MetaADEDB 2.0 @ LMMD
Bupivacaine
(LEBVLXFERQHONN-UHFFFAOYSA-N)
Structure
SMILES
CCCCN1CCCCC1C(=O)Nc1c(C)cccc1C
Type(s)
Approved; Investigational
ATC code(s)
N01BB01; N01BB51
Molecular Formula:
C18H28N2O
Molecular Weight:
288.428
Log P:
3.9074
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
32.34
CAS Number(s):
2180-92-9; 38396-39-3
Synonym(s)
1.
Bupivacaine
2.
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
3.
Bupivacain Janapharm
4.
Bupivacain-RPR
5.
Bupivacaina Braun
6.
Bupivacaine Anhydrous
7.
Bupivacaine Carbonate
8.
Bupivacaine Hydrochloride
9.
Bupivacaine Monohydrochloride, Monohydrate
10.
Buvacaina
11.
Carbostesin
12.
Dolanaest
13.
Marcain
14.
Marcaine
15.
Sensorcaine
16.
Svedocain Sin Vasoconstr
17.
Bupivacain RPR
External Link(s)
MeSHD002045
PubChem Compound2474
BindingDB50350790
ChEBI77431
CHEMBLCHEMBL1098
DrugBankDB00297
DrugCentral432
IUPHAR/BPS Guide to PHARMACOLOGY2397
KEGGcpd:C07529
dr:D07552
Therapeutic Target DatabaseD0A0FL
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 693
Canada Vigilance: 57		Canada Vigilance
OFFSIDES
US FAERS
2Drug effect incompleteFAERS: 47US FAERS
3Product quality issueFAERS: 36
Canada Vigilance: 1		Canada Vigilance
US FAERS
4PainFAERS: 34

View details

843977
1218181
1847291
2006747
2025473
3407988
3662064
6536516
6784596
7091617
7605766
7618726
7947427
8034840
9389845
9414063
9570604
9717591
10070450
10445770
10492406
10522581
10825327
11473881
11576059
12707139
15041598
15166572
15220782
16037173
16275412
17137669
19386869
19469101
19897799
 		CTD
OFFSIDES
SIDER
US FAERS
5Cardiac ArrestFAERS: 30
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
6Drug effect delayedFAERS: 30OFFSIDES
US FAERS
7HypotensionFAERS: 26
Canada Vigilance: 2

View details

352187
878830
1148075
1340763
1385919
1897763
2487666
2511782
2594614
3425883
3515598
3729024
3749544
3963429
6362693
6465596
6536516
6837232
7618720
7716603
8010419
8053587
8067230
8342839
8489980
8590509
8872691
8881615
8895282
8956398
9452848
9689277
9717591
9750602
9778009
9972757
10638892
10995146
11529341
12025250
12439553
12932066
15055890
15766337
15957693
16113981
16226864
16278496
16786914
16834790
16859572
17319428
17427526
17461537
17646515
17892610
18282259
18399341
19232937
19469101
19686477
19843797
19849674
20527340
20644295
 		CTD
SIDER
Canada Vigilance
US FAERS
8BradycardiaFAERS: 21

View details

1210484
1340763
1567039
2594614
3350328
3749544
3749546
3963429
6837232
7877067
7908178
8956398
9952103
10193283
10638917
12025250
14984867
16834790
17646515
17697771
18282259
20112819
 		CTD
SIDER
US FAERS
9Pharmaceutical product complaintFAERS: 20OFFSIDES
US FAERS
10Post procedural complicationFAERS: 17OFFSIDES
US FAERS
11Cauda Equina SyndromeFAERS: 16OFFSIDES
SIDER
US FAERS
12Toxicity to various agentsFAERS: 15
Canada Vigilance: 4		Canada Vigilance
SIDER
US FAERS
13DizzinessFAERS: 132006745
6613504
9175963		CTD
SIDER
US FAERS
14Musculoskeletal PainFAERS: 13OFFSIDES
US FAERS
15treatment failureFAERS: 12OFFSIDES
US FAERS
16Joint Range of Motion DecreasedFAERS: 11OFFSIDES
US FAERS
17NauseaFAERS: 11

