MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Premenstrual Dysphoric Disorder

(UMLS:C0520676)

Definition:: A condition in which a woman suffers from severe depression, irritability, and tension before MENSTRUATION. Premenstrual dysphoric disorder (PMDD) may involve a wide range of physical or emotional symptoms, which are more severe and debilitating than those seen with premenstrual syndrome (PMS), and which include at least one mood-related symptom. Symptoms usually stop when, or shortly after, menstruation begins.
UMLS ID:: C0520676
MeSH ID:: D065446

Classification 1:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.568.968.500

Classification 2:

Name:

Mental Disorders
MeSH Tree Number(s):: F03.600.300.550

Synonym(s)

Premenstrual Dysphoric Disorder

Premenstrual dysphoric disorder

disorder dysphoric premenstrual

pmdd

premenstrual disorder

premenstrual dysphoric disorder

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Norgestrel	FAERS: 10	US FAERS
2	NuvaRing	FAERS: 3	US FAERS
3	Sertraline	FAERS: 3	US FAERS
4	etonogestrel	FAERS: 3	US FAERS
5	Paroxetine	FAERS: 2	US FAERS
6	Citalopram	FAERS: 1	US FAERS
7	Copper	FAERS: 1	US FAERS
8	Fexofenadine hydrochloride and pseudoephedrine hydrochloride	FAERS: 1	US FAERS
9	Lurasidone Hydrochloride	FAERS: 1	US FAERS
10	Medroxyprogesterone Acetate	FAERS: 1	US FAERS
11	Sertraline	FAERS: 1	US FAERS
12	Xulane	FAERS: 1	US FAERS
13	norgestimate, ethinyl estradiol drug combination	FAERS: 1	US FAERS
14	zaleplon	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Dysthymic Disorder	30.8%
2	Seasonal Affective Disorder	30.8%
3	Depression, Postpartum	23.1%
4	Amenorrhea	23.1%
5	Oligomenorrhea	23.1%
6	Cyclothymic Disorder	20.2%
7	Dysmenorrhea	18.4%
8	Menorrhagia	17.6%
9	Polydipsia	17.1%
10	Ascites	16.9%
11	Fibrosis	16.9%
12	Gliosis	16.9%
13	Growth Disorders	16.9%
14	Hemorrhage	16.9%
15	Hyperbilirubinemia	16.9%
16	Hyperplasia	16.9%
17	Inflammation	16.9%
18	Intraoperative Complications	16.9%
19	Ischemia	16.9%
20	Lithiasis	16.9%
21	Malacoplakia	16.9%
22	Metaplasia	16.9%
23	Nerve Degeneration	16.9%
24	Ochronosis	16.9%
25	Postoperative Complications	16.9%
26	Sclerosis	16.9%
27	Shock	16.9%
28	Ulcer	16.9%
29	Hyperammonemia	16.9%
30	Hyperamylasemia	16.9%
31	Teratogenesis	16.9%
32	Cardiac Death	16.9%
33	Hypovolemia	16.9%
34	Hyperuricemia	16.9%
35	Leukoaraiosis	16.9%
36	Dysbacteriosis	16.9%
37	Delayed Graft Function	16.9%
38	Cirrhosis	16.9%
39	Neointima	16.9%
40	Dysbiosis	16.9%
41	Infarction	14.9%
42	Postoperative Hemorrhage	14.9%
43	Shock, Hemorrhagic	14.9%
44	Systemic Inflammatory Response Syndrome	14.9%
45	Neurotic Disorders	14.2%
46	Vascular Remodeling	13.8%
47	Extravasation of Diagnostic and Therapeutic Materials	13.3%
48	Neoplastic Processes	13.3%
49	Necrosis	12.8%
50	Granulomatosis, Orofacial	12.8%
51	Pigmentation Disorders	12.8%
52	Respiratory Aspiration	12.8%
