MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Terbutaline

(XWTYSIMOBUGWOL-UHFFFAOYSA-N)

Structure

SMILES: OC(c1cc(O)cc(c1)O)CNC(C)(C)C
Type(s): Approved
ATC code(s): R03AC03; R03CC03; R03CC53
Molecular Formula:: C12H19NO3
Molecular Weight:: 225.284
Log P:: 1.9102
Hydrogen Bond Acceptor:: 4
Hydrogen Bond Donor:: 4
TPSA:: 72.72
CAS Number(s):: 23031-25-6; 46719-29-3

Synonym(s)

Terbutaline

Arubendol

Asthmoprotect

Brethaire

Brethine

Bricanyl

Bricanyl SA

Butaliret

Butalitab

10.

Contimit

11.

KWD-2019

12.

Monovent

13.

Taziken

14.

Tedipulmo

15.

Terbasmin

16.

Terbul

17.

Terbutalin AL

18.

Terbutalin Stada

19.

Terbutalin-ratiopharm

20.

Terbutaline Sulfate

21.

Terbuturmant

22.

terbutalin von ct

23.

KWD 2019

24.

KWD2019

25.

Terbutalin ratiopharm

External Link(s)

MeSH	D013726
PubChem Compound	5403
BindingDB	25770
ChEBI	9449
CHEMBL	CHEMBL1760
DrugBank	DB00871
DrugCentral	2598
IUPHAR/BPS Guide to PHARMACOLOGY	560
KEGG	cpd:C07129 dr:D08570
Therapeutic Target Database	D0M8RC