View details

3515598
8489980
8881615
9836029
10193215
10447906
10520911
15025617
15055890
17646515
19469101
19686477
 		CTD
SIDER
US FAERS
18ArthralgiaFAERS: 10SIDER
US FAERS
19Medication ErrorFAERS: 10
Canada Vigilance: 1		Canada Vigilance
US FAERS
20Respiratory arrestFAERS: 10SIDER
US FAERS
21SwellingFAERS: 10
Canada Vigilance: 1		Canada Vigilance
US FAERS
22Inadequate analgesiaFAERS: 9US FAERS
23Incorrect product storageFAERS: 9US FAERS
24Product measured potency issueFAERS: 9US FAERS
25AstheniaFAERS: 8OFFSIDES
SIDER
US FAERS
26DiplopiaFAERS: 8OFFSIDES
SIDER
US FAERS
27CyanosisFAERS: 7US FAERS
28Expired product administeredFAERS: 7US FAERS
29Musculoskeletal discomfortFAERS: 7OFFSIDES
SIDER
US FAERS
30Pulmonary EmbolismFAERS: 7US FAERS
31AnxietyFAERS: 6
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
32Drug exposure during pregnancyFAERS: 6OFFSIDES
US FAERS
33DysgeusiaFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
34MeningitisFAERS: 610480179
19653822
20306069		CTD
SIDER
US FAERS
35Muscle RigidityFAERS: 69175963CTD
US FAERS
36Product use issueFAERS: 6US FAERS
37TachycardiaFAERS: 63689617
3749544
18942254		CTD
SIDER
US FAERS
38Ventricular FibrillationFAERS: 6
Canada Vigilance: 3

View details

1489030
1897763
2511782
2790295
3521804
3632138
9648339
9814406
 		CTD
SIDER
Canada Vigilance
US FAERS
39VomitingFAERS: 6

View details

3749544
8881615
10193215
19469101
 		CTD
SIDER
US FAERS
40nervous system disorderFAERS: 6SIDER
US FAERS
41Activities of daily living impairedFAERS: 5OFFSIDES
US FAERS
42Anaphylactic shockFAERS: 5SIDER
US FAERS
43ArthropathyFAERS: 5US FAERS
44Drug administration errorFAERS: 5US FAERS
45Drug toxicityFAERS: 5OFFSIDES
SIDER
US FAERS
46HypersensitivityFAERS: 5SIDER
US FAERS
47Muscle SpasticityFAERS: 5US FAERS
48Procedural complicationFAERS: 5OFFSIDES
US FAERS
49Respiratory FailureFAERS: 5OFFSIDES
SIDER
US FAERS
50StrabismusFAERS: 511641647CTD
US FAERS
51Urinary IncontinenceFAERS: 58437068
17000845
17960002		CTD
SIDER
US FAERS
52AgitationFAERS: 4SIDER
US FAERS
53AphoniaFAERS: 4OFFSIDES
US FAERS
54Complications of maternal exposure to therapeutic drugsFAERS: 4OFFSIDES
US FAERS
55Depressed Level of ConsciousnessFAERS: 4SIDER
US FAERS
56Device FailureFAERS: 4US FAERS
57FatigueFAERS: 4US FAERS
58Feeling of body temperature changeFAERS: 4US FAERS
59HeadacheFAERS: 4
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
60InfectionFAERS: 4SIDER
US FAERS
61Joint injuryFAERS: 4OFFSIDES
US FAERS
62LethargyFAERS: 4OFFSIDES
SIDER
US FAERS
63MonoplegiaFAERS: 4OFFSIDES
SIDER
US FAERS
64Myocardial InfarctionFAERS: 417461537CTD
US FAERS
65No adverse eventFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
66ParaplegiaFAERS: 421030892CTD
OFFSIDES
SIDER
US FAERS
67Sensorimotor disorderFAERS: 4OFFSIDES
US FAERS
68ShockFAERS: 4SIDER
US FAERS
69Skin reactionFAERS: 4US FAERS
70SyncopeFAERS: 4SIDER
