Penicillin G
(JGSARLDLIJGVTE-MBNYWOFBSA-N)
Structure
- SMILES
- O=C(Cc1ccccc1)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)O)(C)C
- Type(s)
- Approved; Vet_approved
- ATC code(s)
- J01CE01; J01CE08; J01CR50; S01AA14
- Molecular Formula:
- C16H18N2O4S
- Molecular Weight:
- 334.390
- Log P:
- 1.1896
- Hydrogen Bond Acceptor:
- 7
- Hydrogen Bond Donor:
- 2
- TPSA:
- 112.01
- CAS Number(s):
- 61-33-6
Synonym(s)
1.
Penicillin G
2.
Benzylpenicillin
3.
Benpen
4.
Benzylpenicillin Potassium
5.
Coliriocilina
6.
Crystapen
7.
Or-pen
8.
Parcillin
9.
Pekamin
10.
Pengesod
11.
Penibiot
12.
Penicilina G Llorente
13.
Penicillin G Jenapharm
14.
Penicillin G Potassium
15.
Penicillin G Sodium
16.
Penicillin Grünenthal
17.
Penilevel
18.
Peniroger
19.
Pfizerpen
20.
Sodiopen
21.
Sodipen
22.
Sodium Benzylpenicillin
23.
Sodium Penicillin
24.
Unicilina
25.
Ursopen
26.
Van-Pen-G
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Urticaria | FAERS: 4 Canada Vigilance: 73 | Canada Vigilance US FAERS | |
| 2 | Toxic Epidermal Necrolysis | FAERS: 3 | US FAERS | |
| 3 | Erythema | FAERS: 2 Canada Vigilance: 29 | Canada Vigilance US FAERS | |
| 4 | Hypersensitivity | FAERS: 2 Canada Vigilance: 14 | Canada Vigilance US FAERS | |
| 5 | Pruritus | FAERS: 2 Canada Vigilance: 56 | Canada Vigilance US FAERS | |
| 6 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 7 | Angioedema | FAERS: 1 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 8 | Asthma | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 9 | Bronchospasm | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 10 | Cerebral Infarction | FAERS: 1 | US FAERS | |
| 11 | Circumstance or information capable of leading to medication error | FAERS: 1 | US FAERS | |
| 12 | Cutaneous lymphoma | FAERS: 1 | US FAERS | |
| 13 | Discomfort | FAERS: 1 | US FAERS | |
| 14 | Drug effect incomplete | FAERS: 1 | US FAERS | |
| 15 | Drug resistance | FAERS: 1 | OFFSIDES US FAERS | |
| 16 | Dysarthria | FAERS: 1 | US FAERS | |
| 17 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 18 | False positive investigation result | FAERS: 1 | US FAERS | |
| 19 | Flat affect | FAERS: 1 | US FAERS | |
| 20 | Headache | FAERS: 1 Canada Vigilance: 4 | 20188604 | CTD Canada Vigilance US FAERS |
| 21 | Injection site pain | FAERS: 1 | US FAERS | |
| 22 | Leukocytosis | FAERS: 1 | US FAERS | |
| 23 | Maternal exposure during pregnancy | FAERS: 1 | US FAERS | |
| 24 | Mental status changes | FAERS: 1 | US FAERS | |
| 25 | Oxygen consumption decreased | FAERS: 1 | US FAERS | |
| 26 | Pallor | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 27 | Post inflammatory pigmentation change | FAERS: 1 | US FAERS | |
| 28 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 29 | Rash erythematous | FAERS: 1 Canada Vigilance: 37 | Canada Vigilance US FAERS | |
| 30 | Romberg test positive | FAERS: 1 | US FAERS | |
| 31 | Shock | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 32 | Skin necrosis | FAERS: 1 | US FAERS | |
