MetaADEDB 2.0 @ LMMD
Deamino Arginine Vasopressin
(NFLWUMRGJYTJIN-UHFFFAOYSA-N)
Structure
SMILES
NC(=O)CC1NC(=O)C(CCC(=O)N)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)CCSSCC(NC1=O)C(=O)N1CCCC1C(=O)NC(C(=O)NCC(=O)N)CCCN=C(N)N)Cc1ccc(cc1)O
Molecular Formula:
C46H64N14O12S2
Molecular Weight:
1069.220
Log P:
1.5235
Hydrogen Bond Acceptor:
28
Hydrogen Bond Donor:
13
TPSA:
488.51
CAS Number(s):
6917-99-3; 16679-58-6; 62357-86-2
Synonym(s)
1.
Deamino Arginine Vasopressin
2.
Desmopressin
3.
Vasopressin, Deamino Arginine
4.
1-Deamino-8-D-arginine Vasopressin
5.
1-Desamino-8-arginine Vasopressin
6.
Adiuretin
7.
Adiuretin SD
8.
Apo-Desmopressin
9.
DDAVP
10.
Desmogalen
11.
Desmopressin Acetate
12.
Desmopressin Monoacetate
13.
Desmopressin Monoacetate, Trihydrate
14.
Desmopressine Ferring
15.
Desmospray
16.
Desmotabs
17.
Minirin
18.
Minurin
19.
Nocutil
20.
Octim
21.
Octostim
22.
Acetate, Desmopressin
23.
Arginine Vasopressin, Deamino
24.
Ferring, Desmopressine
25.
Monoacetate, Desmopressin
26.
Monoacetate, Trihydrate Desmopressin
27.
Trihydrate Desmopressin Monoacetate
28.
Vasopressin, 1-Deamino-8-D-arginine
29.
Vasopressin, 1-Desamino-8-arginine
External Link(s)
MeSHD003894
PubChem Compound27991
BindingDB85094
CHEMBLCHEMBL264448
IUPHAR/BPS Guide to PHARMACOLOGY2181
2182
KEGGcpd:C06944
dr:D00291
Therapeutic Target DatabaseD0Y7SJ
D0U7SH
D0N9GI
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Nasal discomfortFAERS: 76OFFSIDES
US FAERS
2Drug ineffectiveFAERS: 64
Canada Vigilance: 6		Canada Vigilance
US FAERS
3HeadacheFAERS: 32US FAERS
4SneezingFAERS: 29US FAERS
5Blood sodium decreasedFAERS: 26US FAERS
6NauseaFAERS: 22OFFSIDES
US FAERS
7DizzinessFAERS: 14
Canada Vigilance: 1		Canada Vigilance
US FAERS
8VomitingFAERS: 1416168026CTD
US FAERS
9AgitationFAERS: 11US FAERS
10SomnolenceFAERS: 11US FAERS
11TremorFAERS: 11
Canada Vigilance: 1		Canada Vigilance
US FAERS
12Instillation site painFAERS: 9US FAERS
13OverdoseFAERS: 9OFFSIDES
US FAERS
14Abdominal PainFAERS: 8US FAERS
15Cerebrovascular accidentFAERS: 8US FAERS
16FatigueFAERS: 8US FAERS
17Feeling abnormalFAERS: 8US FAERS
18LethargyFAERS: 8OFFSIDES
US FAERS
19HyperacusisFAERS: 7US FAERS
20MalaiseFAERS: 7US FAERS
21PalpitationsFAERS: 7US FAERS
22RhinalgiaFAERS: 7US FAERS
23Water IntoxicationFAERS: 7
Canada Vigilance: 1		2273207CTD
OFFSIDES
Canada Vigilance
US FAERS
24Chest PainFAERS: 6US FAERS
25Eye irritationFAERS: 6US FAERS
26PruritusFAERS: 6US FAERS
27Throat irritationFAERS: 6US FAERS
28AnxietyFAERS: 5US FAERS
29Back PainFAERS: 5US FAERS
30Burning sensationFAERS: 5OFFSIDES
US FAERS
31DehydrationFAERS: 5OFFSIDES
US FAERS
32Drug effect incompleteFAERS: 5US FAERS
33Incorrect dose administeredFAERS: 5OFFSIDES
US FAERS