US FAERS
71Unresponsive to stimuliFAERS: 4OFFSIDES
US FAERS
72Acute kidney injuryFAERS: 3US FAERS
73Atrial FibrillationFAERS: 3US FAERS
74Back PainFAERS: 37497563CTD
SIDER
US FAERS
75ClonusFAERS: 3US FAERS
76DiplegiaFAERS: 3SIDER
US FAERS
77DysuriaFAERS: 3US FAERS
78ErythemaFAERS: 3SIDER
US FAERS
79HypercapniaFAERS: 3OFFSIDES
SIDER
US FAERS
80Inappropriate schedule of product administrationFAERS: 3US FAERS
81Incorrect dose administeredFAERS: 3US FAERS
82Injection site painFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
83Maternal exposure during pregnancyFAERS: 3US FAERS
84NecrosisFAERS: 311565617
18658020		CTD
US FAERS
85Nerve injuryFAERS: 3US FAERS
86OverdoseFAERS: 3US FAERS
87PolyneuropathyFAERS: 3US FAERS
88Poor quality drug administeredFAERS: 3US FAERS
89Post lumbar puncture syndromeFAERS: 3OFFSIDES
US FAERS
90Pre-EclampsiaFAERS: 315310446CTD
OFFSIDES
US FAERS
91PresyncopeFAERS: 3US FAERS
92Product label confusionFAERS: 3US FAERS
93Product label issueFAERS: 3US FAERS
94Product substitution issueFAERS: 3US FAERS
95Rash erythematousFAERS: 3US FAERS
96Respiratory distressFAERS: 3US FAERS
97TremorFAERS: 3
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
98Urinary tract infectionFAERS: 3SIDER
US FAERS
99Wound dehiscenceFAERS: 3OFFSIDES
US FAERS
100AbasiaFAERS: 2US FAERS
101Abdominal PainFAERS: 2SIDER
US FAERS
102Abdominal tendernessFAERS: 2US FAERS
103Accidental overdoseFAERS: 2OFFSIDES
US FAERS
104Apparent life threatening eventFAERS: 2OFFSIDES
US FAERS
105ArachnoiditisFAERS: 2OFFSIDES
SIDER
US FAERS
106Atrial FlutterFAERS: 2US FAERS
107Blood pH decreasedFAERS: 2OFFSIDES
US FAERS
108BronchospasmFAERS: 2SIDER
US FAERS
109Burning sensationFAERS: 2US FAERS
110CardiomegalyFAERS: 2US FAERS
111CardiotoxicityFAERS: 224438483CTD
US FAERS
112Cell DeathFAERS: 2OFFSIDES
US FAERS
113CellulitisFAERS: 2US FAERS
114Culture wound positiveFAERS: 2OFFSIDES
US FAERS
115DiscomfortFAERS: 2US FAERS
116Feeling abnormalFAERS: 2SIDER
US FAERS
117Flank PainFAERS: 2US FAERS
118Gaze palsyFAERS: 2OFFSIDES
US FAERS
119HypoxiaFAERS: 27059040CTD
OFFSIDES
US FAERS
120Impaired work abilityFAERS: 2US FAERS
121Implant site infectionFAERS: 2US FAERS
122Incision site painFAERS: 2OFFSIDES
US FAERS
123Injection site erythemaFAERS: 2US FAERS
124Intervertebral Disc DegenerationFAERS: 2US FAERS
125Joint swellingFAERS: 2US FAERS
126Limb discomfortFAERS: 2US FAERS
127Limb injuryFAERS: 2OFFSIDES
US FAERS
128Mental status changesFAERS: 2OFFSIDES
US FAERS
129MyalgiaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
130Nerve root lesionFAERS: 2US FAERS
131OsteomyelitisFAERS: 2OFFSIDES
US FAERS
132PO2 decreasedFAERS: 2US FAERS
133PalpitationsFAERS: 2SIDER
US FAERS
134Phantom painFAERS: 2US FAERS
135Procedural hypotensionFAERS: 2OFFSIDES
SIDER
US FAERS
136Product barcode issueFAERS: 2US FAERS
137PruritusFAERS: 2
Canada Vigilance: 1