53	Acantholysis	12.6%
54	Chromosome Aberrations	12.6%
55	Dehydration	12.6%
56	Granuloma	12.6%
57	Leukocytosis	12.6%
58	Pleocytosis	12.6%
59	Anxiety Disorders	11.8%
60	Avoidant Personality Disorder	11.8%
61	Dissociative disorder	11.8%
62	Frigidity	11.8%
63	Hypoactive Sexual Desire Disorder	11.8%
64	Disruptive, Impulse Control, and Conduct Disorders	11.8%
65	Intermittent Explosive Disorder	11.8%
66	Kleptomania	11.8%
67	Narcissistic Personality Disorder	11.8%
68	Personality Disorders	11.8%
69	Sexual Aversion Disorder	11.8%
70	Somatoform Disorder	11.8%
71	Dissociation	11.8%
72	Motor Disorders	11.8%
73	Schizophrenia Spectrum and Other Psychotic Disorders	11.8%
74	Neurodevelopmental Disorders	11.8%
75	Neurocognitive Disorders	11.8%
76	Feeding and Eating Disorders	11.8%
77	Signs and Symptoms	10.6%
78	Pathological Conditions, Anatomical	10.6%
79	Genomic Instability	10.5%
80	Separation Anxiety Disorder	10.3%
81	Chromosomal Instability	10%
82	Incisional hernia	9.9%
83	jaundice	9.9%
84	Azotemia	9.9%
85	Acute Disease	9.9%
86	Acute-Phase Reaction	9.9%
87	Chronic disease	9.9%
88	Critical Illness	9.9%
89	Sudden death	9.9%
90	Fat necrosis	9.9%
91	Gangrene	9.9%
92	Graft Occlusion, Vascular	9.9%
93	Granuloma, Plasma Cell	9.9%
94	Hematoma	9.9%
95	Iatrogenic Disease	9.9%
96	Multiple Organ Failure	9.9%
97	Recurrence	9.9%
98	Retrograde Degeneration	9.9%
99	Retroperitoneal fibrosis	9.9%
100	Serositis	9.9%
101	Subcutaneous Emphysema	9.9%
102	Surgical Wound Dehiscence	9.9%
103	Syndrome	9.9%
104	Wallerian Degeneration	9.9%
105	Pyogenic granuloma	9.9%
106	Exsanguination	9.9%
107	Disease Progression	9.9%
108	Seroma	9.9%
109	Delayed Emergence from Anesthesia	9.9%
110	Infant Death	9.9%
111	Anastomotic Leak	9.9%
112	Intraoperative Awareness	9.9%
113	Sudden infant death syndrome	9.8%
114	Muscle Weakness	9.6%
115	Sleep Wake Disorders	9.4%
116	Drug abuse	9.2%
117	Substance Dependence	9.2%
118	Substance-Related Disorders	9.2%
119	Drug Dependence	9.2%
120	Pain, Postoperative	9%
121	Failed Back Surgery Syndrome	8.6%
122	Cardiotoxicity	8.5%
123	Postoperative Nausea and Vomiting	8.5%
124	Eye Hemorrhage	8.3%
125	Hemoptysis	8.1%
126	Ecchymosis	7.9%
127	Petechiae	7.9%
128	Purpura	7.9%
129	Asphyxia	7.8%
130	Granuloma, Respiratory Tract	7.8%
131	Shock, Traumatic	7.8%
132	Disease susceptibility	7.6%
133	Fetal Death	7.6%
134	Foreign-Body Reaction	7.6%
135	Gastrointestinal Hemorrhage	7.6%
136	Hemarthrosis	7.6%
137	Hemoperitoneum	7.6%
138	Hemothorax	7.6%
139	Neoplasm Invasiveness	7.6%
140	Neoplasm Metastasis	7.6%
141	Neoplasm Recurrence, Local	7.6%
142	Postpericardiotomy Syndrome	7.6%
143	Prosthesis Failure	7.6%
144	Reperfusion Injury	7.6%
145	Injection Site Reaction	7.6%
146	Retrobulbar Hemorrhage	7.6%
147	Aseptic Necrosis of Bone	7.6%
148	Peritoneal Fibrosis	7.6%
149	Carcinogenesis	7.6%
150	Neurogenic Inflammation	7.6%
151	Perinatal death	7.6%
152	Infusion site reaction	7.6%
