MetaADEDB 2.0 @ LMMD
Famciclovir
(GGXKWVWZWMLJEH-UHFFFAOYSA-N)
Structure
SMILES
CC(=O)OCC(CCn1cnc2c1nc(N)nc2)COC(=O)C
Type(s)
Approved; Investigational
ATC code(s)
J05AB09; S01AD07
Molecular Formula:
C14H19N5O4
Molecular Weight:
321.332
Log P:
1.1222
Hydrogen Bond Acceptor:
9
Hydrogen Bond Donor:
1
TPSA:
122.22
CAS Number(s):
104227-87-4
Synonym(s)
1.
Famciclovir
2.
9-(4-Acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine
3.
BRL 42810
4.
BRL-42810
5.
Famvir
6.
BRL42810
External Link(s)
MeSHD000077595
PubChem Compound3324
BindingDB50248001
50066502
ChEBI4974
CHEMBLCHEMBL880
DrugBankDB00426
DrugCentral1128
KEGGdr:D00317
Therapeutic Target DatabaseD0VT8P
ZINC1530635
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1MalaiseFAERS: 20
Canada Vigilance: 1
Canada Vigilance
US FAERS
2NauseaFAERS: 17
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
SIDER
US FAERS
3DizzinessFAERS: 16
Canada Vigilance: 3
Canada Vigilance
SIDER
US FAERS
4Drug ineffectiveFAERS: 16
Canada Vigilance: 18
Canada Vigilance
US FAERS
5VomitingFAERS: 15
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
6HeadacheFAERS: 13
Canada Vigilance: 6
Canada Vigilance
SIDER
US FAERS
7PalpitationsFAERS: 12
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
8AstheniaFAERS: 9OFFSIDES
SIDER
US FAERS
9PainFAERS: 9
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
US FAERS
10PruritusFAERS: 9
Canada Vigilance: 3
Canada Vigilance
SIDER
US FAERS
11Altered state of consciousnessFAERS: 7OFFSIDES
US FAERS
12AngioedemaFAERS: 7SIDER
US FAERS
13Blood creatinine increasedFAERS: 6
Canada Vigilance: 1
Canada Vigilance
US FAERS
14Burning sensationFAERS: 6US FAERS
15FatigueFAERS: 6SIDER
US FAERS
16Leukocytoclastic vasculitisFAERS: 6SIDER
US FAERS
17PallorFAERS: 6US FAERS
18RhabdomyolysisFAERS: 6US FAERS
19TachycardiaFAERS: 6US FAERS
20DisorientationFAERS: 5
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
21Feeling abnormalFAERS: 5SIDER
US FAERS
22NeuralgiaFAERS: 5
Canada Vigilance: 3
Canada Vigilance
US FAERS
23SomnolenceFAERS: 5
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
24SyncopeFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
25UrticariaFAERS: 5SIDER
US FAERS
26Choking sensationFAERS: 4OFFSIDES
US FAERS
27Drug exposure during pregnancyFAERS: 4US FAERS
28LethargyFAERS: 4US FAERS
29Maternal exposure during pregnancyFAERS: 4US FAERS
30OverdoseFAERS: 4US FAERS
31Product substitution issueFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
32TremorFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
33Abdominal discomfortFAERS: 3SIDER
US FAERS
34Acute kidney injuryFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
35AgitationFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
36ConstipationFAERS: 3SIDER
US FAERS
37DysarthriaFAERS: 3US FAERS
38Erythema MultiformeFAERS: 3
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
39GastritisFAERS: 3US FAERS
40Incorrect dose administeredFAERS: 3US FAERS
41Myocardial InfarctionFAERS: 3US FAERS
