Clomipramine
(WIMWMKZEIBHDTH-UHFFFAOYSA-N)
Structure
- SMILES
- CN(CCCN1c2ccccc2CCc2c1cc(Cl)cc2)C.Cl
- Molecular Formula:
- C19H24Cl2N2
- Molecular Weight:
- 351.313
- Log P:
- 5.3954
- Hydrogen Bond Acceptor:
- 1
- Hydrogen Bond Donor:
- 1
- TPSA:
- 6.48
- CAS Number(s):
- 17321-77-6
Synonym(s)
1.
Clomipramine
2.
Chlorimipramine
3.
Anafranil
4.
Chlomipramine
5.
Clomipramine Hydrochloride
6.
Clomipramine Maleate (1:1)
7.
Clomipramine Monohydrochloride
8.
Hydiphen
9.
Hydrochloride, Clomipramine
10.
Monohydrochloride, Clomipramine
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug exposure during pregnancy | FAERS: 11 | US FAERS | |
| 2 | Anxiety | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 3 | Maternal exposure during pregnancy | FAERS: 7 | US FAERS | |
| 4 | Drug ineffective | FAERS: 5 Canada Vigilance: 9 | Canada Vigilance US FAERS | |
| 5 | Pre-Eclampsia | FAERS: 5 | US FAERS | |
| 6 | Dizziness | FAERS: 4 Canada Vigilance: 10 | Canada Vigilance US FAERS | |
| 7 | Nausea | FAERS: 4 Canada Vigilance: 9 | Canada Vigilance US FAERS | |
| 8 | Pharmaceutical product complaint | FAERS: 4 | US FAERS | |
| 9 | Tremor | FAERS: 4 Canada Vigilance: 10 | Canada Vigilance US FAERS | |
| 10 | Drug exposure via breast milk | FAERS: 3 | US FAERS | |
| 11 | Drug toxicity | FAERS: 3 | US FAERS | |
| 12 | Pregnancy | FAERS: 3 | US FAERS | |
| 13 | Vomiting | FAERS: 3 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 14 | Antiphospholipid Syndrome | FAERS: 2 | US FAERS | |
| 15 | Blood pH decreased | FAERS: 2 | US FAERS | |
| 16 | Blood potassium decreased | FAERS: 2 | US FAERS | |
| 17 | Constipation | FAERS: 2 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 18 | Dehydration | FAERS: 2 | US FAERS | |
| 19 | Depressed Level of Consciousness | FAERS: 2 | US FAERS | |
| 20 | Diabetes Mellitus | FAERS: 2 | US FAERS | |
| 21 | Drug withdrawal syndrome | FAERS: 2 | US FAERS | |
| 22 | Hypoventilation | FAERS: 2 | US FAERS | |
| 23 | Mydriasis | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 24 | Neonatal disorder | FAERS: 2 | US FAERS | |
| 25 | Neonatal tachycardia | FAERS: 2 | US FAERS | |
| 26 | Obsessive-Compulsive Disorder | FAERS: 2 | US FAERS | |
| 27 | Opisthotonus | FAERS: 2 | US FAERS | |
| 28 | PCO2 increased | FAERS: 2 | US FAERS | |
| 29 | Palpitations | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 30 | Pancreatitis | FAERS: 2 | US FAERS | |
| 31 | Serotonin Syndrome | FAERS: 2 | US FAERS | |
| 32 | Somnolence | FAERS: 2 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 33 | Tachycardia | FAERS: 2 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 34 | Throat irritation | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 35 | Weight decreased | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 36 | Abdominal Pain | FAERS: 1 | US FAERS | |
| 37 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 38 | Agitation | FAERS: 1 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 39 | Agranulocytosis | FAERS: 1 | US FAERS | |
| 40 | Angioedema | FAERS: 1 | US FAERS | |
| 41 | Anorexia | FAERS: 1 | US FAERS | |
| 42 | Anuria | FAERS: 1 | US FAERS | |
| 43 | Apallic syndrome | FAERS: 1 | US FAERS | |
| 44 | Aspartate Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 45 | Asthenia | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 46 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 47 | Base excess decreased | FAERS: 1 | US FAERS | |
| 48 | Blood chloride decreased | FAERS: 1 | US FAERS | |
| 49 | Blood growth hormone increased | FAERS: 1 | US FAERS | |