153	Nephrogenic Fibrosing Dermopathy	7.6%
154	Corneal Endothelial Cell Loss	7.6%
155	Encapsulating Peritoneal Sclerosis	7.6%
156	Vasoplegia	7.6%
157	Suppuration	7.6%
158	Nephrogenic Systemic Fibrosis	7.6%
159	Metastasis	7.6%
160	Sinus Arrhythmia	7.4%
161	Atrial Fibrillation	7.4%
162	Atrial Flutter	7.4%
163	Dental Pulp Necrosis	7.4%
164	Granuloma, Foreign-Body	7.4%
165	Mediastinal Emphysema	7.4%
166	Surgical Wound Infection	7.4%
167	Ventricular Fibrillation	7.4%
168	Ventricular Flutter	7.4%
169	Parasystole	7.4%
170	Paroxysmal atrial fibrillation	7.4%
171	Facies	7.4%
172	Bradycardia	7.4%
173	Embryo Loss	7.4%
174	Afferent Loop Syndrome	7.4%
175	Sex Chromosome Aberrations	7.4%
176	Short Bowel Syndrome	7.4%
177	Uterine hemorrhage	7.4%
178	No-Reflow Phenomenon	7.4%
179	Endotoxic shock	6.8%
180	Septic Shock	6.8%
181	Toxic Shock Syndrome	6.8%
182	Epistaxis	6.8%
183	Adjustment Disorders	6.7%
184	Affective Disorders, Psychotic	6.7%
185	Agoraphobia	6.7%
186	Anorexia Nervosa	6.7%
187	Antisocial Personality Disorder	6.7%
188	Bipolar Disorder	6.7%
189	Body Dysmorphic Disorders	6.7%
190	Borderline Personality Disorder	6.7%
191	Capgras Syndrome	6.7%
192	Child Behavior Disorders	6.7%
193	Developmental Disabilities	6.7%
194	Child Development Disorders, Pervasive	6.7%
195	Claustrophobia	6.7%
196	Cognition Disorders	6.7%
197	Conversion disorder	6.7%
198	Dependent Personality Disorder	6.7%
199	Developmental Coordination Disorder	6.7%
200	Exhibitionism	6.7%
201	Factitious Disorders	6.7%
202	Firesetting Behavior	6.7%
203	Head Banging	6.7%
204	Histrionic Personality Disorder	6.7%
205	Hypochondriasis	6.7%
206	Masochism	6.7%
207	Motor Skills Disorders	6.7%
208	Dissociative Identity Disorder	6.7%
209	Neurasthenia	6.7%
210	Obsessive-Compulsive Disorder	6.7%
211	Oppositional Defiant Disorder	6.7%
212	Panic Disorder	6.7%
213	Paranoid Personality Disorder	6.7%
214	Pedophilia	6.7%
215	Pseudodementia	6.7%
216	Psychotic Disorders	6.7%
217	Sadism	6.7%
218	Schizoaffective Disorder	6.7%
219	Schizoid Personality Disorder	6.7%
220	Schizophrenia	6.7%
221	Schizophrenia, Childhood	6.7%
222	Schizotypal Personality Disorder	6.7%
223	Stereotypic Movement Disorder	6.7%
224	Transvestism	6.7%
225	Trichotillomania	6.7%
226	Voyeurism	6.7%
227	Attention Deficit and Disruptive Behavior Disorders	6.7%
228	Hyperkinetic Heart Syndrome	6.7%
229	Reactive Attachment Disorder	6.7%
230	Sexual and Gender Disorders	6.7%
231	Gender Dysphoria	6.7%
232	Paranoia	6.7%
233	Compulsive Personality Disorder	6.7%
234	Bulimia Nervosa	6.7%
235	Tissue Adhesions	6.5%
236	Hematoma, Epidural, Spinal	6.5%
237	Chromosome Fragility	6.5%
238	Jaundice, Obstructive	6.5%
239	Drowning	6.2%
240	Fetal Growth Retardation	6%
241	DNA Degradation, Necrotic	6%
242	Aneuploidy	6%
243	Polyploidy	6%
244	Microsatellite Instability	6%
245	Heart Block	6%
246	Tachycardia	6%
247	Tachyarrhythmia	6%
248	Cicatrix	6%
