MetaADEDB 2.0 @ LMMD
Ceftazidime
(ORFOPKXBNMVMKC-DWVKKRMSSA-N)
Structure
SMILES
O=C1[C@@H](NC(=O)/C(=N\OC(C(=O)O)(C)C)/c2csc(n2)N)[C@@H]2N1C(=C(CS2)C[n+]1ccccc1)C(=O)[O-]
Type(s)
Approved
ATC code(s)
J01DD02
Molecular Formula:
C22H22N6O7S2
Molecular Weight:
546.576
Log P:
-0.3892
Hydrogen Bond Acceptor:
14
Hydrogen Bond Donor:
3
TPSA:
244.76
CAS Number(s):
72558-82-8; 78439-06-2
Synonym(s)
1.
Ceftazidime
2.
Ceftazidime Anhydrous
3.
Ceftazidime Pentahydrate
4.
Fortaz
5.
Fortum
6.
GR-20263
7.
LY-139381
8.
Pyridinium, 1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, inner salt, pentahydrate, (6R-(6alpha,7beta(Z)))-
9.
Tazidime
10.
GR 20263
11.
GR20263
12.
LY 139381
13.
LY139381
External Link(s)
MeSHD002442
PubChem Compound73415817
5481173
57514439
BindingDB50420259
ChEBI3508
CHEMBLCHEMBL44354
DrugBankDB00438
KEGGcpd:C06889
dr:D07654
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1PruritusFAERS: 13SIDER
US FAERS
2Anaphylactic shockFAERS: 9SIDER
US FAERS
3Chest discomfortFAERS: 8US FAERS
4Status EpilepticusFAERS: 78122952
11498064
CTD
US FAERS
5UrticariaFAERS: 711792017CTD
SIDER
US FAERS
6VomitingFAERS: 7SIDER
US FAERS
7HypersensitivityFAERS: 6SIDER
US FAERS
8Chest PainFAERS: 5US FAERS
9DizzinessFAERS: 53140957CTD
SIDER
US FAERS
10HypotensionFAERS: 5SIDER
US FAERS
11Rash erythematousFAERS: 5US FAERS
12ChillsFAERS: 4US FAERS
13ColitisFAERS: 4SIDER
US FAERS
14ErythemaFAERS: 4OFFSIDES
US FAERS
15MyoclonusFAERS: 4

View details

CTD
SIDER
US FAERS
16PalpitationsFAERS: 4US FAERS
17Product quality issueFAERS: 4US FAERS
18TremorFAERS: 43046579CTD
SIDER
US FAERS
19WheezingFAERS: 4US FAERS
20Blood creatinine increasedFAERS: 3US FAERS
21Blood sodium increasedFAERS: 3OFFSIDES
US FAERS
22Cardiac ArrestFAERS: 3US FAERS
23CyanosisFAERS: 3US FAERS
24DehydrationFAERS: 3US FAERS
25DisorientationFAERS: 3US FAERS
26DysarthriaFAERS: 317325906CTD
US FAERS
27PallorFAERS: 3US FAERS
28Acute kidney injuryFAERS: 217036408CTD
US FAERS
29AgitationFAERS: 2SIDER
US FAERS
30Altered state of consciousnessFAERS: 2OFFSIDES
US FAERS
31Anaphylactoid ReactionFAERS: 2US FAERS
32AngioedemaFAERS: 2SIDER
US FAERS
33AsterixisFAERS: 2SIDER
US FAERS
34Blunted affectFAERS: 2US FAERS
35Clostridium difficile colitisFAERS: 2US FAERS
36DysphoniaFAERS: 2US FAERS
37Electrolyte imbalanceFAERS: 2US FAERS
38EosinophiliaFAERS: 2SIDER
US FAERS
39Flat affectFAERS: 2US FAERS
40Foaming at mouthFAERS: 2US FAERS
41Kounis SyndromeFAERS: 2US FAERS
42Limb discomfortFAERS: 2US FAERS
43NeutropeniaFAERS: 2SIDER
US FAERS
44PetechiaeFAERS: 2US FAERS
45Pharmaceutical product complaintFAERS: 2US FAERS
46ShockFAERS: 2US FAERS
47ThrombocytopeniaFAERS: 2SIDER
US FAERS
48Urinary tract infectionFAERS: 2US FAERS
49VasculitisFAERS: 2US FAERS
50pseudomembranous colitisFAERS: 2SIDER
US FAERS
