Cephalothin
(XIURVHNZVLADCM-IUODEOHRSA-N)
Structure
- SMILES
- CC(=O)OCC1=C(C(=O)O)N2[C@H](SC1)[C@@H](C2=O)NC(=O)Cc1cccs1
- Type(s)
- Approved; Investigational; Vet_approved
- ATC code(s)
- J01DB03
- Molecular Formula:
- C16H16N2O6S2
- Molecular Weight:
- 396.438
- Log P:
- 0.9211
- Hydrogen Bond Acceptor:
- 10
- Hydrogen Bond Donor:
- 2
- TPSA:
- 166.55
- CAS Number(s):
- 153-61-7
Synonym(s)
1.
Cephalothin
2.
Cefalotin
3.
Sodium Cephalothin
4.
Cefalotina Normon
5.
Cefalotina Sodica Spaly
6.
Ceftina
7.
Cephalothin Monosodium Salt
8.
Keflin
9.
Seffin
10.
Cephalothin, Sodium
11.
Monosodium Salt, Cephalothin
12.
Salt, Cephalothin Monosodium
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Abdominal Pain | Canada Vigilance: 3 | Canada Vigilance | |
| 2 | Abscess | 4850936 | CTD | |
| 3 | Acute kidney injury | CTD | ||
| 4 | Anemia, Hemolytic | CTD | ||
| 5 | Anuria | 4122055 4678426 | CTD | |
| 6 | Aspartate Aminotransferase Increased | Canada Vigilance: 1 | Canada Vigilance | |
| 7 | Asthenia | Canada Vigilance: 1 | Canada Vigilance | |
| 8 | Bacterial Infections | 736504 | CTD | |
| 9 | Blood creatinine increased | Canada Vigilance: 1 | Canada Vigilance | |
| 10 | Blood urea increased | Canada Vigilance: 1 | Canada Vigilance | |
| 11 | Bronchopneumonia | 958099 | CTD | |
| 12 | Bronchospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 13 | Cardiac Arrest | Canada Vigilance: 1 | Canada Vigilance | |
| 14 | Chemical and Drug Induced Liver Injury | CTD | ||
| 15 | Conjunctivitis | Canada Vigilance: 1 | Canada Vigilance | |
| 16 | Creatinine renal clearance decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 17 | Dizziness | Canada Vigilance: 1 | Canada Vigilance | |
| 18 | Drug Eruptions | 6674550 | CTD | |
| 19 | Eosinophilia | Canada Vigilance: 1 | 636917 4408153 4800729 | CTD Canada Vigilance |
| 20 | Epilepsy | 8487076 | CTD | |
| 21 | Erythema | Canada Vigilance: 2 | Canada Vigilance | |
| 22 | Escherichia coli Infections | 893241 1107297 4850936 | CTD | |
| 23 | Exanthema | CTD | ||
| 24 | Fanconi Syndrome | 343914 | CTD | |
| 25 | Fever | CTD | ||
| 26 | Flushing | Canada Vigilance: 2 | Canada Vigilance | |
| 27 | Headache | Canada Vigilance: 1 | Canada Vigilance | |
| 28 | Heart Diseases | 3409104 | CTD | |
| 29 | Hematuria | 4408153 4826627 | CTD | |
| 30 | Hyperbilirubinemia | 5437593 | CTD | |
| 31 | Hypokalemia | 4110324 | CTD | |
| 32 | Infection | 6674550 | CTD | |
| 33 | Inflammation | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Injection site inflammation | Canada Vigilance: 1 | Canada Vigilance | |
| 35 | Kidney Diseases | CTD | ||
| 36 | Klebsiella Infections | 4850936 | CTD | |
| 37 | Leukocytosis | 4800729 | CTD | |
| 38 | Leukopenia | Canada Vigilance: 1 | 5437593 | CTD Canada Vigilance |
| 39 | Nausea | Canada Vigilance: 2 | Canada Vigilance | |
| 40 | Nephritis, Interstitial | CTD | ||
| 41 | Neutropenia | Canada Vigilance: 1 | Canada Vigilance | |
| 42 | Oliguria | 1130924 1130930 | CTD | |
| 43 | Oral candidiasis | Canada Vigilance: 1 | Canada Vigilance | |
| 44 | Pelvic Inflammatory Disease | 1173853 | CTD | |
| 45 | Petechiae | Canada Vigilance: 1 | Canada Vigilance | |
| 46 | Phlebitis | Canada Vigilance: 3 | CTD Canada Vigilance | |
| 47 | Pneumonia | Canada Vigilance: 1 | 4850936 | CTD Canada Vigilance |
| 48 | Proteinuria | 4408153 | CTD | |
| 49 | Proteus Infections | 1107297 | CTD | |
| 50 | Pruritus | Canada Vigilance: 13 | 4408153 | CTD Canada Vigilance |
| 51 | Pseudomonas Infections | 4850936 | CTD | |
| 52 | Rash erythematous | Canada Vigilance: 6 | Canada Vigilance | |
| 53 | Rectal Diseases | 4850936 | CTD | |
| 54 | Renal Insufficiency | 60663 424834 | CTD | |
| 55 | Renal tubular necrosis | Canada Vigilance: 1 | Canada Vigilance | |
| 56 | Respiratory arrest | Canada Vigilance: 1 | Canada Vigilance | |
| 57 | Sepsis | 4850936 | CTD | |
| 58 | Serum Sickness | Canada Vigilance: 1 | Canada Vigilance | |
| 59 | Staphylococcal Infections | CTD | ||
| 60 | Streptococcal Infections | 789268 5697520 | CTD | |
| 61 | Stupor | Canada Vigilance: 1 | Canada Vigilance | |
| 62 | Supraventricular tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 63 | Surgical Wound Infection | 893241 | CTD | |
| 64 | Tachycardia | 5068082 | CTD | |
| 65 | Thrombophlebitis | 791101 5697520 | CTD | |
| 66 | Urticaria | Canada Vigilance: 8 | Canada Vigilance | |
| 67 | Vomiting | Canada Vigilance: 3 | Canada Vigilance | |
| 68 | anaphylaxis | 65671 | CTD | |
| 69 | jaundice | Canada Vigilance: 1 | Canada Vigilance |
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