| 33 | Skin test positive | FAERS: 1 | OFFSIDES US FAERS | |
| 34 | Swelling | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 35 | Unevaluable event | FAERS: 1 | US FAERS | |
| 36 | Unresponsive to stimuli | FAERS: 1 | OFFSIDES US FAERS | |
| 37 | Vascular calcification | FAERS: 1 | US FAERS | |
| 38 | White matter lesion | FAERS: 1 | US FAERS | |
| 39 | Abdominal Pain | Canada Vigilance: 8 | 287446 4135565 | CTD Canada Vigilance |
| 40 | Abdominal discomfort | Canada Vigilance: 4 | Canada Vigilance | |
| 41 | Abdominal sepsis | OFFSIDES | ||
| 42 | Acidosis | 5722316 | CTD OFFSIDES | |
| 43 | Acne | Canada Vigilance: 3 | Canada Vigilance | |
| 44 | Actinomycosis | OFFSIDES | ||
| 45 | Acute kidney injury | 4176988 19755771 | CTD | |
| 46 | Acute prerenal failure | OFFSIDES | ||
| 47 | Acute respiratory failure | OFFSIDES | ||
| 48 | Agranulocytosis | Canada Vigilance: 1 | Canada Vigilance | |
| 49 | Alanine Aminotransferase Increased | OFFSIDES | ||
| 50 | Alcohol interaction | OFFSIDES | ||
| 51 | Amaurosis Fugax | OFFSIDES | ||
| 52 | Anaphylactic shock | Canada Vigilance: 5 | Canada Vigilance | |
| 53 | Anaphylactoid Reaction | Canada Vigilance: 2 | Canada Vigilance | |
| 54 | Anemia, Hemolytic | CTD | ||
| 55 | Anemia | 442760 | CTD | |
| 56 | Anuria | 2320016 | CTD OFFSIDES | |
| 57 | Apathy | Canada Vigilance: 1 | Canada Vigilance | |
| 58 | Apnea | OFFSIDES | ||
| 59 | Apparent death | Canada Vigilance: 1 | Canada Vigilance | |
| 60 | Appendectomy | OFFSIDES | ||
| 61 | Arthralgia | Canada Vigilance: 4 | Canada Vigilance | |
| 62 | Arthritis | Canada Vigilance: 1 | Canada Vigilance | |
| 63 | Arthropathy | Canada Vigilance: 1 | Canada Vigilance | |
| 64 | Ascites | OFFSIDES | ||
| 65 | Asthenia | Canada Vigilance: 5 | Canada Vigilance | |
| 66 | Automatism | OFFSIDES | ||
| 67 | Blindness | Canada Vigilance: 1 | Canada Vigilance | |
| 68 | Blood Coagulation Disorders | 62897 | CTD | |
| 69 | Blood albumin decreased | OFFSIDES | ||
| 70 | Blood alkaline phosphatase increased | OFFSIDES | ||
| 71 | Blood creatine decreased | OFFSIDES | ||
| 72 | Blood creatine phosphokinase decreased | OFFSIDES | ||
| 73 | Blood lactate dehydrogenase decreased | OFFSIDES | ||
| 74 | Blood pH decreased | OFFSIDES | ||
| 75 | Blood potassium increased | OFFSIDES | ||
| 76 | Blood pressure immeasurable | Canada Vigilance: 1 | Canada Vigilance | |
| 77 | Blood sodium | OFFSIDES | ||
| 78 | Blood urea increased | OFFSIDES | ||
| 79 | Brachial Plexus Neuritis | 12622755 | CTD | |
| 80 | Brain Diseases | 4951946 | CTD | |
| 81 | Bronchopneumonia | OFFSIDES | ||
| 82 | Burning sensation | Canada Vigilance: 1 | Canada Vigilance | |
| 83 | Cardiac enzymes increased | OFFSIDES | ||
| 84 | Catheter site related reaction | OFFSIDES | ||
| 85 | Cellulitis | OFFSIDES | ||
| 86 | Cerebellar infarction | OFFSIDES | ||
| 87 | Cerebral cyst | OFFSIDES | ||