View details

8053587
8067230
8087910
8214466
9620513
9836029
10193215
10447906
10520911
11359592
15025617
15055890
17697771
 		CTD
SIDER
Canada Vigilance
US FAERS
138Pulmonary InfarctionFAERS: 2OFFSIDES
US FAERS
139RadiculopathyFAERS: 29794061
11899459		CTD
US FAERS
140Seizure like phenomenaFAERS: 2US FAERS
141Sinus TachycardiaFAERS: 2US FAERS
142Skin test positiveFAERS: 2OFFSIDES
US FAERS
143Staphylococcal abscessFAERS: 2OFFSIDES
US FAERS
144Suspected transmission of an infectious agent via productFAERS: 2US FAERS
145SynovitisFAERS: 2OFFSIDES
US FAERS
146Thermal burnFAERS: 2US FAERS
147Unmasking of previously unidentified diseaseFAERS: 2US FAERS
148Vascular occlusionFAERS: 2US FAERS
149VertigoFAERS: 2US FAERS
150Wrong drug administeredFAERS: 2US FAERS
151Abdominal AbscessFAERS: 1US FAERS
152AbscessFAERS: 1US FAERS
153Accidental exposureFAERS: 1US FAERS
154AcidosisFAERS: 17059040CTD
SIDER
US FAERS
155Adverse eventFAERS: 1US FAERS
156Alanine Aminotransferase IncreasedFAERS: 1SIDER
US FAERS
157Allergy test positiveFAERS: 1OFFSIDES
US FAERS
158Altered state of consciousnessFAERS: 1US FAERS
159AmnesiaFAERS: 1US FAERS
160AnalgesiaFAERS: 1OFFSIDES
US FAERS
161Anaphylactoid ReactionFAERS: 1SIDER
US FAERS
162Anastomotic LeakFAERS: 1OFFSIDES
US FAERS
163Angina PectorisFAERS: 1US FAERS
164AnhedoniaFAERS: 1US FAERS
165AnorexiaFAERS: 1US FAERS
166AphasiaFAERS: 110781475CTD
US FAERS
167Apparent deathFAERS: 1US FAERS
168Arterial InjuryFAERS: 1US FAERS
169Aspartate Aminotransferase IncreasedFAERS: 1SIDER
US FAERS
170AtelectasisFAERS: 1OFFSIDES
US FAERS
171Atrioventricular BlockFAERS: 118282259CTD
SIDER
US FAERS
172Bacterial test positiveFAERS: 1US FAERS
173BedriddenFAERS: 1US FAERS
174Blood albumin decreasedFAERS: 1US FAERS
175Blood potassium increasedFAERS: 1OFFSIDES
US FAERS
176Blood pressure fluctuationFAERS: 1US FAERS
177Blood pressure immeasurableFAERS: 1OFFSIDES
US FAERS
178Brain stem syndromeFAERS: 1OFFSIDES
US FAERS
179BursitisFAERS: 1OFFSIDES
US FAERS
180Cartilage injuryFAERS: 1OFFSIDES
US FAERS
181Catheter related complicationFAERS: 1OFFSIDES
US FAERS
182Cerebrovascular accidentFAERS: 1US FAERS
183Cervical myelopathyFAERS: 1US FAERS
184Chest PainFAERS: 1US FAERS
185Chest discomfortFAERS: 1US FAERS
186ChillsFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
187Circumstance or information capable of leading to medication errorFAERS: 1OFFSIDES
US FAERS
188Cold sweatFAERS: 1SIDER
US FAERS
189ConstipationFAERS: 1SIDER
US FAERS
190CryingFAERS: 1US FAERS
191DeafnessFAERS: 1US FAERS
192Deep Vein ThrombosisFAERS: 1US FAERS
193Device malfunctionFAERS: 1OFFSIDES
US FAERS
194Diabetes MellitusFAERS: 1US FAERS
195Drug screen positiveFAERS: 1US FAERS
196DysgraphiaFAERS: 1US FAERS
197DystoniaFAERS: 1US FAERS
198EcchymosisFAERS: 1US FAERS
199Economic problemFAERS: 1OFFSIDES
US FAERS
200Electrocardiogram abnormalFAERS: 1SIDER
US FAERS
201Emotional distressFAERS: 1US FAERS
202EncephalitisFAERS: 1US FAERS
203Expired drug administeredFAERS: 1US FAERS
204Extra dose administeredFAERS: 1US FAERS
205ExtravasationFAERS: 1SIDER
US FAERS
206Extremity necrosisFAERS: 1US FAERS
207FlushingFAERS: 1SIDER
US FAERS
208FormicationFAERS: 1OFFSIDES
US FAERS
209HemiparesisFAERS: 1US FAERS
210HemiplegiaFAERS: 1US FAERS
211HydrocephalusFAERS: 1OFFSIDES
US FAERS
212HypokinesiaFAERS: 1SIDER
US FAERS
213HyporeflexiaFAERS: 1OFFSIDES
US FAERS
214HypoventilationFAERS: 1US FAERS
215Iatrogenic injuryFAERS: 1OFFSIDES
US FAERS
216Impaired driving abilityFAERS: 1US FAERS
217Implant site extravasationFAERS: 1US FAERS
218Incision site erythemaFAERS: 1US FAERS
219Incorrect drug dosage form administeredFAERS: 1US FAERS
220Incorrect route of drug administrationFAERS: 1OFFSIDES
US FAERS
221IndurationFAERS: 1US FAERS
222InflammationFAERS: 118165598CTD
US FAERS
223Infusion site indurationFAERS: 1US FAERS
224Infusion site painFAERS: 1US FAERS
225Infusion site swellingFAERS: 1US FAERS
226Injection Site ReactionFAERS: 1US FAERS
227Injection site infectionFAERS: 1OFFSIDES
US FAERS
228Injection site necrosisFAERS: 1US FAERS
229Injection site nerve damageFAERS: 1US FAERS
230Intentional drug misuseFAERS: 1US FAERS
231Internal injuryFAERS: 1US FAERS
232Joint stiffnessFAERS: 1US FAERS
233Joint vibrationFAERS: 1US FAERS
234Maternal exposure during deliveryFAERS: 1US FAERS
235Medical device complicationFAERS: 1OFFSIDES
US FAERS
236Memory impairmentFAERS: 1US FAERS
237Mental impairmentFAERS: 1US FAERS
238Migration of implantFAERS: 1OFFSIDES
US FAERS
239Multiple SclerosisFAERS: 1US FAERS
240Muscle strainFAERS: 1US FAERS
241Musculoskeletal stiffnessFAERS: 1OFFSIDES
SIDER
US FAERS
242MydriasisFAERS: 1US FAERS
243MyoclonusFAERS: 114597801
17602048
20332743		CTD
US FAERS
244Neck PainFAERS: 1SIDER
US FAERS
245Nerve BlockFAERS: 1OFFSIDES
US FAERS
246NervousnessFAERS: 1SIDER
US FAERS
247Neuroleptic Malignant SyndromeFAERS: 1US FAERS
248Oropharyngeal painFAERS: 1US FAERS
249PCO2 decreasedFAERS: 1US FAERS
250PCO2 increasedFAERS: 1US FAERS
251Painful response to normal stimuliFAERS: 1OFFSIDES
US FAERS
252ParaparesisFAERS: 1OFFSIDES
US FAERS
253ParesisFAERS: 1