34Instillation site irritationFAERS: 5US FAERS
35Product quality issueFAERS: 5US FAERS
36Product use in unapproved indicationFAERS: 5US FAERS
37SyncopeFAERS: 5US FAERS
38Unevaluable eventFAERS: 5US FAERS
39Visual disturbanceFAERS: 5OFFSIDES
US FAERS
40AnuriaFAERS: 4US FAERS
41Drug dispensing errorFAERS: 4OFFSIDES
US FAERS
42Drug effect variableFAERS: 4US FAERS
43DysuriaFAERS: 4US FAERS
44ErythemaFAERS: 4US FAERS
45Expired drug administeredFAERS: 4OFFSIDES
US FAERS
46Eye painFAERS: 4US FAERS
47Medication ErrorFAERS: 4US FAERS
48Paranasal sinus discomfortFAERS: 4US FAERS
49PolyuriaFAERS: 4

View details

72985
2123565
7256183
9839577
10233563
15169711
 		CTD
US FAERS
50Product preparation errorFAERS: 4US FAERS
51ThrombosisFAERS: 4US FAERS
52UrticariaFAERS: 4US FAERS
53VertigoFAERS: 4US FAERS
54Wrong technique in product usage processFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
55Accidental overdoseFAERS: 3US FAERS
56AmnesiaFAERS: 3OFFSIDES
US FAERS
57AstheniaFAERS: 3US FAERS
58ChillsFAERS: 3US FAERS
59CryingFAERS: 3US FAERS
60DeliriumFAERS: 3US FAERS
61DiscomfortFAERS: 3US FAERS
62DisorientationFAERS: 3US FAERS
63FlushingFAERS: 3US FAERS
64HemiparesisFAERS: 3
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
65HypersensitivityFAERS: 3US FAERS
66HypotensionFAERS: 3US FAERS
67Product preparation issueFAERS: 3US FAERS
68RhabdomyolysisFAERS: 3US FAERS
69Stevens-Johnson SyndromeFAERS: 3US FAERS
70ThirstFAERS: 3US FAERS
71Abdominal discomfortFAERS: 2US FAERS
72AngioedemaFAERS: 2US FAERS
73ApathyFAERS: 2US FAERS
74AphasiaFAERS: 2US FAERS
75AsthmaFAERS: 2US FAERS
76AtaxiaFAERS: 2US FAERS
77Blood creatinine increasedFAERS: 2US FAERS
78Blood potassium decreasedFAERS: 2US FAERS
79Deep Vein ThrombosisFAERS: 2US FAERS
80Device malfunctionFAERS: 2US FAERS
81Drug DependenceFAERS: 2US FAERS
82Drug ineffective for unapproved indicationFAERS: 2US FAERS
83DysgeusiaFAERS: 2US FAERS
84Ear discomfortFAERS: 2US FAERS
85EpistaxisFAERS: 2US FAERS
86Eye InfectionFAERS: 2OFFSIDES
US FAERS
87Gastrointestinal hypomotilityFAERS: 2US FAERS
88Gaze palsyFAERS: 2US FAERS
89HydrocephalusFAERS: 2OFFSIDES
US FAERS
90Hypertrophic CardiomyopathyFAERS: 2US FAERS
91Hyponatraemic seizureFAERS: 2US FAERS
92Inappropriate schedule of product administrationFAERS: 2US FAERS
93IncontinenceFAERS: 2US FAERS
94Mental impairmentFAERS: 2OFFSIDES
US FAERS
95NasopharyngitisFAERS: 2OFFSIDES
US FAERS
96NocturiaFAERS: 216287451CTD
US FAERS
97PainFAERS: 2US FAERS
98Post procedural complicationFAERS: 2US FAERS
99Product packaging issueFAERS: 2US FAERS
100Product storage errorFAERS: 2US FAERS
101Product use issueFAERS: 2US FAERS
102Psychiatric symptomFAERS: 2US FAERS
103Pulmonary EmbolismFAERS: 21837767CTD
