MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Nitroglycerin

(SNIOPGDIGTZGOP-UHFFFAOYSA-N)

Structure

SMILES: [O-][N+](=O)OC(CO[N+](=O)[O-])CO[N+](=O)[O-]
Type(s): Approved; Investigational
ATC code(s): C01DA02; C01DA52; C05AE01
Molecular Formula:: C3H5N3O9
Molecular Weight:: 227.087
Log P:: 0.5495
Hydrogen Bond Acceptor:: 0
Hydrogen Bond Donor:: 0
TPSA:: 165.15
CAS Number(s):: 55-63-0; 27906-99-6

Synonym(s)

Nitroglycerin

Glyceryl Trinitrate

Anginine

Dynamite

Gilustenon

Nitrangin

Nitro-Bid

Nitro-Dur

Nitrocard

10.

Nitroderm

11.

Nitroderm TTS

12.

Nitroglyn

13.

Nitrol

14.

Nitrolan

15.

Nitrong

16.

Nitrospan

17.

Nitrostat

18.

Perlinganit

19.

Susadrin

20.

Sustac

21.

Sustak

22.

Sustonit

23.

Transderm Nitro

24.

Tridil

25.

Trinitrin

26.

Trinitrolong

27.

Nitro Bid

28.

Nitro Dur

29.

NitroBid

30.

NitroDur

31.

Trinitrate, Glyceryl

External Link(s)

MeSH	D005996
PubChem Compound	4510
ChEBI	28787
CHEMBL	CHEMBL730
DrugBank	DB00727
DrugCentral	1952
IUPHAR/BPS Guide to PHARMACOLOGY	7053
KEGG	cpd:C07455 dr:D00515
Therapeutic Target Database	D07YDE D00ZHQ D0YW4P
ZINC	8214625