View details

843977
4057027
8074401
16786914
16834790
17961837
 		CTD
SIDER
US FAERS
254Peripheral nerve palsyFAERS: 1US FAERS
255PhotophobiaFAERS: 1US FAERS
256Phrenic nerve paralysisFAERS: 1US FAERS
257Pilonidal sinus repairFAERS: 1US FAERS
258PneumoperitoneumFAERS: 1US FAERS
259Post procedural infectionFAERS: 1US FAERS
260Post procedural painFAERS: 1OFFSIDES
US FAERS
261Postoperative adhesionFAERS: 1US FAERS
262Postoperative wound complicationFAERS: 1US FAERS
263PosturingFAERS: 1US FAERS
264PregnancyFAERS: 1US FAERS
265PriapismFAERS: 1SIDER
US FAERS
266Procedural dizzinessFAERS: 1US FAERS
267Product container seal issueFAERS: 1US FAERS
268Product use complaintFAERS: 1US FAERS
269Productive CoughFAERS: 1US FAERS
270Pulmonary congestionFAERS: 1US FAERS
271Pulmonary thrombosisFAERS: 1OFFSIDES
US FAERS
272RestlessnessFAERS: 1US FAERS
273Retrograde amnesiaFAERS: 1OFFSIDES
US FAERS
274RhabdomyolysisFAERS: 1US FAERS
275Rotator cuff syndromeFAERS: 1US FAERS
276Sacral painFAERS: 1US FAERS
277ScreamingFAERS: 1US FAERS
278Serotonin SyndromeFAERS: 1US FAERS
279Sinus headacheFAERS: 1US FAERS
280Skin UlcerFAERS: 1US FAERS
281SnoringFAERS: 1OFFSIDES
US FAERS
282Soft Tissue InfectionFAERS: 1US FAERS
283SomnolenceFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
284SpondylosisFAERS: 1US FAERS
285StridorFAERS: 1OFFSIDES
US FAERS
286Supraventricular tachycardiaFAERS: 1US FAERS
287Therapeutic product ineffectiveFAERS: 1US FAERS
288Therapy non-responderFAERS: 1US FAERS
289TinnitusFAERS: 16613504CTD
SIDER
US FAERS
290TransplantFAERS: 1US FAERS
291Ventricular DysfunctionFAERS: 1US FAERS
292Ventricular arrhythmiaFAERS: 1SIDER
US FAERS
293Visceral congestionFAERS: 1US FAERS
294Visual ImpairmentFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
295Vocal Cord ParalysisFAERS: 111576059CTD
US FAERS
296Wound necrosisFAERS: 1US FAERS
297intensive careFAERS: 1US FAERS
298muscle injuryFAERS: 1OFFSIDES
US FAERS
299Abdominal Compartment SyndromeOFFSIDES
300Abdominal discomfortOFFSIDES
301Acquired diaphragmatic eventrationOFFSIDES
302ActinomycosisOFFSIDES
303Acute psychosisOFFSIDES
304Adjustment disorder with depressed moodOFFSIDES
305Air EmbolismOFFSIDES
306Alopecia effluviumOFFSIDES
307AngioedemaSIDER
308AnhidrosisOFFSIDES
309Anterior Spinal Artery SyndromeSIDER
310Anticholinergic SyndromeOFFSIDES
311Apnea