42Rash erythematousFAERS: 3US FAERS
43SepsisFAERS: 3US FAERS
44Skin lesionFAERS: 3US FAERS
45jaundiceFAERS: 3SIDER
US FAERS
46nervous system disorderFAERS: 3SIDER
US FAERS
47AbasiaFAERS: 2OFFSIDES
US FAERS
48Abdominal PainFAERS: 2OFFSIDES
SIDER
US FAERS
49Accidental overdoseFAERS: 2US FAERS
50Adverse eventFAERS: 2US FAERS
51Alanine Aminotransferase IncreasedFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
52AngerFAERS: 2US FAERS
53Angina PectorisFAERS: 2US FAERS
54AnuriaFAERS: 2US FAERS
55AnxietyFAERS: 2OFFSIDES
SIDER
US FAERS
56ArthralgiaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
57Back PainFAERS: 2SIDER
US FAERS
58Biopsy skin abnormalFAERS: 2US FAERS
59Blood creatine phosphokinase increasedFAERS: 2SIDER
US FAERS
60BradycardiaFAERS: 2US FAERS
61CandidiasisFAERS: 2US FAERS
62Cardiac ArrestFAERS: 2US FAERS
63Cerebrovascular accidentFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
64Chest discomfortFAERS: 2US FAERS
65Cold sweatFAERS: 2US FAERS
66Creatinine renal clearance decreasedFAERS: 2US FAERS
67DeafnessFAERS: 2OFFSIDES
US FAERS
68DementiaFAERS: 2US FAERS
69Depressed Level of ConsciousnessFAERS: 2US FAERS
70DermatitisFAERS: 2SIDER
US FAERS
71Disease ProgressionFAERS: 2US FAERS
72Disease recurrenceFAERS: 2US FAERS
73Dry skinFAERS: 2US FAERS
74DysuriaFAERS: 2US FAERS
75HypersensitivityFAERS: 2
Canada Vigilance: 2
Canada Vigilance
US FAERS
76Lymphocytic infiltrationFAERS: 2US FAERS
77Medication ErrorFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
78Memory impairmentFAERS: 2US FAERS
79Musculoskeletal PainFAERS: 2US FAERS
80Night sweatsFAERS: 2US FAERS
81PneumoniaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
82Product size issueFAERS: 2US FAERS
83Reduced facial expressionFAERS: 2US FAERS
84TinnitusFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
85Urinary RetentionFAERS: 2US FAERS
86Urinary tract infectionFAERS: 2US FAERS
87VasculitisFAERS: 2US FAERS
88Weight decreasedFAERS: 2US FAERS
89AcneFAERS: 1OFFSIDES
US FAERS
90AgeusiaFAERS: 1US FAERS
91Altered visual depth perceptionFAERS: 1US FAERS
92AnorexiaFAERS: 1OFFSIDES
SIDER
US FAERS
93Aspartate Aminotransferase IncreasedFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
94AsterixisFAERS: 1US FAERS
95AtaxiaFAERS: 1US FAERS
96AzoospermiaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
97Bipolar DisorderFAERS: 1US FAERS
98Blood amylase increasedFAERS: 1OFFSIDES
US FAERS
99Blood cholesterol increasedFAERS: 1US FAERS
100Blood glucose increasedFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
101Blood testosterone decreasedFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
102Blood urea increasedFAERS: 1OFFSIDES
US FAERS
103BronchitisFAERS: 1US FAERS
104BronchospasmFAERS: 1US FAERS
105CardiomegalyFAERS: 1US FAERS
106Cerebral InfarctionFAERS: 1US FAERS
107Cerebral artery occlusionFAERS: 1US FAERS
108Cerebral atrophyFAERS: 1OFFSIDES
US FAERS
109CheilitisFAERS: 1US FAERS
110ChillsFAERS: 1
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
