%
127	Foreign-Body Reaction	12.9%
128	Gastrointestinal Hemorrhage	12.9%
129	Hemarthrosis	12.9%
130	Hemoperitoneum	12.9%
131	Hemothorax	12.9%
132	Neoplasm Invasiveness	12.9%
133	Neoplasm Metastasis	12.9%
134	Neoplasm Recurrence, Local	12.9%
135	Postpericardiotomy Syndrome	12.9%
136	Prosthesis Failure	12.9%
137	Reperfusion Injury	12.9%
138	Injection Site Reaction	12.9%
139	Retrobulbar Hemorrhage	12.9%
140	Aseptic Necrosis of Bone	12.9%
141	Peritoneal Fibrosis	12.9%
142	Carcinogenesis	12.9%
143	Neurogenic Inflammation	12.9%
144	Perinatal death	12.9%
145	Infusion site reaction	12.9%
146	Nephrogenic Fibrosing Dermopathy	12.9%
147	Corneal Endothelial Cell Loss	12.9%
148	Encapsulating Peritoneal Sclerosis	12.9%
149	Vasoplegia	12.9%
150	Suppuration	12.9%
151	Nephrogenic Systemic Fibrosis	12.9%
152	Metastasis	12.9%
153	Sinus Arrhythmia	12.7%
154	Atrial Fibrillation	12.7%
155	Atrial Flutter	12.7%
156	Dental Pulp Necrosis	12.7%
157	Granuloma, Foreign-Body	12.7%
158	Mediastinal Emphysema	12.7%
159	Surgical Wound Infection	12.7%
160	Ventricular Fibrillation	12.7%
161	Ventricular Flutter	12.7%
162	Parasystole	12.7%
163	Paroxysmal atrial fibrillation	12.7%
164	Facies	12.7%
165	Bradycardia	12.7%
166	Embryo Loss	12.7%
167	Sick Sinus Syndrome	12.7%
168	Afferent Loop Syndrome	12.6%
169	Short Bowel Syndrome	12.6%
170	Uterine hemorrhage	12.6%
171	No-Reflow Phenomenon	12.6%
172	Enzyme Induction	12.5%
173	Genomic Instability	12.2%
174	Cardiotoxicity	12.2%
175	Epistaxis	12.1%
176	Hematoma, Subdural, Spinal	11.9%
177	Hematemesis	11.5%
178	Purpura Fulminans	11.4%
179	Signs and Symptoms	11.3%
180	Pathological Conditions, Anatomical	11.3%
181	Hematoma, Subdural	11.1%
182	Hematoma, Epidural, Cranial	11.1%
183	Drowning	10.8%
184	Cross Infection	10.6%
185	Hyphema	10.6%
186	Retinal Neovascularization	10.6%
187	Septicemia	10.6%
188	Vitreous Hemorrhage	10.6%
189	Sepsis	10.6%
190	Fetal Growth Retardation	10.6%
191	Abscess	10.5%
192	Empyema	10.5%
193	Femur Head Necrosis	10.5%
194	Fetal Resorption	10.5%
195	Lymphatic Metastasis	10.5%
196	Neoplasms, Unknown Primary	10.5%
197	Peptic Ulcer Hemorrhage	10.5%
198	Sudden Cardiac Death	10.5%
199	Leukemic Infiltration	10.5%
200	Premenstrual Dysphoric Disorder	10.5%
201	Choroidal Neovascularization	10.5%
202	Primary Graft Dysfunction	10.5%
203	Neoplasm Micrometastasis	10.5%
204	Heart Block	10.5%
205	Tachycardia	10.5%
206	Tachyarrhythmia	10.5%
207	Cicatrix	10.5%
208	Dumping Syndrome	10.4%
209	Cicatrix, Hypertrophic	10.4%
210	Sinus Arrest, Cardiac	10.4%
211	Hematuria	10.4%
212	Granuloma Annulare	10.4%
213	Metrorrhagia	10.4%
214	Brain Death	10.4%
215	Shock, Cardiogenic	10.3%
216	Phantom pain	10.1%
217	Phantom Limb Pain	10.1%
218	Hematoma, Subdural, Intracranial	9.9%
219	Hematoma, Subdural, Chronic	9.9%
220	Hematoma, Subdural, Acute	9.9%
221	Viremia	9.8%