View details

1595917
2065423
2253300
2331071
6496968
8117636
9818112
11172519
12358663
18420881
19897799
 		CTD
OFFSIDES
312Arthropod biteOFFSIDES
313Artificial crown procedureOFFSIDES
314AsbestosisOFFSIDES
315Aseptic MeningitisOFFSIDES
316AsthenopiaOFFSIDES
317AutomatismOFFSIDES
318Blindness, Cortical20068456CTD
319Blood cortisol decreasedOFFSIDES
320Blood creatinine increasedSIDER
321Blood follicle stimulating hormone decreasedOFFSIDES
322Body TemperatureOFFSIDES
323Bone density decreasedOFFSIDES
324Bone lesionOFFSIDES
325Bone swellingOFFSIDES
326Brachial Plexus Neuropathies20971226CTD
327Brain DeathOFFSIDES
328Brain Diseases2031825CTD
329Brain Stem Infarctions10740180CTD
330Brain scan abnormalOFFSIDES
331Breast cancer recurrentOFFSIDES
332Bulbar palsyOFFSIDES
333Bundle-Branch Block3632138CTD
334CNS toxicitySIDER
335Cancer PainOFFSIDES
336Carbon dioxide increasedSIDER
337Cardiovascular Diseases

View details

2604156
3433494
3434894
6679594
7614153
17277955
 		CTD
338Catheter site infectionOFFSIDES
339Catheter site related reactionOFFSIDES
340CausalgiaOFFSIDES
341Cerebellar infarctionOFFSIDES
342Cervical dysplasiaOFFSIDES
343CholangiolitisOFFSIDES
344Cholecystitis infectiveOFFSIDES
345Cholestasis8484525CTD
346ChondromalaciaOFFSIDES
347ChromatopsiaOFFSIDES
348Chronic sinusitisOFFSIDES
349Circumoral paresthesiaSIDER
350Compression fractureOFFSIDES
351Congenital pyelocaliectasisOFFSIDES
352CystOFFSIDES
353DebridementOFFSIDES
354Delayed deliverySIDER
355DemyelinationOFFSIDES
356Dental abscessOFFSIDES
357Dental cariesOFFSIDES
358Denture wearerOFFSIDES
359Depressed moodSIDER
360Device dislocationOFFSIDES
361Device toxicityOFFSIDES
362Disseminated Intravascular CoagulationOFFSIDES
363DrowsinessSIDER
364Drug ToleranceOFFSIDES
365Drug exposure via breast milkOFFSIDES
366Dysarthria9175963
16830158		CTD
SIDER
367DyscheziaOFFSIDES
SIDER
368DyspepsiaSIDER
369Eating disorder symptomOFFSIDES
370EclampsiaOFFSIDES
371Ejection fraction abnormalOFFSIDES
372Electromechanical dissociationOFFSIDES
373End-tidal CO2 decreasedOFFSIDES
374Endodontic procedureOFFSIDES
375Endometrial disorderOFFSIDES
376Enlargement abdomenSIDER
377EpicondylitisOFFSIDES
378Epidural AbscessOFFSIDES
379Euphoric moodSIDER
380ExcoriationOFFSIDES
381ExophthalmosOFFSIDES
382Facial paralysis16275412CTD
383Fasciitis, Plantar17015890CTD
384Fatty LiverOFFSIDES
385Fecal Incontinence11685017CTD
386Feeding disorder neonatalOFFSIDES
387Femoral Neuropathy17543830CTD
388Fetal Diseases3350328
7877067		CTD
389Fever8087910CTD
390Flat affectOFFSIDES
391FlatulenceSIDER
392Foaming at mouthOFFSIDES
393Forceps deliveryOFFSIDES
394Gastric BypassOFFSIDES
395Gastrointestinal PainSIDER
396GlaucomaOFFSIDES
397Graft infectionOFFSIDES
398GranulomaOFFSIDES
399Hearing Loss7880714
9522143		CTD
400Heart Block9667317
19724003		CTD
401Heart Diseases1544204CTD
402Hepatic necrosisOFFSIDES
403HiccoughOFFSIDES
404Histamine level increasedOFFSIDES
405Horner Syndrome