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Drug ineffective	FAERS: 306 Canada Vigilance: 26		Canada Vigilance US FAERS
2	Headache	FAERS: 94 Canada Vigilance: 26	View details 103418 1505148 1737261 1903583 1910019 1917174 2492322 2515215 2865615 2898636 3085698 3110103 3134314 3917307 3918653 3928252 6416043 6442006 7553811 7736873 8241457 8320100 8634492 8634922 8866624 8902249 9221864 9648986 9987697 10395629 10458141 10696890 10700763 10971600 11037739 11052511 11284996 11395995 11554966 11787934 11915580 11952579 12420670 12475575 14586357 14728706 15566422 15747070 15832742 16103548 16106903 17059437 17371354 17846781 17955171 18401549 19121572 19438913 19673898 19740120 20143247	CTD SIDER Canada Vigilance US FAERS
3	Hypotension	FAERS: 86 Canada Vigilance: 19	View details 99309 417150 804357 809711 822962 823809 1288905 1310543 1448188 1455853 1560571 1653293 1836097 1899682 2122504 2124178 2346952 2502902 2951327 2961279 3080924 3084168 3084720 3107920 3152422 3304958 3921865 3922207 3925192 3928728 3929508 3934730 5001608 6173517 6193361 6401939 6402838 6406719 6407806 6409446 6409447 6411105 6426492 6432869 6442367 6470973 6766371 6773726 6775054 6775550 6778063 6782729 6786303 6787217 6791824 6800317 6806995 6814818 6816056 6820085 6928405 7543620 7625621 8155447 8206594 8225663 8273955 8350464 9506701 9987052 10426492 10455295 10492869 10526806 10565607 10624637 11052440 11138733 11444498 11772822 11782677 12578047 14515047 14984866 15076216 15278582 15278816 15377319 17351238 17443133 18848109 19576883 19795771 19923525	CTD SIDER Canada Vigilance US FAERS
4	Product quality issue	FAERS: 68		US FAERS
5	Product solubility abnormal	FAERS: 54		US FAERS
6	Chest Pain	FAERS: 46 Canada Vigilance: 8	View details 99020 647321 2916435 3578343 5774135 8007032 9517707 10719974 10958127 12563578 14678917 15452381 15578319 15940087 16103548 16326260 16440063 17351238 19382279	CTD OFFSIDES Canada Vigilance US FAERS
7	Syncope	FAERS: 36 Canada Vigilance: 7	View details 3107920 7955594 10496436 11469429 12049376 21143500	CTD SIDER Canada Vigilance US FAERS
8	Dizziness	FAERS: 34 Canada Vigilance: 14	3085698	CTD SIDER Canada Vigilance US FAERS
9	Pharmaceutical product complaint	FAERS: 34		US FAERS
10	Myocardial Infarction	FAERS: 32 Canada Vigilance: 4	View details 819021 1836097 3304958 6160553 6409446 6409447 6428741 6432869 6805287 9610531 10475830 14729435 15204172	CTD Canada Vigilance US FAERS
11	Medication Error	FAERS: 26 Canada Vigilance: 3		Canada Vigilance US FAERS
12	Bradycardia	FAERS: 25 Canada Vigilance: 3	View details 822962 2122504 2124178 3080924 3928252 6426492 6766371 6778063 6791824 6800317 8273955 8489673 9987052	CTD OFFSIDES SIDER Canada Vigilance US FAERS
13	Cardiac Arrest	FAERS: 25 Canada Vigilance: 1		Canada Vigilance US FAERS
14	Burning sensation	FAERS: 24 Canada Vigilance: 3		Canada Vigilance SIDER US FAERS
15	Nausea	FAERS: 24 Canada Vigilance: 10		Canada Vigilance SIDER US FAERS
16	Malaise	FAERS: 20 Canada Vigilance: 3		Canada Vigilance US FAERS
17	Angina Pectoris	FAERS: 18 Canada Vigilance: 9	View details 102330 409604 686426 1810682 1917174 2471880 2508936 2515215 2571590 3110103 3114351 3147892 3918653 3985522 4213224 6416043 6421013 6775290 6811006 7530402 8138338 8319327 8634922 9408613 10678861 11132996 11168608 12565182 12771913 14968347 17075217 17177034 17645760 17689623 18388107 18795667	CTD SIDER Canada Vigilance US FAERS
18	Incorrect dose administered	FAERS: 18		US FAERS
19	Product taste abnormal	FAERS: 16 Canada Vigilance: 1		Canada Vigilance US FAERS
20	Vomiting	FAERS: 16 Canada Vigilance: 5	1903583 3928252 18800963	CTD SIDER Canada Vigilance US FAERS
21	Presyncope	FAERS: 15		US FAERS
22	Application site erythema	FAERS: 14 Canada Vigilance: 8		Canada Vigilance SIDER US FAERS
23	Application site rash	FAERS: 14 Canada Vigilance: 14		Canada Vigilance US FAERS
24	No adverse event	FAERS: 14		US FAERS
25	Product adhesion issue	FAERS: 13 Canada Vigilance: 6		Canada Vigilance US FAERS
26	Product substitution issue	FAERS: 12 Canada Vigilance: 37		Canada Vigilance US FAERS