111Complex partial seizuresFAERS: 1US FAERS
112ConjunctivitisFAERS: 1US FAERS
113DehydrationFAERS: 1OFFSIDES
US FAERS
114DeliriumFAERS: 1
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
115Depressed moodFAERS: 1US FAERS
116Drug effect incompleteFAERS: 1US FAERS
117Drug ineffective for unapproved indicationFAERS: 1US FAERS
118Emotional disorderFAERS: 1US FAERS
119EncephalitisFAERS: 1US FAERS
120EpilepsyFAERS: 1US FAERS
121EpistaxisFAERS: 1OFFSIDES
US FAERS
122ErythemaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
123Exfoliative rashFAERS: 1US FAERS
124Eye InfectionFAERS: 1US FAERS
125Feeling of body temperature changeFAERS: 1US FAERS
126FlushingFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
127FrustrationFAERS: 1US FAERS
128General physical health deteriorationFAERS: 1OFFSIDES
US FAERS
129Genital HerpesFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
130Head discomfortFAERS: 1US FAERS
131HepatotoxicityFAERS: 1US FAERS
132Herpes zoster meningomyelitisFAERS: 1US FAERS
133HyperkinesiaFAERS: 1US FAERS
134HyperpyrexiaFAERS: 1US FAERS
135HyperthyroidismFAERS: 1US FAERS
136Hypoaesthesia facialFAERS: 1US FAERS
137HypotensionFAERS: 1US FAERS
138HypothyroidismFAERS: 1US FAERS
139Idiosyncratic drug reactionFAERS: 1US FAERS
140Immune thrombocytopenic purpuraFAERS: 1US FAERS
141ImmunosuppressionFAERS: 1US FAERS
142Inappropriate schedule of drug administrationFAERS: 1US FAERS
143InflammationFAERS: 1US FAERS
144InfluenzaFAERS: 1US FAERS
145Limb discomfortFAERS: 1US FAERS
146Lipase increasedFAERS: 1SIDER
US FAERS
147Lymphocyte count increasedFAERS: 1US FAERS
148Mental status changesFAERS: 1OFFSIDES
US FAERS
149Metabolic acidosisFAERS: 1US FAERS
150Middle insomniaFAERS: 1US FAERS
151MyalgiaFAERS: 1SIDER
US FAERS
152MyoclonusFAERS: 1US FAERS
153NephrolithiasisFAERS: 1OFFSIDES
US FAERS
154Nerve injuryFAERS: 1US FAERS
155NervousnessFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
156Neutrophil count decreasedFAERS: 1US FAERS
157Ocular icterusFAERS: 1US FAERS
158Oropharyngeal blisteringFAERS: 1US FAERS
159PancreatitisFAERS: 1US FAERS
160Pharmaceutical product counterfeitFAERS: 1US FAERS
161PhotophobiaFAERS: 1US FAERS
162PleocytosisFAERS: 1US FAERS
163Product physical issueFAERS: 1US FAERS
164Product quality issueFAERS: 1US FAERS
165Product use in unapproved indicationFAERS: 1US FAERS
166PurpuraFAERS: 1US FAERS
167Renal cystFAERS: 1OFFSIDES
US FAERS
168Renal painFAERS: 1US FAERS
169Shock symptomFAERS: 1US FAERS
170Sinus TachycardiaFAERS: 1US FAERS
171Skin tightnessFAERS: 1US FAERS
172Stevens-Johnson SyndromeFAERS: 125811541CTD
SIDER
US FAERS
173SwellingFAERS: 1US FAERS
174Systemic Inflammatory Response SyndromeFAERS: 1US FAERS
175Throat irritationFAERS: 1US FAERS
176ThrombosisFAERS: 1US FAERS
177Transaminases increasedFAERS: 1OFFSIDES
US FAERS
178Transplantation complicationFAERS: 1US FAERS
179Ultrasound scan abnormalFAERS: 1US FAERS
180Unresponsive to stimuliFAERS: 1OFFSIDES
US FAERS
181Urinary IncontinenceFAERS: 1US FAERS