View details

1731557
2006745
3188830
3429196
9583555
10051945
10886715
16859572
17270429
19411261
 		CTD
406HydronephrosisOFFSIDES
407HyperacusisSIDER
408Hyperalgesia11473881
12707139		CTD
409HyperreflexiaOFFSIDES
410HypertrichosisOFFSIDES
411Hypesthesia3515598
6693728		CTD
412HypogeusiaOFFSIDES
413Hypoglossal Nerve DisorderOFFSIDES
414HypophagiaOFFSIDES
415Hypophosphatemia16830158CTD
416Hypotension, Orthostatic8895280
10520911		CTD
417HypotensiveSIDER
418HysterotomyOFFSIDES
419IleusSIDER
420ImmunosuppressionOFFSIDES
421Incision site complicationOFFSIDES
422IncontinenceOFFSIDES
423InfestationSIDER
424Inflammatory painOFFSIDES
425Infusion site massOFFSIDES
426Injection site massOFFSIDES
427Injection site pruritusOFFSIDES
428Injury associated with deviceSIDER
429Intestinal stoma complicationOFFSIDES
430Intracranial HypotensionOFFSIDES
431Intraocular pressure testOFFSIDES
432Jaw lesion excisionOFFSIDES
433Joint InstabilityOFFSIDES
434Joint sprainOFFSIDES
435Labile blood pressureOFFSIDES
436Labor Pain

View details

878830
1218170
1289376
1547044
3289768
3631562
3810235
7386835
7618720
8646094
8872691
9818112
9840847
9972757
10691221
10741192
10781475
10839903
10989857
11412729
11412732
12712868
12933419
14984867
15055890
17697771
17935933
19329014
19377050
20527340
 		CTD
437LaryngospasmSIDER
438LeukocytosisSIDER
439LeukoencephalomyelitisOFFSIDES
440Ligament ruptureOFFSIDES
441LightheadednessSIDER
442Lip exfoliationOFFSIDES
443Loose toothOFFSIDES
444Loss of proprioceptionOFFSIDES
445Low Back Pain7716603CTD
446Lymphocyte transformation test positiveOFFSIDES
447Malignant neoplasm progressionOFFSIDES
448MalnutritionSIDER
449Mastication disorderOFFSIDES
450Mechanical ventilationOFFSIDES
451Meningism1862897CTD
SIDER
452Mental disorders10781475CTD
453Migraine with AuraOFFSIDES
454MonoparesisOFFSIDES
455Muscle Weakness11133631
16830158		CTD
OFFSIDES
456Muscle necrosisOFFSIDES
457Muscle tightnessOFFSIDES
458Muscular Atrophy3407988CTD
459MyelitisOFFSIDES
460Myocardial Ischemia7484038
8974441		CTD
461Myofascial Pain Syndromes19446144CTD
462Neck stiffnessSIDER
463Needle injurySIDER
464Nerve Degeneration19587614CTD
465Neuralgia3188830CTD
466Neurologic reactionSIDER
467NeuromaOFFSIDES
468Neuromyelitis Optica14582781CTD
469NeuropathySIDER
470Nuchal RigiditySIDER
471Numbness of tongueSIDER
472NumbnessSIDER
473Obstetric procedure complicationOFFSIDES
474OphthalmoplegiaOFFSIDES
475OpisthotonusOFFSIDES
476Optic Disc EdemaOFFSIDES
477Oral mucosal erythemaOFFSIDES
478Oropharyngeal spasmOFFSIDES
479Oropharyngeal swellingOFFSIDES
480OsteochondrosisOFFSIDES
481Oxygen supplementationOFFSIDES
482Pain, Intractable15082141CTD
483Pain, Postoperative

View details

1148075
1340763
1385919
1731557
2646848
3422792
4057027
6362693
7618678
7851354
8053587
8067230
8087910
8160955
8214466
8437068
8457049
8484525
8982897
9104516
9352758
9404164
9466101
9542557
9570608
9583555
9613540
9620513
9698952
9836029
9856709
10051932
10215237
10447906
10520911
10691217
10960384
11133631
11359592
11916814
12492791
12538184
12598277
15025617
15310347
15365421
15562083
15564946
15920222
16618299
17961837
18165598
19329015
19411261
20006254
20716080
20833531
20971226
 		CTD
484PallorSIDER
485Paradoxical drug reactionOFFSIDES
486Paresthesia9175963
10853229
11133631		CTD
487ParophthalmiaOFFSIDES
488PeriarthritisOFFSIDES
489Peripartum cardiomyopathyOFFSIDES
490Pharmaceutical product counterfeitOFFSIDES
491Pleural decorticationOFFSIDES
492Polyradiculopathy16301272
16904497		CTD
493Poor personal hygieneOFFSIDES
494Post procedural cellulitisOFFSIDES
495Post procedural fistulaOFFSIDES
496Post procedural swellingSIDER
497Postoperative Complications

View details

8494133
11172519
12358663
17290090
17960002
 		CTD
498Postoperative Nausea and Vomiting