27	Product use in unapproved indication	FAERS: 12		US FAERS
28	Product use issue	FAERS: 12		US FAERS
29	Hypersensitivity	FAERS: 11 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
30	Pain	FAERS: 11 Canada Vigilance: 1	7736873 9221864 9839827	CTD OFFSIDES Canada Vigilance US FAERS
31	Tachycardia	FAERS: 11	View details 815887 817856 6436028 6786303 6797441 9527094	CTD SIDER US FAERS
32	Application site pruritus	FAERS: 10 Canada Vigilance: 6		Canada Vigilance SIDER US FAERS
33	Drug administration error	FAERS: 10		US FAERS
34	Drug ineffective for unapproved indication	FAERS: 10 Canada Vigilance: 2		Canada Vigilance US FAERS
35	Fatigue	FAERS: 10 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
36	Product physical issue	FAERS: 9		US FAERS
37	Accidental overdose	FAERS: 8		US FAERS
38	Application site irritation	FAERS: 8 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
39	Application site pain	FAERS: 8 Canada Vigilance: 6		Canada Vigilance US FAERS
40	Contraindicated product administered	FAERS: 8		US FAERS
41	Erythema	FAERS: 8 Canada Vigilance: 18		Canada Vigilance SIDER US FAERS
42	Feeling abnormal	FAERS: 8		SIDER US FAERS
43	Skin irritation	FAERS: 8 Canada Vigilance: 4		Canada Vigilance US FAERS
44	Asthenia	FAERS: 7 Canada Vigilance: 2		Canada Vigilance OFFSIDES SIDER US FAERS
45	Expired product administered	FAERS: 7 Canada Vigilance: 1		Canada Vigilance US FAERS
46	Incorrect drug administration duration	FAERS: 7		US FAERS
47	Palpitations	FAERS: 7 Canada Vigilance: 2		Canada Vigilance SIDER US FAERS
48	Poor quality drug administered	FAERS: 7		US FAERS
49	Pruritus	FAERS: 7 Canada Vigilance: 23		Canada Vigilance SIDER US FAERS
50	Ventricular Fibrillation	FAERS: 7	3160229	CTD US FAERS
51	Acute myocardial infarction	FAERS: 6		OFFSIDES US FAERS
52	Application site reaction	FAERS: 6 Canada Vigilance: 35		Canada Vigilance SIDER US FAERS
53	Circumstance or information capable of leading to medication error	FAERS: 6		US FAERS
54	Cold sweat	FAERS: 6 Canada Vigilance: 1		Canada Vigilance US FAERS
55	Drug effect incomplete	FAERS: 6		US FAERS
56	Overdose	FAERS: 6		OFFSIDES US FAERS
57	Therapeutic response unexpected	FAERS: 6		US FAERS
58	Accidental exposure to product	FAERS: 5		US FAERS
59	Cerebrovascular accident	FAERS: 5 Canada Vigilance: 1		Canada Vigilance US FAERS
60	Drug dose omission	FAERS: 5		US FAERS
61	Drug effect delayed	FAERS: 5		US FAERS
62	Incorrect product storage	FAERS: 5		US FAERS
63	Therapy non-responder	FAERS: 5		US FAERS
64	Violence-related symptom	FAERS: 5		US FAERS
65	Wrong technique in product usage process	FAERS: 5		US FAERS
66	Adverse event	FAERS: 4		US FAERS
67	Altered state of consciousness	FAERS: 4		US FAERS
68	Application site burn	FAERS: 4 Canada Vigilance: 1		Canada Vigilance US FAERS
69	Ataxia	FAERS: 4	18800963	CTD US FAERS
70	Dehydration	FAERS: 4		OFFSIDES US FAERS
71	Device Failure	FAERS: 4 Canada Vigilance: 1		Canada Vigilance US FAERS
72	Device malfunction	FAERS: 4 Canada Vigilance: 1		Canada Vigilance US FAERS
73	Discomfort	FAERS: 4		US FAERS
74	Disorientation	FAERS: 4		US FAERS
75	Drug dispensing error	FAERS: 4		US FAERS
76	Hypoxia	FAERS: 4	6785177 9412885	CTD OFFSIDES SIDER US FAERS
77	Lethargy	FAERS: 4	1903583	CTD US FAERS
78	Memory impairment	FAERS: 4 Canada Vigilance: 2		Canada Vigilance US FAERS
79	Nasopharyngitis	FAERS: 4		OFFSIDES US FAERS
80	Product storage error	FAERS: 4		US FAERS
81	Somnolence	FAERS: 4		SIDER US FAERS
82	Swelling	FAERS: 4		US FAERS
83	Thrombocytopenia	FAERS: 4		US FAERS
84	Unresponsive to stimuli	FAERS: 4		US FAERS
85	Angioplasty	FAERS: 3		US FAERS
86	Atrial Fibrillation	FAERS: 3		US FAERS
87	Atrioventricular Block	FAERS: 3	8225663	CTD SIDER US FAERS
88	Chest discomfort	FAERS: 3		SIDER US FAERS
89	Coronary Artery Disease	FAERS: 3	3141188	CTD US FAERS
90	Dysgeusia	FAERS: 3		US FAERS
91	Dysphonia	FAERS: 3		OFFSIDES US FAERS
92	Epistaxis	FAERS: 3		US FAERS
93	Flushing	FAERS: 3 Canada Vigilance: 2	1910019 3134314 9648986	CTD SIDER Canada Vigilance US FAERS