| 88 | Chemical and Drug Induced Liver Injury | 11409000 | CTD | |
| 89 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 90 | Chest discomfort | Canada Vigilance: 2 | Canada Vigilance | |
| 91 | Chills | Canada Vigilance: 4 | Canada Vigilance | |
| 92 | Choking | Canada Vigilance: 1 | Canada Vigilance | |
| 93 | Confusion | 3046579 4951946 | CTD | |
| 94 | Consciousness Disorders | 6071378 | CTD | |
| 95 | Constipation | Canada Vigilance: 1 | Canada Vigilance | |
| 96 | Coronary Artery Disease | Canada Vigilance: 1 | Canada Vigilance | |
| 97 | Creatinine renal clearance decreased | OFFSIDES | ||
| 98 | Cyanosis | Canada Vigilance: 4 | Canada Vigilance | |
| 99 | Cystitis | CTD | ||
| 100 | Deafness | OFFSIDES | ||
| 101 | Dehydration | Canada Vigilance: 1 | Canada Vigilance | |
| 102 | Dental abscess | OFFSIDES | ||
| 103 | Dermatitis, Allergic Contact | 13761469 | CTD | |
| 104 | Dermatitis | Canada Vigilance: 6 | Canada Vigilance | |
| 105 | Dizziness | Canada Vigilance: 14 | Canada Vigilance | |
| 106 | Drug Eruptions | 12622755 | CTD | |
| 107 | Drug exposure during pregnancy | OFFSIDES | ||
| 108 | Dry skin | Canada Vigilance: 1 | Canada Vigilance | |
| 109 | Dyschezia | OFFSIDES | ||
| 110 | Dysphonia | Canada Vigilance: 1 | Canada Vigilance | |
| 111 | Dysuria | 9417722 10762126 | CTD | |
| 112 | Ear discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 113 | Endocarditis | 581353 | CTD OFFSIDES | |
| 114 | Enterococcal infection | OFFSIDES | ||
| 115 | Eosinophilia | 636917 | CTD | |
| 116 | Epilepsy | CTD | ||
| 117 | Epispadias | OFFSIDES | ||
| 118 | Erysipelas | OFFSIDES | ||
| 119 | Erythema Infectiosum | OFFSIDES | ||
| 120 | Escherichia infection | OFFSIDES | ||
| 121 | Esophageal Stenosis | OFFSIDES | ||
| 122 | Exanthema | 287446 636917 16943303 | CTD | |
| 123 | Eye excision | OFFSIDES | ||
| 124 | Factor VIII inhibition | OFFSIDES | ||
| 125 | Fatigue | Canada Vigilance: 1 | Canada Vigilance | |
| 126 | Fever | 636917 5668001 | CTD | |
| 127 | Flushing | Canada Vigilance: 3 | Canada Vigilance | |
| 128 | Gamma-Glutamyltransferase Increased | OFFSIDES | ||
| 129 | Gastritis | Canada Vigilance: 1 | Canada Vigilance | |
| 130 | Gastrointestinal infection | OFFSIDES | ||
| 131 | General physical health deterioration | OFFSIDES | ||
| 132 | Glossitis | Canada Vigilance: 1 | Canada Vigilance | |
| 133 | Gram-Negative Bacterial Infections | 4998180 | CTD | |
| 134 | Gram-Positive Bacterial Infections | 3654951 6176609 | CTD | |
| 135 | Granulocytosis | OFFSIDES | ||
| 136 | Hallucinations | 4951946 | CTD | |
| 137 | Hematuria | 2320016 9417722 19755771 | CTD | |
| 138 | Hemiparesis | OFFSIDES | ||
| 139 | Hemoglobinuria | 1173853 | CTD | |
| 140 | Hemorrhage | 6780799 | CTD | |
| 141 | Hepatic necrosis | OFFSIDES | ||
| 142 | Hiccough | OFFSIDES | ||
| 143 | Hydronephrosis | 19755771 | CTD | |
| 144 | Hypernatremia | 5722316 | CTD | |
