MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Sufentanil

(GGCSSNBKKAUURC-UHFFFAOYSA-N)

Structure

SMILES: COCC1(CCN(CC1)CCc1cccs1)N(c1ccccc1)C(=O)CC
Type(s): Approved; Investigational
ATC code(s): N01AH03
Molecular Formula:: C22H30N2O2S
Molecular Weight:: 386.551
Log P:: 4.1527
Hydrogen Bond Acceptor:: 5
Hydrogen Bond Donor:: 0
TPSA:: 61.02
CAS Number(s):: 56030-54-7

Synonym(s)

Sufentanil

R-30730

Sufenta

Sufentanil Citrate

Sufentanil Curasan

Sufentanil-Hameln

Sufentanil-Ratiopharm

Sulfentanil

Sulfentanyl

10.

Citrate, Sufentanil

11.

Curasan, Sufentanil

12.

R 30730

13.

R30730

14.

Sufentanil Hameln

15.

Sufentanil Ratiopharm

16.

SufentanilHameln

17.

SufentanilRatiopharm

External Link(s)

MeSH	D017409
PubChem Compound	41693
BindingDB	50012490 94503
ChEBI	9316
CHEMBL	CHEMBL658
DrugBank	DB00708
DrugCentral	2491
IUPHAR/BPS Guide to PHARMACOLOGY	3534
KEGG	cpd:C08022 dr:D05938
Therapeutic Target Database	D0D8DD
ZINC	538386