94	Hypertensive emergency	FAERS: 3		US FAERS
95	Intentional product misuse	FAERS: 3		US FAERS
96	Lip swelling	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
97	Mental status changes	FAERS: 3		US FAERS
98	Product label confusion	FAERS: 3		US FAERS
99	Product packaging issue	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
100	Sinus bradycardia	FAERS: 3		OFFSIDES US FAERS
101	Tongue discomfort	FAERS: 3		US FAERS
102	Vertigo	FAERS: 3 Canada Vigilance: 1	11395995	CTD SIDER Canada Vigilance US FAERS
103	Wrong technique in drug usage process	FAERS: 3		US FAERS
104	Ageusia	FAERS: 2	2492914	CTD US FAERS
105	Amnesia	FAERS: 2		US FAERS
106	Anger	FAERS: 2		OFFSIDES US FAERS
107	Anorectal discomfort	FAERS: 2		US FAERS
108	Application site dryness	FAERS: 2		US FAERS
109	Application site scab	FAERS: 2		US FAERS
110	Application site vesicles	FAERS: 2 Canada Vigilance: 2		Canada Vigilance US FAERS
111	Back Pain	FAERS: 2		US FAERS
112	Back disorder	FAERS: 2		US FAERS
113	Blindness	FAERS: 2		US FAERS
114	Blood glucose increased	FAERS: 2		US FAERS
115	Cellulitis	FAERS: 2		OFFSIDES US FAERS
116	Cerebral Infarction	FAERS: 2		US FAERS
117	Coma scale abnormal	FAERS: 2		US FAERS
118	Delirium	FAERS: 2		US FAERS
119	Disease recurrence	FAERS: 2 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
120	Expired drug administered	FAERS: 2		US FAERS
121	Extra dose administered	FAERS: 2		US FAERS
122	Inappropriate schedule of product administration	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
123	Incorrect product administration duration	FAERS: 2		US FAERS
124	Incorrect storage of drug	FAERS: 2		US FAERS
125	Intentional drug misuse	FAERS: 2		US FAERS
126	Intentional product use issue	FAERS: 2		US FAERS
127	Intercepted medication error	FAERS: 2		US FAERS
128	Intercepted product dispensing error	FAERS: 2		US FAERS
129	Local reaction	FAERS: 2		US FAERS
130	Mediastinitis	FAERS: 2		US FAERS
131	Necrosis	FAERS: 2		US FAERS
132	Occupational exposure to product	FAERS: 2		US FAERS
133	Pancytopenia	FAERS: 2		US FAERS
134	Pneumonia	FAERS: 2		US FAERS
135	Posterior reversible encephalopathy syndrome	FAERS: 2		US FAERS
136	Product container issue	FAERS: 2		US FAERS
137	Product label issue	FAERS: 2		US FAERS
138	Sepsis	FAERS: 2		US FAERS
139	Sexual Dysfunction	FAERS: 2		US FAERS
140	Shock	FAERS: 2		SIDER US FAERS
141	Stress	FAERS: 2		OFFSIDES US FAERS
142	Thermal burn	FAERS: 2		US FAERS
143	Unmasking of previously unidentified disease	FAERS: 2		US FAERS
144	Urinary Retention	FAERS: 2		US FAERS
145	Urticaria	FAERS: 2 Canada Vigilance: 2		Canada Vigilance SIDER US FAERS
146	Vulvovaginal burning sensation	FAERS: 2		US FAERS
147	Wrong drug administered	FAERS: 2		US FAERS
148	Acute Coronary Syndrome	FAERS: 1	10958127 15005775	CTD US FAERS
149	Alanine Aminotransferase Increased	FAERS: 1		US FAERS
150	Alopecia	FAERS: 1		US FAERS
151	Anal abscess	FAERS: 1		US FAERS
152	Anaphylactic shock	FAERS: 1 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
153	Angioedema	FAERS: 1	20084849	CTD SIDER US FAERS
154	Anxiety	FAERS: 1 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
155	Aphasia	FAERS: 1		US FAERS
156	Aphonia	FAERS: 1		US FAERS
157	Application site eczema	FAERS: 1		US FAERS
158	Application site erosion	FAERS: 1		US FAERS
159	Application site exfoliation	FAERS: 1		US FAERS
160	Application site scar	FAERS: 1		US FAERS
161	Application site urticaria	FAERS: 1		US FAERS
162	Application site warmth	FAERS: 1		US FAERS
163	Arthralgia	FAERS: 1		US FAERS
164	Arthritis	FAERS: 1		OFFSIDES US FAERS
165	Asthma	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
166	Atopy	FAERS: 1		US FAERS
167	Bladder dysfunction	FAERS: 1		US FAERS
168	Blepharospasm	FAERS: 1		US FAERS
169	Blood creatine increased	FAERS: 1		US FAERS
170	Breakthrough Pain	FAERS: 1		US FAERS
171	Bronchitis	FAERS: 1		OFFSIDES US FAERS
172	Bruxism	FAERS: 1		OFFSIDES US FAERS
173	Carpal Tunnel Syndrome	FAERS: 1		US FAERS
174	Chills	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
175	Colitis	FAERS: 1		US FAERS