182Vaginal DischargeFAERS: 1US FAERS
183VerbigerationFAERS: 1US FAERS
184VertigoFAERS: 1US FAERS
185Viral upper respiratory tract infectionFAERS: 1US FAERS
186Visual disturbanceFAERS: 1US FAERS
187WheezingFAERS: 1US FAERS
188Wrong technique in product usage processFAERS: 1US FAERS
189XanthopsiaFAERS: 1US FAERS
190AbscessOFFSIDES
191Acid refluxOFFSIDES
192Acquired diaphragmatic eventrationOFFSIDES
193Activities of daily living impairedOFFSIDES
194Acute myocardial infarctionOFFSIDES
195Alanine aminotransferase abnormalOFFSIDES
196Allergy test positiveOFFSIDES
197Allergy to animalOFFSIDES
198AlopeciaOFFSIDES
199AlveoloplastyOFFSIDES
200AmnesiaOFFSIDES
201ArteriosclerosisOFFSIDES
202Arteriovenous fistula thrombosisOFFSIDES
203Arteriovenous graft thrombosisOFFSIDES
204ArthritisOFFSIDES
205AspergillomaOFFSIDES
206AtelectasisOFFSIDES
207AtherosclerosisOFFSIDES
208Atrial tachycardiaOFFSIDES
209BK virus infectionOFFSIDES
210BedriddenOFFSIDES
211Bile duct stent insertionOFFSIDES
212BlepharospasmOFFSIDES
213BlindnessCanada Vigilance: 1Canada Vigilance
214Blood alkaline phosphatase abnormalOFFSIDES
215Blood and lymphatic system disordersSIDER
216Blood arsenic increasedOFFSIDES
217Blood chloride decreasedOFFSIDES
218Blood cholesterolOFFSIDES
219Blood immunoglobulin A decreasedOFFSIDES
220Blood osmolarity increasedOFFSIDES
221Blood phosphorus increasedOFFSIDES
222Bone density decreasedOFFSIDES
223Bone lesionOFFSIDES
224Bone painOFFSIDES
225Bone scan abnormalOFFSIDES
226Brain ConcussionOFFSIDES
227Capillary Leak SyndromeOFFSIDES
228CellulitisOFFSIDES
229Chorea11440337CTD
230Clostridium colitisOFFSIDES
231Cluster HeadacheOFFSIDES
232ColitisCanada Vigilance: 1Canada Vigilance
233ConfabulationOFFSIDES
234Congenital tricuspid valve incompetenceOFFSIDES
235Conjunctival depositOFFSIDES
236Creatine Phosphokinase IncreasedSIDER
237CystoceleOFFSIDES
238Deafness NeurosensoryOFFSIDES
239DebridementOFFSIDES
240DemyelinationOFFSIDES
241Dental cariesOFFSIDES
242Diabetes InsipidusOFFSIDES
243Diabetic FootOFFSIDES
244DiarrheaOFFSIDES
245DiverticulitisOFFSIDES
246DiverticulosisOFFSIDES
247DiverticulumOFFSIDES
248Drug addictOFFSIDES
249Drug withdrawal headacheOFFSIDES
250DysgeusiaCanada Vigilance: 1Canada Vigilance
251DysgraphiaOFFSIDES
252DyspepsiaSIDER
253Emotional distressOFFSIDES
254Endometrial cancer stage IIOFFSIDES
255EnuresisOFFSIDES
256Enzyme abnormalitySIDER
257Epstein-Barr virus associated lymphoproliferative disorderOFFSIDES
258ExcoriationOFFSIDES
259ExophthalmosOFFSIDES
260Eye painCanada Vigilance: 1Canada Vigilance
OFFSIDES
261Febrile NeutropeniaOFFSIDES
262Feeling ColdCanada Vigilance: 1Canada Vigilance
263Flank PainOFFSIDES
264FlatulenceSIDER
265FormicationOFFSIDES
266Fungus serology test positiveOFFSIDES
267Gamma-Glutamyltransferase IncreasedSIDER
268GangreneOFFSIDES
269Gastrointestinal PainSIDER
270Graft infectionOFFSIDES
271GranulocytosisOFFSIDES
272HBV DNA increasedOFFSIDES
273HELLP SyndromeOFFSIDES
274Hepatic cancer metastaticOFFSIDES
275Hepatitis B, Chronic11792996CTD