US FAERS
104Rectal ProlapseFAERS: 2OFFSIDES
US FAERS
105RestlessnessFAERS: 2US FAERS
106School refusalFAERS: 2US FAERS
107ScreamingFAERS: 2OFFSIDES
US FAERS
108Sinus painFAERS: 2US FAERS
109SinusitisFAERS: 2US FAERS
110Status EpilepticusFAERS: 2US FAERS
111Urinary RetentionFAERS: 2US FAERS
112Weight decreasedFAERS: 2US FAERS
113nervous system disorderFAERS: 2US FAERS
114Activities of daily living impairedFAERS: 1US FAERS
115Acute left ventricular failureFAERS: 1US FAERS
116Acute myocardial infarctionFAERS: 1OFFSIDES
US FAERS
117AdrenalitisFAERS: 1US FAERS
118Altered state of consciousnessFAERS: 1US FAERS
119Amaurosis FugaxFAERS: 1US FAERS
120AngerFAERS: 1US FAERS
121ArthralgiaFAERS: 1US FAERS
122Atrial thrombosisFAERS: 1OFFSIDES
US FAERS
123Bladder discomfortFAERS: 1US FAERS
124Blood osmolarity decreasedFAERS: 1OFFSIDES
US FAERS
125Blood potassium increasedFAERS: 1US FAERS
126Blood sodium abnormalFAERS: 1US FAERS
127Blood sodium increasedFAERS: 1OFFSIDES
US FAERS
128Bronchial ObstructionFAERS: 1US FAERS
129Bronchial irritationFAERS: 1US FAERS
130BruxismFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
131Cardio-respiratory distressFAERS: 1US FAERS
132Cerebral InfarctionFAERS: 17752768CTD
US FAERS
133Chest discomfortFAERS: 1US FAERS
134Cold sweatFAERS: 1US FAERS
135Complex partial seizuresFAERS: 1US FAERS
136Consciousness fluctuatingFAERS: 1US FAERS
137Coronary Artery DiseaseFAERS: 1US FAERS
138CystitisFAERS: 1US FAERS
139DementiaFAERS: 1US FAERS
140Depressed Level of ConsciousnessFAERS: 1OFFSIDES
US FAERS
141Device difficult to useFAERS: 1US FAERS
142Diabetes InsipidusFAERS: 115169711CTD
OFFSIDES
US FAERS
143Diabetes MellitusFAERS: 1US FAERS
144DisabilityFAERS: 1US FAERS
145DroolingFAERS: 1US FAERS
146Drug ToleranceFAERS: 1OFFSIDES
US FAERS
147Drug administered to patient of inappropriate ageFAERS: 1US FAERS
148Drug administration errorFAERS: 1US FAERS
149Drug dose omissionFAERS: 1US FAERS
150Drug exposure during pregnancyFAERS: 1US FAERS
151Drug monitoring procedure not performedFAERS: 1US FAERS
152Drug withdrawal syndromeFAERS: 1US FAERS
153DysphoniaFAERS: 1US FAERS
154Educational problemFAERS: 1US FAERS
155Electrolyte imbalanceFAERS: 1US FAERS
156EnterobiasisFAERS: 1US FAERS
157EnuresisFAERS: 17528602
9195793
12432978		CTD
OFFSIDES
US FAERS
158EpilepsyFAERS: 1OFFSIDES
US FAERS
159Exposure via ingestionFAERS: 1US FAERS
160Eyelid margin crustingFAERS: 1US FAERS
161Foaming at mouthFAERS: 1US FAERS
162Foreign body in respiratory tractFAERS: 1US FAERS
163GlossitisFAERS: 1US FAERS
164GranulomaFAERS: 1US FAERS
165Hallucinations, mixedFAERS: 1OFFSIDES
US FAERS
166Head discomfortFAERS: 1US FAERS
167Heat ExhaustionFAERS: 1US FAERS
168HepatomegalyFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
169HypersomniaFAERS: 1US FAERS
170Hypertensive EncephalopathyFAERS: 117893586CTD
US FAERS
171HypopituitarismFAERS: 1OFFSIDES
US FAERS
172Impaired gastric emptyingFAERS: 1US FAERS
173Inappropriate schedule of drug administrationFAERS: 1US FAERS
174Incorrect product formulation administeredFAERS: 1US FAERS
175Incorrect product storageFAERS: 1US FAERS
176Incorrect route of drug administrationFAERS: 1US FAERS
177InfectionFAERS: 1US FAERS
178Infusion Site ExtravasationFAERS: 1US FAERS
179Initial insomniaFAERS: 1US FAERS
180Instillation site discomfortFAERS: 1US FAERS
181Intentional product misuseFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
182Intracranial AneurysmFAERS: 1US FAERS
183Joint swellingFAERS: 1US FAERS
184Lactation DisorderFAERS: 1US FAERS
185Live BirthFAERS: 1US FAERS
186Low birth weight babyFAERS: 1US FAERS
187LymphomaFAERS: 1US FAERS
188Malabsorption from administration siteFAERS: 1US FAERS
189Medication residue presentFAERS: 1US FAERS
190Memory impairmentFAERS: 1US FAERS
191Meniscus operationFAERS: 1US FAERS
192Muscle CrampFAERS: 1US FAERS
193Muscle RigidityFAERS: 1US FAERS
194MyalgiaFAERS: 1US FAERS
195MydriasisFAERS: 1US FAERS
196Myocardial InfarctionFAERS: 1US FAERS
197Nasal inflammationFAERS: 1US FAERS
198Nasal mucosal ulcerFAERS: 1US FAERS
199NephrolithiasisFAERS: 1US FAERS
200Neutrophil count decreasedFAERS: 1OFFSIDES
US FAERS
201Obsessive thoughtsFAERS: 1US FAERS
202Obsessive-Compulsive DisorderFAERS: 1US FAERS
203OliguriaFAERS: 1OFFSIDES
US FAERS
204Oral contusionFAERS: 1US FAERS
205Oropharyngeal painFAERS: 1US FAERS
206OsteoporosisFAERS: 1OFFSIDES
US FAERS
207PallorFAERS: 1US FAERS
208ParamnesiaFAERS: 1US FAERS
209Pericardial effusionFAERS: 1US FAERS
210PeritonitisFAERS: 1US FAERS
211Personality ChangeFAERS: 1US FAERS
212Pharmaceutical product complaintFAERS: 1OFFSIDES
US FAERS
213Pharyngolaryngeal PainFAERS: 1OFFSIDES
US FAERS
214PneumoniaFAERS: 1US FAERS
215PolydipsiaFAERS: 1US FAERS
216Poor quality sleepFAERS: 1US FAERS
217Posterior reversible encephalopathy syndromeFAERS: 1US FAERS
218Prescribed overdoseFAERS: 1OFFSIDES
US FAERS
219Procedural complicationFAERS: 1US FAERS
220Product administration errorFAERS: 1US FAERS
221Product complaintFAERS: 1US FAERS
222Product container seal issueFAERS: 1US FAERS
223Product contamination physicalFAERS: 1US FAERS
224Product dispensing errorFAERS: 1US FAERS
225Product distribution issueFAERS: 1US FAERS
226Product dose omissionFAERS: 1US FAERS
227Product intoleranceFAERS: 1US FAERS
228Product packaging quantity issueFAERS: 1US FAERS
229Product substitution issueFAERS: 1US FAERS
230Prostatic specific antigen decreasedFAERS: 1US FAERS