51Apparent life threatening eventFAERS: 1US FAERS
52ArthralgiaFAERS: 1US FAERS
53AstheniaFAERS: 1US FAERS
54AsthmaFAERS: 1US FAERS
55Blood pressure immeasurableFAERS: 1US FAERS
56Blood urea increasedFAERS: 1OFFSIDES
US FAERS
57Blood urine presentFAERS: 1US FAERS
58Bronchial secretion retentionFAERS: 1US FAERS
59CellulitisFAERS: 1US FAERS
60Cerebrovascular accidentFAERS: 1US FAERS
61Choking sensationFAERS: 1US FAERS
62Concomitant disease aggravatedFAERS: 1US FAERS
63ConjunctivitisFAERS: 1US FAERS
64Depressed Level of ConsciousnessFAERS: 1OFFSIDES
US FAERS
65DiscomfortFAERS: 1US FAERS
66Drug administration errorFAERS: 1US FAERS
67Drug exposure during pregnancyFAERS: 1US FAERS
68Drug toxicityFAERS: 1US FAERS
69DyscheziaFAERS: 1US FAERS
70Erythema MultiformeFAERS: 1SIDER
US FAERS
71FatigueFAERS: 1US FAERS
72Febrile NeutropeniaFAERS: 1OFFSIDES
US FAERS
73FlushingFAERS: 1SIDER
US FAERS
74General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
75HeadacheFAERS: 13140957CTD
SIDER
US FAERS
76IncoherentFAERS: 1US FAERS
77InfectionFAERS: 18853002
21227004
CTD
OFFSIDES
US FAERS
78Infectious peritonitisFAERS: 1US FAERS
79Infusion Site ExtravasationFAERS: 1US FAERS
80KetoacidosisFAERS: 1US FAERS
81LaryngospasmFAERS: 1US FAERS
82LeukopeniaFAERS: 1SIDER
US FAERS
83Long QT SyndromeFAERS: 1US FAERS
84MaculeFAERS: 1US FAERS
85MalaiseFAERS: 1US FAERS
86Mental status changesFAERS: 1US FAERS
87MyalgiaFAERS: 1US FAERS
88NauseaFAERS: 1SIDER
US FAERS
89Neutrophil count decreasedFAERS: 1OFFSIDES
US FAERS
90No reaction on previous exposure to drugFAERS: 1US FAERS
91Oral pruritusFAERS: 1US FAERS
92Pathogen resistanceFAERS: 1OFFSIDES
US FAERS
93Peripheral swellingFAERS: 1US FAERS
94PneumoniaFAERS: 13578331
21227004
CTD
US FAERS
95PneumothoraxFAERS: 1US FAERS
96PsoriasisFAERS: 1US FAERS
97PurpuraFAERS: 1US FAERS
98RalesFAERS: 1US FAERS
99Respiratory distressFAERS: 1US FAERS
100RestlessnessFAERS: 1US FAERS
101SepsisFAERS: 1US FAERS
102Septic ShockFAERS: 1OFFSIDES
US FAERS
103Serum SicknessFAERS: 1US FAERS
104SneezingFAERS: 1US FAERS
105SomnolenceFAERS: 1US FAERS
106SplenomegalyFAERS: 1US FAERS
107StomatitisFAERS: 1US FAERS
108SyncopeFAERS: 1US FAERS
109Throat irritationFAERS: 1US FAERS
110ThrombosisFAERS: 1US FAERS
111TinnitusFAERS: 1US FAERS
112Unevaluable eventFAERS: 1US FAERS
113White blood cell count decreasedFAERS: 1US FAERS
114jaundiceFAERS: 1SIDER
US FAERS
115nervous system disorderFAERS: 1SIDER
US FAERS
116treatment failureFAERS: 1US FAERS
117Abdominal PainSIDER
118Abdominal tendernessOFFSIDES
119Abnormal visionOFFSIDES
120Abnormalities, Drug-Induced29596928CTD
121Abscess14691658CTD
OFFSIDES
122Acute respiratory failureOFFSIDES
123Acute sinusitisOFFSIDES
124AgranulocytosisSIDER
125Alanine Aminotransferase IncreasedOFFSIDES