276Hepatitis B

View details

CTD
277HepatitisOFFSIDES
278House dust allergyOFFSIDES
279HydronephrosisOFFSIDES
280Hypertensive emergencyOFFSIDES
281HypophagiaOFFSIDES
282HypoxiaOFFSIDES
283IncontinenceOFFSIDES
284Incorrect product administration durationCanada Vigilance: 3Canada Vigilance
285InfectionOFFSIDES
SIDER
286JC virus infectionOFFSIDES
287Joint Range of Motion DecreasedOFFSIDES
288Kidney FailureOFFSIDES
289Klebsiella sepsisOFFSIDES
290Latex allergyOFFSIDES
291Left atrial dilatationOFFSIDES
292Leukopenia neonatalOFFSIDES
293LeukopeniaSIDER
294Life expectancy shortenedOFFSIDES
295Lymphocyte count decreasedOFFSIDES
296Malignant neoplasm progressionOFFSIDES
297Mastication disorderOFFSIDES
298MucormycosisOFFSIDES
299Multi-organ disorderOFFSIDES
300Muscle flap operationOFFSIDES
301Musculoskeletal discomfortSIDER
302Musculoskeletal stiffnessCanada Vigilance: 1Canada Vigilance
303Mycobacterium avium complex immune restoration diseaseOFFSIDES
304NasopharyngitisSIDER
305NeurodermatitisOFFSIDES
306NeutropeniaSIDER
307OnychoclasisOFFSIDES
308OnycholysisOFFSIDES
309Oral mucosal eruptionCanada Vigilance: 1Canada Vigilance
310Orbital infectionOFFSIDES
311OsteomyelitisOFFSIDES
312OsteoporosisOFFSIDES
313OsteoradionecrosisOFFSIDES
314ParanoiaCanada Vigilance: 1Canada Vigilance
OFFSIDES
315ParophthalmiaOFFSIDES
316Patellofemoral Pain SyndromeOFFSIDES
317Pelvic kidneyOFFSIDES
318Perianal abscessOFFSIDES
319PeriodontitisOFFSIDES
320PharyngitisSIDER
321Pharyngolaryngeal PainOFFSIDES
SIDER
322Physical disabilityOFFSIDES
323Poor personal hygieneOFFSIDES
324Poor sucking reflexOFFSIDES
325Pre-EclampsiaOFFSIDES
326Primary sequestrumOFFSIDES
327Product contaminationOFFSIDES
328Product prescribing errorCanada Vigilance: 1Canada Vigilance
329Pulmonary HypertensionOFFSIDES
330Pulmonary InfarctionOFFSIDES
331Purulent dischargeOFFSIDES
332Renal tubular necrosisOFFSIDES
333RestlessnessCanada Vigilance: 1Canada Vigilance
334Retinal VasculitisOFFSIDES
335RhinorrheaOFFSIDES
336Right atrial dilatationOFFSIDES
337SequestrectomyOFFSIDES
338Sinus operationOFFSIDES
339SinusitisSIDER
340Skin IndurationOFFSIDES
341SpondylolisthesisOFFSIDES
342Squamous cell carcinoma of skinOFFSIDES
343Subcutaneous AbscessOFFSIDES
344SubileusOFFSIDES
345SynovitisOFFSIDES
346ThrombocytopeniaCanada Vigilance: 1Canada Vigilance
SIDER
347Tooth ExtractionOFFSIDES
348Tooth InfectionOFFSIDES
349Tooth LossOFFSIDES
350Tooth repairOFFSIDES
351Toxic Epidermal NecrolysisSIDER
352Unresponsive to verbal stimuliOFFSIDES
353Upset stomachSIDER
354Urge IncontinenceOFFSIDES
355Urine cytomegalovirus positiveOFFSIDES
356Urine sodium abnormalOFFSIDES
357Vascular calcificationOFFSIDES
358Vasculitis, Leukocytoclastic, Cutaneous16004023
18628445
CTD
359Venous thrombosis limbOFFSIDES
360Visual ImpairmentCanada Vigilance: 1Canada Vigilance
361Vitamin A DeficiencyOFFSIDES
362Vulvovaginal drynessOFFSIDES
363Weight GainOFFSIDES
364diagnostic procedureOFFSIDES
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