222	Parasitemia	9.8%
223	Giant Cell Epulis	9%
224	Retinal Hemorrhage	8.9%
225	Long QT Syndrome	8.9%
226	Choroid Hemorrhage	8.8%
227	Melena	8.8%
228	Microsatellite Instability	8.8%
229	Thrombocytopenic purpura	8.7%
230	Postpartum Hemorrhage	8.7%
231	Gingival Hemorrhage	8.6%
232	Keloid	8.6%
233	Stillbirth	8.6%
234	Adams-Stokes Syndrome	8.6%
235	Atrioventricular Block	8.6%
236	Bundle-Branch Block	8.6%
237	Atrial Premature Complexes	8.6%
238	Sinoatrial Block	8.6%
239	Tachycardia, Paroxysmal	8.6%
240	Supraventricular tachycardia	8.6%
241	Tachycardia, Ventricular	8.6%
242	Tachycardia, Reciprocating	8.6%
243	Subarachnoid Hemorrhage	8.5%
244	Cerebral Hemorrhage	8.5%
245	Purpura, Hyperglobulinemic	8.5%
246	Bacteremia	7.9%
247	Subacute Combined Degeneration	7.8%
248	Cell Transformation, Viral	7.8%
249	Fungemia	7.8%
250	Eosinophilic Granuloma	7.7%
251	Abdominal Pain	7.7%
252	Tachycardia, Atrioventricular Nodal Reentry	7.6%
253	Tachycardia, Ectopic Atrial	7.6%
254	Tachycardia, Ectopic Junctional	7.6%
255	Sinus Tachycardia	7.6%
256	Torsades de Pointes	7.6%
257	Accelerated Idioventricular Rhythm	7.6%
258	Purpura, Thrombotic Thrombocytopenic	7.6%
259	Cellulitis	7.5%
260	Endotoxemia	7.3%
261	Asthenia	7.3%
262	Body Temperature Changes	7.3%
263	Calculi	7.3%
264	Cyanosis	7.3%
265	Edema	7.3%
266	Failure to Thrive	7.3%
267	Fatigue	7.3%
268	Feminization	7.3%
269	Fetal Distress	7.3%
270	Hernia	7.3%
271	Hypertrophy	7.3%
272	Motion Sickness	7.3%
273	Nails, Malformed	7.3%
274	polyps	7.3%
275	Rupture, Spontaneous	7.3%
276	Signs and Symptoms, Digestive	7.3%
277	Signs and Symptoms, Respiratory	7.3%
278	Skin Manifestations	7.3%
279	Chills	7.3%
280	Lassitude	7.3%
281	Enterocele	7.3%
282	Atheroma	7.3%
283	Pseudophakia	7.3%
284	Urological Manifestations	7.3%
285	Stenosis	7.3%
286	Facial asymmetry	7.3%
287	Mobility Limitation	7.3%
288	Somnolence	7.3%
289	Plaque, Amyloid	7.3%
290	Plaque, Atherosclerotic	7.3%
291	Romano-Ward Syndrome	7.3%
292	Kernicterus	6.9%
293	Granuloma, Laryngeal	6.6%
294	Abdomen, Acute	6.6%
295	Myocardial Reperfusion Injury	6.4%
296	Eye pain	6.4%
297	Renal Colic	6.4%
298	Muscular Atrophy	6.4%
299	Autoimmune thrombocytopenia	6.1%
300	Immune thrombocytopenic purpura	6.1%
301	Cyst	6%
302	Eye Manifestations	6%
303	Neurologic Manifestations	6%
304	Leukoplakia	5.8%
305	Cardiac Output, High	5.8%
306	Myocardial Stunning	5.8%
307	Reticulocytosis	5.8%
308	Low Cardiac Output Syndrome	5.8%
309	Airway Remodeling	5.8%
310	Ventricular Remodeling	5.7%
311	Alopecia	5.7%
312	Intermittent Claudication	5.7%
313	Androgenetic Alopecia	5.7%
314	Waterhouse-Friderichsen Syndrome	5.5%
315	Sarcopenia	5.4%
316	Candidemia	5.4%
317	Anorexia	5.4%
318	Anoxia	5.4%
319	Constipation	5.4%
320	Diarrhea	5.4%
321	Dyspepsia	5.4%
322	Eructation	5.4%
323	Fever	5.4%
324	Flatulence	5.4%
325	Flushing	5.4%