249	Hematuria	5.9%
250	Granuloma Annulare	5.9%
251	Chromosome Breakage	5.9%
252	Brain Death	5.9%
253	Shock, Cardiogenic	5.9%
254	Psychoses, Substance-Induced	5.7%
255	Asthenia	5.6%
256	Body Temperature Changes	5.6%
257	Calculi	5.6%
258	Cyanosis	5.6%
259	Edema	5.6%
260	Failure to Thrive	5.6%
261	Fatigue	5.6%
262	Feminization	5.6%
263	Fetal Distress	5.6%
264	Hernia	5.6%
265	Hypertrophy	5.6%
266	Motion Sickness	5.6%
267	Nails, Malformed	5.6%
268	polyps	5.6%
269	Rupture, Spontaneous	5.6%
270	Signs and Symptoms, Digestive	5.6%
271	Signs and Symptoms, Respiratory	5.6%
272	Skin Manifestations	5.6%
273	Chills	5.6%
274	Lassitude	5.6%
275	Enterocele	5.6%
276	Atheroma	5.6%
277	Pseudophakia	5.6%
278	Urological Manifestations	5.6%
279	Stenosis	5.6%
280	Facial asymmetry	5.6%
281	Mobility Limitation	5.6%
282	Somnolence	5.6%
283	Plaque, Amyloid	5.6%
284	Plaque, Atherosclerotic	5.6%
285	Sick Sinus Syndrome	5.6%
286	Trisomy	5.6%
287	Hematemesis	5.2%
288	Purpura Fulminans	5.2%
289	Marijuana Abuse	5.1%
290	Opioid-Related Disorders	5.1%
291	Nicotine Dependence	5.1%
292	Opioid abuse	5.1%
293	Parasomnia	5.1%
294	Phencyclidine Abuse	5.1%
295	Substance Abuse, Intravenous	5.1%
296	Substance Withdrawal Syndrome	5.1%
297	Tobacco Use Disorder	5.1%
298	Alcohol-Related Disorders	5.1%
299	Amphetamine-Related Disorders	5.1%
300	Cocaine-Related Disorders	5.1%
301	Dyssomnias	5.1%
302	Giant Cell Epulis	5.1%
303	Gambling	5%
304	Premature Ejaculation	5%
305	Erectile dysfunction	5%
306	Dementia	5%
307	Cross Infection	5%
308	Hyphema	5%
309	Retinal Neovascularization	5%
310	Septicemia	5%
311	Vitreous Hemorrhage	5%
312	Sepsis	5%
313	Long QT Syndrome	4.9%
314	Abscess	4.9%
315	Empyema	4.9%
316	Femur Head Necrosis	4.9%
317	Fetal Resorption	4.9%
318	Lymphatic Metastasis	4.9%
319	Neoplasms, Unknown Primary	4.9%
320	Peptic Ulcer Hemorrhage	4.9%
321	Sudden Cardiac Death	4.9%
322	Leukemic Infiltration	4.9%
323	Choroidal Neovascularization	4.9%
324	Primary Graft Dysfunction	4.9%
325	Neoplasm Micrometastasis	4.9%
326	Dumping Syndrome	4.9%
327	Cicatrix, Hypertrophic	4.9%
328	Sinus Arrest, Cardiac	4.9%
329	Micronuclei, Chromosome-Defective	4.9%
330	Hematoma, Subdural, Spinal	4.9%
331	Metrorrhagia	4.9%
332	Hematoma, Subdural	4.8%
333	Hematoma, Epidural, Cranial	4.8%
334	Mutism	4.7%
335	Selective Mutism	4.7%
336	Consciousness Disorders	4.5%
337	Mental Retardation	4.5%
338	Depressed Level of Consciousness	4.5%
339	Mental deficiency	4.5%
340	Intellectual Disability	4.5%
341	Cyst	4.4%
342	Eye Manifestations	4.4%
343	Neurologic Manifestations	4.4%
344	Combat Disorders	4.4%
345	Hysteria	4.4%
346	Schizophrenia, Catatonic	4.4%
347	Schizophrenia, Disorganized	4.4%
348	Post-Traumatic Stress Disorder	4.4%
349	Attention Deficit Disorder	4.4%
350	Conduct Disorder	4.4%
351	Social Communication Disorder	4.4%
352	Psychological Trauma	4.4%
353	Hoarding Disorder	4.4%
354	Phonological Disorder	4.4%