231Refusal of treatment by relativeFAERS: 1US FAERS
232Respiratory arrestFAERS: 1US FAERS
233Respiratory distressFAERS: 1US FAERS
234Restless Legs SyndromeFAERS: 1US FAERS
235RhinitisFAERS: 1US FAERS
236SarcoidosisFAERS: 1US FAERS
237Secretion dischargeFAERS: 1US FAERS
238SmokerFAERS: 1US FAERS
239SoporFAERS: 1US FAERS
240SplenomegalyFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
241StomatitisFAERS: 1US FAERS
242Suicide attemptFAERS: 1US FAERS
243SwellingFAERS: 1US FAERS
244Therapeutic product effect decreasedFAERS: 1US FAERS
245Therapeutic response unexpected with drug substitutionFAERS: 1US FAERS
246Thirst decreasedFAERS: 1OFFSIDES
US FAERS
247ThrombophlebitisFAERS: 1OFFSIDES
US FAERS
248Thrombosis in deviceFAERS: 1US FAERS
249TinnitusFAERS: 1US FAERS
250TonsillectomyFAERS: 1US FAERS
251Troponin increasedFAERS: 1US FAERS
252Upper-airway cough syndromeFAERS: 1US FAERS
253Urinary IncontinenceFAERS: 1US FAERS
254Urinary hesitationFAERS: 1US FAERS
255Urinary tract infectionFAERS: 1US FAERS
256Urine chloride increasedFAERS: 1US FAERS
257Urine flow decreasedFAERS: 1US FAERS
258Urine osmolarity increasedFAERS: 1US FAERS
259VIIth nerve paralysisFAERS: 1US FAERS
260Venous thrombosis limbFAERS: 1US FAERS
261AcidosisOFFSIDES
262AgraphiaOFFSIDES
263Ammonia increasedOFFSIDES
264AnhedoniaOFFSIDES
265Ankylosing spondylitisOFFSIDES
266Anti-insulin antibody positiveOFFSIDES
267Anticonvulsant drug level below therapeuticOFFSIDES
268Aortic AneurysmOFFSIDES
269AphagiaOFFSIDES
270ArteriosclerosisOFFSIDES
271Astrocytoma, low gradeOFFSIDES
272AstrocytomaOFFSIDES
273AuraOFFSIDES
274AutomatismOFFSIDES
275Benign Prostatic HyperplasiaOFFSIDES
276Blood Coagulation Disorders7960860CTD
277Blood chloride decreasedOFFSIDES
278Blood electrolytes abnormalOFFSIDES
279Blood osmolarity increasedOFFSIDES
280Blood sodiumOFFSIDES
281Bone lesionOFFSIDES
282Bowen's DiseaseOFFSIDES
283Brain ConcussionOFFSIDES
284Brain ContusionOFFSIDES
285Brain stem syndromeOFFSIDES
286Breast discomfortOFFSIDES
287Breast tendernessOFFSIDES
288Budd-Chiari SyndromeOFFSIDES
289Bulbar palsyOFFSIDES
290CalcinosisOFFSIDES
291Candida sepsisOFFSIDES
292Carnitine deficiencyOFFSIDES
293CatatoniaOFFSIDES
294Cauda Equina SyndromeOFFSIDES
295Cerebral salt-wasting syndromeOFFSIDES
296Cervical cord compressionOFFSIDES
297Cervical myelopathyOFFSIDES
298Chronic Fatigue SyndromeOFFSIDES
299Circumstance or information capable of leading to medication errorCanada Vigilance: 1Canada Vigilance
OFFSIDES
300Compression fractureOFFSIDES
301ConfabulationOFFSIDES
302Congenital choroid plexus cystOFFSIDES
303Congenital pyelocaliectasisOFFSIDES
304Cystic Fibrosis3147111CTD
305DeafnessOFFSIDES
306Differential white blood cell count abnormalOFFSIDES