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Drug exposure during pregnancy	FAERS: 15		OFFSIDES US FAERS
2	Anxiety	FAERS: 6		SIDER US FAERS
3	Tremor	FAERS: 6	View details 190674 208429 1221498 1273541 2577692 2866991 2893778 3767127 6291971 6327346 6364879 6373350 6586482 6751176 7042176 7140872 7211775 8112441 8266020 8299660 8968295	CTD SIDER US FAERS
4	Maternal exposure during pregnancy	FAERS: 5		US FAERS
5	Palpitations	FAERS: 5		SIDER US FAERS
6	Cardiac Arrest	FAERS: 4		US FAERS
7	Dizziness	FAERS: 4		SIDER US FAERS
8	Medication Error	FAERS: 4		US FAERS
9	Respiratory arrest	FAERS: 4		US FAERS
10	Electromechanical dissociation	FAERS: 3		US FAERS
11	Hypotension	FAERS: 3	3964360 7125369 7630660	CTD US FAERS
12	Tachycardia	FAERS: 3	View details 790961 1115162 1273541 2577692 2866991 4022480 10895896 12795776	CTD SIDER US FAERS
13	Aphasia	FAERS: 2		US FAERS
14	Asthma	FAERS: 2	View details 208429 628035 1221498 1273541 2578971 2828249 2933998 3582466 3609189 3707814 3964360 4479294 6327346 6364879 6586482 7140872 7148765 7211775 8112441 8968295 9759798 11729705	CTD OFFSIDES US FAERS
15	Bradycardia	FAERS: 2	7943823	CTD US FAERS
16	Complications of maternal exposure to therapeutic drugs	FAERS: 2		OFFSIDES US FAERS
17	Drug ineffective	FAERS: 2		US FAERS
18	Educational problem	FAERS: 2		US FAERS
19	Feeling abnormal	FAERS: 2		US FAERS
20	Headache	FAERS: 2		SIDER US FAERS
21	Malaise	FAERS: 2		US FAERS
22	Myocardial Infarction	FAERS: 2		US FAERS
23	Nausea	FAERS: 2	208429 6383045	CTD SIDER US FAERS
24	Nervousness	FAERS: 2		SIDER US FAERS
25	Pain	FAERS: 2	11846262	CTD US FAERS
26	Presyncope	FAERS: 2		US FAERS
27	nervous system disorder	FAERS: 2		US FAERS
28	Accidental exposure	FAERS: 1		US FAERS
29	Accidental overdose	FAERS: 1		US FAERS
30	Activities of daily living impaired	FAERS: 1		US FAERS
31	Acute myocardial infarction	FAERS: 1		US FAERS
32	Anger	FAERS: 1		US FAERS
33	Asthenia	FAERS: 1		SIDER US FAERS
34	Body height below normal	FAERS: 1		US FAERS
35	Catatonia	FAERS: 1		US FAERS
36	Chest Pain	FAERS: 1	6383045 7485336	CTD SIDER US FAERS
37	Childhood disintegrative disorder	FAERS: 1		US FAERS
38	Completed Suicide	FAERS: 1		US FAERS
39	Congenital brain damage	FAERS: 1		US FAERS
40	Diabetes Mellitus	FAERS: 1		US FAERS
41	Emotional disorder	FAERS: 1		US FAERS
42	Emotional poverty	FAERS: 1		US FAERS
43	Eye pain	FAERS: 1		US FAERS
44	Facial Pain	FAERS: 1		US FAERS
45	Feeling jittery	FAERS: 1		US FAERS
46	Fine motor delay	FAERS: 1		US FAERS
47	Flushing	FAERS: 1		SIDER US FAERS
48	Glucose tolerance increased	FAERS: 1		US FAERS
49	Hypersensitivity	FAERS: 1		US FAERS
50	Injection site erythema	FAERS: 1		US FAERS
51	Injection site pruritus	FAERS: 1		US FAERS
52	Laboratory test interference	FAERS: 1		US FAERS
53	Lip swelling	FAERS: 1		US FAERS
54	Memory impairment	FAERS: 1		US FAERS
55	Neonatal respiratory arrest	FAERS: 1		US FAERS
56	Neonatal testicular torsion	FAERS: 1		US FAERS
57	Night sweats	FAERS: 1		US FAERS
58	Obsessive-Compulsive Disorder	FAERS: 1		US FAERS
59	Pharmaceutical product complaint	FAERS: 1		US FAERS
60	Pneumonia	FAERS: 1		US FAERS
61	Pneumonitis	FAERS: 1		US FAERS
62	Pulmonary Embolism	FAERS: 1		US FAERS
63	Restlessness	FAERS: 1		US FAERS
64	Sick Sinus Syndrome	FAERS: 1		US FAERS
65	Status Epilepticus	FAERS: 1		OFFSIDES US FAERS
66	Stillbirth	FAERS: 1		US FAERS
67	Sudden death	FAERS: 1		US FAERS
