MetaADEDB 2.0 @ LMMD
lormetazepam
(FJIKWRGCXUCUIG-UHFFFAOYSA-N)
Structure
SMILES
Clc1ccc2c(c1)C(=NC(C(=O)N2C)O)c1ccccc1Cl
Type(s)
Approved
ATC code(s)
N05CD06
Molecular Formula:
C16H12Cl2N2O2
Molecular Weight:
335.185
Log P:
2.6262
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
52.9
CAS Number(s):
848-75-9
Synonym(s)
1.
lormetazepam
2.
methyllorazepam
External Link(s)
MeSHC023842
PubChem Compound13314
BindingDB50240409
ChEBI52993
CHEMBLCHEMBL22097
DrugBankDB13872
DrugCentral1608
IUPHAR/BPS Guide to PHARMACOLOGY7553
KEGGdr:D01657
Therapeutic Target DatabaseD0I8HJ
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
15'nucleotidase increasedOFFSIDES
2AcidosisOFFSIDES
3Acute graft versus host disease in intestineOFFSIDES
4Acute psychosisSIDER
5AgitationSIDER
6Altered state of consciousnessSIDER
7AmnesiaSIDER
8Anal erosionOFFSIDES
9AngerSIDER
10AngioedemaOFFSIDES
SIDER
11AnorexiaOFFSIDES
12AnuriaOFFSIDES
13AnxietySIDER
14ApathyOFFSIDES
15AstheniaSIDER
16AtaxiaSIDER
17AuraOFFSIDES
18AutomatismOFFSIDES
19BilirubinuriaOFFSIDES
20Blood alkaline phosphatase increasedOFFSIDES
21Blood creatine phosphokinase increasedOFFSIDES
22Blood fibrinogenOFFSIDES
23Blood sodiumOFFSIDES
24Blood uric acidOFFSIDES
25Bone marrow depressionOFFSIDES
26BradyphreniaSIDER
27Bronchoalveolar LavageOFFSIDES
28Cerebral atrophyOFFSIDES
29Chronic Obstructive Airway DiseaseOFFSIDES
30CirrhosisOFFSIDES
31Colonic Pseudo-ObstructionOFFSIDES
32Completed SuicideOFFSIDES
SIDER
33Concomitant disease progressionOFFSIDES
34ConstipationSIDER
35Coronary artery insufficiencyOFFSIDES
36DependenceSIDER
37Depressed Level of ConsciousnessSIDER
38Depression suicidalOFFSIDES
39DermatitisSIDER
40Device related infectionOFFSIDES
41Diaphragmatic HerniaOFFSIDES
42Dieulafoy's vascular malformationOFFSIDES
43DiplopiaSIDER
44Disease recurrenceOFFSIDES
45Disseminated Intravascular CoagulationOFFSIDES
46Disturbance in sexual arousalSIDER
47DizzinessSIDER
48Drug DependenceSIDER
49Drug withdrawal syndromeSIDER
50DysgeusiaSIDER
51DyslaliaOFFSIDES
52Dysthymic DisorderOFFSIDES
53Emotional disorderSIDER
54Eosinophilic myocarditisOFFSIDES
55EpilepsySIDER
56ErythromelalgiaOFFSIDES
57ExcoriationOFFSIDES
58Eye painOFFSIDES
59Fanconi SyndromeOFFSIDES
60FatigueSIDER
61Fatty LiverOFFSIDES
62Febrile NeutropeniaOFFSIDES
63Feeling abnormalSIDER
64GamblingOFFSIDES
65Gamma-Glutamyltransferase IncreasedOFFSIDES
66Gastric outlet obstructionOFFSIDES
67General physical health deteriorationOFFSIDES
68Head titubationOFFSIDES
69HeadacheSIDER
70Hepatic artery stenosisOFFSIDES
71HepatosplenomegalyOFFSIDES
72HepatotoxicityOFFSIDES
73HyperacusisSIDER
74HypercreatininaemiaOFFSIDES
75HypersensitivitySIDER
76HypospadiasOFFSIDES
77Intestinal ObstructionOFFSIDES
78Intestinal infarctionOFFSIDES
79Left Ventricular HypertrophyOFFSIDES
80Lumbar puncture abnormalOFFSIDES
81Memory Disorders12756510CTD
82Musculoskeletal discomfortSIDER
83MyalgiaSIDER
84NauseaSIDER
85NephrectomyOFFSIDES
86Ocular HypertensionOFFSIDES
87Optic NeuritisOFFSIDES
88OsteopeniaOFFSIDES
89Parotid gland inflammationOFFSIDES
90PeriarthritisOFFSIDES
91PhonophobiaOFFSIDES
92Polysubstance dependenceOFFSIDES
93Pre-EclampsiaOFFSIDES
94PruritusSIDER
95PsoriasisOFFSIDES
96Psychomotor Disorders12756510CTD
97Pulmonary HypertensionOFFSIDES
98RageSIDER
99RalesOFFSIDES
100Renal cystOFFSIDES
101Renal tubular disorderOFFSIDES
102Retinal Vein OcclusionOFFSIDES
103Rhabdomyolysis18842231CTD
OFFSIDES
104Sleep Initiation and Maintenance Disorders16025317CTD
105SomnolenceSIDER
106Stenotrophomonas infectionOFFSIDES
107Stevens-Johnson SyndromeOFFSIDES
108SubileusOFFSIDES
109Sudden deathOFFSIDES
110Suicide attemptSIDER
111SuicideSIDER
112Suture related complicationOFFSIDES
113TachycardiaSIDER
114TensionSIDER
115Thoracic vertebral fractureOFFSIDES
116ThrombophlebitisOFFSIDES
117Toxic Optic NeuropathyOFFSIDES
118Umbilical herniaOFFSIDES
119UrticariaSIDER
120Venous InsufficiencyOFFSIDES
121Visual ImpairmentSIDER
122VomitingSIDER
123nervous system disorderSIDER
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