355	Subacute Combined Degeneration	4.3%
356	Leukoplakia	4.3%
357	Cardiac Output, High	4.3%
358	Myocardial Stunning	4.3%
359	Reticulocytosis	4.3%
360	Low Cardiac Output Syndrome	4.3%
361	Airway Remodeling	4.3%
362	Eosinophilic Granuloma	4.2%
363	Ventricular Remodeling	4.2%
364	Alopecia	4.2%
365	Intermittent Claudication	4.2%
366	Androgenetic Alopecia	4.2%
367	Phantom pain	4.2%
368	Phantom Limb Pain	4.2%
369	Neonatal Abstinence Syndrome	4.1%
370	Amnesia	4.1%
371	Delirium	4.1%
372	Dissociative Amnesia	4.1%
373	Global Amnesia	4.1%
374	Abdominal Pain	4.1%
375	Retinal Hemorrhage	4.1%
376	Choroid Hemorrhage	4%
377	Melena	4%
378	Dyspareunia	4%
379	Postpartum Hemorrhage	3.9%
380	Gingival Hemorrhage	3.9%
381	Keloid	3.9%
382	Monosomy	3.9%
383	Tetraploidy	3.9%
384	Stillbirth	3.9%
385	Adams-Stokes Syndrome	3.9%
386	Atrioventricular Block	3.9%
387	Bundle-Branch Block	3.9%
388	Atrial Premature Complexes	3.9%
389	Sinoatrial Block	3.9%
390	Tachycardia, Paroxysmal	3.9%
391	Supraventricular tachycardia	3.9%
392	Tachycardia, Ventricular	3.9%
393	Tachycardia, Reciprocating	3.9%
394	Subarachnoid Hemorrhage	3.9%
395	Cerebral Hemorrhage	3.9%
396	Viremia	3.9%
397	Parasitemia	3.9%
398	Renal Colic	3.8%
399	Psychoses, Alcoholic	3.8%
400	Thrombocytopenic purpura	3.8%
401	Kernicterus	3.7%
402	Purpura, Hyperglobulinemic	3.7%
403	Hematoma, Subdural, Intracranial	3.6%
404	Hematoma, Subdural, Chronic	3.6%
405	Hematoma, Subdural, Acute	3.6%
406	Dyscalculia	3.4%
407	Hypergammaglobulinemia	3.4%
408	Restless Legs Syndrome	3.4%
409	Cellulitis	3.3%
410	Enuresis	3.3%
411	Eye pain	3.3%
412	Diverticulum	3.3%
413	Diverticulosis	3.3%
414	Alcohol Use Disorder	3.3%
415	Alcoholic Intoxication	3.3%
416	Heroin Dependence	3.3%
417	Morphine Dependence	3.3%
418	Alcohol abuse	3.3%
419	Sleep Talking	3.3%
420	Sleep Disorders, Intrinsic	3.3%
421	Anorexia	3.3%
422	Anoxia	3.3%
423	Constipation	3.3%
424	Diarrhea	3.3%
425	Dyspepsia	3.3%
426	Eructation	3.3%
427	Fever	3.3%
428	Flatulence	3.3%
429	Flushing	3.3%
430	Halitosis	3.3%
431	Heartburn	3.3%
432	Diaphragmatic Hernia	3.3%
433	Hiccough	3.3%
434	Hypercalciuria	3.3%
435	Hypercapnia	3.3%
436	Hyperphagia	3.3%
437	Intestinal Polyps	3.3%
438	Nausea	3.3%
439	Pallor	3.3%
440	Psychophysiologic Disorders	3.3%
441	Sleep Deprivation	3.3%
442	Splenomegaly	3.3%
443	Vomiting	3.3%
444	Hypocapnia	3.3%
445	Dyschezia	3.3%
446	Hypoxia	3.3%
447	Hyperoxia	3.3%
448	Lower Urinary Tract Symptoms	3.3%
449	Hypoxemia	3.3%
450	Urinoma	3.3%
451	Muscular Atrophy	3.3%
452	Alcohol Withdrawal Delirium	3.3%
453	Kluver-Bucy Syndrome	3.3%
454	Alexia, Pure	3.3%
455	Autistic Disorder	3.3%
456	Asperger Syndrome	3.3%
457	Romano-Ward Syndrome	3.2%
458	Bacteremia	3%
459	Alexia	3%
460	Dyslexia	3%
461	Cell Transformation, Viral	3%
462	Fungemia	3%
463	Huntington Disease	2.9%
464	Granuloma, Laryngeal	2.9%
465	Tachycardia, Atrioventricular Nodal Reentry	2.9%