307Drug withdrawal headacheOFFSIDES
308DysphasiaOFFSIDES
309Electromechanical dissociationOFFSIDES
310Endodontic procedureOFFSIDES
311Enterococcal infectionOFFSIDES
312Enterococcal sepsisOFFSIDES
313Extremity contractureOFFSIDES
314General symptomOFFSIDES
315Germ Cell CancerOFFSIDES
316GliomaOFFSIDES
317Hematoma, Subdural9579523CTD
318Hemorrhagic Disorders3259400CTD
319Heparin-induced thrombocytopeniaOFFSIDES
320HepatosplenomegalyOFFSIDES
321HiccoughOFFSIDES
322HordeolumOFFSIDES
323HypogonadismOFFSIDES
324Hyponatremia12614377
16168026
19836189		CTD
325HypophysitisOFFSIDES
326Immune reconstitution syndromeOFFSIDES
327ImpetigoOFFSIDES
328Infectious MononucleosisOFFSIDES
329Insulin-like growth factor decreasedOFFSIDES
330Insulin-like growth factor increasedOFFSIDES
331Intentional self-injuryOFFSIDES
332Intestinal ObstructionOFFSIDES
333Intestinal infarctionOFFSIDES
334Intracranial Thrombosis3259400CTD
335Left Ventricular HypertrophyOFFSIDES
336Lipodystrophy acquiredOFFSIDES
337Liver transplant rejectionOFFSIDES
338Lung infection pseudomonalOFFSIDES
339LymphedemaOFFSIDES
340Mediastinal massOFFSIDES
341MeningiomaOFFSIDES
342Meningitis herpesOFFSIDES
343Menorrhagia11943936
19236375		CTD
344Mental status changesOFFSIDES
345Metastases to adrenalsOFFSIDES
346Metastases to gallbladderOFFSIDES
347Multiple SclerosisOFFSIDES
348Muscle hypertrophyOFFSIDES
349Muscle necrosisOFFSIDES
350Myoglobin blood increasedOFFSIDES
351Nephrogenic Diabetes InsipidusOFFSIDES
352Neutropenic sepsisOFFSIDES
353Optic AtrophyOFFSIDES
354Oxygen saturation abnormalOFFSIDES
355PolymyositisOFFSIDES
356Productive CoughOFFSIDES
357Pulmonary Valve StenosisOFFSIDES
358Pulmonary arterial pressure increasedOFFSIDES
359Pustular psoriasisOFFSIDES
360PyelectasiaOFFSIDES
361Renal massOFFSIDES
362Respiratory FailureOFFSIDES
363Retinal exudatesOFFSIDES
364Right Ventricular DysfunctionOFFSIDES
365Risus sardonicusOFFSIDES
366ScotomaOFFSIDES
367Sebaceous adenomaOFFSIDES
368Seizures2273207
3147111
15623917		CTD
369Self MutilationOFFSIDES
370SequestrectomyOFFSIDES
371Shunt malfunctionOFFSIDES
372Skin IndurationOFFSIDES
373Stem cell transplantOFFSIDES
374Sudden deathOFFSIDES
375Tachycardia16168026CTD
376Therapeutic procedureOFFSIDES
377ThoracotomyOFFSIDES
378Thrombocytopenia9579523CTD
379Thyrotoxic periodic paralysisOFFSIDES
380Tonic clonic movementsOFFSIDES
381Tooth repairOFFSIDES
382Troponin I increasedOFFSIDES
383Urine ketone body presentOFFSIDES
384Urine output increasedOFFSIDES
385Vascular graft complicationOFFSIDES
386Venous Thrombosis1837767CTD
387Venous stenosisOFFSIDES
388Ventriculoperitoneal shunt malfunctionOFFSIDES
389furuncleOFFSIDES
390leiomyosarcomaOFFSIDES
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