MetaADEDB 2.0 @ LMMD
Oxacillin
(UWYHMGVUTGAWSP-JKIFEVAISA-N)
Structure
SMILES
OC(=O)[C@@H]1N2C(=O)[C@H]([C@H]2SC1(C)C)NC(=O)c1c(C)onc1c1ccccc1
Type(s)
Approved; Investigational
ATC code(s)
J01CF04; J01CR50
Molecular Formula:
C19H19N3O5S
Molecular Weight:
401.436
Log P:
2.2241
Hydrogen Bond Acceptor:
9
Hydrogen Bond Donor:
2
TPSA:
138.04
CAS Number(s):
66-79-5; 1173-88-2
Synonym(s)
1.
Oxacillin
2.
Oxazocilline
3.
Penicillin, Methylphenylisoxazolyl
4.
Sodium Oxacillin
5.
Oxacillin Sodium
6.
Oxacillin, Monosodium Salt, Anhydrous
7.
Oxacillin, Monosodium Salt, Monohydrate
8.
Prostaphlin
9.
Methylphenylisoxazolyl Penicillin
10.
Oxacillin, Sodium
11.
Sodium, Oxacillin
External Link(s)
MeSHD010068
PubChem Compound6196
BindingDB50292247
50350483
ChEBI7809
CHEMBLCHEMBL819
DrugBankDB00713
DrugCentral2006
KEGGcpd:C07334
dr:D08307
Therapeutic Target DatabaseD0MB8I
ZINC3875439
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1InfectionFAERS: 13US FAERS
2treatment failureFAERS: 11US FAERS
3Alanine Aminotransferase IncreasedFAERS: 7OFFSIDES
US FAERS
4Aspartate Aminotransferase IncreasedFAERS: 7SIDER
US FAERS
5Acute kidney injuryFAERS: 6US FAERS
6NeutropeniaFAERS: 5SIDER
US FAERS
7OverdoseFAERS: 4OFFSIDES
US FAERS
8FatigueFAERS: 3US FAERS
9MalaiseFAERS: 3SIDER
US FAERS
10White blood cell count decreasedFAERS: 3US FAERS
11AmnesiaFAERS: 2US FAERS
12Blood alkaline phosphatase increasedFAERS: 2OFFSIDES
US FAERS
13Blood creatinine increasedFAERS: 2US FAERS
14ChillsFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
15CyanosisFAERS: 2US FAERS
16DizzinessFAERS: 2US FAERS
17LeukopeniaFAERS: 2US FAERS
18NauseaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
19No adverse eventFAERS: 2US FAERS
20TremorFAERS: 2US FAERS
21AbscessFAERS: 1US FAERS
22AgitationFAERS: 1US FAERS
23Anaphylactic shockFAERS: 1SIDER
US FAERS
24Aphthous StomatitisFAERS: 1US FAERS
25ArthritisFAERS: 1US FAERS
26AstheniaFAERS: 1US FAERS
27Blood potassium decreasedFAERS: 1US FAERS
28CandidiasisFAERS: 1US FAERS
29Cells in urineFAERS: 1US FAERS
30Drug dose omissionFAERS: 1US FAERS
31Drug label confusionFAERS: 1US FAERS
32Drug resistanceFAERS: 1US FAERS
33ErythemaFAERS: 1
Canada Vigilance: 2
Canada Vigilance
US FAERS
34HeadacheFAERS: 1US FAERS
35HepatitisFAERS: 1OFFSIDES
US FAERS
36Histiocytosis haematophagicFAERS: 1US FAERS
37HypophagiaFAERS: 1US FAERS
38HypotensionFAERS: 1SIDER
US FAERS
39Inappropriate schedule of drug administrationFAERS: 1US FAERS
40Incorrect drug administration rateFAERS: 1US FAERS
41Medication ErrorFAERS: 1US FAERS
42Mixed liver injuryFAERS: 1US FAERS
43MyoclonusFAERS: 1US FAERS
44OliguriaFAERS: 1US FAERS
45PainFAERS: 1US FAERS
46PancytopeniaFAERS: 1SIDER
US FAERS
47PruritusFAERS: 1
Canada Vigilance: 7
Canada Vigilance
SIDER
US FAERS
48Respiratory FailureFAERS: 1OFFSIDES
US FAERS
49SyncopeFAERS: 1US FAERS
50ThrombocytopeniaFAERS: 1US FAERS
51ToothacheFAERS: 1US FAERS
52Urinary sediment presentFAERS: 1US FAERS
53UrticariaFAERS: 1
Canada Vigilance: 5
Canada Vigilance
SIDER
US FAERS
54VomitingFAERS: 1SIDER
US FAERS
55jaundiceFAERS: 1US FAERS
565'nucleotidase increasedOFFSIDES
57Abdominal PainSIDER
58Abdominal discomfortSIDER
59Abdominal sepsisOFFSIDES
60AcidosisOFFSIDES
61AgranulocytosisSIDER
62AngioedemaSIDER
63Angiogram cerebral abnormalOFFSIDES
64AnuriaOFFSIDES
65ArthralgiaSIDER