466	Tachycardia, Ectopic Atrial	2.9%
467	Tachycardia, Ectopic Junctional	2.9%
468	Sinus Tachycardia	2.9%
469	Torsades de Pointes	2.9%
470	Accelerated Idioventricular Rhythm	2.9%
471	Jet Lag Syndrome	2.8%
472	Abdomen, Acute	2.8%
473	Retrograde amnesia	2.8%
474	Amnesia, Anterograde	2.8%
475	Myocardial Reperfusion Injury	2.8%
476	Purpura, Thrombotic Thrombocytopenic	2.8%
477	Sleep Bruxism	2.6%
478	Presenile dementia	2.6%
479	Senile dementia	2.6%
480	Binge Drinking	2.6%
481	Creutzfeldt-Jakob disease	2.6%
482	Respiratory Tract Fistula	2.6%
483	Apnea	2.5%
484	Cheyne-Stokes Respiration	2.5%
485	Decerebrate State	2.5%
486	Dyspnea	2.5%
487	Cardiomegaly	2.5%
488	Hemiparesis	2.5%
489	Hepatomegaly	2.5%
490	Hyperventilation	2.5%
491	Meningism	2.5%
492	Mouth Breathing	2.5%
493	Paresis	2.5%
494	Parovarian Cyst	2.5%
495	Pruritus	2.5%
496	Seizures	2.5%
497	Sensation Disorders	2.5%
498	Sneezing	2.5%
499	Spermatocele	2.5%
500	Erythema	2.5%
501	Oral Fistula	2.5%
502	Complex partial seizures	2.5%
503	Necrolytic Migratory Erythema	2.5%
504	Tachypnea	2.5%
505	Monoparesis	2.5%
506	Cutaneous Fistula	2.5%
507	Gait Disorders, Neurologic	2.5%
508	Neuromuscular Manifestations	2.5%
509	Cardiac Hypertrophy	2.5%
510	Edema, Cardiac	2.5%
511	Mental Fatigue	2.5%
512	Hirsutism	2.5%
513	Orthostatic intolerance	2.5%
514	Hypoventilation	2.5%
515	Vaginal Fistula	2.5%
516	Rectocele	2.5%
517	Body Weight Changes	2.4%
518	Disorders of Excessive Somnolence	2.4%
519	Sleep Initiation and Maintenance Disorders	2.4%
520	Night Terrors	2.4%
521	Somnambulism	2.4%
522	Amnesia, Transient Global	2.4%
523	Endotoxemia	2.4%
524	Transient Insomnia	2.4%
525	Sleep Paralysis	2.4%
526	Chronic Insomnia	2.4%
527	REM Sleep Behavior Disorder	2.4%
528	Hypersomnia	2.4%
529	Philadelphia Chromosome	2.4%
530	Waterhouse-Friderichsen Syndrome	2.3%
531	Body Weight	2.3%
532	Sleep Disorders, Circadian Rhythm	2.3%
533	Sarcopenia	2.3%
534	Auditory Perceptual Disorders	2.2%
535	Autoimmune thrombocytopenia	2.2%
536	Immune thrombocytopenic purpura	2.2%
537	Back Pain	2.2%
538	Bulimia	2.2%
539	Neck Pain	2.2%
540	Chest Pain	2.2%
541	Colonic Polyps	2.2%
542	Dizziness	2.2%
543	Dysuria	2.2%
544	Facial Pain	2.2%
545	Fever of Unknown Origin	2.2%
546	Flank Pain	2.2%
547	Headache	2.2%
548	Nocturia	2.2%
549	Pain, Intractable	2.2%
550	Pelvic Pain	2.2%
551	Snoring	2.2%
552	Chronic pain	2.2%
553	Lightheadedness	2.2%
554	Pain, Referred	2.2%
555	Prostatism	2.2%
556	Throbbing Headache	2.2%
557	Labor Pain	2.2%
558	Cancer Pain	2.2%
559	Nociceptive Pain	2.2%
560	Diurnal Enuresis	2.2%
561	Pupil Disorders	2.1%
562	Neurobehavioral Manifestations	2.1%
563	Hoarseness	2.1%
564	Nasal Polyps	2%
565	Narcolepsy	2%
566	Kleine-Levin Syndrome	2%
567	Pleural Rub	2%
568	Rales	2%
569	Respiratory Sounds	2%
570	Rhonchi	2%
571	Stridor	2%
572	Wheezing	2%
573	Asterixis	2%
574	Ballismus	2%
575	Pick Disease of the Brain	2%
576	Vertigo	2%
577	Pain	2%
