MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

voglibose

(FZNCGRZWXLXZSZ-CIQUZCHMSA-N)

Structure

SMILES: OCC(N[C@H]1C[C@](O)(CO)[C@H]([C@@H]([C@H]1O)O)O)CO
Type(s): Investigational
ATC code(s): A10BF03
Molecular Formula:: C10H21NO7
Molecular Weight:: 267.276
Log P:: -4.1015
Hydrogen Bond Acceptor:: 8
Hydrogen Bond Donor:: 8
TPSA:: 153.64
CAS Number(s):: 83480-29-9

Synonym(s)

voglibose

3,4-dideoxy-4-((2-hydroxy-1-(hydroxymethyl)ethyl)amino)-2-C-(hydroxymethyl)-D-epi-inositol

Basen

N-(1,3-dihydroxy-2-propyl)valiolamine

External Link(s)

MeSH	C102817
PubChem Compound	444020
BindingDB	50263044
ChEBI	32300
CHEMBL	CHEMBL476960
DrugBank	DB04878
DrugCentral	2845
KEGG	dr:D01665
Therapeutic Target Database	D04ZTY
ZINC	3788703

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abscess management		OFFSIDES
2	Abuse		OFFSIDES
3	Acarodermatitis		OFFSIDES
4	Activation syndrome		OFFSIDES
5	Activities of daily living impaired		OFFSIDES
6	Alanine Aminotransferase Increased		OFFSIDES
7	Altered state of consciousness		OFFSIDES
8	Alveolitis		OFFSIDES
9	Anger		OFFSIDES
10	Angiodysplasia		OFFSIDES
11	Angioedema		OFFSIDES
12	Anorexia		OFFSIDES
13	Anti-GAD antibody positive		OFFSIDES
14	Anti-insulin antibody positive		OFFSIDES
15	Anticholinergic Syndrome		OFFSIDES
16	Aortic Aneurysm		OFFSIDES
17	Apathy		OFFSIDES
18	Arteriosclerosis Obliterans		OFFSIDES
19	Arteriosclerotic gangrene		OFFSIDES
20	Arteriovenous fistula		OFFSIDES
21	Arteriovenous graft site infection		OFFSIDES
22	Ascites		OFFSIDES
23	Aspartate aminotransferase decreased		OFFSIDES
24	Atrioventricular Block		OFFSIDES
25	Autoimmune thrombocytopenia		OFFSIDES
26	Axonal neuropathy		OFFSIDES
27	Band neutrophil percentage increased		OFFSIDES
28	Blood Glucose		OFFSIDES
29	Blood albumin decreased		OFFSIDES
30	Blood alkaline phosphatase increased		OFFSIDES
31	Blood chloride increased		OFFSIDES
32	Blood cholinesterase decreased		OFFSIDES
33	Blood creatine phosphokinase increased		OFFSIDES
34	Blood creatinine increased		OFFSIDES
35	Blood glucose decreased		OFFSIDES
36	Blood glucose fluctuation		OFFSIDES
37	Blood lactate dehydrogenase increased		OFFSIDES
38	Blood magnesium decreased		OFFSIDES
39	Blood potassium increased		OFFSIDES
40	Blood sodium		OFFSIDES
41	Blood triglycerides increased		OFFSIDES
42	Blood urea increased		OFFSIDES
43	Blood uric acid		OFFSIDES
44	Blood urine present		OFFSIDES
45	Body Temperature		OFFSIDES
46	Bradycardia		OFFSIDES
47	Cardiotoxicity		OFFSIDES
48	Cataplexy		OFFSIDES
49	Central nervous system lesion		OFFSIDES
50	Cerebellar infarction		OFFSIDES
51	Chemical and Drug Induced Liver Injury	11446671	CTD
52	Chemotherapeutic drug level increased		OFFSIDES
53	Cholangiolitis		OFFSIDES
54	Cholestasis	11446671	CTD
55	Chromaturia		OFFSIDES
56	Cold sweat		OFFSIDES
57	Colitis		OFFSIDES
58	Coronary angioplasty		OFFSIDES
59	Dehydration		OFFSIDES
60	Depressed Level of Consciousness		OFFSIDES
61	Diabetes		OFFSIDES
62	Diabetes Insipidus		OFFSIDES
63	Diabetes Mellitus	11446671	CTD
64	Diabetes mellitus inadequate control		OFFSIDES
65	Diabetic Nephropathy		OFFSIDES
66	Disease Progression		OFFSIDES
67	Disseminated Intravascular Coagulation		OFFSIDES
68	Dizziness	9804082	CTD
69	Drowsiness		OFFSIDES
70	Duodenal Ulcer		OFFSIDES
71	Dysuria		OFFSIDES