| 145 | Hyperventilation | Canada Vigilance: 1 | Canada Vigilance | |
| 146 | Hypervigilance | OFFSIDES | ||
| 147 | Hypokalemia | 5722316 | CTD | |
| 148 | Hypokinesia | Canada Vigilance: 1 | Canada Vigilance | |
| 149 | Hypopituitarism | OFFSIDES | ||
| 150 | Hypopyon | OFFSIDES | ||
| 151 | Hypotension | Canada Vigilance: 6 | 490820 | CTD Canada Vigilance |
| 152 | Ileus | 4135565 | CTD | |
| 153 | Immune reconstitution syndrome | OFFSIDES | ||
| 154 | Infantile apnoeic attack | OFFSIDES | ||
| 155 | Infection | 6075112 | CTD | |
| 156 | Injection Site Reaction | Canada Vigilance: 2 | Canada Vigilance | |
| 157 | Injection site inflammation | Canada Vigilance: 1 | Canada Vigilance | |
| 158 | Injection site irritation | OFFSIDES | ||
| 159 | Injection site pruritus | OFFSIDES | ||
| 160 | Intention tremor | OFFSIDES | ||
| 161 | Joint stiffness | Canada Vigilance: 1 | Canada Vigilance | |
| 162 | Joint swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 163 | Kidney Diseases | 6363382 | CTD | |
| 164 | Klebsiella sepsis | OFFSIDES | ||
| 165 | Laceration | OFFSIDES | ||
| 166 | Lethargy | 490820 3046579 | CTD | |
| 167 | Leukoencephalopathy | OFFSIDES | ||
| 168 | Leukopenia | 442760 | CTD | |
| 169 | Limb discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 170 | Lip swelling | Canada Vigilance: 3 | Canada Vigilance | |
| 171 | Liver palpable subcostal | OFFSIDES | ||
| 172 | Lymphangiosis carcinomatosa | OFFSIDES | ||
| 173 | Malaise | Canada Vigilance: 2 | Canada Vigilance | |
| 174 | Medication Error | Canada Vigilance: 1 | Canada Vigilance | |
| 175 | Meningitis, Bacterial | 3654951 | CTD | |
| 176 | Meningitis, Haemophilus | 306816 | CTD | |
| 177 | Musculoskeletal stiffness | Canada Vigilance: 2 | Canada Vigilance | |
| 178 | Mushroom Poisoning | 19730819 | CTD | |
| 179 | Myalgia | Canada Vigilance: 1 | Canada Vigilance | |
| 180 | Mydriasis | Canada Vigilance: 1 | Canada Vigilance | |
| 181 | Myelitis | OFFSIDES | ||
| 182 | Myoclonus | CTD | ||
| 183 | Myoglobin blood increased | OFFSIDES | ||
| 184 | Nausea | Canada Vigilance: 18 | Canada Vigilance | |
| 185 | Neonatal respiratory failure | OFFSIDES | ||
| 186 | Nephritis, Interstitial | CTD | ||
| 187 | Neurosyphilis | 3827674 | CTD | |
| 188 | Neutropenia | Canada Vigilance: 1 | 5668001 6230485 | CTD Canada Vigilance |
| 189 | Neutropenic colitis | OFFSIDES | ||
| 190 | Neutrophil count decreased | OFFSIDES | ||
| 191 | Overdose | OFFSIDES | ||
| 192 | PO2 decreased | OFFSIDES | ||
| 193 | Pain | Canada Vigilance: 1 | 442760 3245335 12622755 | CTD Canada Vigilance |
| 194 | Palmar erythema | OFFSIDES | ||
| 195 | Pancytopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 196 | Pelvic Inflammatory Disease | 1173853 | CTD | |
| 197 | Peripheral swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 198 | Petechiae | Canada Vigilance: 1 | Canada Vigilance | |
| 199 | Pharyngeal swelling | Canada Vigilance: 2 | Canada Vigilance | |