68	Supraventricular tachycardia	FAERS: 1		US FAERS
69	Swelling	FAERS: 1		US FAERS
70	Thrombosis	FAERS: 1		US FAERS
71	Toothache	FAERS: 1		US FAERS
72	Urticaria	FAERS: 1	14504664	CTD US FAERS
73	Ventricular Fibrillation	FAERS: 1		US FAERS
74	Vomiting	FAERS: 1	4022480	CTD SIDER US FAERS
75	ACTH stimulation test abnormal			OFFSIDES
76	Abdominal Infection			OFFSIDES
77	Abdominal Pain			OFFSIDES
78	Abnormalities, Drug-Induced		14610225	CTD
79	Acid reflux			OFFSIDES
80	Acidosis		4052188	CTD OFFSIDES
81	Acne			OFFSIDES
82	Acute fatty liver of pregnancy			OFFSIDES
83	Acute kidney injury		2779705	CTD
84	Acute prerenal failure			OFFSIDES
85	Acute respiratory failure			OFFSIDES
86	Adenoidectomy			OFFSIDES
87	Airway Obstruction		7211775	CTD
88	Albumin globulin ratio abnormal			OFFSIDES
89	Amyloidosis		7986221	CTD
90	Anal abscess			OFFSIDES
91	Angina Pectoris		7392171	CTD
92	Angioedema			OFFSIDES
93	Anhidrosis			OFFSIDES
94	Antasthmatic drug level above therapeutic			OFFSIDES
95	Antiphospholipid Syndrome			OFFSIDES
96	Anuria			OFFSIDES
97	Aphonia			OFFSIDES
98	Apnea			OFFSIDES
99	Ascites			OFFSIDES
100	Asterixis			OFFSIDES
101	Astigmatism			OFFSIDES
102	Atelectasis			OFFSIDES
103	Atrial Fibrillation		12423819 12681894	CTD
104	Atrial tachycardia			OFFSIDES
105	Atrioventricular Block			OFFSIDES
106	Autistic Disorder		16417856 17400887	CTD
107	Bacterial disease carrier			OFFSIDES
108	Bicuspid aortic valve			OFFSIDES
109	Biliary adenoma			OFFSIDES
110	Biopsy muscle abnormal			OFFSIDES
111	Blood bicarbonate			OFFSIDES
112	Blood cortisol decreased			OFFSIDES
113	Blood creatine phosphokinase MB increased			OFFSIDES
114	Blood folate increased			OFFSIDES
115	Blood iron decreased			OFFSIDES
116	Blood magnesium increased			OFFSIDES
117	Blood pH increased			OFFSIDES
118	Blood potassium decreased			OFFSIDES
119	Blood pyruvic acid increased			OFFSIDES
120	Blood sodium			OFFSIDES
121	Blood uric acid			OFFSIDES
122	Brief psychotic disorder with marked stressors			OFFSIDES
123	Bronchial Fistula			OFFSIDES
124	Bronchial Hyperreactivity		10550748	CTD
125	Bronchial secretion retention			OFFSIDES
126	Bronchial wall thickening			OFFSIDES
127	Bronchiectasis			OFFSIDES
128	Bronchitis		4479294	CTD OFFSIDES
129	Bronchopneumonia			OFFSIDES
130	Bunion			OFFSIDES
131	Capillary Leak Syndrome		9428835 11713377	CTD
132	Cardiomyopathies		8438916	CTD
133	Cardiovascular Diseases		6702953 7055162 7468724	CTD
134	Catheter related infection			OFFSIDES
135	Cerebellar degeneration, subacute		21618259	CTD
136	Cerebral Thrombosis			OFFSIDES
137	Chemotherapeutic drug level increased			OFFSIDES
138	Chest discomfort			SIDER
139	Choking sensation			OFFSIDES
140	Cholangiolitis			OFFSIDES
141	Chronic Obstructive Airway Disease			OFFSIDES
142	Chronic left ventricular failure			OFFSIDES
143	Chylothorax			OFFSIDES
144	Circumstance or information capable of leading to medication error			OFFSIDES
145	Clostridium difficile colitis			OFFSIDES
146	Colitis			OFFSIDES
147	Colonic Pseudo-Obstruction			OFFSIDES
148	Complication of delivery			OFFSIDES
149	Confabulation			OFFSIDES
150	Congenital diaphragmatic hernia			OFFSIDES
151	Congenital heart disease			OFFSIDES
152	Congenital pulmonary hypertension			OFFSIDES
153	Congenital tricuspid valve incompetence			OFFSIDES
154	Conjunctival deposit			OFFSIDES
155	Croup infectious			OFFSIDES
156	Cryptorchidism			OFFSIDES