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abdominal Compartment Syndrome		OFFSIDES
2	Acidosis		OFFSIDES
3	Acute respiratory failure		OFFSIDES
4	Alanine Aminotransferase Increased		OFFSIDES
5	Allergy test positive		OFFSIDES
6	Alveolitis		OFFSIDES
7	Anaphylactic shock		SIDER
8	Angioedema		OFFSIDES
9	Angle Closure Glaucoma		OFFSIDES
10	Anisocoria		OFFSIDES
11	Anoxia		OFFSIDES
12	Anoxic Encephalopathy		OFFSIDES
13	Anticholinergic Syndrome		OFFSIDES
14	Anuria		OFFSIDES
15	Aortic bruit		OFFSIDES
16	Aphasia	10781475 12694015	CTD
17	Apnea	View details 2311153 2525674 7826792 9818112 15196117	CTD OFFSIDES
18	Arteriovenous fistula thrombosis		OFFSIDES
19	Atrial Flutter		OFFSIDES
20	Atrial tachycardia		OFFSIDES
21	Avascular necrosis		OFFSIDES
22	Bifascicular block		OFFSIDES
23	Bile Duct Stenosis		OFFSIDES
24	Blood creatine phosphokinase MB increased		OFFSIDES
25	Blood creatine phosphokinase increased		OFFSIDES
26	Blood lactate dehydrogenase increased		OFFSIDES
27	Blood pressure immeasurable		OFFSIDES
28	Body Temperature		OFFSIDES
29	Bradycardia	View details 1983399 2524285 2870669 2948427 7906108 9856707 15470169 20077594	CTD OFFSIDES SIDER
30	Brain Death		OFFSIDES
31	Brain Hypoxia		OFFSIDES
32	Bronchial Obstruction		OFFSIDES
33	Bronchoalveolar Lavage		OFFSIDES
34	Bronchopneumonia		OFFSIDES
35	Bronchospasm		SIDER
36	Bulbar palsy		OFFSIDES
37	Cardiac Arrest		SIDER
38	Cardiac Tamponade		OFFSIDES
39	Cardiac procedure complication		OFFSIDES
40	Cardiovascular insufficiency		OFFSIDES
41	Carotid bruit		OFFSIDES
42	Catheter related infection		OFFSIDES
43	Cauda Equina Syndrome		OFFSIDES
44	Cell Death		OFFSIDES
45	Chills		SIDER
46	Coagulation factor VIII level decreased		OFFSIDES
47	Complications of maternal exposure to therapeutic drugs		OFFSIDES
48	Contracture		OFFSIDES
49	Cyanosis		OFFSIDES
50	Cytolytic hepatitis		OFFSIDES
51	Demyelination		OFFSIDES
52	Dermatitis		SIDER
53	Dermatomyositis		OFFSIDES
54	Disseminated Intravascular Coagulation		OFFSIDES
55	Diverticulosis		OFFSIDES
56	Dizziness	8457049 11782332 11981144	CTD SIDER
57	Drug exposure during pregnancy		OFFSIDES
58	Drug level fluctuating		OFFSIDES
59	Duodenal atresia		OFFSIDES
60	Electrocardiogram repolarisation abnormality		OFFSIDES
61	Embolism		OFFSIDES
62	Encephalitis		OFFSIDES
63	End-tidal CO2 decreased		OFFSIDES
64	Enterococcal infection		OFFSIDES
65	Enterococcal sepsis		OFFSIDES
66	Eosinophilic myocarditis		OFFSIDES
67	Epilepsy		OFFSIDES
68	Erythema Multiforme		OFFSIDES
69	Erythema		OFFSIDES SIDER
70	Euphoric mood		SIDER
71	Excessive sexual fantasies		OFFSIDES
72	Feeling Cold		OFFSIDES
73	Feeling abnormal		SIDER
74	Gallbladder necrosis		OFFSIDES
75	Gamma-Glutamyltransferase Increased		OFFSIDES
76	Gangrene		OFFSIDES
77	General physical health deterioration		OFFSIDES
78	Globulinuria		OFFSIDES
79	Granulocytosis		OFFSIDES
80	Haemoconcentration		OFFSIDES
81	Headache		SIDER
82	Hepatitis B positive		OFFSIDES
83	Hepatitis C		OFFSIDES
84	Hepatitis		OFFSIDES
85	Histamine level increased		OFFSIDES
86	Histiocytosis haematophagic		OFFSIDES
87	Hydrocephalus		OFFSIDES
88	Hyperalgesia	9100184 20031953 20077594	CTD
89	Hypercapnia		OFFSIDES
90	Hypersensitivity		SIDER
91	Hyporeflexia		OFFSIDES
92	Hypotension	View details 2524285 2939780 2955719 8872691 9717591 9972757 11981144 15055890 19189982 20077594	CTD SIDER
93	Hypoxia		OFFSIDES
94	Iatrogenic injury		OFFSIDES
95	Incorrect drug administration rate		OFFSIDES
96	Incorrect route of drug administration		OFFSIDES
97	Infusion site nerve damage		OFFSIDES
98	Injection site pain		SIDER
99	Injection site thrombosis		OFFSIDES
100	Iridocyclitis		OFFSIDES
101	Kidney Failure		OFFSIDES