176	Contraindicated product prescribed	FAERS: 1		US FAERS
177	Depressed mood	FAERS: 1		US FAERS
178	Dermatitis Herpetiformis	FAERS: 1		US FAERS
179	Device computer issue	FAERS: 1		US FAERS
180	Device occlusion	FAERS: 1		US FAERS
181	Documented hypersensitivity to administered drug	FAERS: 1		US FAERS
182	Drug Tolerance	FAERS: 1 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
183	Drug administered to patient of inappropriate age	FAERS: 1		US FAERS
184	Drug dispensed to wrong patient	FAERS: 1		US FAERS
185	Drug exposure during pregnancy	FAERS: 1		US FAERS
186	Drug label confusion	FAERS: 1		US FAERS
187	Drug prescribing error	FAERS: 1		US FAERS
188	Dyspepsia	FAERS: 1 Canada Vigilance: 2		Canada Vigilance OFFSIDES US FAERS
189	Eczema	FAERS: 1 Canada Vigilance: 2		Canada Vigilance OFFSIDES SIDER US FAERS
190	Electrocardiogram abnormal	FAERS: 1		US FAERS
191	Epigastric discomfort	FAERS: 1		US FAERS
192	Erectile dysfunction	FAERS: 1	1737261	CTD US FAERS
193	Erection increased	FAERS: 1		US FAERS
194	Excoriation	FAERS: 1		OFFSIDES US FAERS
195	Facial Pain	FAERS: 1		US FAERS
196	Fibromyalgia	FAERS: 1		US FAERS
197	Frustration	FAERS: 1		US FAERS
198	General physical health deterioration	FAERS: 1		US FAERS
199	Glaucoma	FAERS: 1		US FAERS
200	Head Banging	FAERS: 1		US FAERS
201	Head discomfort	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
202	Hyperacusis	FAERS: 1		US FAERS
203	Hypertensive crisis	FAERS: 1		US FAERS
204	Inadequate analgesia	FAERS: 1		US FAERS
205	Inappropriate schedule of drug administration	FAERS: 1		US FAERS
206	Incoherent	FAERS: 1		US FAERS
207	Incontinence	FAERS: 1		OFFSIDES US FAERS
208	Incorrect dose administered by device	FAERS: 1		US FAERS
209	Incorrect route of product administration	FAERS: 1		US FAERS
210	Infarction	FAERS: 1		US FAERS
211	Infection	FAERS: 1		SIDER US FAERS
212	Influenza	FAERS: 1		US FAERS
213	Intentional dose omission	FAERS: 1		US FAERS
214	Intercepted drug dispensing error	FAERS: 1		US FAERS
215	Joint injury	FAERS: 1		OFFSIDES US FAERS
216	Joint swelling	FAERS: 1		US FAERS
217	Leukocytosis	FAERS: 1		US FAERS
218	Limb operation	FAERS: 1		US FAERS
219	Malignant Hypertension	FAERS: 1		OFFSIDES US FAERS
220	Maternal exposure during pregnancy	FAERS: 1		US FAERS
221	Mechanical complication of implant	FAERS: 1		US FAERS
222	Metanephrine urine increased	FAERS: 1		US FAERS
223	Migraine with Aura	FAERS: 1	11168608 15288408 16024898	CTD US FAERS
224	Mood swings	FAERS: 1		US FAERS
225	Myocarditis	FAERS: 1		US FAERS
226	Neck Pain	FAERS: 1		US FAERS
227	Neonatal disorder	FAERS: 1		US FAERS
228	Nephrolithiasis	FAERS: 1		OFFSIDES US FAERS
229	Nonspecific reaction	FAERS: 1		US FAERS
230	Normetanephrine urine increased	FAERS: 1		US FAERS
231	Ocular discomfort	FAERS: 1		US FAERS
232	Oliguria	FAERS: 1		US FAERS
233	Oral papule	FAERS: 1		US FAERS
234	Osteoporosis	FAERS: 1		US FAERS
235	Oxygen saturation increased	FAERS: 1		US FAERS
236	Pancreatitis	FAERS: 1		OFFSIDES US FAERS
237	Papule	FAERS: 1		US FAERS
238	Poor quality product administered	FAERS: 1		US FAERS
239	Poor quality sleep	FAERS: 1		US FAERS
240	Prescription drug used without a prescription	FAERS: 1		US FAERS
241	Procedural complication	FAERS: 1		US FAERS
242	Product administered to patient of inappropriate age	FAERS: 1		US FAERS
243	Product administration error	FAERS: 1		US FAERS
244	Product barcode issue	FAERS: 1		US FAERS
245	Product complaint	FAERS: 1 Canada Vigilance: 4		Canada Vigilance US FAERS
246	Product contamination physical	FAERS: 1		US FAERS
247	Product expiration date issue	FAERS: 1		US FAERS
248	Product packaging confusion	FAERS: 1		US FAERS
249	Product shape issue	FAERS: 1		US FAERS
250	Product tampering	FAERS: 1		US FAERS
251	Pulmonary arterial pressure decreased	FAERS: 1		US FAERS
252	Purulence	FAERS: 1		US FAERS
253	Purulent discharge	FAERS: 1		US FAERS
254	Respiratory Depression	FAERS: 1		US FAERS
255	Respiratory Failure	FAERS: 1		US FAERS
256	Respiratory arrest	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
257	Respiratory distress	FAERS: 1		US FAERS
258	Retching	FAERS: 1		US FAERS