126Alcohol IntoleranceSIDER
127Allergic exanthemaSIDER
128AlopeciaOFFSIDES
129Anal FissureOFFSIDES
130Anal FistulaOFFSIDES
131Anemia, Hemolytic17381629CTD
132AnorexiaOFFSIDES
133AnosmiaOFFSIDES
134AnoxiaOFFSIDES
135Aortic RuptureOFFSIDES
136Application site painSIDER
137Articulation Disorders17325906CTD
138Artificial anusOFFSIDES
139AscitesOFFSIDES
140Aspiration PneumoniaOFFSIDES
141AtelectasisOFFSIDES
142Atrial tachycardiaOFFSIDES
143Bacillus infectionOFFSIDES
144Bacteremia16918060CTD
145Beta 2 microglobulin increasedOFFSIDES
146Biliary Tract Diseases20071298CTD
147Bilirubin conjugated increasedOFFSIDES
148BlepharoptosisOFFSIDES
149Blood GlucoseOFFSIDES
150Blood albumin decreasedOFFSIDES
151Blood alkaline phosphatase increasedOFFSIDES
152Blood and lymphatic system disordersSIDER
153Blood beta-D-glucan increasedOFFSIDES
154Blood creatine increasedOFFSIDES
155Blood creatine phosphokinase decreasedOFFSIDES
156Blood creatinine decreasedOFFSIDES
157Blood lactate dehydrogenase increasedOFFSIDES
158Blood parathyroid hormone increasedOFFSIDES
159Blood potassium increasedOFFSIDES
160Blood pressure fluctuationOFFSIDES
161Blood sodiumOFFSIDES
162Bone lesionOFFSIDES
163Bone marrow depressionOFFSIDES
164Bone painOFFSIDES
165BradycardiaOFFSIDES
166Brain Diseases10070247
17325906
CTD
167BronchitisOFFSIDES
168Bronchopneumonia9576415CTD
OFFSIDES
169BronchospasmSIDER
170Candidiasis12623318CTD
171Cardiac TamponadeOFFSIDES
172Catheter related infectionOFFSIDES
173Chemotherapeutic drug level increasedOFFSIDES
174CholangiolitisOFFSIDES
175CholestasisSIDER
176Confusion

View details

CTD
177Coombs test positiveSIDER
178Delayed engraftmentOFFSIDES
179Dementia14671069CTD
180DemyelinationOFFSIDES
181DermatitisSIDER
182Device related infectionOFFSIDES
183DiarrheaOFFSIDES
184Diastolic dysfunctionOFFSIDES
185Disease ProgressionOFFSIDES
186Disseminated Intravascular CoagulationOFFSIDES
187Disulfiram like reactionSIDER
188Drug Eruptions11792017CTD
189Drug withdrawal headacheOFFSIDES
190Duodenal UlcerOFFSIDES
191DysgeusiaSIDER
192Embryo Loss29596928CTD
193EmpyemaOFFSIDES
194EndocarditisOFFSIDES
195Enterococcal infectionOFFSIDES
196EpiglottitisOFFSIDES
197Escherichia coli Infections14691658CTD
198Escherichia infectionOFFSIDES
199ExcitabilitySIDER
200Facial NeuralgiaOFFSIDES
201Fatty LiverOFFSIDES
202Fecal Incontinence17325906CTD
203Fever17325906CTD
204Fungal peritonitisOFFSIDES
205Gamma-Glutamyltransferase IncreasedOFFSIDES
206Gastrointestinal PainSIDER
207Gaze palsyOFFSIDES
208Gingival HypertrophyOFFSIDES
209Gram-Negative Bacterial Infections1923920CTD
210Hallucinations1583528
3140957
CTD
211Heart-lung transplant rejectionOFFSIDES
212HemiplegiaOFFSIDES
213Heparin-induced thrombocytopeniaOFFSIDES
214HepatotoxicityOFFSIDES
215Herpes Zoster OticusOFFSIDES