66Atrial thrombosisOFFSIDES
67Avascular necrosisOFFSIDES
68Bacteremia11337188CTD
69Bilirubin conjugated increasedOFFSIDES
70Blood ketone body increasedOFFSIDES
71Blood magnesium increasedOFFSIDES
72Blood sodiumOFFSIDES
73Bone marrow depressionSIDER
74Brain DeathOFFSIDES
75Brain scan abnormalOFFSIDES
76Bronchial secretion retentionOFFSIDES
77BronchospasmSIDER
78Candida sepsisOFFSIDES
79Catheter related infectionOFFSIDES
80Catheter site infectionOFFSIDES
81Chemical and Drug Induced Liver Injury

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CTD
82CholangiolitisOFFSIDES
83Cholestasis4025011CTD
84CirrhosisOFFSIDES
85Clostridium difficile colitisSIDER
86ColitisSIDER
87Congenital tricuspid valve incompetenceOFFSIDES
88Creatinine renal clearance decreasedOFFSIDES
89Cytolytic hepatitisOFFSIDES
90DermatitisSIDER
91Dermo-hypodermitisOFFSIDES
92Diffuse alveolar damageOFFSIDES
93DiscomfortSIDER
94Disseminated Intravascular CoagulationOFFSIDES
95Drug Eruptions11337188CTD
96Duodenal UlcerOFFSIDES
97DuodenitisOFFSIDES
98EczemaOFFSIDES
99Endoscopy gastrointestinal abnormalOFFSIDES
100Eosinophilia7436655CTD
SIDER
101Eosinophilic myocarditisOFFSIDES
102EpilepsyOFFSIDES
103ErysipelasOFFSIDES
104Erythema MultiformeCanada Vigilance: 1Canada Vigilance
105EscharOFFSIDES
106Exanthema9161625
18307421
CTD
107Feeling abnormalSIDER
108Gamma-Glutamyltransferase IncreasedOFFSIDES
109GangreneOFFSIDES
110Gastrointestinal PainSIDER
111General physical conditionOFFSIDES
112General physical health deteriorationOFFSIDES
113GranulocytosisOFFSIDES
114HepatosplenomegalyOFFSIDES
115HepatotoxicitySIDER
116Human herpesvirus 8 infectionOFFSIDES
117HypersensitivitySIDER
118HypersplenismOFFSIDES
119Hypokalemia3215112CTD
120Hypoplastic Left Heart SyndromeOFFSIDES
121HypoxiaOFFSIDES
122Implant site infectionOFFSIDES
123Jaundice, Obstructive3578231
4025011
CTD
124Kidney FailureOFFSIDES
125Lactate pyruvate ratio increasedOFFSIDES
126LaryngospasmSIDER
127Leukopenia neonatalOFFSIDES
128Lung consolidationOFFSIDES
129MediastinitisOFFSIDES
130Medical device complicationOFFSIDES
131Metabolic acidosisOFFSIDES
132Multiple drug overdoseOFFSIDES
133Musculoskeletal discomfortSIDER
134MyalgiaSIDER
135MyelodysplasiaOFFSIDES
136Nephritis allergicOFFSIDES
137Nephritis, Interstitial7436655CTD
138Nephrotic SyndromeOFFSIDES
139Neurological examination abnormalOFFSIDES
140Neurotoxicity Syndromes3335815CTD
141Pericarditis20585370CTD
142PhimosisOFFSIDES
143Phlebitis9161625CTD
144Protein urine presentSIDER
145ProteinuriaSIDER
146Pulmonary HypertensionOFFSIDES
147Reaction gastrointestinalSIDER
148Red man syndromeOFFSIDES
149Renal Insufficiency11337188CTD
150Renal cystOFFSIDES
151Renal tubular necrosisOFFSIDES
152Seizures401945
4115818
CTD
153Septic ShockOFFSIDES
154Serum SicknessSIDER
155ShockSIDER
156Skin lesionOFFSIDES
157SpondylitisOFFSIDES
158Staphylococcal Infections

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CTD
159Staphylococcal Skin Infections15889357CTD
160StomatitisSIDER
161Therapeutic response unexpected with drug substitutionOFFSIDES
162Transaminases increasedOFFSIDES
163Transient psychosisOFFSIDES
164Unresponsive to verbal stimuliOFFSIDES
165Vasculitis, Leukocytoclastic, Cutaneous11337188CTD
166Venous occlusionOFFSIDES
167pseudomembranous colitisSIDER
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