259	Retinal Detachment	FAERS: 1		US FAERS
260	Retinal Vein Occlusion	FAERS: 1		US FAERS
261	Right ventricular failure	FAERS: 1		US FAERS
262	Rubber sensitivity	FAERS: 1		US FAERS
263	Screaming	FAERS: 1		US FAERS
264	Skin Ulcer	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
265	Skin test positive	FAERS: 1		US FAERS
266	Sneezing	FAERS: 1		US FAERS
267	Soft tissue necrosis	FAERS: 1		US FAERS
268	Subcutaneous Abscess	FAERS: 1		US FAERS
269	Sudden Cardiac Death	FAERS: 1		US FAERS
270	Tablet physical issue	FAERS: 1		US FAERS
271	Tension Headache	FAERS: 1		US FAERS
272	Therapeutic product ineffective	FAERS: 1		US FAERS
273	Therapeutic response unexpected with drug substitution	FAERS: 1		US FAERS
274	Therapy cessation	FAERS: 1		US FAERS
275	Throat cancer	FAERS: 1		US FAERS
276	Tinnitus	FAERS: 1		OFFSIDES US FAERS
277	Tongue blistering	FAERS: 1		US FAERS
278	Trigeminal Neuralgia	FAERS: 1		US FAERS
279	Unevaluable event	FAERS: 1		US FAERS
280	Vasospasm	FAERS: 1		US FAERS
281	Visual Impairment	FAERS: 1		SIDER US FAERS
282	Weight decreased	FAERS: 1		US FAERS
283	West Nile viral infection	FAERS: 1		US FAERS
284	Wrong patient received medication	FAERS: 1		US FAERS
285	Abdominal Pain			SIDER
286	Abdominal colic			SIDER
287	Abducens Nerve Diseases		1903583 6416043	CTD
288	Abscess			OFFSIDES
289	Acid reflux			OFFSIDES
290	Acidosis			OFFSIDES
291	Acquired porphyria			OFFSIDES
292	Actinic keratosis			OFFSIDES
293	Actinomycosis			OFFSIDES
294	Acute kidney injury		12243603	CTD
295	Agitation			SIDER
296	Akinesia			OFFSIDES
297	Altitude Sickness		18800963	CTD
298	Alveoloplasty			OFFSIDES
299	Amnesia, Transient Global		18349207	CTD
300	Amphetamines			OFFSIDES
301	Amyloidosis			OFFSIDES
302	Anaphylactoid Reaction	Canada Vigilance: 2		Canada Vigilance SIDER
303	Angina pectoris aggravated			SIDER
304	Angina, Unstable		3127076 3137075	CTD
305	Anuria		8225663	CTD
306	Aortic Aneurysm			OFFSIDES
307	Apnea		2124178	CTD OFFSIDES
308	Application site inflammation	Canada Vigilance: 1		Canada Vigilance
309	Arterial insufficiency			OFFSIDES
310	Arthropathy			OFFSIDES
311	Atherosclerosis			OFFSIDES
312	Aura			OFFSIDES
313	Biopsy bone abnormal			OFFSIDES
314	Blood Glucose			OFFSIDES
315	Blood Platelet Disorders		7625621 9389267	CTD
316	Blood and lymphatic system disorders			SIDER
317	Blood cholesterol			OFFSIDES
318	Blood creatine phosphokinase increased			OFFSIDES
319	Blood glucose decreased			OFFSIDES
320	Blood glucose fluctuation			OFFSIDES
321	Blood iron increased			OFFSIDES
322	Blood potassium increased			OFFSIDES
323	Blood potassium			OFFSIDES
324	Blood pressure inadequately controlled			OFFSIDES
325	Blood sodium			OFFSIDES
326	Blood thyroid stimulating hormone			OFFSIDES
327	Blood triglycerides increased			OFFSIDES
328	Brain Edema		18800963	CTD
329	Brain Ischemia		8401937	CTD
330	Brain natriuretic peptide increased			OFFSIDES
331	Bundle-Branch Block		10475830	CTD
332	Cardiac Flutter			OFFSIDES
333	Central nervous system lesion			OFFSIDES
334	Cerebral Hemorrhage		1458106	CTD
335	Cerebral Palsy			OFFSIDES
336	Cerebral atrophy			OFFSIDES
337	Cervicobrachial syndrome			OFFSIDES
338	Chemical burn of skin	Canada Vigilance: 1		Canada Vigilance
339	Chemical burns of eye	Canada Vigilance: 1		Canada Vigilance
340	Choking sensation			OFFSIDES
341	Cholangiocarcinoma		8968066	CTD
342	Cholecystitis infective			OFFSIDES
343	Cholecystitis			OFFSIDES
344	Choroid Diseases		12055481	CTD
345	Chromaturia			OFFSIDES
346	Chronic Obstructive Airway Disease			OFFSIDES
347	Cirrhosis			OFFSIDES
348	Cluster Headache		View details 1446986 3100476 3179690 7540279 8895232 10329285 12807519 14728706 19501166	CTD
349	Colectomy			OFFSIDES
350	Confabulation			OFFSIDES
351	Congenital tricuspid valve incompetence			OFFSIDES
352	Cor pulmonale			OFFSIDES
353	Coronary Occlusion		8164149	CTD
354	Coronary Stenosis		3110237 3421167	CTD
355	Creatinine renal clearance decreased			OFFSIDES
356	Cubital Tunnel Syndrome			OFFSIDES
357	Culture wound positive			OFFSIDES
358	Cyanosis	Canada Vigilance: 2		Canada Vigilance SIDER