578	Livedo Reticularis	2%
579	Ache	2%
580	Meningocele	2%
581	Oliguria	2%
582	Polyuria	2%
583	Proteinuria	2%
584	Urinary Calculi	2%
585	Encephalocele	2%
586	Underweight	1.9%
587	Overweight	1.9%
588	Gait Ataxia	1.9%
589	Lewy Body Disease	1.9%
590	Wernicke Encephalopathy	1.9%
591	AIDS Dementia Complex	1.9%
592	Cataplexy	1.8%
593	Basal Ganglia Hemorrhage	1.8%
594	Candidemia	1.7%
595	Voice Disorders	1.7%
596	Voice Disturbance	1.7%
597	Gagging	1.7%
598	Biliary Fistula	1.7%
599	Gastric Fistula	1.7%
600	Congenital diaphragmatic hernia	1.7%
601	Morning Sickness	1.7%
602	Leukoplakia, Oral	1.6%
603	Anosmia	1.6%
604	Ataxia	1.6%
605	Athetosis	1.6%
606	Catalepsy	1.6%
607	Dental Fistula	1.6%
608	Dystonia	1.6%
609	Hemiplegia	1.6%
610	Locked-In Syndrome	1.6%
611	Muscle Hypertonia	1.6%
612	Muscle hypotonia	1.6%
613	Myoclonus	1.6%
614	Myotonia	1.6%
615	Neuralgia	1.6%
616	Oroantral Fistula	1.6%
617	Paraplegia	1.6%
618	Pseudobulbar Palsy	1.6%
619	Quadriplegia	1.6%
620	Spasm	1.6%
621	Spastic Paraplegia	1.6%
622	Status Epilepticus	1.6%
623	Taste Disorders	1.6%
624	Tremor	1.6%
625	Monoplegia	1.6%
626	Hypokinesia	1.6%
627	Left Ventricular Hypertrophy	1.6%
628	Gastroparesis	1.6%
629	Right Ventricular Hypertrophy	1.6%
630	Paraparesis	1.6%
631	Bradykinesia	1.6%
632	Waxy flexibility	1.6%
633	Action Tremor	1.6%
634	Resting Tremor	1.6%
635	Dysosmia	1.6%
636	Quadriparesis	1.6%
637	Olfaction Disorders	1.6%
638	Myokymia	1.6%
639	Somatosensory Disorders	1.6%
640	Neuropathic pain	1.6%
641	Hyperkinesia	1.6%
642	Intention tremor	1.6%
643	Akathisia	1.6%
644	Restlessness	1.6%
645	Psychomotor Agitation	1.6%
646	Rectal Prolapse	1.6%
647	Uterine Prolapse	1.6%
648	Vaginal Prolapse	1.6%
649	Emaciation	1.6%
650	Low Back Pain	1.6%
651	Visceral Pain	1.6%
652	Weight Gain	1.6%
653	Frontotemporal dementia	1.6%
654	Vesicovaginal Fistula	1.6%
655	Gait Apraxia	1.5%
656	Putaminal Hemorrhage	1.5%
657	Dementia, Vascular	1.4%
658	Reflex, Abnormal	1.4%
659	Hyporeflexia	1.4%
660	Hyperreflexia	1.4%
661	Birth Weight	1.4%
662	Vision Disorders	1.4%
663	Metamorphopsia	1.4%
664	Visual Impairment	1.4%
665	Bronchial Fistula	1.4%
666	Metatarsalgia	1.4%
667	Pancreatic Fistula	1.4%
668	Cachexia	1.3%
669	Anisocoria	1.3%
670	Confusion	1.3%
671	Facial paralysis	1.3%
672	Intestinal Fistula	1.3%
673	Lethargy	1.3%
674	Memory Disorders	1.3%
675	Muscle Cramp	1.3%
676	Perceptual Disorders	1.3%
677	Psychomotor Disorders	1.3%
678	Tonic Pupil	1.3%
679	Anhedonia	1.3%
680	Disorientation	1.3%
681	Gastroschisis	1.3%
682	Enterocutaneous Fistula	1.3%
683	Fetal Hypoxia	1.3%
684	Facial Paresis	1.3%
685	Memory Loss	1.3%
686	Hemisensory Neglect	1.3%
687	Dysacusis	1.3%
688	Dyspnea, Paroxysmal	1.3%
689	Mastodynia	1.3%
690	Respiratory Paralysis	1.3%
691	Salivary Gland Fistula	1.3%
692	Chorea	1.3%
693	Cystocele	1.3%
694	Tetany	1.3%
695	Urinary Incontinence	1.3%
696	Breakthrough Pain	1.3%
697	Albuminuria	1.3%