326	Halitosis	5.4%
327	Heartburn	5.4%
328	Diaphragmatic Hernia	5.4%
329	Hiccough	5.4%
330	Hypercalciuria	5.4%
331	Hypercapnia	5.4%
332	Hyperphagia	5.4%
333	Intestinal Polyps	5.4%
334	Nausea	5.4%
335	Pallor	5.4%
336	Psychophysiologic Disorders	5.4%
337	Splenomegaly	5.4%
338	Vomiting	5.4%
339	Hypocapnia	5.4%
340	Dyschezia	5.4%
341	Hypoxia	5.4%
342	Hyperoxia	5.4%
343	Lower Urinary Tract Symptoms	5.4%
344	Hypoxemia	5.4%
345	Urinoma	5.4%
346	Basal Ganglia Hemorrhage	5%
347	Hypergammaglobulinemia	4.8%
348	Putaminal Hemorrhage	4.7%
349	Diverticulum	4.7%
350	Diverticulosis	4.7%
351	Gait Ataxia	4.6%
352	Back Pain	4.4%
353	Bulimia	4.4%
354	Neck Pain	4.4%
355	Chest Pain	4.4%
356	Colonic Polyps	4.4%
357	Dizziness	4.4%
358	Dysuria	4.4%
359	Facial Pain	4.4%
360	Fever of Unknown Origin	4.4%
361	Flank Pain	4.4%
362	Headache	4.4%
363	Nocturia	4.4%
364	Pain, Intractable	4.4%
365	Pelvic Pain	4.4%
366	Snoring	4.4%
367	Chronic pain	4.4%
368	Lightheadedness	4.4%
369	Pain, Referred	4.4%
370	Prostatism	4.4%
371	Throbbing Headache	4.4%
372	Labor Pain	4.4%
373	Cancer Pain	4.4%
374	Nociceptive Pain	4.4%
375	Respiratory Tract Fistula	4.4%
376	Apnea	4.3%
377	Cheyne-Stokes Respiration	4.3%
378	Decerebrate State	4.3%
379	Dyspnea	4.3%
380	Cardiomegaly	4.3%
381	Hemiparesis	4.3%
382	Hepatomegaly	4.3%
383	Hyperventilation	4.3%
384	Meningism	4.3%
385	Mouth Breathing	4.3%
386	Paresis	4.3%
387	Parovarian Cyst	4.3%
388	Pruritus	4.3%
389	Seizures	4.3%
390	Sensation Disorders	4.3%
391	Sneezing	4.3%
392	Spermatocele	4.3%
393	Erythema	4.3%
394	Oral Fistula	4.3%
395	Complex partial seizures	4.3%
396	Necrolytic Migratory Erythema	4.3%
397	Tachypnea	4.3%
398	Monoparesis	4.3%
399	Cutaneous Fistula	4.3%
400	Gait Disorders, Neurologic	4.3%
401	Neuromuscular Manifestations	4.3%
402	Cardiac Hypertrophy	4.3%
403	Edema, Cardiac	4.2%
404	Mental Fatigue	4.2%
405	Hirsutism	4.2%
406	Orthostatic intolerance	4.2%
407	Hypoventilation	4.2%
408	Hoarseness	4.2%
409	Vaginal Fistula	4.2%
410	Rectocele	4.2%
411	Body Weight Changes	4.2%
412	Akathisia	4%
413	Restlessness	4%
414	Psychomotor Agitation	4%
415	Vesicovaginal Fistula	4%
416	Emaciation	4%
417	Low Back Pain	4%
418	Visceral Pain	4%
419	Gait Apraxia	3.9%
420	Sleep Wake Disorders	3.7%
421	Cachexia	3.7%
422	Pupil Disorders	3.7%
423	Neurobehavioral Manifestations	3.7%
424	Nasal Polyps	3.6%
425	Alexia	3.6%
426	Dyslexia	3.6%
427	Biliary Fistula	3.5%
428	Gastric Fistula	3.5%
429	Congenital diaphragmatic hernia	3.5%
430	Morning Sickness	3.5%
431	Pleural Rub	3.5%
432	Rales	3.5%
433	Respiratory Sounds	3.5%
434	Rhonchi	3.5%
435	Stridor	3.5%
436	Wheezing	3.5%
437	Asterixis	3.5%
438	Ballismus	3.5%
439	Vertigo	3.5%
440	Anosmia	3.5%
441	Ataxia	3.5%
442	Athetosis	3.5%
443	Catalepsy	3.5%
444	Dental Fistula	3.5%
445	Dystonia	3.5%
446	Hemiplegia	3.5%
447	Locked-In Syndrome	3.5%