359	Deafness			OFFSIDES
360	Debridement			OFFSIDES
361	Decreased Libido			OFFSIDES
362	Demyelination			OFFSIDES
363	Depressed Level of Consciousness	Canada Vigilance: 1		Canada Vigilance
364	Dermatitis	Canada Vigilance: 2		Canada Vigilance SIDER
365	Device breakage	Canada Vigilance: 1		Canada Vigilance
366	Device deployment issue	Canada Vigilance: 1		Canada Vigilance
367	Device ineffective	Canada Vigilance: 1		Canada Vigilance
368	Device physical property issue	Canada Vigilance: 1		Canada Vigilance
369	Device use error	Canada Vigilance: 1		Canada Vigilance
370	Diabetes			OFFSIDES
371	Diabetes mellitus inadequate control			OFFSIDES
372	Diarrhea			OFFSIDES
373	Diplopia		6416043	CTD
374	Diverticulum			OFFSIDES
375	Drowsiness			SIDER
376	Drug withdrawal headache			OFFSIDES
377	Dysmenorrhea		11915580	CTD
378	Dyspnea		12771913 15564710	CTD
379	Edema		1425939 11701602	CTD
380	Electrocardiogram ST-T change			OFFSIDES
381	Emotional distress			OFFSIDES
382	Enterococcal infection			OFFSIDES
383	Enzyme abnormality			OFFSIDES
384	Escherichia urinary tract infection			OFFSIDES
385	Extravasation of Diagnostic and Therapeutic Materials		2865615	CTD
386	Eye Infection			OFFSIDES
387	Factor VIII inhibition			OFFSIDES
388	Fatty Liver			OFFSIDES
389	Feeling Cold			OFFSIDES
390	Fixed drug eruption			SIDER
391	Flat affect			OFFSIDES
392	Flatulence			OFFSIDES
393	Fluid overload			OFFSIDES
394	Frostbite		18800963	CTD
395	Gastrointestinal Diseases		3985522	CTD
396	Gastrointestinal Pain			SIDER
397	Gastrointestinal infection			OFFSIDES
398	Gene Mutation			OFFSIDES
399	Genital burning sensation			OFFSIDES
400	Genital erosion			OFFSIDES
401	Granuloma			OFFSIDES
402	Headache Disorders, Primary		10960046	CTD
403	Heart Block		6407806	CTD
404	Heart failure		View details 2117845 6430054 16440063 17075217	CTD
405	Hematuria		8225663	CTD
406	Hemiplegia		6792715	CTD
407	Hemorrhage		8225663	CTD
408	Hemorrhoids		7736873	CTD
409	Heparin-induced thrombocytopenia			OFFSIDES
410	Hepatitis		12243603	CTD OFFSIDES
411	Hyperalgesia		View details 1425939 10422945 11911994 12208318 14506907 15142344 15936504 16507304 18761334 19489890 19515121 25290014	CTD
412	Hypercapnia			OFFSIDES
413	Hyperemia		View details 7586405 12860835 17345787 17929130	CTD
414	Hyperpnea			SIDER
415	Hypertrophic Cardiomyopathy			OFFSIDES
416	Hyperventilation			SIDER
417	Hypesthesia		9648986	CTD
418	Hypotension, Orthostatic		8634922 10696890	CTD
419	Hypotensive			SIDER
420	Hypoxemia			SIDER
421	Iatrogenic injury			OFFSIDES
422	Immobile			SIDER
423	Impaired gastric emptying			OFFSIDES
424	Implantable defibrillator insertion			OFFSIDES
425	Infestation			SIDER
426	Infusion site mobility decreased			OFFSIDES
427	Injection site dermatitis			OFFSIDES
428	Injection site urticaria			OFFSIDES
429	Intention tremor			OFFSIDES
430	Intestinal Obstruction	Canada Vigilance: 1		Canada Vigilance
431	Intracranial Hypertension		1448188 3928252 6775054	CTD
432	Intraoperative Complications		9990214	CTD
433	Iodine uptake increased			OFFSIDES
434	Ischemia		9523545	CTD
435	Kidney Failure			OFFSIDES
436	Left Ventricular Hypertrophy			OFFSIDES
437	Left atrial dilatation			OFFSIDES
438	Life expectancy shortened			OFFSIDES
439	Lightheadedness			SIDER
440	Lip erosion			OFFSIDES
441	Liver Neoplasms, Experimental		8968066	CTD
442	Localised skin reaction			SIDER
443	Low Back Pain		11915580	CTD
444	Lupus pneumonitis			OFFSIDES
445	Lymphocyte percentage decreased			OFFSIDES
446	Macule	Canada Vigilance: 1		Canada Vigilance
447	Malignant ascites			OFFSIDES
448	Malignant tumour excision			OFFSIDES
449	Memory Disorders		19923525	CTD
450	Metabolic acidosis			OFFSIDES
451	Methemoglobinemia		3537620	CTD
452	Migraine Disorders		View details 2515254 3110103 8241457 8742685 8866624 11701602 15182958 15689192 18956709 19438913 19457613 21235591	CTD
453	Mucosal erosion			OFFSIDES
454	Muscle Weakness			OFFSIDES
455	Muscle necrosis			OFFSIDES
456	Myelodysplasia			OFFSIDES
457	Myeloma recurrence			OFFSIDES