| 50 | Blood prolactin increased | FAERS: 1 | US FAERS | |
| 51 | Blood testosterone increased | FAERS: 1 | US FAERS | |
| 52 | Bruxism | FAERS: 1 | US FAERS | |
| 53 | Cerebral cyst | FAERS: 1 | US FAERS | |
| 54 | Chemical burn of gastrointestinal tract | FAERS: 1 | US FAERS | |
| 55 | Choking | FAERS: 1 | US FAERS | |
| 56 | Clonus | FAERS: 1 | US FAERS | |
| 57 | Cold sweat | FAERS: 1 | US FAERS | |
| 58 | Completed Suicide | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 59 | Congenital cerebral cyst | FAERS: 1 | US FAERS | |
| 60 | Crying | FAERS: 1 | US FAERS | |
| 61 | Cyanosis | FAERS: 1 | US FAERS | |
| 62 | Delayed delivery | FAERS: 1 | US FAERS | |
| 63 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 64 | Drug level decreased | FAERS: 1 | US FAERS | |
| 65 | Dyspepsia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 66 | Emotional disorder | FAERS: 1 | US FAERS | |
| 67 | Fatigue | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 68 | Feeding disorder neonatal | FAERS: 1 | US FAERS | |
| 69 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 70 | Female sexual arousal disorder | FAERS: 1 | US FAERS | |
| 71 | Gastroenteritis | FAERS: 1 | US FAERS | |
| 72 | Gestational Diabetes | FAERS: 1 | US FAERS | |
| 73 | Headache | FAERS: 1 Canada Vigilance: 9 | Canada Vigilance US FAERS | |
| 74 | Hepatomegaly | FAERS: 1 | US FAERS | |
| 75 | Hyperemesis Gravidarum | FAERS: 1 | US FAERS | |
| 76 | Hyperreflexia | FAERS: 1 | US FAERS | |
| 77 | Hypokinesia | FAERS: 1 | US FAERS | |
| 78 | Immune thrombocytopenic purpura | FAERS: 1 | US FAERS | |
| 79 | Intentional drug misuse | FAERS: 1 | US FAERS | |
| 80 | Leukopenia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 81 | Low birth weight baby | FAERS: 1 | US FAERS | |
| 82 | Medication Error | FAERS: 1 | US FAERS | |
| 83 | Multiple drug overdose | FAERS: 1 | US FAERS | |
| 84 | Muscle Cramp | FAERS: 1 | US FAERS | |
| 85 | Muscle Rigidity | FAERS: 1 | US FAERS | |
| 86 | Myocardial Infarction | FAERS: 1 | US FAERS | |
| 87 | Nephrotic Syndrome | FAERS: 1 | US FAERS | |
| 88 | Nervousness | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 89 | Neuroleptic Malignant Syndrome | FAERS: 1 | US FAERS | |
| 90 | Neutrophil count decreased | FAERS: 1 | US FAERS | |
| 91 | Obsessive thoughts | FAERS: 1 | US FAERS | |
| 92 | Pallor | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 93 | Pleurothotonus | FAERS: 1 | US FAERS | |
| 94 | Pneumonitis | FAERS: 1 | US FAERS | |
| 95 | Polydipsia | FAERS: 1 | US FAERS | |
| 96 | Prescribed overdose | FAERS: 1 | US FAERS | |
| 97 | Product quality issue | FAERS: 1 | US FAERS | |
| 98 | Product substitution issue | FAERS: 1 | US FAERS | |
| 99 | Product use complaint | FAERS: 1 | US FAERS | |
| 100 | Pulmonary thrombosis | FAERS: 1 | US FAERS | |
| 101 | Retching | FAERS: 1 | US FAERS | |
| 102 | Sepsis | FAERS: 1 | US FAERS | |
| 103 | Sneezing | FAERS: 1 | US FAERS | |
| 104 | Staring | FAERS: 1 | US FAERS | |
| 105 | Suicide attempt | FAERS: 1 | US FAERS | |
| 106 | Therapeutic response unexpected with drug substitution | FAERS: 1 | US FAERS | |
| 107 | Thrombosis | FAERS: 1 | US FAERS | |
| 108 | Urinary Retention | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 109 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 110 | Vertigo | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 111 | Water Intoxication | FAERS: 1 | US FAERS | |
| 112 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 113 | Wrong technique in product usage process | FAERS: 1 | US FAERS | |