View details

8053587
8087910
9352758
9620513
11359592
15562083
 		CTD
499Primary sequestrumOFFSIDES
500Procedural hypertensionSIDER
501Procedural nauseaSIDER
502Procedural site reactionOFFSIDES
503Product lot number issueCanada Vigilance: 3Canada Vigilance
504PrurigoSIDER
505Psychomotor Agitation12707139CTD
506Pulmonary Edema10954383CTD
507Pulmonary function test decreasedSIDER
508Pupil Disorders20644295CTD
509PurpuraSIDER
510Radial nerve palsyOFFSIDES
511Rectal dischargeSIDER
512Rectal fissureOFFSIDES
513Reflex Sympathetic Dystrophy8484525CTD
514Respiratory DepressionSIDER
515Respiratory Insufficiency1530175
9620513
9698952		CTD
SIDER
516Respiratory Paralysis9699103
11284823		CTD
SIDER
517Retinal vascular occlusionOFFSIDES
518RhonchiOFFSIDES
519Right atrial pressure increasedOFFSIDES
520Salpingo-oophorectomyOFFSIDES
521Sciatic Nerve PalsyOFFSIDES
522Scrotal InfectionOFFSIDES
523Seizures

View details

402143
453563
572181
911057
1119714
1139379
1210484
1340763
1544204
1632544
1897763
1911499
1943471
1958605
2006745
2301766
2511782
3126523
3188822
3337346
3350328
4629566
4753689
6130832
6465582
6465596
6476440
6498581
6612019
6613504
6775560
6829942
7055334
7059040
7091617
7189975
7244932
7394801
7469099
7618678
7618723
7643714
8024139
8231633
8251286
8780283
9814406
9895084
10874433
10899380
14525819
14527371
14980918
15627536
18211454
19299810
19436187
19897799
20122591
 		CTD
524Sensation Disorders7618726
8022625
9522152		CTD
525SequestrectomyOFFSIDES
526SeromaOFFSIDES
527ShiveringSIDER
528Sick Sinus Syndrome2790295CTD
529Sinus bradycardiaSIDER
530Skeletal injuryOFFSIDES
531Skin ErosionOFFSIDES
532Sleep Deprivation9620513CTD
533Slurred speechSIDER
534SneezingSIDER
535Soft Tissue InjuriesOFFSIDES
536Soft tissue necrosisOFFSIDES
537Spinal Cord Diseases15082141CTD
538Spinal Cord Injuries9794061CTD
539Spinal cord paralysisOFFSIDES
540StiffnessSIDER
541Stoma site reactionOFFSIDES
542StuporCanada Vigilance: 1Canada Vigilance
543Sudden Cardiac DeathCanada Vigilance: 2Canada Vigilance
544Surgical vascular shuntOFFSIDES
545SweatingSIDER
546Synovial CystOFFSIDES
547Tachycardia, Ventricular

View details

1340763
1897763
2790295
4025854
6465582
6859605
8238988
8659767
16945804
18299100
19299810
 		CTD
548TachyphylaxisOFFSIDES
549Temperature intoleranceOFFSIDES
550TendinitisOFFSIDES
551TenodesisOFFSIDES
552TensionSIDER
553Therapeutic product effect decreasedCanada Vigilance: 4Canada Vigilance
554Therapeutic product effect delayedCanada Vigilance: 3Canada Vigilance
555Therapeutic product effect incompleteCanada Vigilance: 7Canada Vigilance
556Therapeutic product effect prolongedCanada Vigilance: 1Canada Vigilance
557Therapeutic response delayedCanada Vigilance: 1Canada Vigilance
558ThoracotomyOFFSIDES
559ThrombophlebitisOFFSIDES
560Tooth ExtractionOFFSIDES
561Tooth LossOFFSIDES
562Tooth repairOFFSIDES
563Tracheal StenosisOFFSIDES
564TraumaSIDER
565Trigeminal Nerve DisorderOFFSIDES
566Troponin TOFFSIDES
567Tryptase increasedOFFSIDES
568Umbilical herniaOFFSIDES
569Urinary Bladder Diseases9570608CTD
570Urinary Retention

View details

3515598
8214466
8572390
9031957
9789679
10193215
10447906
10520911
11359592
 		CTD
SIDER
571Urination Disorders15025617CTD
572Urine amphetamine positiveOFFSIDES
573Urine flow decreasedSIDER
574UrticariaCanada Vigilance: 1Canada Vigilance
SIDER
575Uterine contractions during pregnancyOFFSIDES
576Vascular purpuraSIDER
577Vascular resistance systemic decreasedOFFSIDES
578Vision Disorders9175963CTD
579Walking aid userOFFSIDES
580Wound DebridementOFFSIDES
581Wound discharge increasedSIDER
582apprehensionSIDER
583effusionOFFSIDES
584jaundice8484525CTD
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