MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Xipamide

(MTZBBNMLMNBNJL-UHFFFAOYSA-N)

Structure

SMILES: O=C(c1cc(c(cc1O)Cl)S(=O)(=O)N)Nc1c(C)cccc1C
Type(s): Experimental
ATC code(s): C03BA10
Molecular Formula:: C15H15ClN2O4S
Molecular Weight:: 354.809
Log P:: 4.4162
Hydrogen Bond Acceptor:: 6
Hydrogen Bond Donor:: 3
TPSA:: 117.87
CAS Number(s):: 14293-44-8

Synonym(s)

Xipamide

Xipamid

External Link(s)

MeSH	D014988
PubChem Compound	26618
ChEBI	135499
CHEMBL	CHEMBL517199
DrugBank	DB13803
DrugCentral	2853
IUPHAR/BPS Guide to PHARMACOLOGY	7900
KEGG	dr:D06341
Therapeutic Target Database	D0H2ZW
ZINC	538538

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Acne	FAERS: 1		US FAERS
2	Application site rash	FAERS: 1		US FAERS
3	Erythema	FAERS: 1		US FAERS
4	Pruritus	FAERS: 1		US FAERS
5	Abdominal Pain			OFFSIDES
6	Acquired diaphragmatic eventration			OFFSIDES
7	Acute prerenal failure			OFFSIDES
8	Acute respiratory failure			OFFSIDES
9	Adjustment disorder with depressed mood			OFFSIDES
10	Adnexitis			OFFSIDES
11	Alkalosis			OFFSIDES
12	Alveolitis			OFFSIDES
13	Angioedema			OFFSIDES
14	Aortic valve sclerosis			OFFSIDES
15	Arteriovenous fistula site complication			OFFSIDES
16	Arteriovenous fistula thrombosis			OFFSIDES
17	Ascites			OFFSIDES
18	Atrial tachycardia			OFFSIDES
19	Autoimmune thyroiditis			OFFSIDES
20	Azotemia		12528327	CTD
21	Blood Glucose			OFFSIDES
22	Blood cholesterol			OFFSIDES
23	Blood count abnormal			OFFSIDES
24	Blood creatine increased			OFFSIDES
25	Blood creatinine increased			OFFSIDES
26	Blood glucose decreased			OFFSIDES
27	Blood iron decreased			OFFSIDES
28	Blood potassium decreased			OFFSIDES
29	Blood sodium increased			OFFSIDES
30	Blood sodium			OFFSIDES
31	Blood triglycerides increased			OFFSIDES
32	Blood urea increased			OFFSIDES
33	Bradycardia			OFFSIDES
34	Bronchopneumonia			OFFSIDES
35	Bulbar palsy			OFFSIDES
36	Cardiac Death			OFFSIDES
37	Cardioactive drug level increased			OFFSIDES
38	Cardiovascular insufficiency			OFFSIDES
39	Catheter site infection			OFFSIDES
40	Cauda Equina Syndrome			OFFSIDES
41	Chronic left ventricular failure			OFFSIDES
42	Chronic ulcerative colitis			OFFSIDES
43	Clostridium colitis			OFFSIDES
44	Clostridium difficile colitis			OFFSIDES
45	Cold sweat			OFFSIDES
46	Colitis			OFFSIDES
47	Colon cancer recurrent			OFFSIDES
48	Creatinine urine decreased			OFFSIDES
49	Cyst			OFFSIDES
50	Dehydration			OFFSIDES
51	Demyelination			OFFSIDES
52	Dermatophytosis			OFFSIDES
53	Diabetic Nephropathy			OFFSIDES
54	Diet refusal			OFFSIDES
55	Dizziness			OFFSIDES
56	Drug level fluctuating			OFFSIDES
57	Drug toxicity			OFFSIDES
58	Dry skin			OFFSIDES
59	Electrocardiogram poor R-wave progression			OFFSIDES
60	Electrolyte depletion			OFFSIDES
61	Embolic cerebral infarction			OFFSIDES
62	Emotional distress			OFFSIDES
63	Erosive gastritis			OFFSIDES
64	Erysipelas			OFFSIDES
65	Escherichia sepsis			OFFSIDES
66	Eye inflammation			OFFSIDES
67	Gamma-Glutamyltransferase Increased			OFFSIDES
68	General physical condition			OFFSIDES
69	General physical health deterioration			OFFSIDES
70	Heparin-induced thrombocytopenia			OFFSIDES
71	Hepatitis			OFFSIDES
72	Hyperkeratosis			OFFSIDES
73	Hypertensive heart disease			OFFSIDES
74	Hypokalemia		6802373 6804002 12528327	CTD
75	Hyponatremia		12528327	CTD
76	Hypophagia			OFFSIDES
77	Idiopathic urticaria			OFFSIDES
78	Ileitis			OFFSIDES
79	Infective exacerbation of chronic obstructive airways disease			OFFSIDES
80	Intestinal infarction			OFFSIDES
81	Keratitis sicca			OFFSIDES
82	Kidney Failure			OFFSIDES
83	Left Ventricular Hypertrophy			OFFSIDES
84	Light chain disease			OFFSIDES
85	Lip erosion			OFFSIDES
86	Malignant Hypertension			OFFSIDES
87	Mitral valve sclerosis			OFFSIDES
88	Mucosal erosion			OFFSIDES
89	Mycosis Fungoides			OFFSIDES
90	Myoglobin blood increased			OFFSIDES
91	Nausea			OFFSIDES
92	Osteochondrosis			OFFSIDES
93	Parotitis			OFFSIDES
94	Polysubstance dependence			OFFSIDES
95	Proctitis			OFFSIDES
96	Proctocolitis			OFFSIDES
97	Product counterfeit			OFFSIDES
98	Prothrombin time abnormal			OFFSIDES
99	Pulmonary congestion			OFFSIDES
100	QRS axis abnormal			OFFSIDES
101	Respiratory Failure			OFFSIDES
102	Respiratory tract congestion			OFFSIDES
103	Rotavirus test positive			OFFSIDES
104	Schizophrenia			OFFSIDES
105	Scleroderma			OFFSIDES
106	Septic Shock			OFFSIDES
107	Sick Sinus Syndrome			OFFSIDES
108	Silent myocardial infarction			OFFSIDES
109	Stent occlusion			OFFSIDES
110	Stevens-Johnson Syndrome			OFFSIDES
111	Stridor			OFFSIDES
112	Subileus			OFFSIDES
113	Sudden Cardiac Death			OFFSIDES
114	Thoracotomy			OFFSIDES
115	Tracheitis			OFFSIDES
116	Transaminases increased			OFFSIDES
117	Troponin I increased			OFFSIDES
118	Unresponsive to stimuli			OFFSIDES
119	Uterine Prolapse			OFFSIDES
120	Vascular insufficiency			OFFSIDES
121	Ventricular Fibrillation			OFFSIDES
122	Visual disturbance			OFFSIDES
123	Xerosis			OFFSIDES
124	angiogram			OFFSIDES
125	muscle injury			OFFSIDES

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