| 114 | Yawning | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 115 | Abdominal discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 116 | Alcohol interaction | Canada Vigilance: 1 | Canada Vigilance | |
| 117 | Alopecia | Canada Vigilance: 1 | Canada Vigilance | |
| 118 | Amnesia | Canada Vigilance: 1 | Canada Vigilance | |
| 119 | Anaphylactoid Reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 120 | Angina Pectoris | Canada Vigilance: 1 | Canada Vigilance | |
| 121 | Anorgasmia | Canada Vigilance: 1 | Canada Vigilance | |
| 122 | Ataxia | Canada Vigilance: 1 | Canada Vigilance | |
| 123 | Burning sensation | Canada Vigilance: 2 | Canada Vigilance | |
| 124 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 125 | Chest discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 126 | Chills | Canada Vigilance: 1 | Canada Vigilance | |
| 127 | Diplopia | Canada Vigilance: 1 | Canada Vigilance | |
| 128 | Disorientation | Canada Vigilance: 5 | Canada Vigilance | |
| 129 | Drug Dependence | Canada Vigilance: 1 | Canada Vigilance | |
| 130 | Drug level increased | Canada Vigilance: 1 | Canada Vigilance | |
| 131 | Dystonia | Canada Vigilance: 1 | Canada Vigilance | |
| 132 | Electrocardiogram abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 133 | Erectile dysfunction | Canada Vigilance: 6 | Canada Vigilance | |
| 134 | Euphoric mood | Canada Vigilance: 1 | Canada Vigilance | |
| 135 | Feeling Cold | Canada Vigilance: 1 | Canada Vigilance | |
| 136 | Feeling jittery | Canada Vigilance: 1 | Canada Vigilance | |
| 137 | Feeling of body temperature change | Canada Vigilance: 1 | Canada Vigilance | |
| 138 | Flushing | Canada Vigilance: 3 | Canada Vigilance | |
| 139 | Hirsutism | Canada Vigilance: 2 | Canada Vigilance | |
| 140 | Hyperacusis | Canada Vigilance: 1 | Canada Vigilance | |
| 141 | Hypomania | Canada Vigilance: 1 | Canada Vigilance | |
| 142 | Hypotension | Canada Vigilance: 3 | Canada Vigilance | |
| 143 | Inappropriate affect | Canada Vigilance: 1 | Canada Vigilance | |
| 144 | Injection Site Reaction | Canada Vigilance: 2 | Canada Vigilance | |
| 145 | Laryngospasm | Canada Vigilance: 2 | Canada Vigilance | |
| 146 | Memory impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 147 | Mental impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 148 | Paranoia | Canada Vigilance: 3 | Canada Vigilance | |
| 149 | Pruritus | Canada Vigilance: 2 | Canada Vigilance | |
| 150 | Pulmonary Embolism | Canada Vigilance: 1 | Canada Vigilance | |
| 151 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 152 | Rash erythematous | Canada Vigilance: 2 | Canada Vigilance | |
| 153 | Sedation complication | Canada Vigilance: 1 | Canada Vigilance | |
| 154 | Sexual Dysfunction | Canada Vigilance: 2 | Canada Vigilance | |
| 155 | Stomatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 156 | Stupor | Canada Vigilance: 1 | Canada Vigilance | |
| 157 | Syncope | Canada Vigilance: 4 | Canada Vigilance | |
| 158 | Temperature intolerance | Canada Vigilance: 1 | Canada Vigilance | |
| 159 | Tension | Canada Vigilance: 1 | Canada Vigilance | |
| 160 | Therapeutic response unexpected | Canada Vigilance: 1 | Canada Vigilance | |
| 161 | Tinnitus | Canada Vigilance: 3 | Canada Vigilance | |
| 162 | Unevaluable event | Canada Vigilance: 1 | Canada Vigilance | |
| 163 | Urticaria | Canada Vigilance: 1 | Canada Vigilance | |
| 164 | Visual Impairment | Canada Vigilance: 2 | Canada Vigilance | |
| 165 | jaundice | Canada Vigilance: 1 | Canada Vigilance |
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