448	Muscle Hypertonia	3.5%
449	Muscle hypotonia	3.5%
450	Myoclonus	3.5%
451	Myotonia	3.5%
452	Neuralgia	3.5%
453	Oroantral Fistula	3.5%
454	Paraplegia	3.5%
455	Pseudobulbar Palsy	3.5%
456	Quadriplegia	3.5%
457	Spasm	3.5%
458	Spastic Paraplegia	3.5%
459	Status Epilepticus	3.5%
460	Taste Disorders	3.5%
461	Tremor	3.5%
462	Monoplegia	3.5%
463	Hypokinesia	3.5%
464	Left Ventricular Hypertrophy	3.5%
465	Gastroparesis	3.5%
466	Right Ventricular Hypertrophy	3.5%
467	Paraparesis	3.5%
468	Bradykinesia	3.5%
469	Waxy flexibility	3.5%
470	Action Tremor	3.5%
471	Resting Tremor	3.5%
472	Dysosmia	3.5%
473	Quadriparesis	3.5%
474	Olfaction Disorders	3.5%
475	Myokymia	3.5%
476	Somatosensory Disorders	3.5%
477	Neuropathic pain	3.5%
478	Hyperkinesia	3.5%
479	Intention tremor	3.5%
480	Pain	3.5%
481	Livedo Reticularis	3.5%
482	Ache	3.5%
483	Rectal Prolapse	3.5%
484	Uterine Prolapse	3.5%
485	Vaginal Prolapse	3.5%
486	Meningocele	3.5%
487	Oliguria	3.5%
488	Polyuria	3.5%
489	Proteinuria	3.5%
490	Urinary Calculi	3.5%
491	Encephalocele	3.5%
492	Weight Gain	3.5%
493	Underweight	3.4%
494	Overweight	3.4%
495	Body Weight	3.4%
496	Alice in Wonderland Syndrome	3.3%
497	Umbilical hernia	3.2%
498	Toothache	3.2%
499	Hyperemesis Gravidarum	3.1%
500	Dysgeusia	3.1%
501	Formication	3.1%
502	Hyperalgesia	3.1%
503	Hyperesthesia	3.1%
504	Hypesthesia	3.1%
505	Language Disorders	3.1%
506	Numbness	3.1%
507	Paresthesia	3.1%
508	Paraparesis, Spastic	3.1%
509	Trismus	3.1%
510	Epilepsia Partialis Continua	3.1%
511	Hypogeusia	3.1%
512	Brown-Sequard Syndrome	3.1%
513	Lockjaw	3.1%
514	Allodynia	3.1%
515	Ageusia	3.1%
516	Voice Disorders	3.1%
517	Voice Disturbance	3.1%
518	Gagging	3%
519	Vision Disorders	3%
520	Metamorphopsia	3%
521	Visual Impairment	3%
522	Bronchial Fistula	3%
523	Metatarsalgia	3%
524	Pancreatic Fistula	3%
525	Leukoplakia, Oral	3%
526	Agraphia	2.9%
527	Anomia	2.9%
528	Cluttering	2.9%
529	Language Development Disorders	2.9%
530	Speech Disorders	2.9%
531	Syncope	2.9%
532	Stupor	2.9%
533	Dysgraphia	2.9%
534	Presyncope	2.9%
535	Dyslalia	2.9%
536	Anisocoria	2.9%
537	Confusion	2.9%
538	Facial paralysis	2.9%
539	Intestinal Fistula	2.9%
540	Lethargy	2.9%
541	Memory Disorders	2.9%
542	Muscle Cramp	2.9%
543	Perceptual Disorders	2.9%
544	Psychomotor Disorders	2.9%
545	Tonic Pupil	2.9%
546	Anhedonia	2.9%
547	Disorientation	2.9%
548	Gastroschisis	2.9%
549	Enterocutaneous Fistula	2.9%
550	Fetal Hypoxia	2.9%
551	Facial Paresis	2.9%
552	Memory Loss	2.9%
553	Hemisensory Neglect	2.9%
554	Dysacusis	2.9%
555	Dyspnea, Paroxysmal	2.9%
556	Mastodynia	2.9%
557	Respiratory Paralysis	2.9%
558	Salivary Gland Fistula	2.9%
559	Chorea	2.9%
560	Cystocele	2.9%
561	Tetany	2.9%
562	Urinary Incontinence	2.9%
563	Breakthrough Pain	2.9%
564	Albuminuria	2.8%
565	Hemoglobinuria	2.8%
566	Aphasia	2.8%
567	Articulation Disorders	2.8%