157	Cyanosis			OFFSIDES
158	Cytolytic hepatitis			OFFSIDES
159	Dark circles under eyes			OFFSIDES
160	Deafness			OFFSIDES
161	Dermatitis			SIDER
162	Diaphragmatic Hernia			OFFSIDES
163	Diplopia			OFFSIDES
164	Disease recurrence			OFFSIDES
165	Diverticulitis			OFFSIDES
166	Double Outlet Right Ventricle			OFFSIDES
167	Drowsiness			SIDER
168	Drug exposure via breast milk			OFFSIDES
169	Drug level below therapeutic			OFFSIDES
170	Ductus arteriosus premature closure			OFFSIDES
171	Duodenal Ulcer			OFFSIDES
172	Duodenal ulcer perforation			OFFSIDES
173	Duodenitis			OFFSIDES
174	Dysmenorrhea		788773	CTD
175	Dysmorphism			OFFSIDES
176	Dyspnea		6383045	CTD
177	Edema		8899116	CTD
178	Electrocardiogram QT interval abnormal			OFFSIDES
179	Enamel anomaly			OFFSIDES
180	Endocardial Fibroelastosis			OFFSIDES
181	Enterococcal infection			OFFSIDES
182	Epidermal necrosis			OFFSIDES
183	Erythrosis			OFFSIDES
184	Eschar			OFFSIDES
185	Eyelid Diseases			OFFSIDES
186	Failure to Thrive			OFFSIDES
187	Feeding disorder neonatal			OFFSIDES
188	Fetal Diseases		790961	CTD
189	Fetal Distress		7943823	CTD
190	Fibromyalgia			OFFSIDES
191	Fibrosis		15467267	CTD
192	Food Allergy			OFFSIDES
193	Gangrene			OFFSIDES
194	Gastrointestinal toxicity			OFFSIDES
195	General physical health deterioration			OFFSIDES
196	Genital neoplasm malignant female			OFFSIDES
197	Gestational Diabetes			OFFSIDES
198	Gingival Hyperplasia			OFFSIDES
199	Group B streptococcus neonatal sepsis			OFFSIDES
200	Heart Diseases		7915431	CTD
201	Heart failure		8438916	CTD
202	Heart sounds abnormal			OFFSIDES
203	Heparin-induced thrombocytopenia			OFFSIDES
204	Hepatic necrosis			OFFSIDES
205	Hydrothorax			OFFSIDES
206	Hypercapnia			OFFSIDES
207	Hyperdynamic left ventricle			OFFSIDES
208	Hyperglycemia		6383045	CTD
209	Hyperventilation		10895896	CTD
210	Hypokalemia		View details 1623802 1848636 2563217 2565392 2567672 2826064 3707814 4052188 6108735 7197475 9186877 11729705 12795776 15654267 17292646	CTD
211	Hypometabolism			OFFSIDES
212	Hypoplastic Left Heart Syndrome			OFFSIDES
213	Hypoxia		4052188	CTD OFFSIDES
214	Immobile			OFFSIDES
215	Incorrect route of drug administration			OFFSIDES
216	Infantile Colic			OFFSIDES
217	Injection site inflammation			OFFSIDES
218	Injection site pain			SIDER
219	Intelligence test abnormal			OFFSIDES
220	Intention tremor			OFFSIDES
221	Intestinal Perforation			OFFSIDES
222	Joint Instability			OFFSIDES
223	Joint Range of Motion Decreased			OFFSIDES
224	Kidney Failure			OFFSIDES
225	Left ventricular heave			OFFSIDES
226	Lethargy		10895896	CTD
227	Leukocytoclastic vasculitis			SIDER
228	Leukoencephalopathy			OFFSIDES
229	Lipase			OFFSIDES
230	Lipohypertrophy			OFFSIDES
231	Lung Abscess			OFFSIDES
232	Lung Diseases, Obstructive		7053695	CTD
233	Lung consolidation			OFFSIDES
234	Lung hyperinflation			OFFSIDES
235	Lupus-like syndrome			OFFSIDES
236	Lymphoma			OFFSIDES
237	Mechanical ventilation			OFFSIDES
238	Metastases to abdominal wall			OFFSIDES
239	Microcephaly			OFFSIDES
240	Motion Sickness			OFFSIDES
241	Multiple drug overdose			OFFSIDES
242	Muscle Cramp		628035	CTD
243	Muscle necrosis			OFFSIDES
244	Myelocytosis			OFFSIDES
245	Myeloid maturation arrest			OFFSIDES
246	Myocardial Ischemia		7195835	CTD
247	Myocardial rupture			OFFSIDES
248	Myoglobin blood increased			OFFSIDES
249	Neonatal aspiration			OFFSIDES
250	Neonatal respiratory failure			OFFSIDES
