MetaADEDB 2.0 @ LMMD
Methylene Blue
(CXKWCBBOMKCUKX-UHFFFAOYSA-M)
Structure
SMILES
CN(c1ccc2c(c1)sc1c(n2)ccc(=[N+](C)C)c1)C.[Cl-]
Type(s)
Approved; Investigational
ATC code(s)
V03AB17; V04CG05
Molecular Formula:
C16H18ClN3S
Molecular Weight:
319.852
Log P:
-0.4971
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
47.38
CAS Number(s):
61-73-4; 1341-90-8; 6476-03-5; 12262-49-6; 97130-83-1; 105504-42-5; 152071-32-4
Synonym(s)
1.
Methylene Blue
2.
Methylthionine Chloride
3.
Swiss Blue
4.
Basic Blue 9
5.
Chromosmon
6.
Methylene Blue N
7.
Methylthioninium Chloride
8.
Urolene Blue
9.
Blue 9, Basic
10.
Blue N, Methylene
11.
Blue, Methylene
12.
Blue, Swiss
13.
Blue, Urolene
External Link(s)
MeSHD008751
PubChem Compound6099
ChEBI6872
CHEMBLCHEMBL405110
DrugBankDB09241
KEGGcpd:C00220
Therapeutic Target DatabaseD0D1DR
D09NYS
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Injection site necrosisFAERS: 8US FAERS
2NecrosisFAERS: 7US FAERS
3PainFAERS: 6US FAERS
4Serotonin SyndromeFAERS: 6US FAERS
5Skin necrosisFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
6CellulitisFAERS: 4OFFSIDES
US FAERS
7Anaphylactic shockFAERS: 3US FAERS
8ErythemaFAERS: 3US FAERS
9TachycardiaFAERS: 3US FAERS
10Wrong drug administeredFAERS: 3US FAERS
11Agitation postoperativeFAERS: 2US FAERS
12AgitationFAERS: 2US FAERS
13ArachnoiditisFAERS: 2US FAERS
14Breast necrosisFAERS: 2US FAERS
15Cardiac ArrestFAERS: 2US FAERS
16ChillsFAERS: 2US FAERS
17CyanosisFAERS: 28523499
10566197		CTD
OFFSIDES
US FAERS
18Depressed Level of ConsciousnessFAERS: 2OFFSIDES
US FAERS
19Drug toxicityFAERS: 2OFFSIDES
US FAERS
20HyperpyrexiaFAERS: 2US FAERS
21HypersensitivityFAERS: 2US FAERS
22Injection Site ReactionFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
23Injection site erythemaFAERS: 2US FAERS
24Laboratory test interferenceFAERS: 2OFFSIDES
US FAERS
25Medication ErrorFAERS: 2US FAERS
26Post procedural complicationFAERS: 2OFFSIDES
US FAERS
27Product label confusionFAERS: 2US FAERS
28Product quality issueFAERS: 2US FAERS
29PruritusFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
30Skin lesionFAERS: 2OFFSIDES
US FAERS
31Thermal burnFAERS: 2US FAERS
32AcidosisFAERS: 1OFFSIDES
US FAERS
33AnxietyFAERS: 1US FAERS
34AphasiaFAERS: 116174228CTD
US FAERS
35Apparent deathFAERS: 1US FAERS
36Application site burnFAERS: 1US FAERS
37Blood potassium increasedFAERS: 1OFFSIDES
US FAERS
38Blood urea increasedFAERS: 1US FAERS
39BradyphreniaFAERS: 1US FAERS
40Brain stem syndromeFAERS: 1US FAERS
41Breast infectionFAERS: 1US FAERS
42Cardiac procedure complicationFAERS: 1US FAERS
43Catheter site infectionFAERS: 1US FAERS
44Cauda Equina SyndromeFAERS: 1US FAERS
45ChromaturiaFAERS: 1OFFSIDES
US FAERS
46ColitisFAERS: 1US FAERS
47Contrast media reactionFAERS: 1US FAERS
48DebridementFAERS: 1US FAERS
49DeliriumFAERS: 1US FAERS
50Device malfunctionFAERS: 1US FAERS
51DisorientationFAERS: 1US FAERS
52DizzinessFAERS: 1US FAERS
53Drug clearance decreasedFAERS: 1US FAERS
54DysgeusiaFAERS: 1OFFSIDES
US FAERS
55EndophthalmitisFAERS: 1US FAERS
56Flank PainFAERS: 1US FAERS
57GranulomaFAERS: 1US FAERS
58HypotensionFAERS: 11888233
14762380		CTD
US FAERS
59Iatrogenic injuryFAERS: 1US FAERS
60Imaging procedure abnormalFAERS: 1US FAERS
61Immediate post-injection reactionFAERS: 1OFFSIDES
US FAERS
62Incision site infectionFAERS: 1US FAERS
63Increased bronchial secretionFAERS: 1US FAERS
64Infected seromaFAERS: 1US FAERS
65Infusion Site ExtravasationFAERS: 1US FAERS
66Infusion site painFAERS: 1US FAERS
67Injection site painFAERS: 1US FAERS
68Low Cardiac Output SyndromeFAERS: 1OFFSIDES
US FAERS
69Lymphatic mappingFAERS: 1US FAERS
70MastitisFAERS: 1US FAERS
