MetaADEDB 2.0 @ LMMD
Roxithromycin
(RXZBMPWDPOLZGW-XMRMVWPWSA-N)
Structure
SMILES
COCCOCO/N=C/1\[C@H](C)C[C@@](C)(O)[C@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@H](C)[C@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C(=O)O[C@@H]([C@@]([C@@H]([C@H]1C)O)(C)O)CC)C
Type(s)
Approved; Investigational; Withdrawn
ATC code(s)
J01FA06
Molecular Formula:
C41H76N2O15
Molecular Weight:
837.047
Log P:
2.2096
Hydrogen Bond Acceptor:
17
Hydrogen Bond Donor:
5
TPSA:
216.89
CAS Number(s):
80214-83-1
Synonym(s)
1.
Roxithromycin
2.
Biaxsig
3.
Claramid
4.
Infectoroxit
5.
MTW-Roxithromycin
6.
Macrosil
7.
RU 28965
8.
RU 965
9.
RU-28965
10.
RU-965
11.
Rotesan
12.
Rotramin
13.
Roxi 1A Pharma
14.
Roxi Basics
15.
Roxi TAD
16.
Roxi-Puren
17.
Roxi-Q
18.
Roxi-Wolff
19.
Roxi-paed 1A Pharma
20.
Roxi-saar
21.
Roxibeta
22.
Roxigamma
23.
Roxigrün
24.
Roxihexal
25.
Roxithro-Lich
26.
Rulid
27.
Rulide
28.
roxi von ct
29.
roxidura
30.
RU28965
31.
RU965
External Link(s)
MeSHD015575
PubChem Compound6915744
BindingDB50248154
ChEBI48935
48844
CHEMBLCHEMBL1214185
DrugBankDB00778
DrugCentral2410
KEGGcpd:C13173
dr:D01710
Therapeutic Target DatabaseD0Y4FL
ZINC96061888
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal Compartment SyndromeOFFSIDES
2AcidosisOFFSIDES
3Acute bronchitisOFFSIDES
4Acute cholestatic hepatitisSIDER
5Acute kidney injury14766998CTD
6Alanine Aminotransferase IncreasedOFFSIDES
7AlveolitisOFFSIDES
8AmphetaminesOFFSIDES
9Anaphylactic shockSIDER
10AngioedemaOFFSIDES
SIDER
11Angle Closure GlaucomaOFFSIDES
12AnorexiaOFFSIDES
SIDER
13AscitesOFFSIDES
14AsthmaSIDER
15Atrial hypertrophyOFFSIDES
16Blood GlucoseOFFSIDES
17Blood alkaline phosphatase increasedOFFSIDES
18Blood chloride decreasedOFFSIDES
19Blood cholesterolOFFSIDES
20Blood creatine phosphokinase increasedOFFSIDES
21Blood creatinine increasedOFFSIDES
22Blood electrolytes abnormalOFFSIDES
23Blood fibrinogen increasedOFFSIDES
24Blood phosphorus decreasedOFFSIDES
25Blood phosphorus increasedOFFSIDES
26Blood sodiumOFFSIDES
27Blood triglycerides increasedOFFSIDES
28Brain DeathOFFSIDES
29Bronchial ObstructionOFFSIDES
30BronchospasmSIDER
31Chemical and Drug Induced Liver Injury14766998CTD
32ChokingOFFSIDES
33Chronic left ventricular failureOFFSIDES
34Chronic respiratory failureOFFSIDES
35Clostridium difficile colitisOFFSIDES
36ColitisOFFSIDES
37Creatinine renal clearance decreasedOFFSIDES
38Cryptosporidiosis11362904CTD
39Cytolytic hepatitisOFFSIDES
40Cytomegalovirus chorioretinitisOFFSIDES
41DeafnessSIDER
42DehydrationOFFSIDES
43Dental FistulaOFFSIDES
44Depressed Level of ConsciousnessOFFSIDES
45DermatitisSIDER
46DermatomyositisOFFSIDES
47DiscomfortSIDER
48DizzinessOFFSIDES
SIDER
49Drug Eruptions11792017CTD
50DyspepsiaSIDER
51Dyspnoea exacerbatedOFFSIDES
52Electromechanical dissociationOFFSIDES
53EmpyemaOFFSIDES
54EosinophiliaSIDER
55Eosinophilic PneumoniaOFFSIDES
56Eosinophilic myocarditisOFFSIDES
57Epidermal growth factor receptor increasedOFFSIDES
58Epigastric painSIDER
59EpistaxisOFFSIDES
60ErysipelasOFFSIDES
61Erythema MultiformeOFFSIDES
SIDER
62Exanthema11444584CTD
63Feeling abnormalSIDER
64FlatulenceSIDER
65Gamma-Glutamyltransferase IncreasedOFFSIDES
66Genital erosionOFFSIDES
67GoiterOFFSIDES
68HIV Wasting SyndromeOFFSIDES
69HeadacheSIDER
70Hepatic Veno-Occlusive Disease16595573CTD
71Hepatitis B positiveOFFSIDES
72Hepatitis11444584CTD
73HepatotoxicityOFFSIDES
74HyperreflexiaOFFSIDES
75HypersensitivitySIDER
76ImpetigoOFFSIDES
77Inflammation17524151
18197913		CTD
78Intentional misuseOFFSIDES
79Joint sprainOFFSIDES
80Large intestine perforationOFFSIDES
81LaryngospasmOFFSIDES
82LaryngotracheitisOFFSIDES
83Limb operationOFFSIDES
84Lip erosionOFFSIDES
85Livedo ReticularisOFFSIDES
86Liver Failure, Acute11444584CTD
87Low Cardiac Output SyndromeOFFSIDES
88Lung diseases18197913CTD
89LymphedemaOFFSIDES
90LymphoceleOFFSIDES
91MalaiseSIDER
92Metabolic acidosisOFFSIDES
93Metastatic Renal Cell CarcinomaOFFSIDES
94Muscle necrosisOFFSIDES
95Myoglobin blood increasedOFFSIDES
96NauseaOFFSIDES
SIDER
97Nonspecific reactionOFFSIDES
98Olfaction Disorders14676161CTD
99OnychoclasisOFFSIDES
100Optic NeuropathyOFFSIDES
101OsteomyelitisOFFSIDES
102PallorOFFSIDES
103PancreatitisSIDER
104Pharyngolaryngeal PainOFFSIDES
105Pneumocystis jiroveci pneumoniaOFFSIDES
106PolyuriaOFFSIDES
107Primary sequestrumOFFSIDES
108Productive CoughOFFSIDES
109Prothrombin level decreasedOFFSIDES
110PruritusSIDER
111Pulmonary congestionOFFSIDES
112PurpuraSIDER
113PurulenceOFFSIDES
114RalesOFFSIDES
115Renal Insufficiency12380704CTD
116Retinal vascular occlusionOFFSIDES
117Rhabdomyolysis12380704CTD
OFFSIDES
118Sputum culture positiveOFFSIDES
119Stevens-Johnson SyndromeOFFSIDES
SIDER
120Tachycardia9621142CTD
121ThrombocytosisSIDER
122TinnitusSIDER
123Torsades de Pointes12822762CTD
124Transaminases increasedOFFSIDES
125Urticaria9621142
11792017		CTD
SIDER
126Vaginal contraceptive device expelledOFFSIDES
127Vascular Diseases17164692CTD
128Vascular purpuraSIDER
129VertigoSIDER
130VomitingSIDER
131Vulvar erosionOFFSIDES
132jaundice11444584CTD
SIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120295

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.