72	Enterococcal sepsis		OFFSIDES
73	Enterocolitis		OFFSIDES
74	Eosinophilic Pneumonia		OFFSIDES
75	Eosinophilic myocarditis		OFFSIDES
76	Epistaxis		OFFSIDES
77	Erection increased		OFFSIDES
78	Erythema Multiforme		OFFSIDES
79	Erythema		OFFSIDES
80	Facial wasting		OFFSIDES
81	False positive laboratory result		OFFSIDES
82	Febrile Neutropenia		OFFSIDES
83	Floppy iris syndrome		OFFSIDES
84	Gamma-Glutamyltransferase Increased		OFFSIDES
85	Gastric ulcer		OFFSIDES
86	Gastrointestinal mucosal disorder		OFFSIDES
87	Genital discharge		OFFSIDES
88	Genital erosion		OFFSIDES
89	Gingival Hypertrophy		OFFSIDES
90	Gingival erythema		OFFSIDES
91	Glucagonoma		OFFSIDES
92	Heat illness		OFFSIDES
93	Hemiplegia		OFFSIDES
94	Hepatitis B DNA increased		OFFSIDES
95	Hepatitis B		OFFSIDES
96	Hiccough		OFFSIDES
97	Hypercapnia		OFFSIDES
98	Hypervigilance		OFFSIDES
99	Hypogeusia		OFFSIDES
100	Hypotension	16682681	CTD
101	Impaired insulin secretion		OFFSIDES
102	Incoherent		OFFSIDES
103	Intubation		OFFSIDES
104	Lip erosion		OFFSIDES
105	Loss of proprioception		OFFSIDES
106	Lung infection pseudomonal		OFFSIDES
107	Lymph Node Tuberculosis		OFFSIDES
108	Lymphocyte count decreased		OFFSIDES
109	Lymphocyte percentage decreased		OFFSIDES
110	Lymphocyte stimulation test positive		OFFSIDES
111	Malignant neoplasm of spinal cord		OFFSIDES
112	Multiple drug overdose		OFFSIDES
113	Muscle Weakness		OFFSIDES
114	Muscle enzyme		OFFSIDES
115	Myofascitis		OFFSIDES
116	Myoglobin blood increased		OFFSIDES
117	Nasopharyngitis		OFFSIDES
118	Nausea	9804082	CTD
119	Necrosis	11446671	CTD
120	Nephrectomy		OFFSIDES
121	Nephrotic Syndrome		OFFSIDES
122	Neuroleptic Malignant Syndrome		OFFSIDES
123	Neutropenic infection		OFFSIDES
124	Neutrophil count decreased		OFFSIDES
125	Oculomucocutaneous syndrome		OFFSIDES
126	Oliguria		OFFSIDES
127	Oropharyngitis fungal		OFFSIDES
128	Osteosclerosis		OFFSIDES
129	PROTHROMBIN TIME		OFFSIDES
130	Pain of skin		OFFSIDES
131	Pemphigus		OFFSIDES
132	Peripheral embolism		OFFSIDES
133	Peritonsillitis		OFFSIDES
134	Platelet count abnormal		OFFSIDES
135	Pneumatosis Cystoides Intestinalis		OFFSIDES
136	Pneumocystis jiroveci pneumonia		OFFSIDES
137	Pneumoperitoneum		OFFSIDES
138	Polymyalgia Rheumatica		OFFSIDES
139	Priapism		OFFSIDES
140	Protein total decreased		OFFSIDES
141	Pseudomonal sepsis		OFFSIDES
142	Psychiatric symptom		OFFSIDES
143	Pulmonary arterial hypertension		OFFSIDES
144	Pupillary light reflex tests abnormal		OFFSIDES
145	Radial nerve palsy		OFFSIDES
146	Renal tubular disorder		OFFSIDES
147	Rhabdomyolysis		OFFSIDES
148	Scrotal erythema		OFFSIDES
149	Senile dementia		OFFSIDES
150	Serratia sepsis		OFFSIDES
151	Shunt malfunction		OFFSIDES
152	Sick Sinus Syndrome		OFFSIDES
153	Skin Erosion		OFFSIDES
154	Skin discomfort		OFFSIDES
155	Splenic neoplasm malignancy unspecified		OFFSIDES
156	Stitch abscess		OFFSIDES
157	Sudden death		OFFSIDES
158	Surfactant protein increased		OFFSIDES
159	Thoracic cavity drainage		OFFSIDES
160	Thrombin-antithrombin III complex increased		OFFSIDES
161	Thrombotic cerebral infarction		OFFSIDES
162	Tinea Pedis		OFFSIDES
163	Traumatic fracture		OFFSIDES
164	Unresponsive to stimuli		OFFSIDES
165	Ventricular Flutter		OFFSIDES
166	Vomiting	9804082	CTD

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