71Medical device complicationFAERS: 1US FAERS
72Medication residue presentFAERS: 1US FAERS
73Memory impairmentFAERS: 1US FAERS
74Mental impairmentFAERS: 1US FAERS
75Mental status changes postoperativeFAERS: 1US FAERS
76Metabolic acidosisFAERS: 1US FAERS
77Muscle RigidityFAERS: 1US FAERS
78Muscle SpasticityFAERS: 1US FAERS
79NauseaFAERS: 1US FAERS
80OnychoclasisFAERS: 1US FAERS
81OnycholysisFAERS: 1US FAERS
82OverdoseFAERS: 1US FAERS
83Poor quality drug administeredFAERS: 1US FAERS
84Post procedural painFAERS: 1US FAERS
85Post-Traumatic Stress DisorderFAERS: 1US FAERS
86Procedural complicationFAERS: 1US FAERS
87Product contaminationFAERS: 1US FAERS
88Product contamination microbialFAERS: 1US FAERS
89Product formulation issueFAERS: 1US FAERS
90Product preparation errorFAERS: 1US FAERS
91Psychiatric symptomFAERS: 1US FAERS
92Reaction to azo-dyesFAERS: 1US FAERS
93Red blood cell morphology abnormalFAERS: 1US FAERS
94Respiratory FailureFAERS: 1US FAERS
95Retinal DetachmentFAERS: 1US FAERS
96ScabFAERS: 1US FAERS
97Sexual DysfunctionFAERS: 1US FAERS
98ShockFAERS: 1US FAERS
99Sinus TachycardiaFAERS: 1US FAERS
100Skin hypertrophyFAERS: 1US FAERS
101Skin reactionFAERS: 1US FAERS
102Skin test positiveFAERS: 1US FAERS
103Soft tissue necrosisFAERS: 1US FAERS
104Systolic hypertensionFAERS: 1US FAERS
105TremorFAERS: 1US FAERS
106Urinary IncontinenceFAERS: 1US FAERS
107UrticariaFAERS: 1US FAERS
108Venous oxygen saturation decreasedFAERS: 1US FAERS
109Ventricular FibrillationFAERS: 1US FAERS
110VomitingFAERS: 1US FAERS
111Wound infection pseudomonasFAERS: 1US FAERS
112Wound necrosisFAERS: 1US FAERS
113Abdominal sepsisOFFSIDES
114Abnormal visionOFFSIDES
115Agnosia16174228CTD
116AgraphiaOFFSIDES
117AlkalosisOFFSIDES
118Allergy test positiveCanada Vigilance: 1Canada Vigilance
119AngioedemaCanada Vigilance: 1Canada Vigilance
120Anticholinergic SyndromeOFFSIDES
121ArthropathyOFFSIDES
122Ataxia16174228CTD
123AthetosisOFFSIDES
124Atrial tachycardiaOFFSIDES
125Blood creatine phosphokinase increasedOFFSIDES
126Blurred visionOFFSIDES
127Brain Diseases

View details

7549123
7700329
8803513
8879383
11799423
15923801
15948552
16364615
17953463
 		CTD
128Cardiotoxicity30590764CTD
129Cerebral disorderOFFSIDES
130Chemical and Drug Induced Liver Injury25943564CTD
131ClonusOFFSIDES
132ConfabulationOFFSIDES
133DemyelinationOFFSIDES
134Dystonia7969812CTD
135Electrocardiogram ST-T segment depressionOFFSIDES
136Emotional distressOFFSIDES
137General physical health deteriorationOFFSIDES
138Glasgow coma scaleOFFSIDES
139Hyperalgesia10422945
10481416
19794317		CTD
140HypercapniaOFFSIDES
141Hyperemia7949234CTD
142HyperreflexiaOFFSIDES
143HyperventilationOFFSIDES
144Incorrect drug administration rateOFFSIDES
145Inhibitory drug interactionOFFSIDES
146Intention tremorOFFSIDES
147LacerationOFFSIDES
148LeukoencephalopathyOFFSIDES
149MastectomyCanada Vigilance: 1Canada Vigilance
150Memory Disorders19005644
24556215		CTD
151Methemoglobinemia7075467
17122537
17612444		CTD
152NystagmusOFFSIDES
153Oculogyric crisisOFFSIDES
154PCO2 increasedOFFSIDES
155PO2 decreasedOFFSIDES
156Panic DisorderOFFSIDES
157Penile Diseases7938138CTD
158Poisoning30907955CTD
159Priapism9542685CTD
160Procedural hypotensionCanada Vigilance: 1Canada Vigilance
161Psychomotor Agitation24556215CTD
162Rash erythematousCanada Vigilance: 1Canada Vigilance
163Retinal Degeneration19384599CTD
164Sclerosing encapsulating peritonitisOFFSIDES
165StaringOFFSIDES
166Status EpilepticusOFFSIDES
167Sudden deathOFFSIDES
168Tauopathies16930453
24556215		CTD
169Vasoplegia12830064CTD
170Ventricular Dysfunction, Left30590764CTD
171Vision Disorders19384599CTD
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.