458	Myocardial Ischemia		View details 102330 803231 820103 1575347 3123560 3304958 8511251 8706062 8974441 9188292 9412885 9562942 10719974 11554966 12766388 14968347 15087660 15242440	CTD
459	Myocardial Reperfusion Injury		9188292	CTD
460	Nephrogenic Fibrosing Dermopathy			OFFSIDES
461	Nervousness	Canada Vigilance: 1		Canada Vigilance
462	Neuralgia			OFFSIDES
463	Nodular regenerative hyperplasia			OFFSIDES
464	Nodule on extremity			OFFSIDES
465	Occupational Diseases		3917307 6442006 11395995	CTD
466	Oral mucosal exfoliation			OFFSIDES
467	Orthopnea			OFFSIDES
468	Osteomyelitis			OFFSIDES
469	Pain, Postoperative		15832742	CTD
470	Pallor	Canada Vigilance: 1		Canada Vigilance OFFSIDES SIDER
471	Papilledema		1903583	CTD
472	Paroxysmal Hemicrania		17645760	CTD
473	Pericarditis lupus			OFFSIDES
474	Pericarditis			OFFSIDES
475	Peripheral swelling	Canada Vigilance: 1		Canada Vigilance
476	Pharyngeal swelling	Canada Vigilance: 1		Canada Vigilance
477	Pharyngitis			SIDER
478	Phlebitis		2865615	CTD
479	Pneumothorax			OFFSIDES
480	Post procedural fistula			OFFSIDES
481	Post procedural infection			OFFSIDES
482	Postoperative Complications		2515460 6804108 11554966	CTD
483	Postoperative ileus			OFFSIDES
484	Pre-Eclampsia		17322376	CTD
485	Product lot number issue	Canada Vigilance: 1		Canada Vigilance
486	Protein total increased			OFFSIDES
487	Pseudotumor Cerebri		1903583	CTD
488	Pulmonary Edema		9645186	CTD
489	Pulmonary Hypertension			OFFSIDES
490	Pulmonary congestion			OFFSIDES
491	Purpura	Canada Vigilance: 1		Canada Vigilance
492	Quality of life decreased			OFFSIDES
493	Rales			OFFSIDES
494	Rash erythematous	Canada Vigilance: 5		Canada Vigilance
495	Rebound hypertension			SIDER
496	Rectal polyp			OFFSIDES
497	Redness			SIDER
498	Reflex bradycardia			SIDER
499	Reflex tachycardia			SIDER
500	Renal cyst			OFFSIDES
501	Reperfusion Injury		8869312	CTD
502	Restrictive pulmonary disease			OFFSIDES
503	Retinal Artery Occlusion		12055481	CTD
504	Retrosternal discomfort			SIDER
505	Rhabdomyolysis		12243603	CTD
506	Rhinitis			SIDER
507	Rhonchi			OFFSIDES
508	Seizures		17543232	CTD
509	Sequestrectomy			OFFSIDES
510	Sinusitis			OFFSIDES
511	Sjogren's Syndrome			OFFSIDES
512	Skin graft failure			OFFSIDES
513	Skin laceration	Canada Vigilance: 1		Canada Vigilance
514	Skin lesion	Canada Vigilance: 1		Canada Vigilance OFFSIDES
515	Skin necrosis			OFFSIDES
516	Skin reaction	Canada Vigilance: 4		Canada Vigilance SIDER
517	Spasm		9431903 11016328 11379694	CTD
518	Speech Disorders		3928252	CTD
519	Sphincter of Oddi Dysfunction		9431903 11379694	CTD
520	Splenic Infarction			OFFSIDES
521	Stevens-Johnson Syndrome			OFFSIDES
522	Stomatitis			SIDER
523	Stupor	Canada Vigilance: 1		Canada Vigilance
524	Subarachnoid Hemorrhage		15198873	CTD
525	Substance Withdrawal Syndrome		View details 803766 2502009 3150959 4627365 6401366 6408745 9316524 11228088	CTD
526	Sweating			SIDER
527	Syringe issue	Canada Vigilance: 1		Canada Vigilance
528	Tachycardia, Ventricular		10719974	CTD
529	Tachyphylaxis	Canada Vigilance: 1		Canada Vigilance
530	Terminal state			OFFSIDES
531	Therapeutic product effect decreased	Canada Vigilance: 4		Canada Vigilance
532	Throbbing Headache			SIDER
533	Thrombophlebitis		8748367	CTD
534	Thrombosis in device			OFFSIDES
535	Tobacco user			OFFSIDES
536	Tolerance development			SIDER
537	Troponin increased			OFFSIDES
538	Ulcer			OFFSIDES
539	Urinary tract infection staphylococcal			OFFSIDES
540	Vascular bypass graft			OFFSIDES
541	Vasodilation procedure			SIDER
542	Vasodilation			SIDER
543	Ventricular Dysfunction, Left		View details 820103 1836097 6160553 15242440	CTD
544	Vision Disorders		1903583	CTD
545	Visual disturbance			SIDER
546	Vulvovaginal pain	Canada Vigilance: 1		Canada Vigilance
547	Water Intoxication			OFFSIDES
548	Weight Gain			OFFSIDES
549	Withdrawal hypertension			SIDER
550	Wound dehiscence			OFFSIDES
551	anaphylaxis		20084849	CTD
552	effusion			OFFSIDES
553	fibroma			OFFSIDES
554	furuncle			OFFSIDES
555	nervous system disorder			SIDER
556	skin abrasion	Canada Vigilance: 1		Canada Vigilance

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