698	Hemoglobinuria	1.3%
699	Umbilical hernia	1.2%
700	Toothache	1.2%
701	Hyperemesis Gravidarum	1.2%
702	Dysgeusia	1.2%
703	Formication	1.2%
704	Hyperalgesia	1.2%
705	Hyperesthesia	1.2%
706	Hypesthesia	1.2%
707	Language Disorders	1.2%
708	Numbness	1.2%
709	Paresthesia	1.2%
710	Paraparesis, Spastic	1.2%
711	Trismus	1.2%
712	Epilepsia Partialis Continua	1.2%
713	Hypogeusia	1.2%
714	Brown-Sequard Syndrome	1.2%
715	Lockjaw	1.2%
716	Allodynia	1.2%
717	Ageusia	1.2%
718	Alice in Wonderland Syndrome	1.2%
719	Catatonia	1.1%
720	Musculoskeletal Pain	1.1%
721	Ophthalmoplegia	1.1%
722	External Ophthalmoplegia	1.1%
723	Aphonia	1.1%
724	Arthralgia	1.1%
725	Hydrops Fetalis	1.1%
726	Polyarthralgia	1.1%
727	Dysphonia	1.1%
728	Cerebrospinal Fluid Otorrhea	1.1%
729	Cerebrospinal Fluid Rhinorrhea	1.1%
730	Fetal Weight	1.1%
731	Obesity	1.1%
732	Agraphia	1%
733	Anomia	1%
734	Cluttering	1%
735	Language Development Disorders	1%
736	Speech Disorders	1%
737	Syncope	1%
738	Stupor	1%
739	Dysgraphia	1%
740	Presyncope	1%
741	Dyslalia	1%
742	Diplopia	1%
743	Muscle Rigidity	1%
744	Muscle Spasticity	1%
745	Scotoma	1%
746	Photophobia	1%
747	Cogwheel Rigidity	1%
748	Hemifacial Spasm	1%
749	Amaurosis	1%
750	Blindness	1%
751	Nuchal Rigidity	1%
752	Angina Pectoris	1%
753	Agnosia	1%
754	Apraxias	1%
755	Hallucinations	1%
756	Hemianopsia	1%
757	Hyperacusis	1%
758	Tinnitus	1%
759	Visual Agnosia	1%
760	Anosognosia	1%
761	Wernicke-Korsakoff Syndrome	1%
762	Phonophobia	1%
763	Hearing Loss	1%
764	Cerebellar Ataxia	1%
765	Torticollis	1%
766	Sciatica	1%
767	Urge Incontinence	1%
768	Tardive Dyskinesia	1%
769	Vocal Cord Paralysis	1%
770	Urinary Bladder Fistula	0.9%
771	Tinea Pedis	0.9%
772	Aphasia	0.9%
773	Articulation Disorders	0.9%
774	Echolalia	0.9%
775	Stuttering	0.9%
776	Dysphasia	0.9%
777	Dysarthria	0.9%
778	Dyskinesia, Drug-Induced	0.8%
779	Amblyopia	0.8%
780	Horner Syndrome	0.8%
781	Color blindness	0.8%
782	Alcohol Withdrawal Seizures	0.8%
783	Arteriovenous fistula	0.8%
784	Rectal Fistula	0.8%
785	Anal Fistula	0.8%
786	Amaurosis Fugax	0.8%
787	Blindness, Cortical	0.8%
788	Shoulder Pain	0.8%
789	Angina, Unstable	0.8%
790	Deafness	0.8%
791	Hearing Loss, Sudden	0.8%
792	Gerstmann Syndrome	0.8%
793	Hearing Loss, Bilateral	0.8%
794	Hearing Loss, High-Frequency	0.8%
795	Hearing Loss, Mixed Conductive-Sensorineural	0.8%
796	Prosopagnosia	0.8%
797	Apraxia, Ideomotor	0.8%
798	Persistent Vegetative State	0.8%
799	Charles Bonnet Syndrome	0.8%
800	Hearing Loss, Unilateral	0.8%
801	Complete Hearing Loss	0.8%
802	Alien Hand Syndrome	0.8%
803	Deaf Mutism	0.8%
804	Pediatric Obesity	0.8%
805	Angina Pectoris, Variant	0.7%
806	Akathisia, Drug-Induced	0.7%
807	Kidney Calculi	0.7%
808	Ureteral Calculi	0.7%
809	Myalgia	0.7%
810	Ophthalmoplegic Migraine	0.6%
811	Progressive supranuclear palsy	0.5%
812	Kearns-Sayre syndrome	0.3%

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