251	Noonan Syndrome			OFFSIDES
252	Normal delivery			OFFSIDES
253	Obstetric Labor Complications		8113646	CTD
254	Obstetric procedure complication			OFFSIDES
255	Obstruction			OFFSIDES
256	Oligohydramnios			OFFSIDES
257	Ophthalmoplegia			OFFSIDES
258	Optic Neuritis			OFFSIDES
259	Optic nerve cupping			OFFSIDES
260	Overdose			OFFSIDES
261	PCO2 increased			OFFSIDES
262	PO2 decreased			OFFSIDES
263	Paraparesis		11846262	CTD
264	Pelvic mass			OFFSIDES
265	Pemphigus			OFFSIDES
266	Pericardial effusion			OFFSIDES
267	Peritonitis			OFFSIDES
268	Phlebitis			OFFSIDES
269	Physical disability			OFFSIDES
270	Pilonidal cyst congenital			OFFSIDES
271	Pneumococcal sepsis			OFFSIDES
272	Polydactyly			OFFSIDES
273	Polyhydramnios			OFFSIDES
274	Polyuria			OFFSIDES
275	Post procedural fistula			OFFSIDES
276	Postoperative infection			OFFSIDES
277	Pre-Eclampsia			OFFSIDES
278	Presbyopia			OFFSIDES
279	Priapism		14999218	CTD OFFSIDES
280	Productive Cough			OFFSIDES
281	Propofol Infusion Syndrome			OFFSIDES
282	Prothrombin level decreased			OFFSIDES
283	Psoriasis			OFFSIDES
284	Psychomotor skills impaired			OFFSIDES
285	Pulmonary Edema		7195835 7485336 10903255	CTD
286	Pulmonary Hypertension			OFFSIDES
287	Pulmonary Infarction			OFFSIDES
288	Pulmonary Valve Stenosis			OFFSIDES
289	Pulmonary malformation			OFFSIDES
290	QRS axis abnormal			OFFSIDES
291	Quadriplegia			OFFSIDES
292	Rales			OFFSIDES
293	Reaction to medical agent preservatives			OFFSIDES
294	Renal salt-wasting syndrome			OFFSIDES
295	Renal tubular necrosis			OFFSIDES
296	Respiratory Distress Syndrome, Adult		2878809	CTD
297	Respiratory Failure			OFFSIDES
298	Respiratory Insufficiency		8016770	CTD
299	Retinopathy of Prematurity			OFFSIDES
300	Rhabdomyolysis		2779705	CTD OFFSIDES
301	Rhinitis			OFFSIDES
302	Rhinorrhea			OFFSIDES
303	Right Ventricular Hypertrophy			OFFSIDES
304	Right atrial dilatation			OFFSIDES
305	Right ventricle outflow tract obstruction			OFFSIDES
306	Sarcoidosis			OFFSIDES
307	Scedosporium infection			OFFSIDES
308	Scotoma			OFFSIDES
309	Seizures		7148765 9190242	CTD
310	Septic Shock			OFFSIDES
311	Shone complex			OFFSIDES
312	Similar reaction on previous exposure to drug			OFFSIDES
313	Sinusitis			OFFSIDES
314	Skin necrosis			OFFSIDES
315	Somnolence			SIDER
316	Sphincter of Oddi Dysfunction			OFFSIDES
317	Staring			OFFSIDES
318	Status Asthmaticus		7427548	CTD
319	Stenotrophomonas infection			OFFSIDES
320	Subileus			OFFSIDES
321	Superinfection lung			OFFSIDES
322	Sweating			SIDER
323	Swollen tear duct			OFFSIDES
324	Systolic hypertension			OFFSIDES
325	Tachycardia, Ventricular		702743	CTD
326	Tenosynovitis			OFFSIDES
327	Tension			SIDER
328	Throat irritation	Canada Vigilance: 1		Canada Vigilance
329	Transaminases increased			OFFSIDES
330	Traumatic fracture			OFFSIDES
331	Trisomy 21			OFFSIDES
332	Umbilical cord vascular disorder			OFFSIDES
333	Uterine Prolapse			OFFSIDES
334	Uterine contractions during pregnancy			OFFSIDES
335	Vasculitis, Leukocytoclastic, Cutaneous		3177969	CTD
336	Venous thrombosis limb			OFFSIDES
337	Ventricular hypoplasia			OFFSIDES
338	Visual disturbance			OFFSIDES
339	Vocal Cord Paralysis			OFFSIDES
340	Weight Gain			OFFSIDES
341	Wheelchair user			OFFSIDES
342	Williams Syndrome			OFFSIDES
343	Wolff-Parkinson-White Syndrome			OFFSIDES
344	oligodendroglioma			OFFSIDES

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