| 200 | Pharyngolaryngeal Pain | OFFSIDES | ||
| 201 | Phlebitis | Canada Vigilance: 1 | Canada Vigilance | |
| 202 | Pituitary infarction | OFFSIDES | ||
| 203 | Pneumococcal Infections | 1495831 11328774 | CTD | |
| 204 | Pneumocystis jiroveci pneumonia | OFFSIDES | ||
| 205 | Pneumonia | 4998180 6028697 | CTD | |
| 206 | Polyhydramnios | OFFSIDES | ||
| 207 | Poor sucking reflex | OFFSIDES | ||
| 208 | Portal hypertensive gastropathy | OFFSIDES | ||
| 209 | Protein total decreased | OFFSIDES | ||
| 210 | Proteinuria | 16943303 | CTD | |
| 211 | Pulmonary percussion test abnormality | OFFSIDES | ||
| 212 | Pulmonary thrombosis | OFFSIDES | ||
| 213 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 214 | Reflex, Abnormal | 4998180 6028697 | CTD | |
| 215 | Renal Insufficiency | 8554694 10762126 | CTD | |
| 216 | Renal failure neonatal | OFFSIDES | ||
| 217 | Renal tubular necrosis | OFFSIDES | ||
| 218 | Rhabdomyolysis | OFFSIDES | ||
| 219 | Rhinitis | Canada Vigilance: 1 | Canada Vigilance | |
| 220 | Right Ventricular Hypertrophy | OFFSIDES | ||
| 221 | Seizures |
581353
2503015 3046579 3241957 3963457 4115818 4823950 4998180 6028697 6071378 6888804 9190241 16920157 17015947 18762233 | CTD | |
| 222 | Sepsis | 552491 | CTD | |
| 223 | Serum Sickness | Canada Vigilance: 4 | Canada Vigilance | |
| 224 | Skin Diseases, Bacterial | 7249889 | CTD | |
| 225 | Skin reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 226 | Somnolence | Canada Vigilance: 1 | Canada Vigilance | |
| 227 | Sopor | OFFSIDES | ||
| 228 | Staphylococcal Infections | 10762126 | CTD | |
| 229 | Status Epilepticus | 1389823 4951946 18762233 | CTD | |
| 230 | Stomach Diseases | 442760 | CTD | |
| 231 | Stomatococcal infection | OFFSIDES | ||
| 232 | Streptococcal Infections | CTD | ||
| 233 | Stridor | OFFSIDES | ||
| 234 | Surgical Wound Infection | 7064681 | CTD | |
| 235 | Syncope | Canada Vigilance: 3 | Canada Vigilance | |
| 236 | Syphilis | OFFSIDES | ||
| 237 | Tachycardia | Canada Vigilance: 2 | Canada Vigilance | |
| 238 | Temporal Arteritis | OFFSIDES | ||
| 239 | Tetany | OFFSIDES | ||
| 240 | Thrombocytopenia | 442760 5668001 | CTD | |
| 241 | Thrombophlebitis | OFFSIDES | ||
| 242 | Tinnitus | Canada Vigilance: 1 | Canada Vigilance | |
| 243 | Treatment related secondary malignancy | OFFSIDES | ||
| 244 | Ureteral Diseases | 37350 | CTD | |
| 245 | Ureteral obstruction | 19755771 | CTD | |
| 246 | Uterine Rupture | OFFSIDES | ||
| 247 | Vertigo | Canada Vigilance: 1 | Canada Vigilance | |
| 248 | Visual Impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 249 | Vomiting | Canada Vigilance: 14 | Canada Vigilance | |
| 250 | Vulvovaginal pruritus | Canada Vigilance: 1 | Canada Vigilance | |
| 251 | Wheezing | Canada Vigilance: 1 | Canada Vigilance | |
| 252 | Wound Debridement | OFFSIDES | ||
| 253 | anaphylaxis | 65671 | CTD |
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