568	Echolalia	2.8%
569	Stuttering	2.8%
570	Dysphasia	2.8%
571	Dysarthria	2.8%
572	Diplopia	2.6%
573	Muscle Rigidity	2.6%
574	Muscle Spasticity	2.6%
575	Scotoma	2.6%
576	Photophobia	2.6%
577	Cogwheel Rigidity	2.6%
578	Hemifacial Spasm	2.6%
579	Amaurosis	2.6%
580	Blindness	2.6%
581	Nuchal Rigidity	2.6%
582	Angina Pectoris	2.6%
583	Jet Lag Syndrome	2.6%
584	Agnosia	2.6%
585	Apraxias	2.6%
586	Hallucinations	2.6%
587	Hemianopsia	2.6%
588	Hyperacusis	2.6%
589	Tinnitus	2.6%
590	Visual Agnosia	2.6%
591	Anosognosia	2.6%
592	Wernicke-Korsakoff Syndrome	2.6%
593	Phonophobia	2.6%
594	Hearing Loss	2.6%
595	Reflex, Abnormal	2.6%
596	Hyporeflexia	2.6%
597	Hyperreflexia	2.6%
598	Cerebellar Ataxia	2.6%
599	Torticollis	2.6%
600	Sciatica	2.6%
601	Urge Incontinence	2.6%
602	Tardive Dyskinesia	2.6%
603	Birth Weight	2.5%
604	Consciousness Disorders	2.5%
605	Mental Retardation	2.5%
606	Depressed Level of Consciousness	2.5%
607	Mental deficiency	2.5%
608	Intellectual Disability	2.5%
609	Catatonia	2.5%
610	Musculoskeletal Pain	2.5%
611	Ophthalmoplegia	2.5%
612	External Ophthalmoplegia	2.5%
613	Aphonia	2.5%
614	Arthralgia	2.5%
615	Sleep Deprivation	2.5%
616	Polyarthralgia	2.5%
617	Dysphonia	2.5%
618	Cerebrospinal Fluid Otorrhea	2.4%
619	Cerebrospinal Fluid Rhinorrhea	2.4%
620	Amaurosis Fugax	2.4%
621	Blindness, Cortical	2.4%
622	Dyscalculia	2.4%
623	Obesity	2.4%
624	Angina, Unstable	2.4%
625	Deafness	2.4%
626	Hearing Loss, Sudden	2.4%
627	Gerstmann Syndrome	2.4%
628	Hearing Loss, Bilateral	2.4%
629	Hearing Loss, High-Frequency	2.4%
630	Hearing Loss, Mixed Conductive-Sensorineural	2.4%
631	Prosopagnosia	2.4%
632	Apraxia, Ideomotor	2.4%
633	Persistent Vegetative State	2.4%
634	Charles Bonnet Syndrome	2.4%
635	Hearing Loss, Unilateral	2.4%
636	Complete Hearing Loss	2.4%
637	Alien Hand Syndrome	2.4%
638	Deaf Mutism	2.4%
639	Mutism	2.4%
640	Selective Mutism	2.4%
641	Angina Pectoris, Variant	2.3%
642	Alexia, Pure	2.3%
643	Amblyopia	2.2%
644	Amnesia	2.2%
645	Delirium	2.2%
646	Horner Syndrome	2.2%
647	Dissociative Amnesia	2.2%
648	Color blindness	2.2%
649	Global Amnesia	2.2%
650	Rectal Fistula	2.2%
651	Anal Fistula	2.2%
652	Vocal Cord Paralysis	2.2%
653	Shoulder Pain	2.2%
654	Pediatric Obesity	2.2%
655	Urinary Bladder Fistula	2.1%
656	Tinea Pedis	2.1%
657	Retrograde amnesia	2.1%
658	Amnesia, Anterograde	2.1%
659	Hydrops Fetalis	2%
660	Fetal Weight	2%
661	Akathisia, Drug-Induced	2%
662	Myalgia	1.9%
663	Dyskinesia, Drug-Induced	1.9%
664	Alcohol Withdrawal Seizures	1.9%
665	Arteriovenous fistula	1.9%
666	Amnesia, Transient Global	1.8%
667	Auditory Perceptual Disorders	1.7%
668	Kidney Calculi	1.7%
669	Ureteral Calculi	1.7%
670	Ophthalmoplegic Migraine	1.5%
671	Progressive supranuclear palsy	1.5%
672	Kearns-Sayre syndrome	1.1%

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