216Histiocytosis haematophagicOFFSIDES
217Hyperosmolar stateOFFSIDES
218HypoxiaOFFSIDES
219InfestationSIDER
220InflammationSIDER
221Injection site painSIDER
222Instillation site painSIDER
223Intestinal adenocarcinomaOFFSIDES
224Kidney FailureOFFSIDES
225LethargySIDER
226Leukopenia neonatalOFFSIDES
227Liver diseases21227004CTD
228Local reactionSIDER
229Lymphocyte count decreasedOFFSIDES
230LymphocytosisSIDER
231Markedly reduced dietary intakeOFFSIDES
232Mastication disorderOFFSIDES
233MastoiditisOFFSIDES
234Mechanical ventilationOFFSIDES
235Mediastinal shiftOFFSIDES
236Meningitis, Bacterial8122952CTD
237Meningitis, Haemophilus6322679CTD
238Meningitis3578331CTD
239Metabolic acidosisOFFSIDES
240MetaplasiaOFFSIDES
241Micturition frequency decreasedOFFSIDES
242Mouth BreathingOFFSIDES
243Musculoskeletal chest painOFFSIDES
244Mycobacterium abscessus InfectionOFFSIDES
245Nephritis, Interstitial9033764CTD
246Neutropenic colitisOFFSIDES
247NystagmusOFFSIDES
248OliguriaOFFSIDES
249Oral candidiasisSIDER
250Osteomyelitis1601755
3046579
CTD
251PainOFFSIDES
SIDER
252PancytopeniaSIDER
253Perianal abscessOFFSIDES
254Peritoneal DialysisOFFSIDES
255Peritonitis7827199CTD
256PhlebitisSIDER
257PlasmacytomaOFFSIDES
258Pneumonia, Bacterial1583528
17325906
CTD
259Post procedural bile leakOFFSIDES
260Post procedural complicationOFFSIDES
261Propionibacterium infectionOFFSIDES
262Protein total decreasedOFFSIDES
263Pseudomonas Infections

View details

CTD
264Psychiatric symptomOFFSIDES
265Pulmonary HypertensionOFFSIDES
266Pulmonary interstitial emphysema syndromeOFFSIDES
267PyelonephritisOFFSIDES
268Reaction gastrointestinalSIDER
269Respiratory FailureOFFSIDES
270Respiratory tract infection fungalOFFSIDES
271Reticulocyte count increasedOFFSIDES
272Retinal infarctionOFFSIDES
273Retinopathy of PrematurityOFFSIDES
274RhabdomyolysisOFFSIDES
275Right Ventricular HypertrophyOFFSIDES
276Seizures3140957
7855759
19421963
CTD
277Soft Tissue InfectionOFFSIDES
278Soft tissue inflammationOFFSIDES
279Sputum culture positiveOFFSIDES
280Staphylococcal Infections8150772
8460924
CTD
281Stem cell transplantOFFSIDES
282Stevens-Johnson Syndrome25811541CTD
OFFSIDES
SIDER
283Streptococcal Infections9755831
16918060
CTD
284StrongyloidiasisOFFSIDES
285Synovial CystOFFSIDES
286Therapy non-responderOFFSIDES
287ThrombocytosisSIDER
288ThrombophlebitisSIDER
289ThymectomyOFFSIDES
290Tooth ExtractionOFFSIDES
291Toxic Epidermal NecrolysisSIDER
292ToxoplasmosisOFFSIDES
293Transaminases increasedOFFSIDES
294Upper respiratory tract inflammationOFFSIDES
295Urinary tract infection enterococcalOFFSIDES
296Venoocclusive diseaseOFFSIDES
297Visual disturbanceOFFSIDES
298Wound ComplicationOFFSIDES
299Wound eviscerationOFFSIDES
300bad tasteSIDER
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