102	Labor Pain	View details 7618720 8872691 9818112 9840847 9972757 10741192 10781475 10839903 10989857 11981144 15055890 17935933 19329014	CTD
103	Large intestine perforation		OFFSIDES
104	Laryngospasm		SIDER
105	Leukoencephalopathy		OFFSIDES
106	Lipase		OFFSIDES
107	Livedo Reticularis		OFFSIDES
108	Lymphocele		OFFSIDES
109	Mediastinoscopy		OFFSIDES
110	Medical device complication		OFFSIDES
111	Megacolon		OFFSIDES
112	Mental disorders	10781475	CTD
113	Metabolic acidosis		OFFSIDES
114	Monocytosis		OFFSIDES
115	Mononucleosis syndrome		OFFSIDES
116	Monoplegia		OFFSIDES
117	Muscle Rigidity	View details 2531560 2932985 8311329 9407685	CTD SIDER
118	Muscle necrosis		OFFSIDES
119	Myocardial Ischemia	1824584 1826989	CTD
120	Myoclonus	View details 2524285 2531560 2959172 12694150	CTD
121	Myoglobin blood increased		OFFSIDES
122	Nausea	10839903 11981144 15055890	CTD SIDER
123	Nodule		OFFSIDES
124	Oliguria		OFFSIDES
125	Ophthalmoplegia		OFFSIDES
126	Oral polypectomy		OFFSIDES
127	Oxygen consumption increased		OFFSIDES
128	PROTHROMBIN TIME		OFFSIDES
129	Pain, Postoperative	View details 1385919 2888421 7826792 8457049 9407685 9570608 19189982 20031953	CTD
130	Pain	View details 7892029 8702050 9249116 9717591 18008122	CTD
131	Pancreatitis		OFFSIDES
132	Paraparesis		OFFSIDES
133	Paraplegia		OFFSIDES
134	Pathogen resistance		OFFSIDES
135	Peripartum cardiomyopathy		OFFSIDES
136	Piloerection		OFFSIDES
137	Pityriasis		OFFSIDES
138	Plasmin increased		OFFSIDES
139	Pneumothorax		OFFSIDES
140	Polyuria		OFFSIDES
141	Post procedural complication		OFFSIDES
142	Postoperative Nausea and Vomiting	19189982	CTD
143	Procedural complication		OFFSIDES
144	Product contamination		OFFSIDES
145	Propofol Infusion Syndrome		OFFSIDES
146	Protein total increased		OFFSIDES
147	Prothrombin time ratio decreased		OFFSIDES
148	Pruritus	View details 9667296 10741192 10839903 11981144 12694015 15055890 19189982	CTD SIDER
149	Pulmonary Hypertension		OFFSIDES
150	Pulmonary artery thrombosis		OFFSIDES
151	Pulmonary function test decreased		SIDER
152	Pulmonary sepsis		OFFSIDES
153	Quadriparesis		OFFSIDES
154	Quadriplegia		OFFSIDES
155	Rales		OFFSIDES
156	Respiratory Depression		SIDER
157	Respiratory Failure		OFFSIDES
158	Respiratory Insufficiency	2311153 2932985 9249116	CTD
159	Rhabdomyolysis		OFFSIDES
160	Rhinitis		OFFSIDES
161	Seizures	2953271 2964214	CTD
162	Sensation Disorders	7486165	CTD
163	Septic Shock		OFFSIDES
164	Shivering		SIDER
165	Sick Sinus Syndrome	2065427	CTD
166	Sinus Arrest, Cardiac	1983399	CTD
167	Sjogren's Syndrome		OFFSIDES
168	Skin test negative		OFFSIDES
169	Skin test positive		OFFSIDES
170	Somnolence		SIDER
171	Spasm	8669697	CTD
172	Splenectomy		OFFSIDES
173	Splenic Infarction		OFFSIDES
174	Status Epilepticus		OFFSIDES
175	Stevens-Johnson Syndrome		OFFSIDES
176	Stiff-Person Syndrome	7618699	CTD
177	Stress ulcer		OFFSIDES
178	Substance Withdrawal Syndrome	10583354 15714323	CTD
179	Superficial Thrombophlebitis		OFFSIDES
180	Superinfection lung		OFFSIDES
181	Systolic hypertension		OFFSIDES
182	Tachycardia, Ventricular	18334037	CTD
183	Tachycardia		SIDER
184	Thoracotomy		OFFSIDES
185	Transaminases increased		OFFSIDES
186	Tremor	12694015	CTD
187	Trismus	9407685	CTD
188	Troponin I increased		OFFSIDES
189	Troponin T		OFFSIDES
190	Troponin increased		OFFSIDES
191	Tryptase increased		OFFSIDES
192	Ureterostomy site discomfort		OFFSIDES
193	Urinary Incontinence		SIDER
194	Urinary Retention	9031957	CTD SIDER
195	Uterine atrophy		OFFSIDES
196	Vasoplegia syndrome		OFFSIDES
197	Vasospasm		OFFSIDES
198	Venous thrombosis limb		OFFSIDES
199	Ventricular Fibrillation	18334037	CTD OFFSIDES
200	Ventricular hypokinesia		OFFSIDES
201	Vomiting	8457049 10839903	CTD SIDER
202	Wound Infection		OFFSIDES

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